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7470524 |
Method for producing L-amino acids using bacteria of the Enterobacteriaceae family
There is disclosed a method for producing an L-amino acid, for example L-threonine, L-lysine, L-histidine, L-phenylalanine, L-arginine, L-tryptophan or L-glutamic acid, using a bacterium of the...
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7470528 |
DNA encoding hydroxylase
The present invention relates to a protein derived from a microorganism belonging to the genus Bacillus , which has an activity of hydroxylating a compound represented by the formula (I-a):
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7470532 |
Mortierella alpina C16/18 fatty acid elongase
The present invention relates to a fungal C 16/18 fatty acid elongase that is able to catalyze the conversion of palmitate (16:0) to stearic acid (18:0). Specifically, the nucleotide sequence of a...
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7468262 |
Polynucleotides encoding useful polypeptides in corynebacterium glutamicum ssp. lactofermentum
The present invention provides novel polypeptides and polynucleotides useful as biotechnological tools, specifically identified in a coryneform bacterium Corynebacterium glutamicum ssp. ...
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7468278 |
Bacillus thuringiensis gene with coleopteran activity
The invention provides nucleic acids, and variants and fragments thereof, obtained from strains of Bacillus thuringiensis encoding polypeptides having pesticidal activity against insect pests,...
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7468185 |
Vaccine for periodontal disease
The present invention relates to novel bacterial isolates identified by their 16S rRNA DNA, that cause periodontal disease in companion animals, polynucleotide sequences contained therein,...
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7468269 |
Reagents for recombinogenic engineering and uses thereof
The present invention features homologous recombination methods and systems. The methods and systems promote highly efficient homologous recombination in cells (e.g., in prokaryotic cells). The...
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7468188 |
Multi-step therapy for injured muscles
Methods for treating an injured muscle by local administration of a neurotoxin, such as a botulinum toxin, to promote healing and/or to reduce the pain associated with an injured muscle.
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7468266 |
Isolated genomic polynucleotide fragments that encode human lipoprotein-associated phospholipase A2
The invention is directed to isolated genomic polynucleotide fragments that encode human lipoprotein-associated phospholipase A2, vectors and hosts containing the fragment and fragments hybridizing...
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7468268 |
Nucleic acid molecules encoding osteoclastogenesis inhibitory factor proteins
A protein which inhibits osteoclast differentiation and/or maturation and a method for producing the protein. The protein is produced by human embryonic lung fibroblasts and has a molecular weight...
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7465581 |
ANKTM1, a cold-activated TRP-like channel expressed in nociceptive neurons
The methods and compositions of the invention are based on a method for measuring nociceptive responses in vertebrates, including humans and other mammals utilizing a newly discovered...
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7465459 |
Piroplasmid vaccine
The invention relates to a Piroplasmid protein or an immunogenic fragment of the protein, and to a nucleic acid encoding the Piroplasmid protein or the immunogenic fragment. Furthermore, the...
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7465793 |
Synthetic Δ17 desaturase derived from Phytophthora ramourum and its use in making polyunsaturated fatty acids
The present invention relates to Δ17 desaturases, which have the ability to convert ω-6 fatty acids into their ω-3 counterparts (i.e., conversion of arachidonic acid [20:4, ARA] to...
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7465564 |
Production of γ-linolenic acid in oleaginous yeast
The present invention relates to methods for the production of γ-linolenic acid (GLA) in oleaginous yeast. Thus, Δ12 and Δ6 desaturases able to catalyze the conversion of oleic acid to GLA have...
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7465571 |
Endoglucanases
In one aspect, the invention provides a purified thermostable enzyme derived from the archael bacterium AEPII 1a. In one aspect, the enzyme has a molecular weight of about 60.9 kilodaltons and has...
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7465568 |
Essential fungal polynucleotides, polypeptides, and methods of use
The presnt invention provides essential fungal polynucleotides and their encoded polypeptides, homologues thereof and their uses. Additionally, the invention provides methods for the identification...
