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7309600 Haemophilus influenzae sialyltransferase and methods of use thereof  
The present invention is directed to sialytransferases, such as SiaA sialytransferases isolated from Haemophilus influenzae . Further provided herein are methods for producing sialylated...
7306933 Method for producing L-lysine or L-threonine  
A bacterium belonging to the genus Escherichia which has an ability to produce L-lysine or L-threonine and which is modified so that a malic enzyme does not function normally in a cell, and a...
7303906 Competent bacteria  
The present invention discloses that a bacterium having a genome that is genetically engineered to be at least 10% smaller than the genome of its native parent strain has better transformation...
7303894 Detection of phenols using engineered bacteria  
Detection of phenols using engineered bacteria. A biosensor can be created by placing a reporter gene under control of an inducible promoter. The reporter gene produces a signal when a cognate...
7300786 Bacteria of the Enterobacteriaceae family having enhanced transaldolase activity  
A method is provided for producing L-histidine using bacterium of the Enterobacteriaceae family, wherein the L-amino acid productivity of said bacterium is enhanced by enhancing an activity of the...
7300776 L-amino acid-producing bacterium and a method for producing L-amino acid  
An L-amino acid-producing strain of Escherichia coli is bred by modifying an Escherichia coli K12 strain or a derivative thereof so as to become resistant to L-valine and have an ability to...
7294491 Method for producing L-glutamic acid  
The present invention provides a method for producing L-glutamic acid by fermentation, by culturing in a liquid medium a microorganism that can metabolize a carbon source at a specific pH, and...
7291495 β-Secretase variant  
The invention provides polynucleotides and polypeptides encoding an isolated amyloid inhibitor protein (APIP) and compositions thereof. The polypeptides of the subject invention can be used to...
7291490 Nucleic acid fragment encoding an NRPS for the biosynthesis of anthramycin  
Genes and proteins involved in the biosynthesis of benzodiazepines by microorganisms, including the genes and proteins forming the biosynthetic loci for the benzodiazepine anthramycin from ...
7291486 Genetically modified cells and methods for converting (R)-methylmalonyl CoA to (S)-methylmalonyl CoA  
Recombinant Escherichia coli host cells that comprise recombinant DNA expression vectors that drive expression of methylmalonyl CoA mutase from Propionibacterium shermanii or Streptomyces...
7291482 Mutations affecting plasmid copy number  
Mutations in chromosomal genes have been identified that affect plasmid copy number in plasmids that are anti-sense RNA regulated such as the pMB1-derived and p15A-derived plasmids.
7288402 Rhodococcus nitrile hydratase  
The invention relates to a Rhodococcus polynucleotide cluster which contains nucleotide sequences which encode polypeptides having the activity of a nitrile hydratase, of an auxiliary protein...
7288395 ACC gene  
The present invention relates to a gene useful in a process to increase the microbial production of carotenoids. The carotenoids astaxanthin is distributed in a wide variety of organisms such as...
7288393 Nucleotide sequence of threonine operon irrepressible by isoleucine and method for producing L-threonine using transformed host cell containing the same  
A nucleotide sequence of the threonine operon of E. coli with a deletion of all or part of a nucleotide fragment of −56 to −18, a recombinant vector containing the above nucleotide sequence,...
7285654 Stimulus-inducible protein kinase complex and methods of use therefor  
Compositions and methods are provided for treating NF-κB-related conditions. In particular, the invention provides a stimulus-inducible IKK signalsome, and components and variants thereof. An IKK...
7285406 Nucleic acid fragments encoding nitrile hydratase and amidase enzymes from Comamonas testosteroni 5-MGAM-4D and recombinant organisms expressing those enzymes useful for the production of amides and acids  
The invention relates to the isolation, sequencing, and recombinant expression of genes encoding either a nitrile hydratase (NHase) or amidase (Am) from Comamonas testosteroni 5-MGAM-4D, where...
7282579 Serine protease BSSP6  
There are provided a polynucleotide encoding human BSSP6 serine protease and a vector and transformed host cells containing this human BSSP6 serine protease encoding polynucleotide.
