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5089388 Antibodies for salicylate and their preparation  
Conjugates of salicylic acid and certain poly(amino acids), which are either antigenic or enzymes, are provided. Antibodies raised against the antigenic poly(amino acids) and the enzyme conjugates...
5085989 Method and reagent for quantitative analysis of 3-oxo-5β-steroid  
A quantitative analysis of 3-oxo-5β-steroid is carried out by acting 3-oxo-5β-steroidΔ4 -dehydrogenase on a sample in the presence of a reducing chromophoric agent, and measuring the optical...
5082770 Method for quantitative determination of polyamines  
A method for the quantitative determination of polyamines, which comprises allowing a polyamine oxidizing enzyme, an ω-aminoalkylaldehyde dehydrogenase, an oxidized nicotinamide coenzyme and, as...
5081016 Method for measuring the amount of polyamines in a biological sample  
A method for measuring the amount of polyamines in a biological sample is provided. The method comprises utilizing diamine oxidase and/or polyamine oxidase, aminoalkylaldehyde dehydrogenase and...
5081014 Method of measuring a co-enzyme  
The method makes use of the action of the co-enzyme in the production of H2 O2 associated with the reaction of a hydroxylase with a decoupling agent in the presence of air or oxygen, the H2 O2...
5068190 N-acetylhexosamine-dehydrogenase, process for producing same, method for the quantitative analysis of N-acetylglucosamine or N-acetylgalactosamine using same and kit for use in the quantitative analysis  
N-Acetylhexosamine-dehydrogenase which takes off hydrogen from N-acetylglucosamine or N-acetylgalactosamine to convert them to N-acetylglucosaminolactone or N-acetylgalactosaminolactone,...
5059526 Dry multilayer analytical element for analysis of enzymes or triglycerides  
A stable dry multi-layer analytical element for enzyme or triglyceride analysis in a fluid sample is prepared containing first and second layers on a support. The first layer contains a...
5047322 Use of dry analytical elements to determine analytes  
Dry transparent analytical elements can be used to determine analytes which have been separated by electrically induced migration through a solid medium, e.g. by electrophoresis, or which are...
5041373 Method for determining periodontal disease  
An objective method for determining the presence of active periodontal disease in mammals, comprising assaying cervicular fluid for the presence of elevated levels of the enzyme aspartate...
5037738 Simultaneous assay for glucose and urea  
A method for the simultaneous determination of glucose and urea in a specimen with a single reagent system. A reagent system containing a reactant for each of glucose and urea to be determined is...
5037739 N-acetylmannosamine dehydrogenase, process for its production, method for quantitatively analyzing N-acetylmannosamine or sialic acid, and kit for the quantitative analysis  
N-Acetylmannosamine dehydrogenase which takes off hydrogen from N-acetylmannosamine to convert it into N-acetylmannosaminolactone and, at the same time, reduces coenzyme NAD into NADH. This enzyme...
5035995 Test method involving substance-conjugated complement component C1q  
A substance-conjugated complement component C1q is provided. A substance such as signal emitting substances or cell function regulating substances is conjugated via a sulfur atom to at least one...
5036000 Threshold color control system  
A system for quantitative colorimetric analysis of biological fluids or organic compounds, including NAD(P)H, or a substrate of an enzyme which reacts with the formation or consumption of NAD(P)H....
5032506 Color control system  
An assay system useful for the determination of NAD(P)H, NAD(P), or a substrate of an enzyme which reacts with the formation or comsumption of NAD(P)H. Concentrations of organic substrates for...
5026635 Stable human cell lines expressing an indicator gene product under virus-specific genetic controls  
The invention relates to stable mammalian cells lines having integrated in their genome two heterologous DNA sequences, a first DNA sequence which expresses a trans-acting regulatory protein, and...
5013648 Enzymatic detection of monovalent anions  
An enzymatic reagent, kit and method for determining the concentration of monovalent anions, especially chloride, particularly in clinical samples, and especially in a single-reagent format...