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7462477 |
Protein-deamidating enzyme, microorganism producing the same, gene encoding the same, production process therefor, and use thereof
A method for the production of an enzyme, which comprises culturing in a medium a strain that belongs to a bacterium classified into Cytophagales or Actinomycetes , or a new bacterium ...
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7462482 |
Human smooth muscle myosin heavy chain
The invention provides novel compositions, methods, and uses of hSMMyHC polypeptides and polynucleotides.
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7462693 |
Variants of the Gamma Chain of AMPX, DNA sequences encoding the same, and uses thereof
Variants of the gamma chain of vertebrate AMP-activated kinase (AMPK), as well as nucleic acid sequences encoding the variants and use thereof for the diagnosis or treatment of dysfunction of...
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7462466 |
Porcine CD59 nucleic acids and cells containing the same
A graftable animal cell or tissue of a donor species for use in medicine expresses, or is capable of being caused to express, increased amounts of endogenous complement regulatory molecules for...
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7462695 |
Insect chymotrypsin and inhibitors thereof
The present invention relates generally to a novel chymotrypsin that exhibits resistance to a plant serine proteinase inhibitor. More particularly, the present invention provides a chymotrypsin...
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7459292 |
Polynucleotides and expression system of a novel human G-protein coupled receptor
The present invention relates to novel identified polynucleotides, polypeptides encoded by them and to the use of such- polynucleotides and polypeptides, and to their production. More particularly,...
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7459161 |
Methods for eliciting an immune response using cytolysin and hemolysin fusion proteins
The disclosure below provides a protein export system for efficiently producing recombinant protein from a host cell. In a preferred embodiment, the protein export system utilizes protein export...
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7459165 |
Polypeptides of Pseudomonas aeruginosa
The present invention relates to polypeptides of Pseudomonas aeruginosa which may be used to prevent, diagnose and/or treat Pseudomonas aeruginosa infection.
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7459294 |
Method of producing a compound by fermentation
During the production of a product compound by fermentation, the concentration of a precursor compound is maintained within a pre-selected concentration range by having an adsorbent resin in...
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7459298 |
Purification, cloning and biochemical characterization of XendoU, endoribonucleasic activity involved in small nuclear RNA splicing-independent biosynthesis in Xenopus laevis
Cloning and characterization of the gene for Mn ++ dependent RNA-sc endoribonucleasic activity able to generate 2′-3′ cyclic phosphate and 5′OH ends.
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7459308 |
Nucleic acid molecule encoding a CLASP-2 transmembrane protein
The present invention relates to a cell surface molecules, designated cadherin-like asymmetry proteins (“CLASPs”). In particular, it relates to CLASP-2 polynucleotides, polypeptides, fusion...
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7459293 |
Cytokine zcytor17 ligand polynucleotides
The present invention relates to zcytor17lig polynucleotide, polypeptide and anti-zcytor17 antibody molecules. The zcytor17lig is a novel cytokine. The polypeptides may be used within methods for...
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7459300 |
Polypeptide Hormone Phosphatonin
The present invention relates to a novel human protein called phosphatonin, and isolated polynucleotides encoding this protein. Also provided are vectors, host cells, antibodies, and recombinant...
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7459434 |
Peptide interacting with anti-apoptotic proteins of the Bcl-2 family
The invention relates to the identification of a new peptide interacting with the anti-apoptotic proteins Bcl-2, Bcl-W and/or Bcl-XL, and also to screening methods allowing identification of...
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7459310 |
Cloning and expression of gonadotropin-releasing hormone (GnRH) receptors
An isolated and purified GnRH protein receptor protein including an amino acid sequence selected from the group and an isolated and purified DNA which comprises a nucleotide sequence coding for the...
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7455990 |
Method of extracting recombinant hexose oxidase
A method is described for releasing a soluble or membrane associated intracellular protein of interest (POI) comprising the steps of: providing a cell comprising a soluble or membrane associated...
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7456271 |
Glutamate 2,3-aminomutases and methods of use thereof
There are provided nucleic acids, including isolated DNA molecules, which encode glutamate 2,3-aminomutase enzymes, polypeptides produced from such nucleic acids and methods of making the nucleic...
