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8133718 |
Analytical strip and detecting method using the same
An analytical strip and a detecting method using the analytical strip are provided. The analytical strip includes a substrate having a channel thereon. The channel has a first region, a second...
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8129136 |
Kit for performing an assay
The present invention relates to a kit for performing an assay. The kit comprises luminol, an oxidant, an electron mediator and a hypernucleophilic acylation catalyst.
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8101374 |
Oxidative chromogenic compound or salt thereof and production method thereof, and reagent composition and test instrument using the same
It is an object of the present invention to provide a means for measuring a concentration of various components rapidly with high accuracy and high sensitivity. The present invention is to provide...
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8080385 |
Crosslinked adduct of polyaniline and polymer acid containing redox enzyme for electrochemical sensor
A polymer matrix that may coated on an electrode is created by co-crosslinking (1) an adduct of a polyaniline formed by templated oxidative polymerization on a polymer acid; (2) a water-soluble...
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8080423 |
Reagent containing protease reaction promoter and/or colorant stabilizer
Stabilizers for colorants used for detection of enzymatic reactions, having a cyclodextrin and a catalase; reagents including stabilizers; and methods of use of such stabilizers and reagents.
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8067188 |
Analyte detection
The present invention relates to analyte detection test systems, including test systems for the oral detection of analytes in saliva. The present invention also provides compositions and methods...
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8048642 |
Heme choline esters and uses thereof
Methods of activating an apo-peroxidase are provided. The methods include the steps of providing a solution comprising an apo-peroxidase and a heme choline ester, hydrolyzing the heme choline ester...
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8021855 |
Method of decomposing protein with sulfonic acid compound
A method of assaying a glycated protein in a sample with the use of redox reaction, in which highly reliable measurement can be obtained. A sample containing a glycated protein is treated with...
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8012761 |
Detection of formaldehyde in urine samples
A method for rapidly detecting the presence of formaldehyde in a urine sample (e.g., urine or a urinary material associated therewith, such as headspace gas located associated with urine) is...
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8007998 |
Polymerized conjugates for biological applications
Polymerized conjugates of at least two proteins that have increased sensitivity for detecting proteins in biological assays such as gels and blots, and methods of preparing the conjugates, and a...
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8008085 |
Method of measuring HbA1c
A method of measuring HbA1c is provided that, even with a whole blood sample after storage, measurement accuracy substantially equal to a whole blood sample right after collection can be...
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8003343 |
Method for determining diamine oxidase
Disclosed is a method for determining histaminase (DAO; EC 1.4.3.6) activity in a sample. Said method comprises the following steps: an aqueous solution is supplied which contains a predefined...
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7998698 |
Method for predicting susceptibility to radiation pneumonitis
Provided is a method for determining whether an individual is likely to be susceptible to radiation pneumonitis from radiation therapy and for developing a treatment based on the determination of...
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7968290 |
Method of detecting gene
A method of detecting a gene including immobilizing a primer for DNA elongation onto an insoluble carrier having on the surface thereof a polymer substance containing a first unit having a...
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7964370 |
Analytical strip and detecting method using the same
An analytical strip and a detecting method using the analytical strip are provided. The analytical strip includes a substrate having a channel thereon. The channel has a first region, a second...
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7915004 |
Monoclonal antibodies, hybridomas, improved method for determining the protein PTX3 and kit for said determination
Method for determining the level of PTX3 protein in a sample of a biological fluid; hybridoma capable of producing a rat anti-PTX3 monoclonal antibody where said hybridoma is selected from the...
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7892781 |
Detecting a target using a composite probe comprising a directing agent, a metal nanoparticle and an enzyme
A test agent includes a composite probe having at least one nanoparticle having multiple metal atoms, a directing agent, and an enzyme. The directing agent attaches the probe to a target in a test...
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7820402 |
Immunoassay element
The immunoassay element for quantitatively analyzing an antigen by determining the change in enzymatic activity of an enzyme-labelled antigen or antibody caused by an immunological reaction. The...
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7811779 |
Method of multiquantification for cholesterol of low-density lipoprotein
Provided is a method of stabilizing a reagent that allows simultaneous quantification of LDL cholesterol and total cholesterol by a single measurement by suppressing spontaneous color development...
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7803573 |
Method for increasing light emission from a chemiluminescent reaction
Method for increasing the emission of light from a chemiluminescent reaction including luminol, a peroxidase enzyme, an oxidant and a mediator of electrons through the use of a hypernucleophilic...
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7780950 |
Systemic marker for monitoring anti-inflammatory and antioxidant actions of therapeutic agents
A diagnostic method of monitoring anti-inflammatory and/or antioxidant actions of therapeutic agents comprises determining the level of at least one systemic marker indicative of inflammation or...
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7781182 |
Ubiquitin ligase assay
The invention relates to assays for measuring ubiquitin ligase activity and for identifying modulators of ubiquitin ligase enzymes.
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7776563 |
Methods for identifying agents for treating cardiovascular disease using inhibition of myeloperoxidase binding
The present invention provides methods and agents for treating subjects who have or are at risk of developing or having cardiovascular disease. Such agents inhibit binding of myeloperoxidase (MPO)...
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7772007 |
Assay device for direct measurement of LDL cholesterol
An assay device and method for measuring the concentration of LDL-associated cholesterol in a blood-fluid sample are described. The method employs selective precipitation of VLDL and chylomicrons...
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7700305 |
Analyte detection
The present invention relates to analyte detection test systems, including test systems for the oral detection of analytes in saliva. The present invention also provides compositions and methods...
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7687244 |
Chromogenic composition for detecting spilled blood and associated methods
A chromogenic composition for detecting spilled blood includes a mixture of an acidified aqueous solution containing reduced FD&C Blue #1 and hydrogen peroxide. The chromogenic composition has a...
