Matches 1 - 50 out of 352 1 2 3 4 5 6 7 8 >
Match Document Document Title
7309599 Aerobic fermentation method  
A method and apparatus for effectively aerating large-scale cultures of microorganisms is disclosed.
7303906 Competent bacteria  
The present invention discloses that a bacterium having a genome that is genetically engineered to be at least 10% smaller than the genome of its native parent strain has better transformation...
7294494 Nucleic acids encoding mutants of MAW motifs of RecA protein homologs  
RecA protein mutants and RecA homolog protein mutants which contain one or more mutations in the MAW motif are presented. The mutants rely on replacement of wildtype amino acid residues in the MAW...
7285384 Parallel genotyping of multiple patient samples  
The present invention relates to parallel genotyping (or other sample analysis) of multiple patients by direct sample immobilization onto microspheres of an array. The patient beads can then be...
7268215 Photoprotein derived from okinawan squid and gene encoding the photoprotein  
By using a bioluminescence, a method for detection of a monovalent cation is provided and the method is a high sensitive and simple method. According to the present invention, an amino acid...
7262056 Enhancing intermolecular integration of nucleic acids using integrator complexes  
We disclose compositions and processes for enhancing transposon mediated integration of a nucleic acid molecule into another target nucleic acid molecule. Integration by an integrator complex is...
7250274 IL-21 production in prokaryotic hosts  
The expression vectors and methods using an E. coli expression system for the large scale production of IL-21 are described. The vectors utilize the IL-21 coding sequence with specific changes in...
7241572 Method for isolating and purifying nucleic acids  
A method for isolating and purifying nucleic acids with an improved recovery yield is provided. A mixed solution containing the nucleic acids, salts, and an organic solvent is contacted with an...
7227010 Recombinant light chains of botulinum neurotoxins and light chain fusion proteins for use in research and clinical therapy  
Botulinum neurotoxins, the most potent of all toxins, induce lethal neuromuscular paralysis by inhibiting exocytosis at the neuromuscular junction. The light chains (LC) of these dichain...
7226767 Process for producing cytidine diphosphate choline  
A substantially pure culture of a microorganism having enzyme activities of pyrG and CCT and carrying a recombinant DNA composed of a DNA fragment containing genes encoding pryG and CCT and a vector.
7195897 Feedback-resistant homoserine transsuccinylases having a modified c-terminus  
The invention relates to a homoserine transsuccinylase, which exhibits reduced sensitivity towards L-methionine or SAM in comparison with a homoserine transsuccinylase wild-type enzyme, whereby the...
7189557 Process for the intracellular over-production of streptokinase using genetically engineered strain of E. coli  
An improved process for the production of streptokinase using a genetically engineered strain of Escherichia coli which overproduces streptokinase intracellularly and more particularly, the...
7183098 Loline alkaloid gene clusters of the fungal endophyte neotyphodium uncinatum  
Loline alkaloids (LA), which are 1-aminopyrrolizidines with an oxygen bridge, are produced by Epichloë (anamorph= Neotyphodium ) species, endophytes of grasses. LA are insecticidal, thus helping...
7175997 BMP-11 compositions  
Purified BMP-11 proteins and processes for producing them are disclosed. Recombinant DNA molecules encoding the BMP-11 proteins are also disclosed. The proteins may be useful in regulating follicle...
7163820 Escherichia coli strain for an oral vaccine against post-weaning diarrhea in pigs  
The invention relates to a strain suitable for producing a live, orally applicable Escherichia coli vaccine for the prevention of post-weaning diarrhoea in pigs, and the procedure suitable for...
7163819 Bacterial hemoglobin genes and their use to increase carotenoid production  
Genes encoding bacterial oxygen binding proteins are provided. Recombinant expression of at least one of the present bacterial hemoglobin genes increased the growth characteristics and/or...
7160680 Mutation analysis by mass spectrometry using photolytically cleavable primers  
The invention relates to a method of a mass-spectrometric analysis of known mutation sites in the genome, such as single nucleotide polymorphisms (SNPs), using the method of restricted primer...
7153676 Transacylases of the paclitaxel biosynthetic pathway  
Transacylase enzymes and the use of such enzymes to produce paclitaxel, related taxoids, as well as intermediates in the paclitaxel biosynthetic pathway are disclosed. Also disclosed are nucleic...
7144724 Process for the production of L-amino acids by fermentation using coryneform bacteria  
A process for the production of an L-amino acid wherein coryneform bacteria (e.g. Coryneform glutamicum ) in which expression of the mqo gene coding for malate quinone oxidoreductase is attenuated...
7144699 Iterative resequencing  
The invention provides iterative methods of analyzing a target nucleic acid that represents a variant of a reference nucleic acid. An array of probes is designed to be complementary to an estimated...
7132283 PRO273 polypeptides  
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid...
7122375 PRO274 nucleic acids  
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid...
7118884 Method for controlling metallophosphate precipitation in high cell density fermentations  
The invention relates to the use of a phosphate glass as a phosphorus source in the media of high cell density bacterial fermentation processes in order to reduce metallophosphate precipitation...
7115725 Multi-mutant diphtheria toxin vaccines  
Disclosed is DNA encoding diphtheria toxin polypeptides having multiple mutations, which render the polypeptides useful as vaccines.
7115229 Apparatus and method for monitoring molecular species within a medium  
Apparatus and methods for monitoring, analyzing, and/or discriminating molecular species, preferably a biomolecule, within a medium using a multisensor array (MSA) and multivariate processing....