5013647 Removal of interfering reducing substances with tetrazolium salts in redox measurement reactions  
A process for the determination of substrate or enzyme activities by the use of a redox reaction as a measurement reaction is carried out in the presence of one or more additionally added...
5009994 Particles containing mannitol suitable for tabletting into diagnostic reagents  
A completely water-soluble, solid, labile biochemical-containing diagnostic reagent is prepared without the need of a lyophilization step, by spraying, preferably by a fluidized bed process, an...
5006458 Analytical element having a polyacrylamide or derivative to minimize background for assaying enzyme activity  
A dry-type analytical element suitable for measuring enzyme activity of in a liquid sample, characterized by incorporating a polyacrylamide, polymethacrylamide or their derivatives into at least...
5002886 Oxidoreductase and the preparation thereof  
An oxidoreductase is provided which, in the presence of nicotinamide adenine dinucleotide (NAD+) as a co-enzyme, will catalyse the oxidation of polyols having at least one hydroxyl group on each...
4994375 Stable human serum based control and/or calibrant  
A stable human serum based control for the assay of Total LD and CK and their isoenzymes. This control may be lyophilized and reconstituted and still provide the same enzyme activity prior to...
4990445 Stable reagent and kinetic assay for alpha-amylase  
A stable reagent and kinetic assay for α-amylase is provided. The reagent comprises a substrate for the α-amylase and various enzymes and cofactors necessary to produce NADH as the end-product of...
4983513 Sulfhydryl compounds for suppressing the inhibitory effects of NAD degradation products on LD-L activity  
A liquid coenzyme reagent comprises the coenzyme nicotinamide adenine dinucleotide (NAD), or nicotinamide adenine dinucleotide phosphate (NADP), and a sulfhydryl compound capable of counteracting...
4978615 Method for the determination of the compound having mercapto group  
The present invention provides a method for the determination of a compound having mercapto group which comprises reacting the compound with a chromogen represented by the following general...
4975367 Catalytic test composition intended to produce a range of colors  
Test compositions, indicators, and test device are provided which are capable of generating different hues at different analyte concentrations. The compositions are capable of generating a yellow...
4973550 Process for the electrochemical regeneration of co-enzymes  
A process for the electrochemical regeneration of a co-enzyme, which process comprises the steps of (i) electrochemically oxidizing a medium containing oxidized co-enzyme and biochemically...
4963479 Reagent system for an alpha-amylase assay containing aromatic substituted glycoside  
An aromatic substituted glycoside is disclosed of the formula ##STR1## wherein the configuration of the substituted --OR on the anomeric carbon is alpha, n is an integer of 0 to 1, and R is a...
4956276 Analytical method of determining a reduced co-enzyme  
The sample for analysis containing the co-enzyme to be detemined, inter alia NADH or NADPH, is placed in the presence of a fluorinated aromatic compound. In the presence of oxygen and peroxidase,...
4946776 Stable chromogenic substrate mixture of indoxyl phosphate and tetrazolium salt, method of making and using same in biological and diagnostic assays  
A stable chromogenic substrate mixture of indoxyl phosphate and tetrazolium salt is prepared by dissolving the phosphate in DMF and combining the same with Tris buffer containing magnesium...
4945045 Electrochemical methods of assay  
A ligand in a sample can be assayed using electrochemical apparatus containing a working electrode and components comprising: (a) the sample, (b) a specific binding partner to the ligand, or a...
4939085 Oxidized coenzyme-containing dry analytical element  
A dry analytical element having functional layers which contain dehydrogenase, oxidized nicotinamide coenzyme, pyruvate, an electron transport compound and an electron acceptable dye-forming...
4927753 Quantitative determination of L-fucose  
A method is provided for the quantitative determination of L-fucose in a sample solution. According to the method an L-fucose dehydrogenase having its optimum pH around neutrality is allowed to...
4927752 Support used in bioluminescent dosing of enzymes, substrates or enzymatic inhibitors  
Method for the bioluminescent dosing of enzymes, substrates or enzymatic inhibitors, characterized in that there is used a transparent support made of synthetic plastic material previously treated...
