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6291202 |
Disc assay device with inoculation pad and methods of use
An assay device for detection and enumeration of microorganisms. The device includes absorbent discs on a substrate, an inoculation vehicle to inoculate the discs with sample and an optional...
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6291200 |
Enzyme-containing polymeric sensors
A sensor for detecting the presence of at least one analyte includes at least one enzyme that is selected to either (i) catalyze a reaction of the analyte to chemically convert the analyte to a...
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6280967 |
Cell flow apparatus and method for real-time of cellular responses
An apparatus and method for real-time measurement of a cellular response of a test compound or series of test compounds (303) on a flowing suspension of cells (349), in which a homogeneous...
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6274373 |
Gene sequencer and methods
A gene sequencer, bio-compact disk and sample preparation methodology is described. Constant length oligonucleotides are prepared and, in conjunction with the bio-compact disk and apparatus...
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6274090 |
Apparatus and method of preparation of stable, long term thrombin from plasma and thrombin formed thereby
A sterile method for preparing stable thrombin component from a single donor's plasma in which the thrombin component is harvested simultaneously from the clotting and adhesive proteins component...
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6268147 |
Nucleic acid analysis using sequence-targeted tandem hybridization
The disclosed invention provides a novel method for analyzing genomic DNA and expressed sequences using auxiliary oligonucleotides, preannealed to the single-stranded target nucleic acid to form a...
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6268166 |
Method of quantitative assay for 1,5-anhydroglucitol
There is provided an enzymatic method of rapid quantitative assay for 1,5-anhydroglucitol which is also applicable to an automated analysis device. The enzymatic method of quantitative assay for...
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6265148 |
Blood control and system for erythrocyte sedimentation measurement
A control and system for blood testing, including a control having morphologically fixed and stabilized blood cells that have been added to a diluent. The control and system can be used...
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6261771 |
Method and apparatus for detection of multiple nucleic acid sequences and multiple antigens
A method and apparatus for detection of multiple target nucleic acids and/or antigens such as hormones, antibodies, or nerve agents in a sample, involves presenting the sample to a plurality of...
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6254827 |
Methods for fabricating multi-component devices for molecular biological analysis and diagnostics
A method for manufacturing a multicomponent flip-chip device is disclosed. The device includes a chip disposed adjacent to a substrate, the substrate including a via therethrough. The device is...
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6255061 |
Analytical element for the analysis of whole blood
An analytical element for quantitative analysis of glucose, cholesterol, or lactic acid in whole blood, composed of a porous layer which has a void volume of 30 to 80% and containing peroxidase, a...
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6248529 |
Method of chemically assembling nano-scale devices
The present invention provides nano-scale devices, including electronic circuits, using DNA molecules as a support structure. DNA binding proteins are used to mask regions of the DNA as a material,...
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6242239 |
Process for separating HIV from a fluid
A process for separating HIV from a fluid is described, in which the HIV is bound to a C1 esterase inhibitor immobilized on a support material. The process can be carried out both for the...
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6238908 |
Apparatus and method for maintaining and growth biological cells
An apparatus and related method are disclosed, for receiving, maintaining and growing biological cells ex vivo within a portable cassette, without exposing the cells to the external environment....
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6238879 |
Microbiological testing apparatus and method
An apparatus for carrying out a microbiological assay comprises a holder for holding an agar diffusion plate in operative proximity to a sensing system having one or more sensing devices, which in...
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6235251 |
System and method for treating cells using electromagnetic-based radiation
A device for treating cells is disclosed. The device includes a plurality of permanent magnets arranged in a side-by-side relationship with the magnetic north pole and the magnetic south pole of...
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6232091 |
Electrooptical apparatus and method for monitoring cell growth in microbiological culture
The present invention describes an electrooptical apparatus and method for monitoring cell growth in microbiological culture. The apparatus comprises an electrooptical cell filled up with a cell...
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6228635 |
Portable cell growth cassette for use in maintaining and growing biological cells
A portable cassette is disclosed, for receiving, maintaining and growing biological cells ex vivo, without exposing the cells to the external environment. The portable cassette is used in...
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6225107 |
Tissue specimen carrier
A carrier and method of using to orient and maintain an excised tissue sample in an orientation sufficient to determine its position in a body. The carrier permits radiological and pathological...
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6225043 |
Separation and analysis
A separation method, a method for detection, a sensor, and a test-kit find application in immunological detection. The separation method provides for separation of a primary species which...
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6225059 |
Advanced active electronic devices including collection electrodes for molecular biological analysis and diagnostics
Methods of manufacture and devices for performing active biological operations utilize various structures to advantageously collect and provide charged biological materials to an array of...
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6225055 |
Apparatus for the parallel alignment of macromolecules, and use thereof
The present invention relates to an apparatus for the parallel alignment of macromolecules on the surface S of a solid support by displacement of a meniscus formed by the triple interface surface...
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6221666 |
Method and apparatus for cytoplasmic loading using an impact-mediated procedure
The present invention is directed to the method and apparatus for the cytoplasmic loading of macromolecules into living cells by an impact-mediated procedure that impacts the cells with a...
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6207445 |
Filtration and extraction device and method of using the same
The present invention involves a simple, disposable, manual filtration and extraction device and method of use that provides a sample directly to an analytical method. The device is capable of...
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6207405 |
Pilot drain system for rapid biofilm formation
This invention provides a methodology for rapid biofilm formation in a pilot drain system. In a typical embodiment, aqueous nutrient medium and an inoculum comprising both Sphaerotilus natans and...