7112428 Chlorohydrin and hydroxycarboxylic ester asymmetric hydrolase gene  
The present invention is to provide a gene having asymmetric hydrolase activity which is useful for synthesis of an optically active carboxylic acid, its antipode ester, and lactone, and a...
7094569 Hair follicle growth factor proteins  
The present invention relates to novel hair follicle growth factor (HFGF) proteins, genes encoding HFGFs, methods for preparing HFGF proteins and therapeutic uses of HFGF proteins. The HFGF...
7094531 Nucleic acid sequencing  
Provided is a method for sequencing DNA, which comprises: (a) obtaining a target DNA population comprising one or more single-stranded DNAs to be sequenced, each of which is present in a unique...
7090998 Method for producing target substance by fermentation  
In a method for producing a target substance utilizing a microorganism, which comprises culturing a γ-proteobacterium in a medium to produce and accumulate the target substance in the medium or...
7083794 Recombinant vaccines comprising immunogenic attenuated bacteria having RpoS positive phenotype  
Attenuated immunogenic bacteria having an RpoS + phenotype, in particular, Salmonella enterica serotype Typhi having an RpoS + phenotype and methods therefor are disclosed. The Salmonella ...
7078220 Highly transformable bacterial cells and methods for producing the same  
The invention provided herein includes novel gram negative bacteria cells containing the Hte mutation. Other aspects of the invention include methods for rendering gram negative bacterial cells...
7078191 Composition and method for the detection of diseases associated with amyloid-like fibril or protein aggregate formation  
The present invention relates to novel compositions useful for elucidating the onset or progress of diseases such as Huntington's disease, that are associated with the formation of fibrils or...
7070944 System for screening fatty acid transport inhibitors, methods of use and modulators identified thereby  
Methods for identifying modulators of fatty acid transport and/or uptake, comprising contacting, under conditions favorable for fatty acid uptake, a putative modulator, e.g., an inhibitor with a...
7067300 Process for the biological production of 1,3-propanediol with high titer  
The present invention provides an improved method for the biological production of 1,3-propanediol from a fermentable carbon source in a single microorganism. In one aspect of the present...
7067289 Method for producing histidine by fermentation with E. coli  
The present invention provides a method for producing an amino acid selected from the group consisting of L-alanine, L-valine, L-leucine, L-isoleucine, L-methionine, L-phenylalanine, L-proline,...
7060436 Nucleic acid accessible hybridization sites  
The present invention relates to methods and compositions for analyzing nucleic acids, and in particular, methods and compositions for detection and characterization of nucleic acid sequences and...
7053197 Ketogulonigenium endogenous plasmids  
The present invention relates, in general, to a genus of bacteria known as Ketogulonigenium . The present invention further relates to transformed Ketogulonigenium , and methods of transforming ...
7053196 Ketogulonigenium endogenous plasmids  
The present invention relates, in general, to a genus of bacteria known as Ketogulonigenium. The present invention further relates to transformed Ketogulonigenium, and methods of transforming ...
7052884 L-arginine producing Escherichia coli and method of producing L-arginine  
Arginine can be efficiently produced by cultivating Escherichia coli which has an ability to produce arginine and an ability to utilize acetate in a culture medium to produce and accumulate...
7048915 Composition for cell-free protein synthesis  
The present invention provides a composition for cell-free protein synthesis, which is superior in storage stability in a freeze-dried state, more particularly a freeze-dryable or freeze-dried...
7045324 Tocopherol associated protein and uses thereof  
The present invention provides a novel tocopherol associated protein (TAP-38) DNA/protein with a 76 nucleotide base deletion resulting in a 25 amino acid deletion, followed by 90 novel nucleotides...
7045320 Methods for producing L-amino acids  
A bacterium belonging to the genus Escherichia having an ability to produce an L-amino acid is cultured in a medium containing fructose as a main carbon source, preferably a medium containing a...
7033772 Methods of identifying inhibitors of fatty acid transport proteins (FATP)  
A family of fatty acid transport proteins (FATPs) mediate transport of long chain fatty acids (LCFAs) across cell membranes into cells. These proteins exhibit different expression patterns among...
7030233 Ketogulonigenium endogeneous plasmids  
The present invention relates, in general, to a genus of bacteria known as Ketogulonigenium . The present invention further relates to transformed Ketogulonigenium , and methods of transforming ...
7018629 Probiotic compositions for the treatment of inflammatory bowel disease  
Pharmaceutical compositions of probiotic E. coli strains and uses thereof for treating inflammatory bowel disease.
7008651 E. coli extract for protein synthesis  
There is now a market for kits containing the necessary components for performing protein synthesis reactions using template DNA of the experimenter. One category of existing system for performing...
7001721 Nucleic acid sequence identification  
Disclosed are methods for determining the presence or absence of a target nucleic acid (e.g. DNA) sequence in a sample nucleic acid, the method comprising: (a) exposing the sample to a detection...
6998231 Typing and diagnosis of spongiform encephalopathy  
The present invention relates to a method for typing a sample of a prion or spongiform encephalopathy disease, a kit suitable for use in such a typing method, a method for identifying infection in...
6994960 Nucleic acid diagnostics based on mass spectrometry or mass separation and base specific cleavage  
A method of detecting a mutation or a difference of one or more nucleotides between a nucleic acid molecule to be tested and a reference nucleic acid molecule, said method comprising subjecting the...
6989265 Bacteria with reduced genome  
The present invention provides a bacterium having a genome that is genetically engineered to be at least 2 to 14% smaller than the genome of its native parent strain. A bacterium with a smaller...
Matches 1 - 50 out of 352 1 2 3 4 5 6 7 8 >