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7740747 Injection method for microfluidic chips  
A microchip for capillary electrophoresis is provided. The microchip comprises an injection channel and a separation channel configured to receive a sample through a sample well disposed on a...
7736889 Fluidic force discrimination  
This invention describes a method of using controlled fluidic forces to improve the performance of a biochemical binding assay where a target molecule is captured by specific molecular recognition...
7736888 Stage and platform for building a biochip and biochip  
A biochip, a platform which composes the biochip, and a stage which composes the platform. The biochip is for detecting analytes in a test sample. The platform comprises a stage. The stage of the...
7736890 Assay device and method  
An assay method is described, which comprises the steps of immobilizing a binding partner (e.g., an antigen or antibody) for an analyte to be detected (e.g., an antibody or antigen) on a portion...
7732140 Method for direct electrical detection of molecules and molecule-molecule interactions  
A method for direct electrical detection of proteins, peptides and the like, and their interactions includes an electrode arrangement, a current/voltage provider, and a circuit analyzer. The...
7734422 Method for evaluating DNA probes position on substrate  
An oligonucleotide array comprising an array of multiple oligonucleotides with different base sequences fixed onto known and separate positions on a support substrate, wherein said...
7732190 Modified two-component gelation systems, methods of use and methods of manufacture  
Compositions, methods of manufacture and methods of treatment for post-myocardial infarction are herein disclosed. In some embodiments, the composition includes at least two components. In one...
7727471 Rare cell detection using flat-panel imager and chemiluminescent or radioisotopic tags  
Disclosed is a system using a large area flat panel imager which is specifically adapted for rare cell detection methods. The system generally includes an imager having a sample receiving surface...
7723099 Immunoassay device with immuno-reference electrode  
An electrochemical immunosensor system with reduced interference, comprising: a first immunosensor that generates an electrochemical signal based on the formation of a sandwich between an...
7723045 Assays to predict atherosclerosis and dysfunctional high-density lipoprotein  
This invention provides novel assays for the detection of dysfunctional HDL. The assays are good diagnostics and/or prognostics for atherosclerosis or other pathologies characterized by an...
7722810 Apparatus and methods for automated handling and embedding of tissue samples  
An automated machine for handling and embedding tissue samples contained on microtome sectionable supports. The machine includes an input member configured to hold a plurality of the microtome...
7718129 Bioassay substrate and bioassay device and method  
A bioassay substrate (1) takes a flat-plate shape in which the principal surface similar to that of optical disc such as CD, etc. is circular. At the center of the substrate (1), there is formed a...
7713692 Nucleic-acid probe substrate, system for temperature control of the substrate, and gene detection method making use of the same  
A system used to detect and assay genes by using a nucleic-acid probe substrate is disclosed, which can be used in highly general-purpose genetic chips usable for various purposes, and has a...
7713703 Methods for monitoring the status of assays and immunoassays  
The invention relates in part to the use of independent assay controls (IACs) for the optical communication between an assay device and an instrument in monitoring and performing assays,...
7713749 Substrate for fabricating protein microarrays  
The present invention provides a substrate for protein microarrays, whereby compound A and GPTS are mixed for coating onto a solid support to form a layer, wherein said compound A is selected from...
7713708 Immunological assay system and method  
An immunological or immunohematological assay system is disclosed that includes a filter vessel capable of containing an assay sample, an incubator, a sample separation system, an image...
7713475 Lateral flow immunoassay device and method  
A lateral flow immunoassay test device is provided that includes a housing with an elongated slot for holding a test sample collector; an elongated holder member for securing at least one...
7708944 Ultra-sensitive, portable capillary sensor  
A portable, lightweight, rugged, easy-to-operate biosensor useful for rapidly detecting cells, viruses, antibodies, and other proteins. A capillary tube has a capture antibody immobilized on its...
7708945 Device and method for determining multiple analytes  
A device includes a planar optical waveguide, as part of a sensor platform, and, connected to the platform directly or by means of a sealing medium, a sealing layer. The sealing layer forms either...
7709247 Methods and systems for detecting biomolecular binding using terahertz radiation  
Provided herein are methods and systems for detecting biomolecular binding events using gigahertz or terahertz radiation. The methods and systems use low-energy spectroscopy to detect biomolecular...
7709243 Biochip and biomolecular detection system using the same  
The present invention is related to a biochip and a biomolecular detection system using the same. In particular, the biomolecular detection system is capable of detecting biological molecules...
7709195 Hybridization detecting unit relying on dielectrophoresis and sensor chip provided with the detecting unit  
A hybridization detecting unit which includes a reaction region in which hybridization takes place, a plurality of sites (e.g., the surface of electrodes) arranged in the reaction region to which...
7704699 Method for the characterization of the three-dimensional structure of proteins employing mass spectrometric analysis and computational feedback modeling  
A method for characterizing the three-dimensional surface structure of molecules, particularly proteins and protein complexes, employing mass spectrometric analysis, an electrospray ionization...
7704726 Active programmable matrix devices  
A system for performing molecular biological diagnosis, analysis and multistep and multiplex reactions utilizes a selfaddressable, selfassembling microelectronic system for actively carrying out...
7704730 Multiplexed assay methods  
The present invention is directed to methods for conducting multiplexed assays. The methods are particularly well suited for measuring a plurality of analytes that may be present in very different...
