|
Match
|
Document |
Document Title |
|
|
7381553 |
Highly active xylose reductase from Neurospora crassa
A new xylose reductase encoding gene from Neurspora crassa was heterologously expressed in E. coli as a His-tag fusion protein and subsequently purified in high yield. This xylose reductase was...
|
|
|
7381545 |
Method for controlling metallophosphate precipitation in high cell density fermentations
The invention relates to the use of a phosphate glass as a phosphorous source in the media of high cell density bacterial fermentation processes in order to reduce metallophosphate precipitation...
|
|
|
7374945 |
Method for enhancing the association rates of polynucleotides
The present invention features a method and associated kit for increasing the association rate between polynucleotides having complementary, single-stranded regions, where the method includes...
|
|
|
7368277 |
Method for assay of antibodies and antibody assay device
The invention relates to a technology by which antibodies directed to sources of infection in body fluids can be assayed with high accuracy, expediency and specificity. More particularly, the...
|
|
|
7358070 |
Process for formation of pattern of polyhydroxyalkanoate
A process for forming a fine pattern comprised of a polyhydroxyalkanoate on a substrate is provided. The process comprises steps of applying a polyhydroxyalkanoate-synthesizing enzyme and a...
|
|
|
7338791 |
Production of flavonoids by recombinant microorganisms
Methods and compositions are provided for production of flavonoids in microbial hosts. The compositions comprises a set of genes which encode for enzymes involved in one or more steps in the...
|
|
|
7335502 |
Chlorohydrin and hydroxycarboxylic ester asymmetric hydrolase gene
The present invention is to provide a gene having asymmetric hydrolase activity which is useful for synthesis of an optically active carboxylic acid, its antipode ester, and lactone, and a...
|
|
|
7332312 |
Carbonyl reductase, gene thereof and use of the same
The present invention provides a novel polypeptide forming (R)-2-chloro-1-(3′-chlorophenyl)ethanol, a polynucleotide coding for said polypeptide, and use of the same. The present invention...
|
|
|
7329519 |
Glucose dehydrogenase β subunit and DNA encoding the same
A DNA fragment encoding a β subunit is obtained by inverse PCR using primers designed based on the nucleotide sequnece of a N-terminal signal sequence region of a GDH β subunit derived from ...
|
|
|
7314734 |
Muteins of placental growth factor type 1, preparation method and application thereof
The present invention relates to chemically stable muteins of type 1 Placental Growth Factor (PLGF-1) bearing the substitution or elimination of a cysteine residue from the wild type protein amino...
|
|
|
7314733 |
Saitohin gene and uses of same
The present invention provides an isolated nucleic acid sequence encoding saitohin (STH), an isolated nucleic acid sequence that hybridizes to said sequence, and a purified protein encoded by said...
|
|
|
7309599 |
Aerobic fermentation method
A method and apparatus for effectively aerating large-scale cultures of microorganisms is disclosed.
|
|
|
7303906 |
Competent bacteria
The present invention discloses that a bacterium having a genome that is genetically engineered to be at least 10% smaller than the genome of its native parent strain has better transformation...
|
|
|
7294494 |
Nucleic acids encoding mutants of MAW motifs of RecA protein homologs
RecA protein mutants and RecA homolog protein mutants which contain one or more mutations in the MAW motif are presented. The mutants rely on replacement of wildtype amino acid residues in the MAW...
|
|
|
7285384 |
Parallel genotyping of multiple patient samples
The present invention relates to parallel genotyping (or other sample analysis) of multiple patients by direct sample immobilization onto microspheres of an array. The patient beads can then be...
|
|
|
7268215 |
Photoprotein derived from okinawan squid and gene encoding the photoprotein
By using a bioluminescence, a method for detection of a monovalent cation is provided and the method is a high sensitive and simple method. According to the present invention, an amino acid...
|
|
|
7262056 |
Enhancing intermolecular integration of nucleic acids using integrator complexes
We disclose compositions and processes for enhancing transposon mediated integration of a nucleic acid molecule into another target nucleic acid molecule. Integration by an integrator complex is...
