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7091180 |
Hyaluronic acid and chondroitin sulfate based hydrolyzed collagen type II and method of making same
Hydrolyzed collagen type II powder compositions for inducing cartilage formation in an individual, method of preparing the compositions and use of the compositions in treating connective tissue...
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6780841 |
Hyaluronic acid and chondroitin sulfate based hydrolyzed collagen type II and method of making same
Hydrolyzed collagen type II powder compositions for inducing cartilage formation in an individual, method of preparing the compositions and use of the compositions in treating connective tissue...
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6679918 |
Implantable putty material
The present invention provides compositions for an implantable putty material for delivery of active compounds to a patient. More specifically, the present invention provides a material having a pH...
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6346515 |
Collegan-based matrix
A collagen matrix comprises collagen fibrils which are cross-linked to one another by reducing sugar or a reducing sugar derivative. The collagen matrix may be formed into a membrane useful in...
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6323319 |
Method of making hydrolyzed collagen type II
Hydrolyzed collagen type II powder compositions, method of preparing the compositions and use of the compositions in treating cartilage defects. The compositions are orally administered to an...
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6184011 |
Method of releasing solid matrix affinity adsorbed particulates
A method of releasing particulates from a solid matrix is provided. The method is effected adding to the solid matrix a degrading enzyme capable of degrading the solid matrix, to thereby release...
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6183741 |
Method for reducing insolubles in a gelatin solution
The present invention is a process for reducing gelatin insolubles which includes providing a gelatin solution and adding to the gelatin solution amylase in an amount to provide a concentration of...
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6100381 |
Enzyme method of manufacturing gelatin
The present invention is a process for the manufacture of gelatin which includes providing a collagen containing material and demineralizing the collagen containing material to produce ossein. An...
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6096346 |
Method of obtaining extract of shark's cartilage
A method of obtaining an extract of shark's cartilage is provided wherein a shark's cartilage is processed through five steps. The five steps are smashing, cleaning, purifying, deodorizing, and...
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6080843 |
Gelatin and method of manufacture
The present invention is a gelatin composed of a high molecular weight fraction (>250,000) of from 0 to 25 wt %, a beta fraction (150,000-250,000) of from 0 to 20 wt % and an alpha fraction...
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6043078 |
Method for the reduction of biological growth in solution
The present invention is a process for reducing biological growth in aqueous solutions. An aqueous solution is provided. An amylase solution is added to the aqueous solution to provide an amylase...
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6040155 |
Multifunctional protein and DNA sequence encoding same
The present invention provides nucleic acid and corresponding amino acid sequences of a multifunctional protein that has been found to be useful in numerous medical and cosmetic contexts. A protein...
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6037451 |
Method of degreasing bone for gelatin manufacture
The present invention is a process for degreasing bone for the manufacture of gelatin. A lipase solution at a concentration of greater than 0.1 ppm is added to a collagen containing material and...
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6025327 |
Hydrolyzed collagen type II and use thereof
Hydrolyzed collagen type II powder compositions, method of preparing the compositions and use of the compositions in treating cartilage defects. The compositions are orally administered to an...
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5955438 |
Collagen-based matrix
A collagen matrix comprise collagen fibrils which are cross-linked to one another by a reducing sugar or a reducing sugar derivative. The collagen matrix may be formed into a membrane useful in...
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5861495 |
Human zinc binding proteins
The present invention provides three zinc binding proteins (designated individually as ZB-1, ZB-2, and ZB-3, and collectively as ZB) and polynucleotides which identify and encode ZB. The invention...
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5831052 |
New human translocation associated protein
The present invention provides a human translocation associated protein (Gp25L-H) and polynucleotides which identify and encode Gp25L-H. The invention also provides expression vectors, host cells,...
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5831049 |
Human thioredoxin
The present invention provides a human thioredoxin (TRDX) and polynucleotides which identify and encode TRDX. The invention also provides genetically engineered expression vectors and host cells...
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5830660 |
Tumorigenesis protein
The present invention provides a human tumorigenesis protein (HTAP) and polynucleotides which identify and encode HTAP. In addition, the invention provides expression vectors and host cells,...
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5810970 |
Paper strengthened with solubilized collagen and method
A method for making a collagen strengthened cellulosic sheet by providing a cellulosic pulp slurry; adding solubilized collagen to the pulp slurry, and mixing for a time effective for interaction...
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5711853 |
Paper strengthened with solubilized collagen and method
A method for making a collagen strengthened cellulosic sheet by providing a cellulosic pulp slurry; adding solubilized collagen to the pulp slurry, and mixing for a time effective for interaction...
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5686262 |
Recycle process for the production of low-cost soluble collagen
The invention includes a method that provides a low cost aqueous solution of solubilized collagen by the steps of: (a) providing an aqueous ground slurry of insoluble collagen and adjusting the pH...
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5670369 |
Method for the production of soluble collagen
The invention includes an improved method for producing an aqueous solution of soluble collagen. The method comprises the steps of: (A) providing an aqueous ground slurry of insoluble collagen...
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5667839 |
Human recombinant collagen in the milk of transgenic animals
Production of human procollagen or collagen in cells which ordinarily do not produce these molecules is effected by constructing expression systems compatible with mammary glands of non-human...
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5647957 |
Method of preparing paper strengthened with solubilized collagen
A method for making a collagen strengthened cellulosic sheet by providing a cellulosic pulp slurry; adding solubilized collagen to the pulp slurry, and mixing for a time effective for interaction...
