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7582420 |
Multiplex nucleic acid reactions
The invention is directed to a variety of multiplexing methods used to amplify and/or genotype a variety of samples simultaneously.
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7575884 |
Test piece for measuring high-density lipoprotein (HDL) cholesterol
The present invention relates to a test piece having a simple structure, by which HDL cholesterol can be measured easily using a small amount of specimen. A reagent layer ( 2 ) is formed on a...
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7563902 |
Chemiluminescent compounds and their use
The present invention relates to novel chemiluminescent compounds, to a method for synthesizing these compounds, to derivatives and conjugates comprising these compounds, to the use of these...
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7534580 |
PSP94 diagnostic reagents and assays
In the serum, PSP94 occurs as a free form or is associated with a carrier protein. PSP94 in its bound form has been quantified in the blood of prostate cancer patients and these measurements have...
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7527939 |
Polyclonal-monoclonal ELISA assay for detecting N-terminus proBNP
A specific and sensitive in vitro ELISA assay and diagnostic test kit is disclosed for determining levels of NT-proBNP protein in a variety of bodily fluids, non-limiting examples of which are...
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7524642 |
Assays for identifying ubiquitin agents and for identifying agents that modify the activity of ubiquitin agents
Provided are methods and compositions for assaying for ubiquitin agents that are enzymatic components of ubiquitin-mediated proteolysis and, more particularly, methods and compositions for assaying...
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7521200 |
Method for non-invasive rinse diagnosis and monitoring of periodontal diseases using colourimetric reagents
An assay test kit is used in a mouth rinse sample collection procedure involving collecting a mouth rinse sample from a patient. A neutrophil reactant diagnostic reagent is delivered to the rinse...
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7459286 |
Assessing the risk of a major adverse cardiac event in patients with chest pain
Methods for characterizing the near term risk of experiencing a major adverse cardiac event in a patient presenting with chest pain are provided. In one embodiment the method comprises determining...
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7432073 |
Method for detecting guaiacol producing bacteria
The present invention relates to a method capable of detecting proliferative bacteria in food and beverage, particularly acid or neutral beverage at low cost within a short time, a detection kit...
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7422734 |
Methods of producing lignin peroxidase and its use in skin and hair lightening
Methods of producing lignin peroxidase are provided. Also provided are methods and cosmetic compositions suitable for skin and hair lightening as well as kits and an article-of manufacturing...
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7419657 |
Treatment of atherosclerotic disorders
The present invention relates to the identification of lipid oxidizing abzymes as a key pathogenic factor in atherosclerotic disorders. Methods and means for the reduction of abzyme mediated lipid...
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7407743 |
Kit and method of screening wilson's disease
The present invention relates to a method for measuring a ceruloplasmin concentration, and more particularly, to a method for measuring a ceruloplasmin in a blood spot based on a standard...
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7390670 |
Signalling compounds and methods for detecting hydrogen peroxide
Methods and compound useful for detecting a source of hydrogen peroxide are disclosed wherein a signalling compound of the formula:
is reacted with peroxide. Sig is a non-polymeric organic...
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7354733 |
Method for sorting and separating living cells
We disclose methods of sorting or separating mixtures of living cells (e.g., eukaryotic, prokaryotic, mammalian, pathogenic, bacterial, viral, etc.). We perform our methods by activating...
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7354732 |
Method of assay with sulfonic acid compound and nitro compound
A method for measuring an analyte in a sample by using a redox reaction is provided, which gives values with excellent reliability. Prior to the redox reaction, at least one of a sulfonic acid...
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7348135 |
Assay for detecting changes in mitochondrial membrane permeability and method of using same
An assay for assessing the permeability of mitochondrial membranes is provided. The assay is based on enzymatic reactions that produce a detectable signal in the presence of intra-mitochondrial...
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7335483 |
Method of pretreatment of sample for quantitating cholesterol and method for quantitating cholesterol in specific lipoproteins by using the same
A method of a pretreatment of a sample for quantitating cholesterol characterized by, before measuring cholesterol contained in specific lipoproteins, treating the sample containing lipoproteins...
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7285396 |
Aβ-heme peroxidase
Aβ-heme peroxidase activity is selectively measured and inhibited, packaged as a pharmaceutical composition with heme biosynthetic cofactors or as an industrial enzyme, and used to oxidize target...
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7247726 |
Compounds for generating chemiluminescence with a peroxidase
Novel compounds comprising a C—C double bond substituted at one carbon with two sulfur atom-containing groups are disclosed. The compounds are useful in methods and compositions for generating...
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7238483 |
Method for detecting catalytic activity
This invention has as its object a method for detecting catalytic activity of a sample, characterized in that it comprises: the incubation of a substrate (S) with the sample that may have the...
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7226753 |
Displacement assay for selective biological material detection
The present invention relates to displacement assay type bioassay materials useful for the detection of toxic substances and, more particularly, to packaging materials for food and other products,...
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7223552 |
Myeloperoxidase, a risk indicator for cardiovascular disease
Diagnostic tests for characterizing an individual's risk of developing or having a cardiovascular disease. In one embodiment the present diagnostic test comprises determining the level of...
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7223549 |
Compositions for identification and isolation of stem cells
The invention provides monoclonal antibodies that selectively bind to ectodermally- and endodermally-derived stem cells and methods for the diagnosis of a neoplasm in a subject by contacting a...
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7223546 |
Method for measuring the amount of constituent contained in a specific lipoprotein
There is provided a method and kit for measuring the amount of an objective constituent contained in a specific lipoprotein in a biological sample such as serum and plasma, specifically for...
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7195891 |
Methods and compositions of enzymatic cycling based assays for myeloperoxidase
The present invention provides a method for assaying myeloperoxidase activity. In the assay, a sample containing myeloperoxidase or suspected of containing myeloperoxidase is contacted with...