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6197538 |
Method of establishing the presence of specific substances in milk and an implement for applying same
A method and apparatus for ascertaining and measuring the quality of milk by analyzing reflected or absorbed colors or both with which the milk is irradiated. The milk is thus irradiated with three...
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6190858 |
Detection of conditions by analysis of gases or vapors
The invention discloses a method for monitoring at least one condition in a patient comprising the steps of (a) obtaining samples from the patient over a period of time; (b) flowing the samples, or...
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6190878 |
Device and methods for determination of analyte in a solution
Method and assay devices for the detection of the presence or amount of biological material, analyte(s), or microorganism(s) in a sample. The method includes the steps of liquefying the sample (if...
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6190609 |
Methods and apparatus for inactivating contaminants in biological fluid
Apparatus and methods for treating a biological fluid with light and for inactivating contaminants in biological fluid. The biological fluid is contacted with a light source providing a high...
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6187544 |
Methods for rapid cloning for full length cDNAs using a pooling strategy
The present invention provides a method for high throughput cloning of full length cDNA sequences using a pooling strategy. This method uses a plurality of clone arrays prepared from cDNA libraries...
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6187537 |
Process and apparatus for forming a dry DNA transfer film, a transfer film product formed thereby and an analyzing process using the same
Pivotable jigs or tables facilitate inversion or reciprocation of one or more well plates relative to a dry DNA transfer sheet to effect deposit of DNA gene solution as spaced spots on the surface...
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6183982 |
Fermentation bung device and method
A fermentation device and a method for making a substance using the device are provided. The fermentation bung may have an outer plug that includes a central inner annular hole and a one or more...
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6180335 |
Apparatus for detecting contamination in food products
The present invention is a disposable element for assaying food samples and a method for using the element. The disposable element includes a container having first, second, and third ports, a...
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6180394 |
Method of carrying out a treatment in the presence of a centrifugal force and an apparatus therefor
The invention relates to a method and an apparatus for carrying out a treatment in the presence of centrifugal force. The treatment may be a physical or a chemical treatment. For this purpose the...
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6165739 |
Multiple simultaneous testing media
A stationary testing media device made of a glass or plastic plate and conveniently a microscope slide, wherein multiple simultaneous tests are conducted on a single multifurcated testing sample....
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6165740 |
Method and device for flow-cytometric microorganism analysis
To reduce the effects of the contaminants in the measurement of microorganisms and the reduction of the time necessary for the measurement. Measurement is performed of the microorganism prior to...
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6156501 |
Arrays of modified nucleic acid probes and methods of use
Oligonucleotide analogue arrays attached to solid substrates and methods related to the use thereof are provided. The oligonucleotide analogues hybridize to nucleic acids with either higher or...
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6153400 |
Device and method for microbial antibiotic susceptibility testing
A method and apparatus for performing microbial antibiotic susceptibility testing include disposable, multi-chambered susceptibility plates and an automated plate handler and image acquisition and...
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6150166 |
System for propagating in vitro tissue cultures of a plant species
A system for stimulating rooting of an in vitro tissue culture of a plant species includes a container supporting a composite comprising a first and second medium. The first medium is conducive to...
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6146843 |
Method and apparatus for the use of sentinel microorganism
A sentinel chamber for containing microorganisms in a matrix, and methods for the use of the chamber in studying organisms in the field. The matrix is typically the same material as that within...
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6143515 |
Process for evaluating microbial-degradability of organic matters and apparatus therefor
The disclosed in an invention directed to carrying out accurate and easy evaluation of microbial-degradability of organic matters objectively. To carry out a method for evaluating...
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6143512 |
Cap-pap test
The CAP-PAP Test is a double-staining, single-slide microscopic method. An in vitro diagnostic medical device for manual and automatic staining and interpreting of the Pap smear for cervical cancer...
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6140069 |
Method for determining antibiotic sensitivity of bacteria
A method and apparatus for determining the minimum inhibitory concentration of an antibiotic for a target microorganism is provided. The method includes the steps of: (a) providing a microorganism...
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6140070 |
Sample collecting method and apparatus
The present invention is directed to methods and apparatus for collecting and pooling the contents of a multiple number of individual sample containers, the apparatus comprising an autoclavable...
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6140048 |
System for distinguishing fluorescent molecule groups by time resolved fluorescence measurement
System and method for distinguishing at least two types of molecule groups that are bound to analyte molecules and which have different fluorescent characteristics. The system performs...
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6136960 |
Method for evaluation of the ratio of amounts of biomolecules or their sub-populations in a mixture
The present invention is directed to a method of determining the ratio of the concentration or amounts of two or more chemical compounds and/or biopolymers, or of the relative amounts of...
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6123954 |
Apparatus and method for inhibiting microbial growth in an aqueous medium
A method of inhibiting microbial growth in wash water contained in a photoprocessing system. The method comprises placing in the wash water an apparatus comprising a pump with an attached permeable...
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6123902 |
Device for highly sensitive magnetic detection of analytes
An apparatus for the qualitative and/or quantitative measurement of analytes, in particular in biological samples by means of receptor ligand binding and having a magnetizing device for the...
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6124111 |
Method and an arrangement for measuring the amount/activity of catalase before or in connection with bleaching of preferably cellulose fibres included in a pulp suspension
The invention relates to a method and a device for measuring the amount/activity of the enzyme catalase before or in connection with bleaching of cellulose fibers preferably in a pulp suspension...
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6121011 |
Methods for applying a reagent to an analytical test device
This invention provides methods and apparatus for applying a reagent to an analytical test device. The methods and apparatus employ a nozzle and a flexible restrictor to accurate control the amount...
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