Matches 51 - 100 out of 352 < 1 2 3 4 5 6 7 8 >
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6987176 Combinant polypeptide for use in the manufacture of vaccines against Campylobacter induced diarrhea and to reduce colonization  
This invention comprises a recombinant protein comprising the maltose binding protein (MBP) of Escherichia coli fused to amino acids 5–337 of the FlaA flagellin of Campylobacter coli VC167...
6986985 Process for producing multiple nucleic acid copies in vivo using a protein-nucleic acid construct  
This invention provides in vitro processes for producing copies of specific nucleic acids using protein-nucleic acid constructs which are part of conjugates which are introduced into cells....
6984514 Bacterium having ability to produce L-glutamic acid, L-proline or L-arginine and method for producing L-glutamic acid, L-proline or L-arginine  
L-Glutamic acid, L-proline or L-arginine is produced by culturing a bacterium belonging to the genus Escherichia, which is L-isoleucine auxotrophic and has ability to produce L-glutamic acid,...
6982147 Apparatus for assaying biopolymer binding by means of multiple measurements under varied conditions  
An apparatus for assaying specific binding of a probe to a target, includes: a sample support; a light source; an optical train; a light detector; an electricity source; an electrical property...
6974670 Method of synthesizing nucleic acid  
The present invention relates to an oligonucleotide having a novel structure and a method of synthesizing nucleic acid by using the same as a primer. This oligonucleotide is provided at the...
6969587 Detection of nucleic acid heteroduplex molecules by anion-exchange chromatography  
The present invention describes a method for separating or partially separating heteroduplex and homoduplex DNA molecules in a mixture. In the method, the mixture is applied to an anion-exchange...
6964847 Derivative nucleic acids and uses thereof  
The invention features a method for multiplexed analysis of a plurality of target nucleic acid sequences in a sample. The method provides a derivative nucleic acid for each target sequence analyzed...
6962807 Descendants of bacteria devoid of N terminal formylation useful for the production of proteins and peptides  
The present invention relates to producing non-formylated proteins and/or peptides in bacterial cells lacking deformylase and/or transformylase.
6962795 Neutrophil inhibitors  
Compositions enriched for Neutrophil Inhibitory Factor which inhibit neutrophil activity including adhesion to vascular endothelial cells are provided. Also provided are recombinant Neutrophil...
6962696 Compositions and methods for tumor-targeted delivery of effector molecules  
The present application discloses the preparation and use of attenuated tumor-targeted bacteria vectors for the delivery of one or more primary effector molecule(s) to the site of a solid tumor....
6960464 Methods for lyophilizing competent cells  
This invention relates to a method for producing cells which are competent for transformation and which may be stably stored for extended periods of time at various temperatures. The method...
6958215 Methods and compositions for inhibition of RNA splicing  
A method of inhibiting the self-splicing of a Group I intron is disclosed. The method uses an oligonucleotide having a sequence essentially identical to a guide sequence found in the 5′ flanking...
6955892 Feeding processes for fermentation  
Embodiments of the present invention generally relate to novel fed-batch fermentations wherein processes of DO-stat and pH-stat are combined for nutrient feeding control.
6949383 Mutagenesis method  
This application provides a method for mutagenesis of a gene, which comprises introducing much more point mutations into one strand of double-stranded genomic DNA of cell or organism individual...
6943028 Regulator/promoter for tunable gene expression and metabolite sensing  
A method for the facile and inexpensive inducible expression of heterologous genes has been discovered. The yhcS regulator gene has been found to be inducible by aromatic carboxylic acids and to...
6942996 Isolated polynucleotide from Corynebacterium encoding a homocysteine methyltransferase  
An isolated polynucleotide comprising a polynucleotide sequence selected from the group consisting of a) polynucleotide which is at least 70% identical to a polynucleotide that codes for a...
