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7528952 Hand-held fluorescence polarimeter  
A small, portable, hand-sized apparatus for detecting microorganisms or chemicals in liquid samples by fluorescence polarization. The apparatus operates using a low power excitation light source,...
7527981 Bioweapon-detecting fibrous-network products and methods for making same  
Methods are disclosed for producing a bioweapon-sensitive fibrous-network product, wherein the subject products exhibit a color change in response to exposure to a biological agent (or portion...
7524464 Smart disposable plastic lab-on-a-chip for point-of-care testing  
Disclosed herein is a fully-integrated, disposable biochip for point-of-care testing of clinically relevant parameters. Specifically, in accordance with an embodiment of the present invention, the...
7521225 Nanotube structures having a surfactant bilayer inner wall coating  
Nanotubes and nanotube array structures comprise (a) a nanotube having an inner wall portion; and (b) a bilayer coating formed on the inner wall portions, with the bilayer coating comprised of...
7521179 Thermo-optical analysis system for biological reactions  
The invention relates to a reaction device, comprising a sample chamber matrix (1), comprising at least two reaction chambers (2) whose walls are permeable with respect to electromagnetic...
7510687 Simultaneous detection of different antibodies and antigens in clinical alimentary and environmental samples  
Method and device to simultaneously detect different antibodies and antigens via immunoenzimatic tests and ELISA (Enzyme Linked ImmunoSorbent Assay) constituted by small absorbent cylinders, on...
7507575 Multiplex fluorescence detection device having removable optical modules  
Techniques are described for the detection of multiple target species in real-time PCR (polymerase chain reaction). For example, a system comprises a data acquisition device and a detection device...
7507530 Nanoparticle complexes having a defined number of ligands  
A rapid method for the separation of nanoparticles having as few as one ligand attached thereto has been developed. The method relies on the size exclusion separation of a population of...
7498423 Carbon nanotube-nucleic acid complexes  
Nucleic acid molecules in a stabilized solution such as single stranded DNA and RNA were able to disperse high concentration of bundled carbon nanotubes into aqueous solution.
7497992 Detection of biochemical interactions on a biosensor using tunable filters and tunable lasers  
An apparatus and method for detection of peak wavelength values of colorimetric resonant optical biosensors using tunable filters and tunable lasers is provided. Biomolecular interactions may be...
7499806 Image processing in microsphere arrays  
Described herein are methods for registering analytical images comprising obtaining an image of an array, wherein the image depicts fiducials that can be used to register the sequential images of...
7497996 Liquid delivery apparatus and liquid delivery method  
A liquid delivery apparatus 1 has a rotary substrate 2. The substrate 2 formed with a fluid passage 8A for communicating a supply chamber 6A and target chamber 7A. An inlet end portion 13 at which...
7491496 Method for immobilizing nucleic acid and method for manufacturing biosensor using the same method  
A method is provided to enable high-density absorption when immobilizing nucleic acid probes onto a solid support surface by suppressing electrostatic repulsion among the nucleic acids. A nucleic...
7485471 Detection of enhanced multiplex signals by surface enhanced Raman spectroscopy  
Various methods of using Raman-active or SERS-active probe constructs to detect analytes in biological samples, such as the nucleic acid and/or protein-containing analytes in a body fluid are...
7482152 Methods and devices for microencapsulation of cells  
Devices for the microencapsulation of cells include a first chamber for containing a cell-solution suspension. A plate covers one end of the first chamber. The plate has a plurality of apertures....
7473547 Test piece, method of and apparatus for manufacturing the test piece and method of and system for reading the same  
A test piece for use in biological analysis of a sample is formed of a strip-like substrate and numbers of known specific binding agents which are different from each other and are arranged in a...
7465578 Nucleic acid sequencing by Raman monitoring of uptake of precursors during molecular replication  
The methods, compositions and apparatus disclosed herein are of use for nucleic acid sequence determination. The methods involve isolation of one or more nucleic acid template molecules and...
7466908 System for rapid nucleic acid amplification and detection  
A temperature cycling system (10, 110) is provided for repeatedly heating and cooling a reaction mixture (16). The system (10, 110) includes a first heater (27) and a second heater (28) each...
7462268 Particle/cell separation device and compositions  
A particle/cell separation device is described which is particularly adapted for neutrophil depletion from a preparation of whole blood or platelet-rich plasma. Also described are blood and...
7455971 Multiplex decoding of array sensors with microspheres  
The invention relates to compositions and methods for multiplex decoding of microsphere array sensors.
7455967 Device for analyzing chemical or biological samples  
The present invention relates to a method, and to a corresponding device, for analyzing chemical or biological samples in which chemical or biological samples and/or targets (probes) are applied...
7452669 Micro PCR device, method of amplifying nucleic acid and method of measuring concentration of PCR product using the same  
A micro PCR device comprising an amplification chamber is provided. The amplification chamber has an inner surface coated with a polycationic polymer or a polyanionic polymer and includes electrodes.
7449326 System for simple nucleic acid analysis  
A system for simple nucleic acid analysis is described in which the amplification space contains at least a part of the binding space. An additional improvement is achieved by the design of the...
7449327 System and method for dispensing dehydrated culture media powder  
An improved system and method for dispensing dehydrated culture media (DCM) powder into containers for preparation as a culture media. The manual and automated systems and methods operate to...
7445926 Fluid control structures in microfluidic devices  
Methods and apparatus for implementing microfluidic analysis devices are provided. A monolithic elastomer membrane associated with an integrated pneumatic manifold allows the placement and...
