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7129046 Linking to chemical array assemblies with metal layers  
A method of producing a front surface modified substrate, which substrate includes a metal layer, and which is useful in the fabrication of an array of multiple probes bonded to a front surface of...
7129047 Method for manufacturing a nucleotide detector  
A nucleotide detector 10 includes: metal particles 12 having a size of the order of nanometers (diameter: about 6 nm) placed on a surface of a substrate 11 at high density with high precision...
7109024 Biomolecule-bound substrates  
This invention features a biomolecule-bound substrate that includes a support made of an organic polymer and having an unmodified surface; and a plurality of unmodified biomolecules immobilized on...
7097981 Reaction wells, assembly thereof, immunoassay apparatus and method using such well assemblies  
The present invention relates mainly to reaction vessels, to sets of such vessels for automatic immunological assay apparatuses, to automatic immunological assay apparatuses making use of such...
7094537 Micro arrays with structured and unstructured probes  
The invention provides an apparatus and method for determining a signal produced by a micro array device. The apparatus provides an unstructured probe and structured probe. The unstructured probe...
7090803 Lateral flow immunoassay device  
A lateral flow immunoassay test device that includes a housing with an elongated slot for holding a test sample collector; an elongated holder member for securing at least one immunoassay test...
7091033 Array of toxicologically relevant canine genes and uses thereof  
The invention provides for canine genes indicative of toxicological responses to agents such as drugs, pharmaceutical compounds, or chemicals. Methods of identifying and isolating toxicologically...
7087203 Methods and apparatus for blood typing with optical bio-disc  
This invention relates to clinical diagnostic assays and related optical bio-discs and a disc-reading apparatus. The invention is directed to a method for determining the blood cell type of an...
7080478 Technology for cultivation of Porphyra and other seaweeds in land-based sea water ponds  
The present invention provides unique technology, systems and methods of cultivating different types of seaweeds, including, but not limited to, Porphyra (Nori), Laminaria, Undaria, Eucheuma,...
7078505 Manufacture of arrays with varying deposition parameters  
Methods are disclosed for synthesizing a plurality of compounds on the surface of supports. The synthesis comprises a series of cycles of steps in which reagents for conducting the synthesis are...
7070921 Molecular modification assays  
Assays for detecting molecular modifications such as phosphate modifications and the presence and/or activity of enzymes and other agents involved in facilitating or otherwise regulating such...
7070961 Electronically mediated nucleic acid amplification in NASBA  
A method of improving amplification of nucleic acids using a nucleic acid sequence-based amplification (“NASBA”) method is provided wherein target nucleic acids and NASBA primers are...
7069152 Apparatus for identifying peptides and proteins by mass spectrometry  
An apparatus for identifying a protein, polypeptide or peptide by means of mass spectrometry and especially by tandem mass spectrometry is disclosed. The apparatus preferably functions to model...
7067293 Nanoengineered biophotonic hybrid device  
An improved method for the design and development of high performance hybrid devices having biological and nonbiological components. A figure of merit is developed for the biological component or...
7067253 Method and device for identifying a polymer  
The invention relates to a method for identifying a first polymer (4, 7) which is bonded to a first phase (5) that reflects electromagnetic waves. Said method comprises the following steps: (a)...
7060948 Temperature control method and apparatus for driving polymerase chain reaction (PCR) chip  
Provided are a temperature control method and apparatus for driving a polymerize chain reaction (PCR) chip. In the temperature control apparatus, which is for a polymerize chain reaction chip, PCR...
7060489 Protein chip holding tool  
The present invention is object to provide a protein chip holding tool that is capable of effectively executing analysis work by preventing protein from being denatured and/or inactivated due to...
7056722 Apparatus and method of preparation of stable, long term thrombin from plasma and thrombin formed thereby  
A sterile method for preparing stable thrombin component from a single donor's plasma in which the thrombin component is harvested simultaneously from the clotting and adhesive proteins component...
7052858 Diagnostic assays for detection of Cryptosporidium parvum  
This invention provides a novel Cryptosporidium parvum protein disulfide isomerase polypeptide, and nucleic acids that encode this polypeptide. The invention also provides methods, reagents, and...
7053208 Dioxetane labeled probes and detection assays employing the same  
Probes labeled with 1,2-dioxetane precursors can be employed in a variety of assays. The probes may be nucleic acid, peptide nucleic acid, proteins including enzyme, antibody or antigen, steroid,...
7049068 Microelectronic device for electrochemical detection of nucleic acid hybridization  
A method of detecting a nucleic acid (e.g., DNA, RNA) that contains at least one preselected base (e.g., adenine, guanine, 6-mercaptoguanine, 8-oxo-guanine, and 8-oxo-adenine) comprises (a)...
7041468 Blood glucose tracking apparatus and methods  
A measurement module for glucose testing includes a glucose testing measurement module housing, a test strip receptacle formed in the housing, and a connector portion formed in the housing and...
7037694 Method for treating liquid materials  
A method for treating a biological organism in a medium, comprising heating the medium containing the organism by a temperature of at least about 2° C. at a rate which exceeds a relaxation rate of...
7037659 Apparatus for constructing DNA probes having a prismatic and kaleidoscopic light homogenizer  
The present invention provides an apparatus for constructing arrays of DNA sequences using the image of a micromirror array projected on a reaction site using a highly uniform beam of light...
