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7097981 |
Reaction wells, assembly thereof, immunoassay apparatus and method using such well assemblies
The present invention relates mainly to reaction vessels, to sets of such vessels for automatic immunological assay apparatuses, to automatic immunological assay apparatuses making use of such sets...
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7094871 |
Solid phase native chemical ligation of unprotected or N-terminal cysteine protected peptides in aqueous solution
The present invention provides methods, apparatus and kits for synthesizing assembled peptides and proteins on a solid phase with sequential ligation of three or more unprotected peptide segments...
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7094537 |
Micro arrays with structured and unstructured probes
The invention provides an apparatus and method for determining a signal produced by a micro array device. The apparatus provides an unstructured probe and structured probe. The unstructured probe...
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7090803 |
Lateral flow immunoassay device
A lateral flow immunoassay test device that includes a housing with an elongated slot for holding a test sample collector; an elongated holder member for securing at least one immunoassay test...
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7091033 |
Array of toxicologically relevant canine genes and uses thereof
The invention provides for canine genes indicative of toxicological responses to agents such as drugs, pharmaceutical compounds, or chemicals. Methods of identifying and isolating toxicologically...
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7087203 |
Methods and apparatus for blood typing with optical bio-disc
This invention relates to clinical diagnostic assays and related optical bio-discs and a disc-reading apparatus. The invention is directed to a method for determining the blood cell type of an...
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7080478 |
Technology for cultivation of Porphyra and other seaweeds in land-based sea water ponds
The present invention provides unique technology, systems and methods of cultivating different types of seaweeds, including, but not limited to, Porphyra (Nori), Laminaria, Undaria, Eucheuma,...
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7078505 |
Manufacture of arrays with varying deposition parameters
Methods are disclosed for synthesizing a plurality of compounds on the surface of supports. The synthesis comprises a series of cycles of steps in which reagents for conducting the synthesis are...
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7070961 |
Electronically mediated nucleic acid amplification in NASBA
A method of improving amplification of nucleic acids using a nucleic acid sequence-based amplification (“NASBA”) method is provided wherein target nucleic acids and NASBA primers are...
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7070921 |
Molecular modification assays
Assays for detecting molecular modifications such as phosphate modifications and the presence and/or activity of enzymes and other agents involved in facilitating or otherwise regulating such...
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7067253 |
Method and device for identifying a polymer
The invention relates to a method for identifying a first polymer ( 4, 7 ) which is bonded to a first phase ( 5 ) that reflects electromagnetic waves. Said method comprises the following steps: (a)...
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7067293 |
Nanoengineered biophotonic hybrid device
An improved method for the design and development of high performance hybrid devices having biological and nonbiological components. A figure of merit is developed for the biological component or...
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7069152 |
Apparatus for identifying peptides and proteins by mass spectrometry
An apparatus for identifying a protein, polypeptide or peptide by means of mass spectrometry and especially by tandem mass spectrometry is disclosed. The apparatus preferably functions to model the...
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7067306 |
Device containing cytophilic islands that adhere cells separated by cytophobic regions
The invention provides a device for adhering cells in a specific and predetermined position, and associated methods. The device includes a plate defining a surface and a plurality of cytophilic...
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7060948 |
Temperature control method and apparatus for driving polymerase chain reaction (PCR) chip
Provided are a temperature control method and apparatus for driving a polymerize chain reaction (PCR) chip. In the temperature control apparatus, which is for a polymerize chain reaction chip, PCR...
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7060489 |
Protein chip holding tool
The present invention is object to provide a protein chip holding tool that is capable of effectively executing analysis work by preventing protein from being denatured and/or inactivated due to...
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7056722 |
Apparatus and method of preparation of stable, long term thrombin from plasma and thrombin formed thereby
A sterile method for preparing stable thrombin component from a single donor's plasma in which the thrombin component is harvested simultaneously from the clotting and adhesive proteins component...
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7053208 |
Dioxetane labeled probes and detection assays employing the same
Probes labeled with 1,2-dioxetane precursors can be employed in a variety of assays. The probes may be nucleic acid, peptide nucleic acid, proteins including enzyme, antibody or antigen, steroid,...
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7052858 |
Diagnostic assays for detection of Cryptosporidium parvum
This invention provides a novel Cryptosporidium parvum protein disulfide isomerase polypeptide, and nucleic acids that encode this polypeptide. The invention also provides methods, reagents, and...
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7049068 |
Microelectronic device for electrochemical detection of nucleic acid hybridization
A method of detecting a nucleic acid (e.g., DNA, RNA) that contains at least one preselected base (e.g., adenine, guanine, 6-mercaptoguanine, 8-oxo-guanine, and 8-oxo-adenine) comprises (a)...
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7041468 |
Blood glucose tracking apparatus and methods
A measurement module for glucose testing includes a glucose testing measurement module housing, a test strip receptacle formed in the housing, and a connector portion formed in the housing and...
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7037694 |
Method for treating liquid materials
A method for treating a biological organism in a medium, comprising heating the medium containing the organism by a temperature of at least about 2° C. at a rate which exceeds a relaxation rate of...
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7037659 |
Apparatus for constructing DNA probes having a prismatic and kaleidoscopic light homogenizer
The present invention provides an apparatus for constructing arrays of DNA sequences using the image of a micromirror array projected on a reaction site using a highly uniform beam of light...