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5606019 |
Synthetic protein as implantables
Copolymers are provided having varying ratios of elastin and fibroin repeating units. By varying the length of segments of the elastin and fibroin repeating units, the absorption can be greatly...
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5418157 |
Recombinant 68,000 dalton collagenase of Clostridium histolyticum
Genetically engineered E. coli carry vectors containing inserts that code for Clostridium histolyticum collagenase. These inserts code for: (a) a form of collagenase having a molecular weight of...
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5411887 |
Method for the production of collagen: collagen produced through the method and use of collagen
The present invention relates to a process for the production of collagen from animal intestines etc. It is characterized in that the starting material is mixed with ice-water at a pH of 5,5, that...
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5316942 |
Process for the production of low-cost soluble high-molecular weight collagen
The invention includes a method that produces a low cost aqueous solution of high molecular weight solubilized collagen by the steps of: (a) providing an aqueous ground slurry of insoluble...
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5162506 |
Process for preparing collagen fibers from tissue
The invention relaates to the production of collagen fibers by comminuting collagen containing tissues, drying the comminuted product and milling the dried material while maintaining the...
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5147787 |
Recovery of imageable polyacetylenes from binder containing aqueous dispersions
This invention relates to a process for the recovery of a substantially insoluble, radiation imageable polyacetylene dispersion in aqueous binder which comprises contacting the dispersion with a...
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5007995 |
Device for electrofusion of cells
A device and a method for fusing biological cells. The device is formed by a chamber having a tube for containing a cell suspension and a cover for sealing the tube. The chamber is provided with a...
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4829000 |
Reconstituted basement membrane complex with biological activity
The present invention discloses a biologically active basement membrane composition. When polymerized under physiological conditions, the composition forms gel-like structures whose ultrastructure...
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4798800 |
Process for isolating human globular domain NC1 of basal membrane collagen from human tissue
The present invention provides human characterized by a molecular weight of about 170,000 Dalton, a hexameric structure with monomeric subunits with a molecular weight of about 28,000 Dalton and a...
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4642292 |
Method for isolation of connective tissue biomatrix
A method is disclosed for isolation of connective tissue fibers, called biomatrix, containing a significant portion of the extracellular matrix, i.e., basement membrane components and components of...
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4621631 |
Process for the production of a bonded collagen fiber sheet
A process for the production of an unnative and biologically active bonded collagen fiber sheet from human placentae is described, in which process collagen-containing material from placentae is...
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4597762 |
Collagen preparation
A collagen preparation comprising collagen-I for human or veterinary medicine obtainable by proteolyzing, cross-linking, reducing, optionally heat treating, and finally sterilizing mammalian...
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4544638 |
Synthesis of cross-links in the helical domain of collagen using pyridoxal 5-phosphate and copper or iron
Aldehyde cross-link intermediates and cross-links are generated in the central helical portion of collagen by incubating collagen with pyridoxal-5-phosphate and either cupric copper ion or ferrous...
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4501815 |
Article for culturing differentiated cells
A method, solid-state culture support and culture solution are disclosed which enables successful in vitro culturing of differentiated cells, with significant retention of their differentiated...
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4439522 |
Proteolytic enzyme composition
A proteolytic enzyme-containing composition is prepared having stabilized proteolytic enzyme activity and the ability to convert scleroproteins to water soluble products without racemization. The...
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4407829 |
Method of manufacturing collagen products
The present invention relates to the manufacture of a collagen slurry which can be used, inter alia, for manufacturing casings for food products. When manufacturing the slurry, various parts of the...
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4404134 |
Collagen sponge
Process for the manufacture of a collagen solution and its use for the manufacture of collagen fibrillae for adsorbing coagulation factors, as diagnostic agent, for the manufacture of a collagen...
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4389487 |
Process for the preparation of a collagen product for medical and cosmetic purposes
Process for the preparation of collagen products for medical and cosmetic purposes, wherein collagen products prepared according to the method described in U.S. Pat. No. 4,066,083 are subjected to...
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4374830 |
Platelet aggregating material from equine arterial tissue
Novel hemostatic agent comprises equine arterial fibrillar collagen in a carrier. The agent is useful for the aggregation of platelets for clinical diagnostic tests and for the clotting of blood,...
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4331766 |
Collagen solution, process for its manufacture and its use
Process for the manufacture of a collagen solution and its use for the manufacture of collagen fibrillae for adsorbing coagulation factors, as diagnostic agent, for the manufacture of a collagen...
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4320201 |
Method for making collagen sponge for medical and cosmetic uses
A process for producing collagen sponge which is insoluble but highly swellable in water, the sponge having a velour-like surface and being particularly suited for medical and cosmetic applications.
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4271070 |
Chemically-modified fiber collagen hemostatic agents
Chemically-modified quaternary-structured fiber collagens of minimum molecular length, diameter and periodicity, and containing a relatively high positive electrostatic charge are claimed as...
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4268131 |
Fiber collagen contact lens
Soft contact lenses are made from purified fiber collagen and mixtures of such fiber with purified solubilized collagen.
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4264155 |
Collagen contact lens
Improved soft contact lenses are made from collagen gels to which water-soluble organic polyhydroxy polymers are added, e.g. mucopolysaccharides, polyvinyl alcohols, etc.
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4260228 |
Collagen gel contact lens and method of preparation
An improved collagen gel soft contact lens is prepared from an aldehyde-crosslinked, lens-shaped collagen gel containing a water-soluble, aliphatic, monomeric, polyhydroxy compound, e.g., glucose.
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