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7678583 Method of lysis of erythrocytes  
A multifunctional reagent for erythrocytes containing an amount sufficient to produce the lysis of erythrocytes or the sphering of erythrocytes in such a way that they can be detected by a...
7485855 On-probe sample cleanup system and method for MALDI analysis  
A system and method for cleanup of biological samples from contaminants prior to spectroscopy analysis. The system includes a support configured to hold a sample including a liquid having at least...
7323315 Method for reducing effect of hematocrit on measurement of an analyte in whole blood  
A method for determining the presence and/or amount of an analyte in a sample of whole blood comprises the step of treating the sample with a nonlytic hypertonic salt composition to reduce the...
7029906 Carbonyl stress-ameliorating agents  
Carbonyl stress-ameliorating agents have been provided, which contain an enzyme having a glyoxalase I activity and a carbonyl compound-reducing agent as the active ingredients. The carbonyl...
7026131 Methods and apparatus for blood typing with optical bio-discs  
This invention relates to clinical diagnostic assays, related optical bio-discs, and a disc-reading apparatus. The invention is directed to methods and apparatuses for performing immunohematology...
6942879 Bioartificial filtration device for filtering blood to mimic kidney function  
A novel cell seeded hollow fiber bioreactor is described as a potential bioartificial kidney. Endothelial cells along with pericyte, vascular smooth muscle, and/or mesangial cells or any...
6767723 Method for synthesis of nucleic acids  
An object of the present invention is to provide a method of treatment and a method of storage that are useful in conducting a nucleic acid synthesis procedure capable of directly amplifying an...
6709655 Pharmaceutical composition of F(ab1)2 antibody fragments and a process for the preparation thereof  
The present invention is directed to a pharmaceutical composition comprising F(ab′)2 antibody fragments that are preferably free from albumin and of whole antibodies and also substantially free o...
6475478 Adsorbent, adsorbing and removing process and adsorber for endogenous cannabinoid  
There are provided an adsorbent which can effectively adsorb and remove endogenous cannabinoid in fluid, and a process for removing endogenous cannabinoid in fluid by means of the adsorbent. The...
6297371 Process for the preparation of endotoxin-free or endotoxin-depleted nucleic acids and/or oligonucleotides for gene therapy  
A process for the isolation and purification of nucleic acids and/or oligonucleotides for use in gene therapy wherein said nucleic acids and/or oligonucleotides are isolated or purified from an...
6218101 Enzymatic method for removal of cryoprotectants from cryopreserved animal cells  
A method to remove cryoprotectants from cryopreserved biological cells and tissues is described. Enzymes are used to convert compounds used as cryoprotectants for cells during cryopreservation to...
6187553 Method of using additive formulation and method for making a tube with an additive formulation  
An additive formulation comprising heparinase and trehalose, a method for using the formulation and a device containing the formulation. The additive formulation is useful in substantially...
6107455 Removal of protein from natural rubber latex articles  
A method for lowering the extractable protein content in a natural rubber latex to below 30 parts per million (ppm) comprises the steps of treating by washing a rubber article, such as a rubber...
5910422 Stable single liquid alpha-amylase reagent  
A stable, single liquid alpha-amylase assay reagent comprises a polysaccharide or long chain oligosaccharide substrate for alpha-amylase having an optically detectable label bonded to the reducing...
5866317 Method for collecting hemolymph of insects  
The present invention herein provides a method for collecting insect hemolymph which permits the collection of hemolymph, at a time, from a vast number of insect bodies, which does not cause any...
5770104 Detergent compositions containing substantially pure EG III cellulase  
Disclosed are detergent compositions containing a cleaning effective amount of a surfactant or a mixture of surfactants and from about 0.01 to about 5 weight percent of substantially pure EG III...
RE35747 Method for determining tissue of origin and presence and extent of cellular abnormalities  
A biochemical procedure for identification and characterization of cells in a biopsy or sample of a body fluid. The method can be used to determine cell type, i.e. epidermal, neuronal; tissue of...