7037642 Removing compounds from blood products with porous particles immobilized in a matrix  
Methods and devices are provided for reducing the concentration of low molecular weight compounds in a biological composition containing cells while substantially maintaining a desired biological...
7033820 Automated system for isolating and amplifying a target nucleic acid sequence  
An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples...
7033754 Decoding of array sensors with microspheres  
The invention relates to compositions and methods for decoding microsphere array sensors.
7030217 Solid phase native chemical ligation of unprotected or N-terminal cysteine protected peptides in aqueous solution  
The present invention provides methods, apparatus and kits for synthesizing assembled peptides and proteins on a solid phase with sequential ligation of three or more unprotected peptide segments...
7026124 Method and multiple reservoir apparatus for fabrication of biomolecular arrays  
Methods and apparatus for delivering a plurality of different biological materials onto discrete locations on a receiving surface, as for example to fabricate an array of different biological...
7022477 Detection of target substances utilizing biochemically specific binding reaction  
A composite material sheet which is composed of partitions two-dimensionally extending on a sheet plane to form on the sheet plane plural fine sections surrounded by the partitions and porous...
7022473 Substrates for immobilizing and amplifying DNA and DNA-immobilized chips  
Substrates for producing a DNA library are produced by immobilizing DNA onto a suitable substrate having excellent thermal conductivity. A surface of the substrate is chemically modified with a...
7022505 Apparatus and method for ultrasonic treatment of a liquid  
The present invention is an apparatus for ultrasonically treating a liquid to generate a product. The apparatus is capable of treating a continuously-flowing, or intermittently-flowing, liquid...
7014823 Biomolecular-based actuator  
This invention relates to actuators having biologically-based components, and methods of making and using the same. The actuator of the invention has a movable member that moves substantially...
7011945 Random array of micro-spheres for the analysis of nucleic acids  
A method of identifying nucleic acid samples comprising: providing a mircoarray including a substrate coated with a composition including a population of micro-spheres dispersed in a fluid...
7010432 Method and system for determining the acceptability of signal data collected from a prothrombin time test strip  
A method for determining the acceptability of signal data collected from a prothrombin time (PT) test strip includes collecting PT signal data from an assay area and control areas of the PT test...
7008769 Nanoscale molecular arrayer  
The present invention is a dedicated apparatus for the formation of array that includes one or more deposition domains comprised of one or more deposition materials. The present invention may...
7005259 Methods for array preparation using substrate rotation  
Methods are provided for the preparation of polymer arrays on wafers wherein the wafers are rotated between synthesis steps to provide more uniform results across the entire wafer.
7001572 Analyzing device with biochip  
The invention concerns a device for analyzing at least an analyte, comprising a container and a biochip defining together at least a section, attached to the container by a suitable adhesive. The...
6998236 Methods for detecting interaction between a test moiety and a plurality of target moieties  
This invention relates generally to the field of microarray technology. In particular, the invention provides an integrated microarray device, which device comprises a substrate comprising a...
6998274 Composite arrays utilizing microspheres  
The invention relates to compositions and methods for decoding microsphere array sensors.
6998230 Array fabrication with drop detection  
A drop deposition apparatus, and a method and computer program products using the drop deposition apparatus, for fabricating at least one addressable array of biopolymers on a substrate. The drop...
6994972 Porous substrates for DNA arrays  
A planar, rigid substrate made from a porous, inorganic material coated with cationic polymer molecules for attachment of an array of biomolecules, such as DNA, RNA, oligonucleotides, peptides,...
6989234 Method and apparatus for non-contact electrostatic actuation of droplets  
An apparatus for actuating a droplet comprises a first conductive layer, a second conductive layer, a conductive elongate element, and a voltage source. The first conductive layer comprises a...
6979576 Methods of use of one step immunochromatographic device for Streptococcus A antigen  
A method to determine the presence or absence of Streptococcus Group A antigen in a sample, comprising the following steps: extracting the antigen from the sample in an assay chamber with two or...
6977149 Biochemical reaction detection apparatus  
A biochemical reaction detection chip capable of controlling the temperature for biochemical reactions including hybridizations and its substrate. The function of the chip is performed by...
6977145 Method for carrying out a biochemical protocol in continuous flow in a microreactor  
Devices and methods for carrying out a chemical or biochemical protocol are disclosed. In one embodiment, the chemical or biochemical protocol is performed by cycling at least one thermal transfer...
6972184 Cell motility assay  
An electrooptical method is disclosed for quantifying the motility response of cells to external stimuli, wherein a target cell population (formed as a function of said response) is subsequently...
6965433 Optical biodiscs with reflective layers  
An optical biodisc has a substrate, a first reflective layer over the substrate, an opening in the first reflective layer for receiving an investigational feature, and a second reflective layer...
6964857 Measuring indigenous photosynthetic organisms to detect chemical warefare agents in water  
A method of testing water to detect the presence of a chemical or biological warfare agent is disclosed. The method is carried out by establishing control data by providing control water...
6962782 Method for producing addressed ligands matrixes on a support  
A method for fabricating matrices of addressed ligands on a carrier. In the method, an element is used such as a reservoir filled with ligand and containing an electrode to deposit and...