7442502 Biochip  
When the genetic analysis is performed by using a DNA microarray, the inspection accuracy is improved. A sample solution is supplied onto a base plate to prepare the DNA microarray comprising a...
7442499 Substrates comprising polynucleotide microarrays  
A method of determining the relative amounts of individual polynucleotides in a complex mixture of different-sequence polynucleotides is disclosed. The polynucleotides, after fluorescent labeling,...
7439055 Biomolecular detection device  
A device for detecting and measuring the concentration of biomolecules in solution, utilizing a conducting electrode in contact with a solution containing target biomolecules, with a film with...
7438856 Microfluidic devices and methods  
Embodiments of the invention are directed to microfluidic devices. In one embodiment, a microanalysis chip comprises a body having at least one transfer-separation channel with a channel bottom...
7427497 In vitro metabolic engineering on microscale devices  
Disclosed herein is a microfluidics device that can be used to prepare natural products and their analogs. The device comprises the enzymes of a biosynthetic pathway immobilized thereon and a...
7427417 Aromatherapy delivery system  
An aromatherapy delivery system for people and animals allows targeted placement of scents in close proximity to the olfactory system to provide the continuous, stimulating, relaxing, therapeutic...
7427513 Surface modification of metals for biomolecule detection using surface enhanced Raman scattering (SERS)  
The present invention is based on the discovery that the methods described herein for the production of metallic colloids result in colloids exhibiting increased signal enhancement and...
7425455 Biosensor, magnetic molecule measurement device  
A biosensor not requiring washing of an unbonded label molecular by analyzing an object to be measured such as an antigen, an antibody, a DNA, and an RNA through magnetic field sensing. The...
7425440 Culture flask  
A culture flask 10 comprises two or more internal chambers 18-21 defining a plurality of parallel surfaces of different sizes and means for fluid communication 24 between the chambers 18-20.
7422851 Correction for illumination non-uniformity during the synthesis of arrays of oligomers  
The present invention provides an apparatus and a method for the synthesis of arrays of oligomers that have tight illumination intensity requirement. The apparatus and the method contains a...
7422893 Apparatus for growing cells under variable hydrostatic pressures  
An apparatus for growing cells in a 2-D cell cassette having a matrix for cell growth under pressure comprising two side assemblies which include a frame with a rigid support that fits over the...
7422900 System and method for forming a connective tissue construct  
A system and method are provided for forming a connective tissue construct, such as a tendon construct, in vitro. A substrate is provided with at least two anchors secured thereto in spaced...
7419821 Apparatus and methods for analyte measurement and immunoassay  
The present invention relates to an apparatus for conducting a variety of assays for the determination of analytes in liquid samples, and relates to the methods for such assays. In particular, the...
H002223 Patterned, micrometer-sized antibody features  
A biosensor has a micrometer sized antibody substrate surface which may include patterned single or multiple antibody substrates. The substrate is capable of detecting multiple chemical species...
7415144 Cell observation device and cell observation method  
The cell observation device and method aims to easily study the correlation between initial states of cells and their reactions without using a synchronous culture method. For this purpose, the...
7410809 Particle or cell analyzer and method  
A particle analyzer in which tagged particles to be analyzed are drawn through a suspended capillary tube where a predetermined volume in the capillary tube is illuminated. The illumination...
7410791 Device containing cytophilic islands that adhere cells separated by cytophobic regions  
The invention provides a device for adhering cells in a specific and predetermined position, and associated methods. The device includes a plate defining a surface and a plurality of cytophilic...
7410763 Multiplex data collection and analysis in bioanalyte detection  
Method and device to collect multiplex data simultaneously in analyte detection and analyze the data by experimentally trained software (machine-learning) is disclosed. Various ways (magnetic...
7408640 Fluorescence polarization instruments and methods for detection of exposure to biological materials by fluorescence polarization immunoassay of saliva, oral or bodily fluids  
The inventive subject matter relates to a method for detecting the presence of a biological substance of interest in a test sample of saliva or oral fluid, comprising combining said test sample...
7405072 Acoustic radiation for ejecting and monitoring pathogenic fluids  
The invention relates to methods and devices that use focused radiation to handle and/or monitor pathogenic fluids. In particular, a method is provided for dispensing one or more droplets of a...
7405073 Point source biological agent detection system  
This invention is directed to a method and apparatus using polymerase chain reaction (PCR) technology for collecting air samples and identifying biological agents in the air sample. The apparatus...
7402422 Systems and methods for detecting and analyzing polymers  
A detection system and methods for improving the ability of the detection system to recognize labels that are disposed on a polymer. Embodiments of the invention include schemes for selecting...
7402425 Stress-based electrostatic monitoring of chemical reactions and binding  
Electrostatic capacitance measurements are used to detect chemical or biological analytes, or chemical interactions, with great sensitivity. A diaphragm is coated with a material capable of...
7399470 Sandwich immunoassay kits for detecting ciguatoxin CTX3C  
A sandwich immunoassay kit for detecting ciguatoxins based on a combination of two anti-ciguatoxin CTX3C monoclonal antibodies produced by hybridomas, 3D11 (deposited at IPOD, AIST under accession...
7398015 Apparatus for controlling fluid-heating using polymer disk  
Provided is an apparatus for controlling fluid-heating using a polymer disk, which includes: a pump for discharging fluid at a uniform flow rate; a fluid-heating module including a polymer disk to...