5665762 Decontaminating clinical samples  
The present invention contemplates methods of decontaminating human fluids prior to processing in the clinical laboratory. The techniques handle large volumes of human serum without impairing the...
5633130 Buffer system for increasing seroconversion efficiency  
A method of increasing efficiency of deantigenation of blood group epitopes on erythrocytes (seroconversion) by exoglycosidases utilizing a step of performing the deantigenation in a zwitterionic...
5629198 Anti-HIV agent  
The invention relates to an anti-HIV agent comprising, as an active ingredient, at least one porphyrin derivative selected from the following derivatives (A) and (B): (A) porphyrins modified with a...
5543115 Specimen handling device  
This invention relates to a specimen handling device for collecting, storing, processing and dispensing of samples. The invention provides for the collection of specimens from any solid or...
5501963 Amplification and detection of nucleic acids in blood samples  
This invention relates to a process for the amplification of nucleic acids in the form of DNA or RNA from blood samples by means of an enzymatic amplification method, characterized in that no...
5324628 Use of chymotrypsin for the inactivation of prekallikrein activator  
In order to avoid the risk of undesired side reactions of blood products, the latter are produced from plasma by using chymotrypsin to inactivate prekallikrein activator. These preparations are...
5262325 Method for the enzymatic neutralization of heparin  
A heparinase formulation derived from Flavobacterium heparinum which meets all requirements for a clinical reagent that can eliminate heparin interference of normal blood function has been...
5234685 Method of determining incompatibility-reaction-causing substances in blood products as well as a method of inactivating said incompatibility-reaction-causing substances  
There is disclosed a method of determining the presence of incompatibility-reaction-causing substances in blood products. There is also disclosed a method of inactivating...
5231015 Methods of extracting nucleic acids and PCR amplification without using a proteolytic enzyme  
This invention provides a rapid and highly effective method for extracting nucleic acids from cells or virions without the use of proteolytic enzymes. Extraction is accomplished within a few...
5149633 Process and reagent for the specific determination of fructosamine content in blood and samples obtained from blood  
Process for the specific determination of the serum fructosamine content in blood or in samples obtained from blood by reaction with an appropriate color reagent and measurement of the color change...
5089415 Method for clotting heparized blood by the addition of protamine, thrombin and snake venom  
A cocktail reagent preparation for the rapid production of serum contains thrombin, snake venom, and protamine sulfate. The preparation employs very small quantities of clot promoting substances...
5055388 Process and reagent composition for determination of fructosamine in body fluids  
A process for the determination of fructosamine in body fluids by the reaction of a sample solution with a color reagent, wherein the sample liquid is mixed with a buffer solution having a pH value...
4997932 Method and kit for purifying nucleic acids  
The invention teaches a method and kit for purifying nucleic acid, such as DNA, from a sample, such as lysed cell or tissue sample. A sample is applied to an anionic exchange matrix column...
4945055 Human chorionic gonadotropin releasing factor  
A substantially purified human chorionic gonadotropin releasing factor (hCG-RF) which is a glycoprotein with a molecular weight between about 50,000 and about 70,000. This hCG-RF is capable of...
4920045 Detection of occult blood in feces  
A method for detection of occult blood in a fecal sample which comprises acting a glycosidase type bacteriolytic enzyme on the fecal sample and subjecting the resulting fecal sample to simultaneous...
4908318 Nucleic acid extraction methods  
A method of extracting nucleic acids from a crude buffy coat fraction in an aqueous medium includes the steps of treating the buffy coat fraction to break open the white blood cells to release the...
4882268 Method for determining tissue of origin and degree of malignancy of tumor cells  
A biochemical procedure for diagnosis of three important properties of cells in a biopsy or blood sample: tumor type i.e., the tissue type that has become neoplastic; tissue of origin if the tumor...