7282483 Method of ameliorating the harmful effects of TNF using a polypeptide having the ability to bind to TNF  
The present invention provides DNA sequences coding for a TNF-binding protein and for the TNF receptor of which this protein constitutes the soluble domain. The DNA sequences can be used for...
7282356 D-aminoacylase mutants  
The present invention provides mutant D-aminoacylases and use thereof. The mutant D-aminoacylases are hard to be inhibited by the substrate and, comprise the amino acid sequences of the...
7279321 Methods for increasing the resistance of a host cell to aromatic carboxylic acids  
The invention provides methods of increasing the production of aromatic carboxylic acids from a host cell via manipulation of the yhcRQP operon encoding a family of efflux proteins. Up-regulation...
7279313 Circular DNA molecule having a conditional origin of replication, process for their preparation and their use in gene therapy  
A circular DNA molecule, useful for gene therapy, comprising at least one nucleic acid sequence of interest, characterised in that the region allowing the replication thereof has an origin of...
7276363 Nucleic acid molecules encoding red and green emitting luciferases  
Isolated nucleic acid molecules which code for luciferases able to produce the green bioluminescence of Phrixotrhix vivianii and red bioluminescence of Phrixothrix hirtus are described. The...
7273743 Modified BACE  
The present invention relates to recombinant human BACE polypeptides. More particularly, the invention relates to recombinant human BACE polypeptides that have a modified amino acid sequence at...
7271005 Modulation of bacterial membrane permeability  
Nucleic acids and polypeptides involved in regulation of membrane permeability in bacteria are disclosed. Also disclosed are methods of increasing sensitivity to antibiotics in multi-drug resistant...
7268114 Protein and process for preparing the same  
A protein having amino acid sequence in SEQ ID NO: 1 of the Sequence Listing derived from human MP52, and a dimer protein thereof. A homodimer protein described above can be obtained by...
7262046 Aerobic succinate production in bacteria  
Methods of increasing yields of succinate using aerobic culture methods and a multi-mutant E. coli strain are provided. Also provided is a mutant strain of E. coli that produces high amounts of...
7262037 Method for the production of D-(-)-3-hydroxybutyric acid by recombinant Escherichia coli  
This invention relates to a method for the production of D-(−)-3-hydroxybutyric acid, comprising the step of culturing a recombinant strain containing genes phbA, phbB, ptb and buk by...
7262035 Method for producing L-glutamine by fermentation and L-glutamine producing bacterium  
L-Glutamine is produced by culturing a coryneform bacterium which has L-glutamine producing ability and has been modified so that its intracellular glutamine synthetase activity should be enhanced,...
7259003 Escherichia bacteria transformed with a yedA homolog to enhance L-amino acid producing activity, and methods for producing an L-amino acid using same  
A method for producing an L-amino acid, such as L-phenylalanine or L-threonine, is provided using a bacterium belonging to the genus Escherichia , wherein the L-amino acid productivity of said...
7256279 Protein having ribonucleotide reductase activity and DNA thereof  
A protein having ribonucleotide reductase activity, DNA encoding the protein, antibodies to these and the like are disclosed. The protein, DNA and antibodies are useful in the prevention, treatment...
7256021 Enterobacteriaceae strains with an attenuated aspA gene for the fermentative production of amino acids  
The invention relates to a process for the preparation of L-amino acids, especially L-lysine, L-valine, L-homoserine and L-threonine, by fermenting a microorganism of the genus Escherichia which...
7255855 Surface expression method of peptides P5 and Anal3 using the gene encoding poly-gamma-glutamate synthetase  
The present invention relates to a method for expressing each of peptide antibiotics P5 3 and Ana13 35 having amphiphilicity and showing antibacterial, antifungal and anticancer activities 61, 63,...
7252978 Method for producing L-arginine  
L-Arginine is produced by culturing a microorganism which has L-arginine producing ability and has been modified so that expression of lysE gene should be enhanced, such a microorganism further...
