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7642080 |
Subtilases
The present invention relates to novel subtilases from wild-type strains of Bacillus , especially the Bacillus strains ZI344, EP655, P203, EP63, ZI120, ZI130, ZI1342 and ZI140, and to methods of...
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7604973 |
DNA encoding hyaluronan synthase from Pasteurella multocida and methods of use
The present invention relates to a nucleic acid segment having a coding region segment encoding enzymatically active Pasteurella multocida hyaluronate synthase (PmHAS), and to the use of this...
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7595185 |
Cytotoxin-based biological containment
Method of conditionally controlling the survivability of a recombinant cell population and of containing such cells to an environment or containing replicons to a host cell is based on the use of...
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7595186 |
Cytotoxin-based biological containment
Method of conditionally controlling the survivability of a recombinant cell population and of containing such cells to an environment or containing replicons to a host cell is based on the use of...
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7550281 |
Method for production of alpha-amylase in recombinant Bacillus
Disclosed is a novel recombinant Bacillus bacterial strain constructed by genetic engineering which has high productivity of aipha-amylase. The Bacillus strain comprises an alpha-amylase gene...
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7547536 |
Method for detecting bacterial spores
A method of detecting the presence and quantity of bacterial spores, which includes adding an electrophilic alcohol and an acid anhydride to a sample, admixing the sample with a solvent, and...
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7541173 |
Solvent tolerant microorganisms and methods of isolation
Lactobacillus bacteria having enhanced tolerance to butanols have been isolated. The bacteria are useful for the fermentive production of butanol. New methods for the isolation of butanol tolerant...
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7537922 |
Proteases and variants thereof
The present invention relates to isolated proteases of the RP-II type and variants of RP-II proteases exhibiting improved properties in comparison to the parent RP-II protease, DNA constructs and...
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7531345 |
Mutations for enhanced tyrosine production
The present invention provides cells genetically engineered to express mutated chorismate mutase/prephenate dehydrogenase (CM/PDH), the nucleic acid coding for each mutated CM/PDH and similar...
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7521204 |
Bacillus host cell
A Bacillus licheniformis mutant host cell derived from a parent B. licheniformis host cell, which mutant host cell is mutated in one or more gene(s) encoding one or more secreted polypeptide(s)...
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7521222 |
Farnesyl dibenzodiazepinone and processes for its production
This invention relates to a novel farnesylated dibenzodiazepinone, named ECO-04601, its pharmaceutically acceptable salts and derivatives, and to methods for obtaining such compounds. One method of...
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7510859 |
Subtilisin variants with improved perhydrolase activity
The invention relates to novel perhydrolases, derived from the protease Carlsberg by amino acid exchange in positions 11, 15, 21, 38, 50, 54, 58, 77, 83, 89, 93, 96, 107, 117, 120, 134, 135, 136,...
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7507402 |
Topical use of probiotic Bacillus spores to prevent or control microbial infections
Compositions including an isolated Bacillus species, spores or an extracellular product of B. coagulans , suitable for topical application, for inhibiting growth of yeast, fungus, bacteria or...
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7504236 |
Method to increase carotenoid production in a microbial host cell by down-regulating glycogen synthase
A method to increase carotenoid production in carotenogenic microbial host cells is provided by down-regulating or disrupting glycogen synthesis. Disruption of glycogen synthase activity in a...
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7501262 |
Promoters and gene expression method by using the promoters
To provide a promoter, a recombinant DNA, a gene expression vector, an expression vector, and a transformant, which are capable of expressing a gene without inducing gene expression with an...
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7494798 |
Bacillus licheniformis chromosome
The present invention relates to an isolated polynucleotide of the complete chromosome of Bacillus licheniformis . The present invention also relates to isolated genes of the chromosome of ...
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7491404 |
Acellular immunogenic compositions and acellular vaccine compositions against Bacillus anthracis
The invention concerns an acellular immunogenic or vaccine composition for producing antibodies against Bacillus anthracis comprising a protective antigen (PA) and killed and optionally purified...