4866033 Oligopeptides from bovine blood  
Oligopeptide mixtures from deproteinized bovine blood dialyzate which are characterized by their RF values in thin-layer chromatography, as well as a method for their preparation.
4820416 Removal of bilirubin by the pseudoperoxidase activity of immobilized hemoglobin  
The present invention relates to a process for oxidizing bilirubin which comprises reacting a solution containing bilirubin with hemoglobin, either in free or immobilized form, in the presence of...
4814277 Method of inactivating reproductive filterable pathogens  
A method of inactivating reproductive filterable pathogens in immunoglobulin-G-containing blood fractions to be applied therapeutically or prophylactically. In order to preserve full activity of...
4693972 Composition and method for rapid detection of microorganisms in clinical samples  
A method for rapid detection of microorganisms in a body fluid sample includes detecting the microorganisms after treatment of the sample with a lysing agent in order to dissolve sample components...
4693982 Enzymatically-treated guar gums  
Aqueous guar gum compositions having a very low content of insolubles, the compositions being formed by impregnating free-flowing solid, particulate guar gum with one or more hydrolytic enzymes and...
4609627 Enzymatic conversion of certain sub-type A and AB erythrocytes  
Type O erythrocytes are produced from certain subtypes of A erythrocytes or type AB erythrocytes by contacting the same following equilibration of a pH of 5.6-5.8 with an...
4608253 Process for removing immune complex in blood by use of the immobilized pepsin  
The present invention relates to immobilized pepsin for use in removing immune complex which comprises pepsin fixed on a suitable carrier, and to a process for removing immune complex which...
RE31517 Method for quantitative determination of renin activity in blood employing phenyl methyl sulfonyl fluoride and polyethylene glycol  
A method for the quantitative determination of renin activity in blood utilizing the measurement of Angiotensin I by treating the blood with ethylenediaminetetraacetic acid (EDTA) and the plasma...
4411915 Heme-iron-enriched amino acid and a process for the preparation of heme-iron-enriched amino acid  
There is disclosed heme-iron-enriched amino acid preparation consisting of aggregates of heme-protein fragments with heme bonded to histidine groups present in the fragment and a method for...
4396762 Heparinase derived anticoagulants  
There is disclosed a heparin product obtained by degradation of heparin with heparinase from Flavobacterium heparinum (ATCC 13125) or mutants thereof having activity to reduce the coagulation...
4386161 Process for the preparation of incoagulable blood by means of proteolytic enzymes and protein concentrate prepared therefrom  
Proteolytic enzymes, particularly papain, are used for rendering whole blood incoagulable. The treatment is preferably carried out at a pH of 7.2 with a ratio between enzyme and substrate, for...
4361484 Process for treating and/or removal of substances from liquid, especially whole blood  
A process for the treating of and/or removal of substances from a liquid, especially whole blood, via a semipermeable microporous membrane (13, 14, 15) through adsorption and/or biological reaction...
4356267 Enzyme immobilization in cellulosic hollow fibres  
Enzymes are immobilized in a bundle of cellulosic hollow fibres for use as a fibre-bundle dialyzer for purifying blood. Immobilization is carried out by circulating through the lumen of the fibres...
4312949 Method for the preparation of a gamma globulin solution suitable for intravenous use  
A gamma globulin solution suitable for intravenous use is prepared by treating the gamma globulin fraction of plasma or serum obtained in known manner with a peptic enzyme at a pH value of about 4....
4248704 Phenylalanine ammonia lyase occluded fibers for reducing phenylalanine blood-level  
Phenylalanine level in blood or another medium is considerably reduced and can even be annulled by causing blood or the other medium to flow through a mass of porous fibers in which the enzyme...
4247632 Methylguanidine-decomposing enzyme and process for its production  
A novel methylguanidine-decomposing enzyme can be obtained by cultivating in a medium a bacterium belonging to Genus Alcaligenes and having an ability to produce a methylguanidine-decomposing...
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