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7906324 Apparatus and method for incubating cell cultures  
A portable, self-contained incubation apparatus has a cell container in which a cell culture can grow. The cell container resides on a base along with other components that maintain the...
7906343 Surface-enhanced lanthanide chelates  
A lanthanide chelate is linked to a noble metal substrate at a proximity wherein the substrate enhances a fluorescent emission of the lanthanide by at least 20-fold when the chelate is illuminated...
7902121 MHC-antigen arrays for detection and characterization of immune responses  
T cells are profiled with respect to their expression of antigen receptor. The cells are arrayed on a planar or three-dimensional substrate through binding to immobilized or partially diffused...
7897378 Method and device for purifying nucleic acids  
The invention concerns a method for isolating and purifying nucleic acids from a sample and a device that is suitable therefore.
7897375 Method and apparatus for collecting and acclimatizing anaerobic ammonium oxidizing bacteria, and denitrifying water  
A method for collecting bacterial cells includes feeding water containing ammonium and nitrite to an anaerobic ammonium oxidation vessel to denitrify ammonium and nitrite by anaerobic ammonium...
7892816 Electrochemical detection of substrates  
The present invention provides a method for detecting probe-target substrate binding. In particular, the present invention provides a method for detecting a surface bound target complex by...
7892854 Multianalyte molecular analysis using application-specific random particle arrays  
The present invention provides methods and apparatus for the application of a particle array in bioassay format to perform qualitative and/or quantitative molecular interaction analysis between...
7888106 Microarrays and method for running hybridization reaction for multiple samples on a single microarray  
The present invention provides a microarray for multiple sample analysis that does not require an alignment of well walls with corresponding probe sets. Methods for building and using such a...
7888074 Microchip matrix device for duplicating and characterizing nucleic acids  
The aim of the invention is to provide a device for duplicating and characterizing nucleic acids almost simultaneously and with a high sample throughput rate. The device consists of a chamber body...
7883899 Diagnostic devices  
The present invention relates to analytical methods, platforms, and devices for the rapid and efficient immunochromatic determination of one or more components in fluid samples. The devices are...
7879598 Multianalyte determination system and methods  
The invention relates to embodiments of an optical system for luminescence determination, comprising two or more excitation light sources, a sensor platform and an optical component with several...
7879594 Method and device for detecting biomolecules  
The present invention relates to a method for detecting a target biomolecule in a sample comprising a plurality of biomolecules, whereby the target biomolecule is provided with a tag, said tag...
7875426 DNA biochip and methods of use  
The subject invention concerns materials and methods for detecting nucleic acid sequences. One aspect of the invention concerns a silicon-based “biochip” comprising nucleic acid immobilized...
7871811 Method for eliminating crosstalk between waveguide grating-based biosensors located in a microplate and the resulting microplate  
The present invention includes several methods for modifying the current processes of manufacturing optical sensing microplates that use continuous waveguide films to reduce/eliminate crosstalk...
7871770 Light transmitted assay beads  
A micro bead having a digitally coded structure that is partially transmissive and opaque to light. The pattern of transmitted light is determined by to decode the bead. The coded bead may be...
7871810 Multiaxis focusing mechanism for microarray analysis  
Systems and methods for positioning a multi-featured biological array relative to a signal acquisition device. Detection of the array's positional deviation may be achieved by a calibration beam...
7867751 Plasmid DNA isolation  
The invention provides apparatus, reagents, and methods for rapidly isolating plasmid DNA from a bacterial alkaline lysate.
7867754 Microarrays for analyte detection  
Method and device for detection of analytes, particularly biohazards. A microarray containing immobilized sensing molecules captures complementary analytes on a redundant patterned substrate....
7863056 Coated metal surface on solid support for analyte detection by displacement  
A coated metal surface on a solid support, wherein the coating consists of a protein layer firmly attached to the metal surface, and said protein layer is coupled to linker molecules that are...
7863140 Methods of making a molecular detection chip having a metal oxide silicon field effect transistor on sidewalls of a micro-fluid channel  
A molecular detection chip including a metal oxide silicon-field effect transistor (MOSFET) on sidewalls of a micro-fluid channel and a molecular detection device including the molecular detection...
7863003 Apparatus for implementing non-destructive quality control of substrates and printed biological microarrays  
Apparatus implements non-destructive quality control of substrates and printed biological microarrays. A method and apparatus are provided for implementing quality control of gel-based microarrays...
7858321 Methods and apparatus for conducting multiple measurements on a sample  
Multiplexed test measurements are conducted using an assay module having a plurality of assay domains. In preferred embodiments, these measurements are conducted in assay modules having integrated...
7858307 Light transmitted assay beads  
A micro bead having a digitally coded structure that is partially transmissive and opaque to light. The pattern of transmitted light is determined by to decode the bead. The coded bead may be...
7858398 Optical biosensor  
The present invention relates to an optical biosensor comprising a porous matrix. In the specific case, reference is made to anodized porous alumina, on the surface of which the biological...
7858363 Plasmid DNA isolation  
Apparatus, reagents, and methods for isolating plasmid DNA from bacteria by alkaline lysis using a solid or immobilized P2 and/or P3 reagent in combination with a DNA-binding matrix.