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7485447 |
Proteases and methods for producing them
A secreted proteolytic polypeptide comprising at least three non-polar or uncharged polar amino acids within the last four amino acids of the C-terminus of the polypeptide, encoding...
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7476516 |
Methods for producing biological substances in pigment-deficient mutants of Bacillus cells
The present invention relates to methods of producing a heterologous biological substance, comprising: (a) cultivating a mutant of a parent Bacillus cell under conditions conducive for the...
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7470528 |
DNA encoding hydroxylase
The present invention relates to a protein derived from a microorganism belonging to the genus Bacillus , which has an activity of hydroxylating a compound represented by the formula (I-a):
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7442540 |
Polynucleotide encoding coleopteran-toxic polypeptide
Disclosed are novel insecticidal polypeptides, and compositions comprising these polypeptides, peptide fragments thereof, and antibodies specific therefor. Also disclosed are vectors, transformed...
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7422873 |
Mutant carotenoid ketolase
CrtW carotenoid ketolases are provided useful for the production of astaxanthin. The ketolases genes of the present invention exhibit improved ketolase activity when converting cyclic hydroxylated...
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7417135 |
Plasmidic gene, ways of acquiring this gene, the amylolytic enzyme it encodes and its application
The object of the invention is a novel plasmidic gene encoding an amylolytic enzyme which after introduction into a microbial strain, favorably bacterial, especially Lactococcus lactis , enables...
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7413877 |
Bacterial expression of bowman-birk protease inhibitors and variants thereof
The present invention provides compositions and methods related to the expression of Bowman-Birk protease inhibitors and variants thereof in bacterial species. The present invention further...
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7407791 |
Production of secreted polypeptides
Described herein are methods and compositions for the production and secretion of polypeptides. Included herein is the use of interrupting peptide transport activity for an increase in polypeptide...
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7399623 |
Modified forms of pullulanase
The present invention relates to modified pullulanases useful in the starch industry. The present invention provides methods for producing the modified pullulanase, enzymatic compositions...
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7393671 |
Mutant carotenoid ketolases
CrtW carotenoid ketolases are provided that are useful for the production of astaxanthin and other cyclic ketocarotenoids. The mutant ketolase genes of the present invention encode polypeptides...
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7378512 |
Production of proteins by autoproteolytic cleavage
The present invention relates to a process for the production of a heterologous polypeptide with homogeneous N-terminus in a bacterial host cell, wherein the heterologous polypeptide is...
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7364875 |
Method for producing medical and commercial grade poly-gamma-glutamic acid of high molecular weight
Methods for producing high molecular weight poly-gamma-glutamic acid (PGA). The PGA is produced by fermentation, and purified by use of tangential flow filtration, followed by diafiltration, as...
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7344855 |
Fermentation process
A process for the preparation of a target fermentation product comprising cultivation of an aerobic microorganism to produce such product, wherein in the microorganism the efficiency of the...
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7335506 |
Method for producing L-lysine or L-arginine by using methanol-assimilating bacterium
A DNA encoding a variant of a protein, the protein having a loop region and six hydrophobic helices and involved in secretion of L-lysine to the outside of a cell, wherein the DNA encodes a variant...
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7335505 |
Materials and methods relating to protein aggregation in neurodegenerative disease
The present invention provides methods of proteolytically converting a precursor protein (e.g. tau) to a product fragment (e.g., a 12 kd fragment) in a stable cell line, wherein the precursor...
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7329741 |
Polynucleotides that hybridize to DP-75 and their use
The present invention is a novel nucleic acid sequence which hybridizes to SEQ ID NO:6 or fragments thereof under stringent conditions, or fragments thereof. The invention also includes diagnostic...
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7326546 |
Purine-derived substance-producing bacterium and a method for producing purine-derived substance
A purine-derived substance is produced by culturing a Bacillus bacterium which has an ability to produce a purine-derived substance and has enhanced activity of an enzyme of the oxidative...