4923803 Method for determining galactitol  
The galactitol level in the body fluid, e.g. blood or urine, is determined by the method that comprises allowing a body fluid sample to contact in vitro with a bacterium capable of producing...
4923796 Method for the quantitative enzymatic determination of ADP  
In a method for the quantative enzymatic determination of adenosine diphosphate (ADP) in aqueous solution by phosphorylation of the ADP with a kinase in the presence of a phosphorylated substrate...
4921786 Novel NAD synthetase, assay method using said novel NAD synthetase and a process for production thereof  
A novel NAD synthetase is produced by culturing a broth of Bacillus stearothermophilus H-804 FERM BP-1408. This new enzyme selectively catalyzes the reaction ##STR1## without catalyzing the...
4914020 Multi-layer analytical element with preserved enzyme containing spreading layer  
An analytical element to measure a specific component in a fluid samples comprising support, a layer containing a reagent provided the support and a spreading layer provided on above the reagent...
4897346 Stabilized liquid enzyme composition for glucose determination  
A homogeneous liquid enzyme reagent for the quantitative determination of glucose comprises the enzymes hexokinase and glucose-6-phosphate dehydrogenase in a solution of glycerol (30% v/v) in...
4892816 Method for the determination of cholesterol  
An enzymatic method for measurement of cholesterol comprises incubating: (a) a test sample; (b) a cholesterol dehydrogenase; (c) an oxidizing agent selected from the group consisting of...
4888289 Reagent for determining creatine kinase  
A reagent for the determination of creatine kinase is comprised of a reagent group containing N-acetylcysteine and ethylenediaminetetraacetic acid and a reagent group containing magnesium, whereby...
4883579 Photoresponsive redox detection and discrimination  
Devices and methods are provided for making a plurality of determinations of the local (site-specific) redox state of a liquid system, by employing a photoresponsive element, which can be...
4882423 Substance-conjugated complement component C1q  
A substance-conjugated complement component Clq is provided. A substance such as signal emitting substances or cell function regulating substances is conjugated via a sulfur atom to at least one...
4876191 Immobilization of biologically active substances with carrier bond antibody  
The invention relates to compositions which are capable of selectively binding a biologically active protein, retaining its activity. Such compositions have essentially three parts, linked...
4874696 Novel bacterium inducible to produce unique steroid-transforming enzymes: preparation and applications thereof  
The present invention discloses a unique biologically pure culture of a microorganism belonging to Alcaligenes species. The microorganism has the property of producing novel 17β-hydroxysteroid...
4861709 Detection and/or identification of microorganisms in a test sample using bioluminescence or other exogenous genetically-introduced marker  
A method for determining the presence of microorganisms in a tests sample. Exogenous DNA containing a luminescent system or other genetic marker system derived from a suitable donor source is...
4857319 Method for preserving liposomes  
A method for preserving liposomes includes freeze-drying liposomes most preferably having an average size of about 50 nm to 100 nm with a disaccharide preserving agent being present both...
4849347 Colorimetric biological assay  
Lactic acid produced by cells in culture is detected and used in a bioassay to determine cell growth and vitality. Lactic acid is detected by coupling the lactate dehydrogenase conversion of...
4847195 Glucose-6-phosphate dehydrogenase conjugates useful in polyiodothyronine assays  
Polyiodothyronine analog conjugates to glucose-6-phosphate dehydrogenase (G6PDH) are provided which find use in the determination of polyiodothyronine compounds, particularly thyroxine, normally...
4847196 Stabilized composition of tetrazolium salts  
The present invention provides stabilized compositions of tetrazolium salts for analytical purposes which contain 1 to 10 moles of a complex forming acid which is soluble in polar solvents, per...
4845028 Composition for lipase assay  
A composition and method for lipase assay, comprising the use of an aqueous solution of a 1,2-diglyceride of a higher fatty acid, and a nonionic surface active agent. The higher fatty acid is a...