|
|
|
7241572 |
Method for isolating and purifying nucleic acids
A method for isolating and purifying nucleic acids with an improved recovery yield is provided. A mixed solution containing the nucleic acids, salts, and an organic solvent is contacted with an...
|
|
|
7227010 |
Recombinant light chains of botulinum neurotoxins and light chain fusion proteins for use in research and clinical therapy
Botulinum neurotoxins, the most potent of all toxins, induce lethal neuromuscular paralysis by inhibiting exocytosis at the neuromuscular junction. The light chains (LC) of these dichain...
|
|
|
7226767 |
Process for producing cytidine diphosphate choline
A substantially pure culture of a microorganism having enzyme activities of pyrG and CCT and carrying a recombinant DNA composed of a DNA fragment containing genes encoding pryG and CCT and a vector.
|
|
|
7195897 |
Feedback-resistant homoserine transsuccinylases having a modified c-terminus
The invention relates to a homoserine transsuccinylase, which exhibits reduced sensitivity towards L-methionine or SAM in comparison with a homoserine transsuccinylase wild-type enzyme, whereby the...
|
|
|
7189557 |
Process for the intracellular over-production of streptokinase using genetically engineered strain of E. coli
An improved process for the production of streptokinase using a genetically engineered strain of Escherichia coli which overproduces streptokinase intracellularly and more particularly, the...
|
|
|
7183098 |
Loline alkaloid gene clusters of the fungal endophyte neotyphodium uncinatum
Loline alkaloids (LA), which are 1-aminopyrrolizidines with an oxygen bridge, are produced by Epichloë (anamorph= Neotyphodium ) species, endophytes of grasses. LA are insecticidal, thus helping...
|
|
|
7175997 |
BMP-11 compositions
Purified BMP-11 proteins and processes for producing them are disclosed. Recombinant DNA molecules encoding the BMP-11 proteins are also disclosed. The proteins may be useful in regulating follicle...
|
|
|
7163820 |
Escherichia coli strain for an oral vaccine against post-weaning diarrhea in pigs
The invention relates to a strain suitable for producing a live, orally applicable Escherichia coli vaccine for the prevention of post-weaning diarrhoea in pigs, and the procedure suitable for...
|
|
|
7163819 |
Bacterial hemoglobin genes and their use to increase carotenoid production
Genes encoding bacterial oxygen binding proteins are provided. Recombinant expression of at least one of the present bacterial hemoglobin genes increased the growth characteristics and/or...
|
|
|
7160680 |
Mutation analysis by mass spectrometry using photolytically cleavable primers
The invention relates to a method of a mass-spectrometric analysis of known mutation sites in the genome, such as single nucleotide polymorphisms (SNPs), using the method of restricted primer...
|
|
|
7153676 |
Transacylases of the paclitaxel biosynthetic pathway
Transacylase enzymes and the use of such enzymes to produce paclitaxel, related taxoids, as well as intermediates in the paclitaxel biosynthetic pathway are disclosed. Also disclosed are nucleic...
|
|
|
7144724 |
Process for the production of L-amino acids by fermentation using coryneform bacteria
A process for the production of an L-amino acid wherein coryneform bacteria (e.g. Coryneform glutamicum ) in which expression of the mqo gene coding for malate quinone oxidoreductase is attenuated...
|
|
|
7144699 |
Iterative resequencing
The invention provides iterative methods of analyzing a target nucleic acid that represents a variant of a reference nucleic acid. An array of probes is designed to be complementary to an estimated...
|
|
|
7132283 |
PRO273 polypeptides
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid...
|
|
|
7122375 |
PRO274 nucleic acids
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid...
|
|
|
7118884 |
Method for controlling metallophosphate precipitation in high cell density fermentations
The invention relates to the use of a phosphate glass as a phosphorus source in the media of high cell density bacterial fermentation processes in order to reduce metallophosphate precipitation...
|
|
|
7115725 |
Multi-mutant diphtheria toxin vaccines
Disclosed is DNA encoding diphtheria toxin polypeptides having multiple mutations, which render the polypeptides useful as vaccines.