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7456003 |
DNA sequences coding for enzymes capable of facilitating the synthesis of linear α-1,4 glucans in plants, fungi and microorganisms
DNA sequences coding for enzymes capable of facilitating the synthesis of linear □-1,4 glucans in plants, fungi and microorganisms. The invention relates to DNA sequences Coding for proteins...
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7456001 |
Lipoxygenase
The invention provides sequence information of a microbial protein having lipoxy-genase activity and a method of producing the protein by recombinant DNA technology. More specifically, the...
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7456269 |
Alzheimer's disease secretase, APP substrates thereof, and uses thereof
The present invention provides the enzyme and enzymatic procedures for cleaving the β secretase cleavage site of the APP protein and associated nucleic acids, peptides, vectors, cells and cell...
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7456272 |
Neurotoxins with enhanced target specificity
Modified neurotoxins that contain protease cleavage sites susceptible uniquely to proteases present in certain tissues are described. The toxins can be selectively activated by proteases in muscle...
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7456007 |
β-secretase enzyme compositions and methods
Disclosed is an active, isolated β-secretase enzyme in purified and recombinant form. This enzyme is implicated in the production of amyloid plaque components which accumulate in the brains of...
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7456011 |
Modified cyanovirin-n polypeptide
This disclosure relates to a modified version of cyanovirin-N protein and a transformed Lactobacillus bacterium that is capable of recombinantly expressing this modified protein. Further...
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7452983 |
Protein which binds to Akt2
A novel polypeptide, a polynucleotide, an expression vector, a cell transfected with the expression vector, a method for screening an insulin resistance improving agent and a carbohydrate...
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7452707 |
CBH1 homologs and variant CBH1 cellulases
Disclosed are a number of homologs and variants of Hypocrea jecorina Cel7A (formerly Trichoderma reesei cellobiohydrolase I or CBH1), nucleic acids encoding the same and methods for producing...
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7452688 |
Transformed cell with enhanced sensitivity to antifungal compound and use thereof
The present invention provides a transformed cell in which a polynucleotide having a nucleotide sequence encoding an amino acid sequence of an osmosensing histidine kinase having no transmembrane...
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7452694 |
Nucleic acids encoding T2R of taste receptors
The invention provides isolated nucleic acid and amino acid sequences of taste cell specific G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and...
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7452715 |
Production of the lipidated form of the peptidoglycan associated lipoproteins of gram-negative bacteria
The expression of the lipidated form of the peptidoglycan-associated protein (PAL) of gram-negative bacteria is achieved through the use of a plasmid containing a tightly regulated promoter. A...
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7452704 |
Dehydrogenase and a gene encoding the same
The object of the present invention is to provide a novel dehydrogenase having a property which is different from that of known dehydrogenases. The present invention provides a dehydrogenase having...
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7452705 |
N4 virion single-stranded DNA dependent RNA polymerase
A histidine-tagged, deletion mutant of bacteriophage N4-coded, virion RNA polymerase (mini-vRNAP) which is active has been developed. The his-tagged mini-vRNAP has been cloned under the control of...
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7452701 |
Methods for the preparation of β-amino acids
Purified β-amino acids are of considerable interest in the preparation of pharmacologically active compounds and industrial precursors. Although enantiomerically pure β-amino acids can be...
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7452706 |
Recombinant bacterial phytases and uses thereof
A purified recombinant phytase enzyme derived from Escherichia coli B. The enzyme has a molecular weight of about 47.1 kilodaltons and has phytase activity. The enzyme can be produced from native...
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7449316 |
UDP-galactose: β-D-galactose-R 4-α-D-galactosyltransferase, α4Gal-T1
A novel gene defining a novel enzyme UDP-galactose: β-D-galactose-R 4-α-D-galactosyltransferase, termed α4Gal-T1, with unique enzymatic properties is disclosed. The invention provides isolated...
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7449318 |
Bacillus mHKcel cellulase
The present invention provides a novel cellulase nucleic acid sequence, designated mHKcel, and the corresponding mHKcel amino acid sequence. The invention also provides expression vectors and host...
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