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7323328 |
Obligately symbiotic thermophile Symbiobacterium toebii SC-1 producing thermostable L-tyrosine phenol-lyase and L-tryptophan indole-lyase
The present invention relates to a novel obligately symbiotic thermophile Symbiobacterium toebii SC-1 (Accession NO: KCTC 0685BP), and a thermostable L-tyrosine phenol-lyase and L-tryptophan...
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7319030 |
Non-sporulating Bacillus subtilis having parts of the gene encoding sigma G deleted
A non-sporulating Bacillus subtilis strain, a method for preparing it and its use as a production organism. A method for preparing a biologically prepared product with the non-sporulating...
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7319028 |
Process for producing sporangia of Bacillus popilliae, control agent, and controlling method
The present invention provides a process for efficiently producing sporangia of Bacillus popilliae containing spores and parasporal bodies having controlling effects on Scarabaeidae insects,...
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7316924 |
Twin-arginine translocation in Bacillus
Described herein are methods to enhance protein secretion in a host cell. In preferred embodiment, the host cell is a gram-positive microorganism such as a Bacillus . In another preferred...
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7312066 |
Nucleic acid molecules encoding NRC interacting factor-1 (NIF-1)
The present invention relates to isolated human and rat nucleic acid molecules encoding a protein or polypeptide that modulates transcriptional activation in a cell with or without collaboration...
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7282356 |
D-aminoacylase mutants
The present invention provides mutant D-aminoacylases and use thereof. The mutant D-aminoacylases are hard to be inhibited by the substrate and, comprise the amino acid sequences of the...
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7250281 |
Subtilisin variants
Novel carbonyl hydrolase variants derived from the DNA sequences of naturally-occurring or recombinant non-human carbonyl hydrolases are disclosed. The variant carbonyl hydrolases, in general, are...
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7244581 |
Glucose dehydrogenase
Disclosed is a modified glucose dehydrogenase having pyrroloquinoline quinone as a coenzyme, wherein one or more amino acid residues in a region of amino acid 349-377 of water-soluble PQQGDH...
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7229796 |
Hyaluronan synthase genes and expression thereof in Bacillus hosts
The present invention relates to a recombinant Bacillus host cell containing a recombinant vector including a nucleic acid segment having a coding region segment encoding enzymatically active...
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7208303 |
Bacterial nitric oxide synthases and uses thereof
The present invention relates to isolated nucleic acid molecules encoding nitric oxide synthases. The isolated nucleic acid molecules and their encoded protein or polypeptides are useful in methods...
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7205140 |
Nucleotide sequence for creatinine deiminase and method of use
The present invention relates to the discovery of novel genes encoding a polypeptide having creatinine deiminase activity and methods of use. Also disclosed is a kit using the novel sequences for...
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7202077 |
Methods for enhancing the translation and expression of recombinant proteins
The increased use of nucleotide sequence data mining techniques has amplified the demand for efficient methods of producing recombinant proteins in prokaryotic cells. A strategy is provided for...
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7202059 |
Fusion proteins capable of being secreted into a fermentation medium
Fusion protein including a fusion part and a protein of interest, the combination of the two proteins leading to the fusion protein being secreted into a supernatant of a bacterial host with the...
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7192746 |
α-Isomaltosyltransferase, process for producing the same and use thereof
The object of the present invention is to provide an α-isomaltosyl-transferring enzyme which forms a cyclotetrasaccharide having the structure of...
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7183088 |
Thermophilic microorganism Bacillus coagulans strain SIM-T DSM 14043 for the production of L(+)-lactate from fermentable sugars and their mixtures
Thermophilic microorganism Bacillus coagulans strain SIM-7 DSM 14043 for the production of L(+)-lactate from fermentable sugars, including dextrines and starch. The temperature of cultivation is...
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7183093 |
Mannanases
The present invention relates to mannanases comprising e.g., a sequence of amino acids 32–330 of SEQ ID NO: 2 or their homologues may be derived from e.g., Bacillus sp. I633, or may be encoded...
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