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7682839 |
Methods using novel chemiluminescent labels
Methods using chemiluminescent label compounds and chemiluminescent labeled conjugates are provided. The compounds comprise an acridan ring bearing an exocyclic ketene dithioacetal group and...
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7655427 |
Immunogenic proteins of Leptospira
The invention provides novel immunogenic proteins LigA and LigB from Leptospira for use in the development of effective vaccines and antibodies, as well as improved diagnostic methods and kits.
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7582420 |
Multiplex nucleic acid reactions
The invention is directed to a variety of multiplexing methods used to amplify and/or genotype a variety of samples simultaneously.
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7575884 |
Test piece for measuring high-density lipoprotein (HDL) cholesterol
The present invention relates to a test piece having a simple structure, by which HDL cholesterol can be measured easily using a small amount of specimen. A reagent layer (2) is formed on a support...
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7534580 |
PSP94 diagnostic reagents and assays
In the serum, PSP94 occurs as a free form or is associated with a carrier protein. PSP94 in its bound form has been quantified in the blood of prostate cancer patients and these measurements have...
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7527939 |
Polyclonal-monoclonal ELISA assay for detecting N-terminus proBNP
A specific and sensitive in vitro ELISA assay and diagnostic test kit is disclosed for determining levels of NT-proBNP protein in a variety of bodily fluids, non-limiting examples of which are...
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7524642 |
Assays for identifying ubiquitin agents and for identifying agents that modify the activity of ubiquitin agents
Provided are methods and compositions for assaying for ubiquitin agents that are enzymatic components of ubiquitin-mediated proteolysis and, more particularly, methods and compositions for assaying...
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7521200 |
Method for non-invasive rinse diagnosis and monitoring of periodontal diseases using colourimetric reagents
An assay test kit is used in a mouth rinse sample collection procedure involving collecting a mouth rinse sample from a patient. A neutrophil reactant diagnostic reagent is delivered to the rinse...
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7459286 |
Assessing the risk of a major adverse cardiac event in patients with chest pain
Methods for characterizing the near term risk of experiencing a major adverse cardiac event in a patient presenting with chest pain are provided. In one embodiment the method comprises determining...
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7432073 |
Method for detecting guaiacol producing bacteria
The present invention relates to a method capable of detecting proliferative bacteria in food and beverage, particularly acid or neutral beverage at low cost within a short time, a detection kit...
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7422734 |
Methods of producing lignin peroxidase and its use in skin and hair lightening
Methods of producing lignin peroxidase are provided. Also provided are methods and cosmetic compositions suitable for skin and hair lightening as well as kits and an article-of manufacturing...
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7419657 |
Treatment of atherosclerotic disorders
The present invention relates to the identification of lipid oxidizing abzymes as a key pathogenic factor in atherosclerotic disorders. Methods and means for the reduction of abzyme mediated lipid...
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7407743 |
Kit and method of screening wilson's disease
The present invention relates to a method for measuring a ceruloplasmin concentration, and more particularly, to a method for measuring a ceruloplasmin in a blood spot based on a standard...
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7390670 |
Signalling compounds and methods for detecting hydrogen peroxide
Methods and compound useful for detecting a source of hydrogen peroxide are disclosed wherein a signalling compound of the formula: is reacted with peroxide. Sig is a non-polymeric organic group, B...
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7354732 |
Method of assay with sulfonic acid compound and nitro compound
A method for measuring an analyte in a sample by using a redox reaction is provided, which gives values with excellent reliability. Prior to the redox reaction, at least one of a sulfonic acid...
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7354733 |
Method for sorting and separating living cells
We disclose methods of sorting or separating mixtures of living cells (e.g., eukaryotic, prokaryotic, mammalian, pathogenic, bacterial, viral, etc.). We perform our methods by activating...
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7348135 |
Assay for detecting changes in mitochondrial membrane permeability and method of using same
An assay for assessing the permeability of mitochondrial membranes is provided. The assay is based on enzymatic reactions that produce a detectable signal in the presence of intra-mitochondrial...
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7335483 |
Method of pretreatment of sample for quantitating cholesterol and method for quantitating cholesterol in specific lipoproteins by using the same
A method of a pretreatment of a sample for quantitating cholesterol characterized by, before measuring cholesterol contained in specific lipoproteins, treating the sample containing lipoproteins...
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7285396 |
Aβ-heme peroxidase
Aβ-heme peroxidase activity is selectively measured and inhibited, packaged as a pharmaceutical composition with heme biosynthetic cofactors or as an industrial enzyme, and used to oxidize target ...
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7247726 |
Compounds for generating chemiluminescence with a peroxidase
Novel compounds comprising a C—C double bond substituted at one carbon with two sulfur atom-containing groups are disclosed. The compounds are useful in methods and compositions for generating c...
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7238483 |
Method for detecting catalytic activity
This invention has as its object a method for detecting catalytic activity of a sample, characterized in that it comprises: the incubation of a substrate (S) with the sample that may have the...
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7226753 |
Displacement assay for selective biological material detection
The present invention relates to displacement assay type bioassay materials useful for the detection of toxic substances and, more particularly, to packaging materials for food and other products,...
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7223549 |
Compositions for identification and isolation of stem cells
The invention provides monoclonal antibodies that selectively bind to ectodermally- and endodermally-derived stem cells and methods for the diagnosis of a neoplasm in a subject by contacting a...
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7223546 |
Method for measuring the amount of constituent contained in a specific lipoprotein
There is provided a method and kit for measuring the amount of an objective constituent contained in a specific lipoprotein in a biological sample such as serum and plasma, specifically for...
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