7700374 Device for capturing target substance  
It is intended to provide a target substance-capturing body comprising: a base consisting of a soluble protein; and two or more functional domains capable of binding to different target substances.
7700348 Biochip and the production method thereof  
The invention relates to a biochip comprising a substrate presenting a reflecting main surface and wherein the main surface presents localized sites that are made sensitive to fluorescence...
7700290 Method of manufacturing DNA chip  
A method of manufacturing a DNA (deoxyribonucleic acid) chip is provided. The DNA chip has a plurality of transistors formed on a substrate and an organic layer and a DNA probe sequentially...
7700276 Device, kit and method for pulsing biological samples with an agent and stabilising the sample so pulsed  
The present invention is related to a device, kit and method for pulsing a biological sample with a pulsing agent and subsequently stabilizing the biological sample so pulsed. The invention has...
7695956 Device for cell separation and analysis and method of using  
A microflow device for separating or isolating cells from a bodily fluid or other liquid sample uses a flow path where straight-line flow is interrupted by a pattern of transverse posts which are...
7695979 Biomolecule diagnostic devices  
A biosensor includes a substrate with a layer of receptive material disposed thereon overlying a layer containing a photo-reactive agent. The receptive material is specific for an analyte of...
7695910 Method for manufacturing hydrogel biochip by using star-like polyethylene glycol derivative having epoxy group  
A method for manufacturing a biochip and a biochip manufactured by the method are provided. In the biochip manufacturing method, a star-like polyethylene glycol derivative having an epoxy group at...
7695752 Target activated microtransfer  
A device for performing target activated transfer that includes a mounting surface for mounting a tissue sample; and a light source positioned to substantially uniformly irradiate both stained and...
7691623 Method for the fabrication of a “lab on chip” from photoresist material for medical diagnostic applications  
The present invention relates to a device for performing immuno assays (“biochip” or “lab on chip” respectively), a procedure for its fabrication and the use of the device for performing immuno...
7691625 Cell cultural vessel, production process thereof and cultured cell  
An object of the present invention is to provide a cell culture vessel which is simple in structure and easy to handle, and is capable of preventing damage to the cells when separated, promoting...
7687258 Direct electric biological agent detector  
A high sensitive detector detects and determines the presence of a very small amount of biological substances. The high sensitive detector comprises a sensor part, a sense amplifier, and...
7682816 Thin film coated microwell arrays and methods of using same  
This invention relates to microwell array compositions which are coated with one or more thin film coatings. The invention includes the process of fabricating and using thin film coated microwell...
7682798 Rapid classification of biological components  
A method is disclosed for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In an illustrative embodiment of the...
7678562 Addressable nanopores and micropores including methods for making and using same  
Featured are devices and systems embodying one or more electrically-addressable-solid-state nanopores useful for sensing and/or characterizing single macromolecules as well as sequencing DNA or...
7678564 Container with at least one electrode  
The invention relates to a container 20, 30 for receiving an aqueous solution, which is formed at least partially by an outer limit 21 forming an inner chamber 22, 32 for receiving the solution,...
7678546 Solid-state NMR method for screening cell membrane protein binding drug candidates  
Disclosed is a method for detection of ligand-cell membrane protein binding by solid state NMR spectroscopy. The method starts by forming a lipid bilayer inside nanopores of an anodic aluminum...
7678565 Flow cell array and the utilization thereof for multianalyte determination  
A one- or two-dimensional arrangement of flow cells is provided, as part of an array of sample compartments, with at least one inlet and outlet for each sample compartment, formed by a base plate...
7674581 Autonomous genosensor apparatus  
An autonomous genosensor apparatus and methods for use are provided for the field detection and analysis of ambient chemical, biochemical, biologic, biogenetic, and radiologic materials under...
7670765 Method of forming monolayers of phage-derived products and used thereof  
Methods and compositions for identifying and characterizing the affinity of one or more ligands of a peptide are provided. In particular, a “stripped phage ligand sensor device” (SPLSD) is...
7670774 Probe of human papillomavirus and DNA chip comprising the same  
Oligonucleotide probes for analyzing 40 types of HPV were synthesized, and DNA chips were produced by using the oligonucleotide probes. The synthesis of the oligonucleotide probes is based on...
7670832 System for fluorescence monitoring  
The present invention is directed to devices for performing PCR and monitoring the reaction of a sample comprising a nucleic acid and a fluorescent dye. Illustrative devices comprise a heat...
7670770 Nanochannel arrays and their preparation and use for high throughput macromolecular analysis  
Nanochannel arrays that enable high-throughput macromolecular analysis are disclosed. Also disclosed are methods of preparing nanochannel arrays and nanofluidic chips. Methods of analyzing...
7670831 Conductive carbon nanotubes dotted with metal and method for fabricating a biosensor using the same  
Conductive carbon nanotubes (CNTs) obtained by dotting carboxylated CNTs with metal nanocrystals by chemical functional groups, are described, as well as a method for fabricating a pattern or film...
7670772 Microfluidic chip for multiple bioassay and method of manufacturing the same  
Provided are a microfluidic chip for multiple bioassay and a method of manufacturing the same. The method includes: forming microfluidic channels by coupling a channel structure having grooves for...
7666614 Method of use of one step immunochromatographic device for Streptococcus A antigen  
A method to determine the presence or absence of Streptococcus Group A antigen in a sample, comprising the following steps: extracting the antigen from the sample in an assay chamber with two or...