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8349582 High-efficiency viable sampler for ultrafine bioaerosols  
Exemplary embodiments provide bioaerosol detection systems and methods for detecting bioaerosols. In one embodiment, the bioaerosol detection system can include a humidifier to increase the...
8349618 Diagnostic devices  
The present invention relates to analytical methods, platforms, and devices for the rapid and efficient immunochromatic determination of one or more components in fluid samples.
8343855 Nanostructured device  
The invention concerns a nanostructured device (100) comprising a substrate (101), an intermediate layer (102), a zone (103) consisting of multiple three-dimensional structured sites (104) made of...
8343740 Micro-organ device  
A method for fabricating a micro-organ device comprises providing a microscale support having one or more microfluidic channels and one or more micro-chambers for housing a micro-organ and...
8343778 Microfluidic microarray assemblies and methods of manufacturing and using  
The invention encompasses microfluidic microarray assemblies (MMA) and subassemblies and methods for their manufacture and use. In one embodiment, first and second channel plates are provided and...
8343754 Annealing curve analysis in PCR  
The present invention is directed to devices for performing PCR and monitoring the reaction of a sample comprising a nucleic acid and a fluorescent dye. Illustrative devices comprise a heat...
8338097 Method and apparatus for combined electrochemical synthesis and detection of analytes  
Described are devices and methods for detecting binding on an electrode surface. In addition, devices and methods for electrochemically synthesizing polymers and devices and methods for...
8338165 Nanoparticulate cell culture surface  
A cell culture article including a substrate having nanoparticles on the substrate surface, the nanoparticle including: a polymer of formula (I) where (x), (y), (z), R, R′, R″, S, W, and X, are as...
8338191 Centrifugal device and method for performing binding assays  
The invention relates to a device for performing binding assays. In particular, the invention relates to a centrifugal device for performing such assays. The invention also relates to a method of...
8338164 Systems and methods for delivery of a therapeutic agent  
Methods and apparatus are provided for applying an fragment of a neurotoxin such as the active light chain (LC) of the botulinum toxin (BoNT), such as one of the serotype A, B, C, D, E, F or G...
8338166 Sorting, amplification, detection, and identification of nucleic acid subsequences in a complex mixture  
A system for identifying all of the known and unknown pathogenic or non-pathogenic organisms in a sample. A droplet generator creates droplets from the sample. The droplets constitute...
8329451 Cell electrophysiological sensor and method for manufacturing the same  
In a cell electrophysiological sensor having a thin plate with a through hole, a support plate with a through hole and a container plate with a through hole stuck to an upper portion of this...
8329401 Enzyme-catalyzed metal deposition for the enhanced detection of analytes of interest  
The invention is directed to enhanced methods for detecting an analyte of interest in situ, by immunoassay, or by hybridization comprising binding an enzyme-labeled conjugate molecule to an...
8323892 Hybridization method and apparatus  
A target nucleic acid contained in a sample solution is hybridized with a probe nucleic acid capable of binding specifically to the target nucleic acid and immobilized on a substrate. The process...
8323986 Molecular assembly on a substrate  
The present invention relates to a molecular assembly on a substrate usable for studying and/or performing biological interactions and/or reactions The invention further relates to an in vitro...
8323953 Detection device for detecting biological microparticles such as bacteria, viruses, spores, pollen or biological toxins, and detection method  
A device for the detection of micro particles that can be marked by probes or antibodies capable of being detected by radiation has a filter, a supply system, and a detection system. Fluid to be...
8318919 Nucleic acid hybridization methods  
Disclosed herein are methods of destabilizing double-stranded nucleic acid hybridization using an enzyme comprising DNA N-glycosylase activity. Also disclosed herein is the detection of a...
8317728 Method of using flocked swab for collecting biological specimens  
The present invention relates to a swab for collecting biological specimens of the type consisting of a rod terminating in a tip covered with fiber with hydrophilic properties to allow absorption...
8313699 Sterilization testing device  
The invention relates to a sterilization testing device comprised of a housing with a test chamber, an indicator placed therein, and with a supply for supplying the sterilization medium. According...
8313906 Methods and systems for microfluidic DNA sample preparation  
The present invention relates to methods and systems for microfluidic DNA sample preparation. More specifically, embodiments of the present invention relate to methods and systems for the...
8313940 Self-addressable self-assembling microelectronic systems and devices for molecular biological analysis and diagnostics  
A self-addressable, self-assembling microelectronic device is designed and fabricated to actively carry out and control multi-step and multiplex molecular biological reactions in microscopic...
8313710 Multilayered optical sensing patch and retaining plug therefor  
A multilayered optical sensing patch, for the measurement of conditions, such as pH, oxygen level, etc, within containers, is provided. The multilayered optical sensing patch of the present...
8313904 Biological analysis arrangement and approach therefor  
Characteristics of a chemical or biological sample are detected using an approach involving light detection. According to an example embodiment of the present invention, an assaying arrangement...
8313907 Charge perturbation detection system for DNA and other molecules  
Methods and apparatus for direct detection of chemical reactions are provided. In a preferred embodiment, electric charge perturbations of the local environment during enzyme-catalyzed reactions...
8314052 Methods for simultaneous generation of functional ligands  
The present invention relates to methods for generating functional biomolecules. In one exemplary aspect of the invention, generation of functional biomolecules may be performed against multiple...