6929947 Secreted and transmembrane polypeptides and nucleic acids encoding the same  
The present invention is directed to nucleic acids encoding a secreted polypeptide that inhibits neoplastic growth in tumor cells. Also provided herein are vectors and host cells comprising those...
6924109 High-throughput transcriptome and functional validation analysis  
Methods for correlating genes and gene function are provided. Such methods generally involve selecting a candidate gene that appears to be correlated with a particular cellular state or activity...
6924107 Four dimensional biochip design for high throughput applications and methods of using the four dimensional biochip  
The present invention provides a 4D biochip containing m 3D biochips having n capillaries, wherein the n capillaries each contain a biological factor, and methods for preparing and using the 4D...
6923972 Methods for use of genetically modified tumor-targeted bacteria with reduced virulence  
The present invention is directed to mutant Salmonella sp. having a genetically modified msbB gene in which the mutant Salmonella is capable of targeting solid tumors. The present invention...
6921640 Process for labeling a ribonucleic acid  
The present invention relates to a process for labeling a synthetic or natural ribonucleic acid (RNA). It also relates to RNA fragments, which have been labeled by fragmenting the RNA to free a...
6919175 System for releasing and isolating nucleic acids  
A procedure for the release and isolation of nucleic acids from biological compartments of a sample always uses an instrument that can hold one or more sample processsing vessels, maintain the...
6916646 Enterobacteriaceae fermentation strains  
Methods are provided for preparing improved fermentation strains of the family Enterobacteriaceae which comprise the steps of eliminating the cryptic plasmid from the progenitor strain thereby...
6916613 Compositions, methods, kits and apparatus for determining the presence or absence of target molecules  
The present invention is directed to methods, compositions, kits and apparatus to identify and detect the presence or absence of target analytes. The embodiments of the present invention have...
6913880 Method for determining transcription factor activity and its technical uses  
Certain transcription factors (enhancer binding proteins) significantly increase transcription rates from genes by nicking a single DNA strand in the vicinity of their DNA binding sites, thereby...
6905866 Sigma binding region of RNA polymerase and uses thereof  
The invention provides cells expressing the sigma binding region of the β′ subunit of RNA polymerase and a method to identify inhibitors of the formation of holoenzyme from core RNA polymerase...
6905825 Method for isolating and purifying nucleic acids  
A method for isolating and purifying nucleic acids with an improved recovery yield is provided. A mixed solution containing the nucleic acids, salts, and an organic solvent is contacted with an...
6905823 Cellular arrays and methods of detecting and using genetic disorder markers  
A method is disclosed for rapid molecular profiling of tissue or other cellular specimens by placing a donor specimen in an assigned location in a recipient array, providing copies of the array,...
6905817 Ret-independent signaling pathway for GDNF  
Methods for screening for agonists and antagonists of GPI-anchored independent intracellular signaling resulting in [Ca 2+ ] i elevation, ERK1, ERK2 and CREB phosphorylation, and Src family kinase...
6902906 Bacteria attenuated by a non-reverting mutation in each of the aroC, ompF and ompC genes, useful as vaccines  
The invention provides a bacterium attenuated by a non-reverting mutation in each of the aroC gene, the ompF gene and the ompC gene. The bacterium is useful as a vaccine. The bacterium may, for...
6893860 Microorganisms and methods for producing threonine  
The present invention relates to methods and microorganisms for producing L-threonine. In particular, the present invention relates to the production of L-threonine using microorganisms, and ...
6893821 Agents that modulate DNA-PK activity and methods of use thereof  
The present invention provides methods for modulating cell death in a eukaryotic cell, and methods for reducing DNA damage in a eukaryotic cell. The methods generally comprise modulating a...
6866847 Method of delivering a protein to poultry  
A method of delivering a protein to domestic poultry by administering to the poultry by whole body spray an effective amount of a live avirulent derivative of an enteropathogenic bacterium that...
6863894 Genetically modified tumor-targeted bacteria with reduced virulence  
The present invention is directed to mutant Salmonella sp. having a genetically modified msbB gene in which the mutant Salmonella is capable of targeting solid tumors. The invention is also...