|
|
|
7115229 |
Apparatus and method for monitoring molecular species within a medium
Apparatus and methods for monitoring, analyzing, and/or discriminating molecular species, preferably a biomolecule, within a medium using a multisensor array (MSA) and multivariate processing....
|
|
|
7112428 |
Chlorohydrin and hydroxycarboxylic ester asymmetric hydrolase gene
The present invention is to provide a gene having asymmetric hydrolase activity which is useful for synthesis of an optically active carboxylic acid, its antipode ester, and lactone, and a...
|
|
|
7094569 |
Hair follicle growth factor proteins
The present invention relates to novel hair follicle growth factor (HFGF) proteins, genes encoding HFGFs, methods for preparing HFGF proteins and therapeutic uses of HFGF proteins. The HFGF...
|
|
|
7094531 |
Nucleic acid sequencing
Provided is a method for sequencing DNA, which comprises: (a) obtaining a target DNA population comprising one or more single-stranded DNAs to be sequenced, each of which is present in a unique...
|
|
|
7090998 |
Method for producing target substance by fermentation
In a method for producing a target substance utilizing a microorganism, which comprises culturing a γ-proteobacterium in a medium to produce and accumulate the target substance in the medium or...
|
|
|
7083794 |
Recombinant vaccines comprising immunogenic attenuated bacteria having RpoS positive phenotype
Attenuated immunogenic bacteria having an RpoS + phenotype, in particular, Salmonella enterica serotype Typhi having an RpoS + phenotype and methods therefor are disclosed. The Salmonella ...
|
|
|
7078220 |
Highly transformable bacterial cells and methods for producing the same
The invention provided herein includes novel gram negative bacteria cells containing the Hte mutation. Other aspects of the invention include methods for rendering gram negative bacterial cells...
|
|
|
7078191 |
Composition and method for the detection of diseases associated with amyloid-like fibril or protein aggregate formation
The present invention relates to novel compositions useful for elucidating the onset or progress of diseases such as Huntington's disease, that are associated with the formation of fibrils or...
|
|
|
7070944 |
System for screening fatty acid transport inhibitors, methods of use and modulators identified thereby
Methods for identifying modulators of fatty acid transport and/or uptake, comprising contacting, under conditions favorable for fatty acid uptake, a putative modulator, e.g., an inhibitor with a...
|
|
|
7067300 |
Process for the biological production of 1,3-propanediol with high titer
The present invention provides an improved method for the biological production of 1,3-propanediol from a fermentable carbon source in a single microorganism. In one aspect of the present...
|
|
|
7067289 |
Method for producing histidine by fermentation with E. coli
The present invention provides a method for producing an amino acid selected from the group consisting of L-alanine, L-valine, L-leucine, L-isoleucine, L-methionine, L-phenylalanine, L-proline,...
|
|
|
7060436 |
Nucleic acid accessible hybridization sites
The present invention relates to methods and compositions for analyzing nucleic acids, and in particular, methods and compositions for detection and characterization of nucleic acid sequences and...
|
|
|
7053197 |
Ketogulonigenium endogenous plasmids
The present invention relates, in general, to a genus of bacteria known as Ketogulonigenium . The present invention further relates to transformed Ketogulonigenium , and methods of transforming ...
|
|
|
7053196 |
Ketogulonigenium endogenous plasmids
The present invention relates, in general, to a genus of bacteria known as Ketogulonigenium. The present invention further relates to transformed Ketogulonigenium, and methods of transforming ...
|
|
|
7052884 |
L-arginine producing Escherichia coli and method of producing L-arginine
Arginine can be efficiently produced by cultivating Escherichia coli which has an ability to produce arginine and an ability to utilize acetate in a culture medium to produce and accumulate...
|
|
|
7048915 |
Composition for cell-free protein synthesis
The present invention provides a composition for cell-free protein synthesis, which is superior in storage stability in a freeze-dried state, more particularly a freeze-dryable or freeze-dried...
|