7858364 Apparatus and method for polymer synthesis using arrays  
The invention concerns a polymer synthesis apparatus (20) for building a polymer chain including a head assembly (21) having an array of nozzles (22) with each nozzle coupled to a reservoir (23)...
7855068 Methods and kits for detecting a target cell  
The present invention concerns the identification of specific target cells in whole blood. The present invention discloses methods for detecting and optionally quantifying a target cell in...
7851206 Nucleic acid detection device  
A nucleic acid detection device includes a flow channel through which a solution containing a nucleic acid recognition body flows, probe electrodes having immobilized nucleic acid probes, and a...
7853407 System for improving antibiotic use in acute care hospitals  
The present invention provides systems and methods for improving the administration and usage of antibiotic/antimicrobial regimens. The method and system of the invention includes (a) establishing...
7850917 Particle agglutination in a tip  
An apparatus and a related method for performing particle agglutination reactions in a single, disposable probe tip are disclosed. The probe tip includes a sample cavity for sample acquisition, at...
7850985 Tissue augmentation devices and methods  
Tissue augmentation devices, as well as methods of manufacturing and using the same, are disclosed. In certain embodiments, a tissue augmentation device comprises an elongate tissue penetrating...
7851028 Method of combing an elongated molecule  
Elongated molecules are stretched across a substrate by controlled fluid flow.
7846684 Enzyme system comprising an enzyme bonded in a porous matrix  
A protein system is described in which a protein is bound within a matrix material that has pores that are sized to achieve excellent properties such as: activity, protein density, and stability....
7846389 High throughput screen  
The present invention relates to a structure comprising a biological membrane and a porous or perforated substrate, a biological membrane, a substrate, a high throughput screen, methods for...
7846715 Sample chamber volume reducer  
An apparatus includes a chamber insert capable of being received by a sample chamber of a conditioning system. The received chamber insert reduces the volume of the sample chamber and defines a...
7846393 Membrane filter for capturing circulating tumor cells  
The present invention provides a parylene-based membrane filter device for capturing of circulating tumor cells (CTC). The membrane filter has an array of holes having a predetermined geometric...
7846713 Calibrating microarrays  
An assay for measuring the amount of a first analyte in a sample, comprises the steps of: (i) contacting the sample with a device that comprises one or more first reaction sites which comprise a...
7846727 Substratum having a pattern of cell-culture controlling substance  
The present invention relates to a substrate for cell culture capable of controlling at least one function selected from adhesion, proliferation, differentiation, survival, maintenance of...
7846714 Synthesis of chemical tags  
A method for forming a biological chemical tag. At least one double stranded DNA molecule is provided. At least a portion of the at least one double stranded DNA molecule is denatured. At least...
7846391 Bioanalytical instrumentation using a light source subsystem  
The invention relates to a light source for irradiating molecules present in a detection volume with one or more selected wavelengths of light and directing the fluorescence, absorbance,...
7842498 Hydrophobic surface chip  
The invention provides a water-swellable hydrophobic hydrogel and analytical devices incorporating the hydrogel of the invention. Also provided are methods of using the hydrogel to prepare the...
7843562 Detection of biomolecules using porous biosensors and Raman spectroscopy  
The invention provides methods used to analyze the contents of a biological sample, such as blood serum, with cascade Raman sensing. A fluorescence producing nanoporous biosensor having probes...
7842499 Substrates, devices, and methods for cellular assays  
The present invention relates to the field of molecular diagnostics. In particular, the present invention provided improved substrates and methods of using liquid crystals and other...
7842249 Apparatus for vaccine development using ultrasound technology  
Method and device for the creation of vaccines using ultrasonic waves, comprised of an ultrasound generator and a transducer to produce ultrasonic waves, is disclosed. The transducer has a...
7842475 Stabilization of solid support assay reagents  
Reagents are disclosed for use in assays for analytes. The reagents are dry assay reagents that may be readily reconstituted for use in the assays. The dry assay reagents comprise a solid support...
7838226 Deoxyribonucleic acid measuring apparatus and method of measuring deoxyribonucleic acid  
With an insulated gate field effect transistor in which deoxyribonucleic acid (DNA) probes are immobilized on a gold electrode, extension reaction on the gold electrode is performed with DNA...
7837939 Rapid sample collection and analysis device and methods of use  
The present invention is directed to devices and methods for determining the presence of analyte in a fluid sample. The devices utilize a sample collection well, an expression plate for expressing...
7838280 Device for squeezing of biological mass of cultures  
A device for wringing a biological mass of cultures has a substantially vertical container having a bottom provided with a discharge opening, a rotor means located under the discharge opening and...
7829313 Identification and quantification of a plurality of biological (micro)organisms or their components  
Disclosed is a system and method conducting real-time PCR. Capture molecules of a specific design are immobilized on a solid support, and contacted with amplicons produced in one or more PCR...
7824900 DNA analyzing apparatus, DNA sensor, and analyzing method  
A DNA analyzing apparatus includes a bath containing an electrophoresis medium. A plurality of probe electrodes are arranged in the bath. A plurality of spots each composed of probe DNA fragments...