6861247 Salmonella secreted proteins and uses thereof  
Substantially pure Salmonella secreted proteins (Ssp), the sercetion of which is dependent upon the expession of PrgH; methods of diagnosing Salmonella infection; and live attenuated vaccine...
6852512 Expression vectors for production of foreign proteins as soluble forms  
The present invention relates to novel expression vectors which can produce foreign proteins as soluble forms by using lysyl-tRNA synthetase and a process for preparing foreign proteins by using...
6849593 Bifidogenic peptides  
Pepetides having bifidogenic properties are obtainable by the process of adding proteases to cow'milk or human milk, followed by incubation, centrifugation, acidification, purification by reverse...
6841365 L-arginine producing Escherichia coli and method of producing L-arginine  
Arginine can be efficiently produced by cultivating Escherichia coli which has an ability to produce arginine and an ability to utilize acetate in a culture medium to produce and accumulate...
6833130 Recombinant microorganisms expressing an oligosaccharide receptor mimic  
Chimeric carbohydrates produced by recombinant microorganism carrying exogenous glycosyltransferases act with or without exogenous enzymes required for synthesis or nucleotide synthesis precursors....
6821755 Preparation of a recombinant protein in a prokaryotic host cell  
The invention relates to advantageous processes for preparing heterologous proteins in prokaryotic host cells by improved codon use and/or expression of tRNAs which code for codons occurring rarely...
6818395 Methods and apparatus for analyzing polynucleotide sequences  
Methods for high speed, high throughput analysis of polynucleotide sequences, and apparatuses with which to carry out the methods are provided in the invention.
6806047 Methods and compositions for amplifying detectable signals in specific binding assays  
Methods and compounds are provided for detecting target molecules in a sample using specific binding assays. In particular, methods are provided for detecting a nucleic acid target in a sample. In...
6783935 Genetic polymorphism of MxA protein and use thereof  
The present invention provides polynucleotides having base sequences of sequence Nos. 1 to 4, as polynucleotides having polymorphism sites capable of being useful indicators for prediction of...
6774213 Mutants of MAW motifs of RecA protein homologs, methods of making them, and their uses  
RecA protein mutants and RecA homolog protein mutants which contain one or more mutations in the MAW motif are presented. The mutants rely on replacement of wildtype amino acid residues in the MAW...
6770457 Process of purifying angiogenesis inhibitors  
The present invention relates to process of purifying the angiogensis inhibitor proteins expressed in E. coli and to the use of recombinant kringle 1-3 (; greenstatin) purified by the above...
6770443 Method and apparatus for mass spectrometric genotyping  
Methods and equipment are provided for the mass spectrometric measurement of a large number of genotyping profiles, each formed by several tens to several hundreds of SNPs (single nucleotide...
6759524 Photoprotein derived from okinawan squid and gene encoding the photoprotein  
By using a bioluminescence, a method for detection of a monovalent cation is provided and the method is a high sensitive and simple method. According to the present invention, an amino acid...
6756222 Escherichia coli having accession No. PTA 1579 and its use to produce polyhydroxybutyrate  
The present invention provides a novel genetically modified Escherichia coli JM109 bearing accession number PTA 1579, containing the gene coding for poly-beta-hydroxybutyrate synthesis and a...
6753145 Buffer composition and method for hybridization of microarrays on adsorbed polymer siliceous surfaces  
A buffer composition, method and kit for hybridizing microarrays of nucleic acids bound to an adsorbed polymer surface of a siliceous substrate provide an envelope of conditions to hybridize...
6750022 Mutation analysis by PCR and mass spectrometry  
The invention concerns mass spectrometric analysis of known mutation sites in the genome, such as single nucleotide polymorphisms (SNPs). The invention uses minor amounts of primers with...
Matches 51 - 100 out of 352 < 1 2 3 4 5 6 7 8 >