7252977 Nucleotide sequences which code for the msiK gene  
The invention relates to an isolated polynucleotide from Corynebacterium glutamicum having a polynucleotide sequence which encodes the sugar import protein K (msiK) gene, and a host-vector system...
7250280 Method of improving the production of biomass or a desired product from a cell  
The production of biomass or a desired product from a cell can be improved by inducing conversion of ATP to ADP without primary effects on other cellular metabolites or functions which is achieved...
7250261 EspFu nucleic acids and proteins and uses thereof  
Disclosed are EspF U (EspF-like polypeptide encoded by a gene of the cryptic prophage CP-933U of enterohemorrhagic E. coli ) polypeptides, fragments thereof, nucleic acids that encode EspF U ...
7247466 Amino acid racemase having low substrate specificity and process for producing racemic amino acid  
The present invention provides a protein having low-substrate-specific amino acid racemase activity; DNA encoding the protein; a recombinant DNA comprising the DNA; a transformant carrying the...
7247459 L-glutamic acid producing bacterium and process for producing L-glutamic acid  
L-glutamic acid is produced by culturing in a medium a microorganism belonging to enterobacteria and having L-glutamic acid productivity, into which a citrate synthase gene derived from a...
7247455 Streptococcus pyogenes DNase B leader peptide and methods for its use  
The gene for Streptococcus pyogenes DNase B has been cloned and vectors incorporating the cloned DNA have been used to transform Escherichia coli, allowing efficient and rapid production of the...
7247441 Nucleic acid sequence and protein in addition to polypeptides coding for mannitol dehydrogenases or parts thereof and the production and use thereof in diagnosis and therapy  
The invention relates to polypeptides made of mannitol-dehydrogenase of Cladosporium herbarum and Alternaria alternata nucleic acids coding therefor and the use thereof in diagnosis and therapy.
7244610 Aerobic succinate production in bacteria  
Methods of increasing yields of succinate using aerobic culture methods and a multi-mutant E. coli strain are provided. Also provided is a mutant strain of E. coli that produces high amounts of...
7244609 Synthetic genes and bacterial plasmids devoid of CpG  
The invention relates to a new series of bacterial plasmid vectors which are fully devoid of CpG and which can express synthetic genes which do not contain CpG in the bacteria Escherichia coli.
7244605 Polypeptides having beta-glucosidase activity and polynucleotides encoding same  
The present invention relates to isolated polypeptides having beta-glucosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid...
7244595 Method of maintaining or improving a nitrile hydratase activity  
The object of this invention is to provide a method which not only maintains the nitrile hydratase activity of a nitrile hydratase-containing cell or a treated material of the cell under conditions...
7244587 Expression vectors encoding bacteriophage signal peptides  
Expression vectors encoding bacteriophage signal peptides are described. The vectors may be used for the heterologous expression and secretion of polypeptides such as antibodies in bacterial host...
7244560 Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites  
The present invention provides compositions and methods for recombinational cloning. The compositions include vectors having multiple recombination sites and/or multiple topoisomerase recognition...
7238776 TNF binding proteins  
The present invention provides DNA sequences coding for a TNF-binding protein and for the TNF receptor of which this protein constitutes the soluble domain. The DNA sequences can be used for...
7238509 β 1,4-N-acetylgalactosaminyl transferases from C. jejuni  
This invention provides prokaryotic glycosyltransferases, including a bifunctional sialyltransferase that has both an α2,3- and an α2,8-activity. A β1,4-GalNAc transferase and a...
7238501 Process for producing trans-4-hydroxy-L-proline  
The present invention is directed to a process for producing trans-4-hydroxy-L-proline, which is useful as a raw material for medicines or as an additive to foods. In the process, L-proline is...
7238100 β1,3-galactosyltransferase and DNA encoding the same  
The present invention provides a protein having a β1,3-galactosyltransferase activity derived from a microorganism; a DNA encoding the protein; a recombinant DNA containing the DNA and a vector; a...
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