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7186568 |
Electrochemiluminescence from acridan compounds
Methods are disclosed for producing electrochemiluminescence by electrochemically oxidizing an acridan compound at an electrode in the presence of a peroxide. Maintaining a sufficiently positive...
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7153666 |
Methods and compositions for determination of glycated proteins
This invention relates generally to the field of glycated protein detection. In particular, the invention provides chimeric proteins, nucleic acids encoding the chimeric proteins, methods and kits...
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7108997 |
Assay for detecting inhibitors of the enzyme myeloperoxidase
The invention is an assay for detecting inhibitors of the enzyme myeloperoxdase The assay method comprises reacting myeloperoxdase with hydrogen peroxide and a chloride source to generate...
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7091051 |
Chemiluminescence method of 1,2-dioxetane and composition for chemiluminescence
A chemiluminescence method characterized in that when a 1,2-dioxetane derivative of the formula 1:
wherein each of R 1 , R 2 , R 3 , R 4 and R 5 which are independent of one another, is a...
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7041486 |
Enzyme having decolorizing activity and method for decolorizing dyes by using the same
The invention relates to a novel peroxidase enzyme with high dye degradation activity, the genetic information thereof and a method for degrading and decolorizing dye by using the same. The...
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7026122 |
Methods of assaying for compounds that inhibit premature translation termination and nonsense-mediated RNA decay
The present application provides methods of assaying for compounds that inhibit premature translation termination and nonsense mediated RNA decay in cells.
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7022493 |
Ubiquitin conjugation assays
The invention relates to assays for measuring ubiquitin ligase activity and for identifying modulators of ubiquitin ligase enzymes.
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7001741 |
Detection of peroxidase activity in milk or milk products
The invention relates to an agent and a method for the dry chemical detection of lactoperoxidase in milk or dairy products. The method according to the invention is characterized by rapid execution...
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6986998 |
Method of analyzing components in biological samples
There is provided a method for a selective assay of component, particularly cholesterol, in very low-density lipoprotein (VLDL) which is one of serum lipoproteins. In the assay, an enzymatic...
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6979552 |
Method of lipid assay and reagent for use therein
A method of lipid assay characterized by assaying the lipids contained in a blood component in the presence of an organic silicon compound. The method can cause specific conditions for direct...
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6974665 |
In situ screening to optimize variables in organic reactions
A biphasic process for rapid screening of organic reactions comprising monitoring relative rates of parallel organic reactions. The screening process is suitable to determine the efficacy of...
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6960323 |
Compositions containing a urea derivative dye for detecting an analyte and methods for using the same
Compositions, reagent test strips, analyte detection systems and kits of the same, as well as methods for their use in the detection of an analyte in a sample, are provided. The subject...
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6939682 |
Test piece for assaying high density lipoprotein (HDL) cholesterol
The present invention relates to a test piece having a simple structure, by which HDL cholesterol can be measured easily using a small amount of specimen. A reagent layer ( 2 ) is formed on a...
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6911305 |
Method for chemiluminescent detection
The invention provides chemiluminescent assays that incorporate a film including at least one chemiluminescent precursor immobilized therewith which produces a triggerable chemiluminescent...
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6897036 |
Fluorescent detection of peroxidase enzymes
Methods of producing fluorescence from fluorogenic substrates reactive with a peroxidase enzyme are disclosed. Use of the methods in assays for peroxidase enzymes, peroxidase-labeled analytes are...
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6897035 |
Biosensor
The present invention relates to a biosensor for the detection and/or the determination of freshness biomarkers, such as biogenic amines (preferably histamine) in food and beverage, comprising an...
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6884601 |
Method to detect fertilization potential of sperm
The invention relates to a method to detect male antifertility problems based on the determination of latent phospholipid hydroperoxide glutathione peroxidase (PHGPx).
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6881550 |
Method for the determination of glucose employing an apparatus emplaced matrix
A method for determining the presence of an analyte in a fluid is described along with various components of an apparatus specifically designed to carry out the method. The method involves taking a...
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6867012 |
Determination method of biological component and reagent kit used therefor
The present invention provides novel glutathione-dependent formaldehyde dehydrogenase that makes possible quantitative measurement of formaldehyde by cycling reaction, and a determination method of...
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6858401 |
Minimum procedure system for the determination of analytes
A method for determining the presence of an analyte in a fluid is described along with various components of an apparatus specifically designed to carry out the method. The method involves taking a...
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6852503 |
Compositions and methods for utilizing mixed substrate solutions of luminols and dioxetanes
A dual enzyme chemiluminescent substrate formulation useful for the independent or simultaneous analysis of the enzymes is disclosed, the formulation includes, as one substrate component,...
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6849419 |
Monoclonal antibody hybridoma immunoassay method and diagnosis kit
The object of the present invention is to provide a diagnostic method by which Helicobacter pylori infection can be diagnosed at low cost without causing pain on subjects and without requiring...
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6831173 |
Process for selective oxidation of primary alcohols and novel carbohydrate aldehydes
A process for producing aldehydes, and/or carboxylic acids is described, in which a primary alcohol, especially a carbohydrate, is oxidized using a catalytic amount of a nitrosonium compound...
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6811994 |
Method for quantitating triglycerides in lipoproteins
The present invention relates to a method for conveniently quantitating TGs contained in various lipoproteins. A method for quantitating trigyceride (TG) in a particular lipoprotein which comprises...
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6808914 |
Process for the preparation of L-amino acids by fermentation and nucleotide sequences coding for the accDA gene
The invention relates to nucleotide sequences coding for the accDA gene and to a process for the preparation of L-amino acids, especially L-lysine, by fermentation using corynebacteria in which the...
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