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7037642 |
Removing compounds from blood products with porous particles immobilized in a matrix
Methods and devices are provided for reducing the concentration of low molecular weight compounds in a biological composition containing cells while substantially maintaining a desired biological...
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7033754 |
Decoding of array sensors with microspheres
The invention relates to compositions and methods for decoding microsphere array sensors.
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7033820 |
Automated system for isolating and amplifying a target nucleic acid sequence
An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples...
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7030217 |
Solid phase native chemical ligation of unprotected or N-terminal cysteine protected peptides in aqueous solution
The present invention provides methods, apparatus and kits for synthesizing assembled peptides and proteins on a solid phase with sequential ligation of three or more unprotected peptide segments...
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7026124 |
Method and multiple reservoir apparatus for fabrication of biomolecular arrays
Methods and apparatus for delivering a plurality of different biological materials onto discrete locations on a receiving surface, as for example to fabricate an array of different biological...
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7022477 |
Detection of target substances utilizing biochemically specific binding reaction
A composite material sheet which is composed of partitions two-dimensionally extending on a sheet plane to form on the sheet plane plural fine sections surrounded by the partitions and porous...
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7022505 |
Apparatus and method for ultrasonic treatment of a liquid
The present invention is an apparatus for ultrasonically treating a liquid to generate a product. The apparatus is capable of treating a continuously-flowing, or intermittently-flowing, liquid...
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7022473 |
Substrates for immobilizing and amplifying DNA and DNA-immobilized chips
Substrates for producing a DNA library are produced by immobilizing DNA onto a suitable substrate having excellent thermal conductivity. A surface of the substrate is chemically modified with a...
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7014823 |
Biomolecular-based actuator
This invention relates to actuators having biologically-based components, and methods of making and using the same. The actuator of the invention has a movable member that moves substantially...
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7011945 |
Random array of micro-spheres for the analysis of nucleic acids
A method of identifying nucleic acid samples comprising: providing a mircoarray including a substrate coated with a composition including a population of micro-spheres dispersed in a fluid...
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7008769 |
Nanoscale molecular arrayer
The present invention is a dedicated apparatus for the formation of array that includes one or more deposition domains comprised of one or more deposition materials. The present invention may...
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7010432 |
Method and system for determining the acceptability of signal data collected from a prothrombin time test strip
A method for determining the acceptability of signal data collected from a prothrombin time (PT) test strip includes collecting PT signal data from an assay area and control areas of the PT test...
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7005259 |
Methods for array preparation using substrate rotation
Methods are provided for the preparation of polymer arrays on wafers wherein the wafers are rotated between synthesis steps to provide more uniform results across the entire wafer.
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7001572 |
Analyzing device with biochip
The invention concerns a device for analyzing at least an analyte, comprising a container and a biochip defining together at least a section, attached to the container by a suitable adhesive. The...
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6998230 |
Array fabrication with drop detection
A drop deposition apparatus, and a method and computer program products using the drop deposition apparatus, for fabricating at least one addressable array of biopolymers on a substrate. The drop...
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6998274 |
Composite arrays utilizing microspheres
The invention relates to compositions and methods for decoding microsphere array sensors.
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6998236 |
Methods for detecting interaction between a test moiety and a plurality of target moieties
This invention relates generally to the field of microarray technology. In particular, the invention provides an integrated microarray device, which device comprises a substrate comprising a...
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6994972 |
Porous substrates for DNA arrays
A planar, rigid substrate made from a porous, inorganic material coated with cationic polymer molecules for attachment of an array of biomolecules, such as DNA, RNA, oligonucleotides, peptides, and...
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6989234 |
Method and apparatus for non-contact electrostatic actuation of droplets
An apparatus for actuating a droplet comprises a first conductive layer, a second conductive layer, a conductive elongate element, and a voltage source. The first conductive layer comprises a first...
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6979576 |
Methods of use of one step immunochromatographic device for Streptococcus A antigen
A method to determine the presence or absence of Streptococcus Group A antigen in a sample, comprising the following steps: extracting the antigen from the sample in an assay chamber with two or...
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6977145 |
Method for carrying out a biochemical protocol in continuous flow in a microreactor
Devices and methods for carrying out a chemical or biochemical protocol are disclosed. In one embodiment, the chemical or biochemical protocol is performed by cycling at least one thermal transfer...
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6977149 |
Biochemical reaction detection apparatus
A biochemical reaction detection chip capable of controlling the temperature for biochemical reactions including hybridizations and its substrate. The function of the chip is performed by...
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6972184 |
Cell motility assay
An electrooptical method is disclosed for quantifying the motility response of cells to external stimuli, wherein a target cell population (formed as a function of said response) is subsequently...
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6965433 |
Optical biodiscs with reflective layers
An optical biodisc has a substrate, a first reflective layer over the substrate, an opening in the first reflective layer for receiving an investigational feature, and a second reflective layer...
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6964857 |
Measuring indigenous photosynthetic organisms to detect chemical warefare agents in water
A method of testing water to detect the presence of a chemical or biological warfare agent is disclosed. The method is carried out by establishing control data by providing control water containing...
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6962782 |
Method for producing addressed ligands matrixes on a support
A method for fabricating matrices of addressed ligands on a carrier. In the method, an element is used such as a reservoir filled with ligand and containing an electrode to deposit and...
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6958221 |
Cell flow apparatus and method for real-time measurements of patient cellular responses
The present invention is directed to a method for determining the effect of each of a plurality of test agents on cells from a subject, and a method to profile patient cell responses to test agents.
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