8309364 Method of performing an immunoassay in blood  
An electrochemical immunosensor system with reduced interference, comprising: a first immunosensor that generates an electrochemical signal based on the formation of a sandwich between an...
8309345 Method for detecting an antigen  
Provided is a method for detecting an antigen without use of a labeled-antibody. A support having an antibody and a multi-copper oxidase CueO immobilized thereon is brought into contact with a...
8309342 Apparatus and methods for cell isolation  
A unitary apparatus for isolating cells from adipose tissue including a lipid separation processor with a dispersing head equipped with a plurality of ports and a digestion chamber for...
8304245 Microfluidic flow lysometer device, system and method  
The invention provides a device, system and method that enables a microfluidic flow lysometer cell analyzer. Using a population of suspended living cells. cell surface molecule detection reagents,...
8304185 Methods and systems for DNA isolation on a microfluidic device  
The present invention relates to methods and systems for the isolation of DNA on a microfluidic device and the subsequent analysis of the DNA on the microfluidic device. More specifically,...
8304188 Barriers for facilitating biological reactions  
The present invention relates to systems, devices, and methods for performing biological reactions. In particular, the present invention relates to the use of lipophilic, water immiscible, or...
8304186 Reactor for performing biochemical processes  
A reactor (1) for performing biochemical processes, particularly for extraction, purification, enrichment, sedimentation, comprising a container which is provided with at least one mouth (2) which...
8304230 Microfluidic device for cell separation and uses thereof  
The invention features methods for separating cells from a sample (e.g., separating fetal red blood cells from maternal blood). The method begins with the introduction of a sample including cells...
8298606 Methods and compositions for stabilizing the myocardium  
The present invention provides materials and methods that can serve as a prosthetic and/or, for tissue engineer applications, as a supporting matrix in the stabilization of the myocardium.
8298763 Automated high-throughput flow-through real-time diagnostic system  
An automated real-time flow-through system capable of processing multiple samples in an asynchronous, simultaneous, and parallel fashion for nucleic acid extraction and purification, followed by...
8298809 Method of making a hardened elongate structure from mycelium  
A method of making a hardened elongate structure, including growing a live mycelium mat having branching hyphae. The live mycelium mat is layered to form a multi-layered structure. The hyphae are...
8299227 Method of immobilizing and stretching a nucleic acid on a substrate  
The present invention relates to a method of immobilizing and stretching a nucleic acid on a silicon substrate, to nucleic acids and substrates prepared according to this method, to uses of the...
8293519 Microarray devices having controllable reaction volume  
This invention relates generally to the field of microarray chips and uses thereof. In particular, the invention provides a microarray reaction device that can be used in assaying the interaction...
8288152 Semiconductor nanocrystal probes for biological applications and process for making and using such probes  
A semiconductor nanocrystal compound and probe are described. The compound is capable of linking to one or more affinity molecules. The compound comprises (1) one or more semiconductor...
8288155 Biomolecular attachment sites on microelectronic arrays and methods thereof  
Methods of addressing a biomolecule to a selectively addressable electrode are described. A permeation layer overlying a plurality of selectively addressable electrodes is provided. The permeation...
8288167 Chemiluminescence sensor array  
Embodiments of the invention relate to integrated chemiluminescence devices and methods for monitoring molecular binding utilizing these devices and methods. These devices and methods can be used,...
8288151 Biochemical reaction cassette  
A biochemical reaction cassette is designed to uniformize the flow of liquid in the reaction chamber by using a simple additional arrangement. A member for reducing the cross sectional area of the...
8288153 Semiconductor nanocrystal probes for biological applications and process for making and using such probes  
A semiconductor nanocrystal compound and probe are described. The compound is capable of linking to one or more affinity molecules. The compound comprises (1) one or more semiconductor...
8287913 Method and apparatus for extraction of protein material from arthropod glands and a membrane formed therefrom  
An apparatus and method for the extraction of material from glands of arthropods. The apparatus comprises a container in which at least part of the glands are placed and a buffer solution at least...
8287895 Three-dimensional biological scaffold compromising polymer waveguides  
A three-dimensional biological scaffold. The scaffold includes at least three sets of polymer waveguides extending along at least three respective directions. The at least three sets of polymer...
8282896 Devices and methods for holding microfluidic devices  
Carriers or holders for holding microfluidic devices are provided. Some of the carriers that are provided include a hydration control device and/or a source of controlled fluid pressure to...
8283185 Magnetically susceptible particles and apparatuses for mixing the same  
The present invention includes a magnetically susceptible polymer component, a method of making the same, and apparatuses and systems for mixing, separating or localizing a magnetically...
8278097 Method for forming embryoid bodies  
The invention relates to a vessel for embryoid formation used for forming embryoid bodies from ES cells easily without complicated technique, and to a method for forming embryoid bodies easily and...
8278034 Methods of making frozen tissue microarrays  
The invention provides microarrays comprising a plurality of frozen tissues and/or cell samples and methods of preparing and using the same. By using frozen samples, the microarrays provide...
8273310 Centrifugal force-based microfluidic device for nucleic acid extraction and microfluidic system including the microfluidic device  
A centrifugal force-based microfluidic device for nucleic acid extraction and a microfluidic system are provided. The microfluidic device includes a body of revolution; a microfluidic structure...