Sign up


Match Document Document Title
8697416 Recombinant polynucleotide, host cells containing the same and a process for producing a protein having aldolase activity  
4-(Indol-3-ylmethyl)-4-hydroxy-2-oxoglutarate, which is useful as an intermediate in the synthesis of monatin, may be synthesized from indole pyruvic acid and pyruvic acid (and/or oxaloacetic acid)...
8697409 Ketoreductase mutant  
Disclosed are a ketoreductase mutant which can be used for an efficient production of daunorubicin derivatives, a DNA encoding the mutant, a transformant prepared by introducing the DNA thereinto...
8697850 Process for preparing L-amino acids  
A process for preparing L-amino acids employing coryneform bacteria in which the AmtR regulator has been attenuated is provided. Recombinant bacteria, polynucleotides and vectors corresponding to...
8697398 Compositions and methods for bacterial production of chondroitin  
The invention relates to the field of recombinant DNA technology for the production of chondroitin, including the production of chondroitin sulfate via a combination of recombinant bacterial...
8697412 Polypeptides having glucoamylase activity and polynucleotides encoding same  
The present invention relates to isolated polypeptides having glucoamylase activity, catalytic domains, carbohydrate binding domains and polynucleotides encoding the polypeptides, catalytic domains...
8697392 Processes of producing fermentation products  
The invention relates to a process of fermenting plant material in a fermentation medium into a fermentation product using a fermenting organism, wherein one or more carbonic anhydrases are present...
8691553 Methods and organisms for utilizing synthesis gas or other gaseous carbon sources and methanol  
The invention provides a non-naturally occurring microbial organism having an acetyl-CoA pathway and the capability of utilizing syngas or syngas and methanol. In one embodiment, the invention...
8691539 Materials and methods for efficient succinate and malate production  
Genetically engineered microorganisms have been constructed to produce succinate and malate in mineral salt media in pH-controlled batch fermentations without the addition of plasmids or foreign...
8691525 Methods of combined bioprocessing and related microorganisms, thermophilic and/or acidophilic enzymes, and nucleic acids encoding said enzymes  
A genetically modified organism comprising: at least one nucleic acid sequence and/or at least one recombinant nucleic acid isolated from Alicyclobacillus acidocaldarius and encoding a polypeptide...
8691537 Method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family with attenuated expression of the rcsA gene  
The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus Escherichia or Pantoea, which...
8691547 Coenzyme-linked glucose dehydrogenase and polynucleotide encoding the same  
The present invention provides members that produce on a large scale a coenzyme-linked glucose dehydrogenase which has excellent substrate-recognizing ability toward glucose while providing low...
8691960 Oxidoreductases for enantioselective reactions  
Described herein are compositions and methods for generating oxidoreductases for enantioselective reactions. Described herein are compositions and methods for generating neomorphic...
8691541 Biological production of pentose sugars using recombinant cells  
The invention provides, inter alia, compositions and methods for the biological production of pentose sugars, such as 2-methylerythritol (2-ME), 1-deoxyxylulose (1-DX), and...
8691540 Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans  
From a bacterial strain isolated from an environmental sample, after enrichment in medium containing 1-butanol as the carbon source, a new enzyme with butanol dehydrogenase activity was identified....
8692070 Plants with improved nitrogen utilization and stress tolerance  
The present invention relates to transgenic plants that have increased nitrogen use efficiency, stress tolerance, and/or alleviating a limitation such that yield is increased, or a combination of...
8685413 Heterologous protection against Pasteurella multocida provided by P. multocida fur cells and the outer-membrane protein extracts thereof  
The invention relates to Pasteurella multocida mutants capable of providing heterologous protection against infection caused by virulent P. multocida . Said mutants are defective in fur ompH and...
8685705 Desmosterol-producing yeast strains and uses thereof  
The invention concerns the production of cholesterol of the Fungi kingdom. More particularly, the invention concerns genetically modified Fungus independently producing cholesterol from a simple...
8685669 Nucleic acid molecules encoding humanized antibody molecules specific for IL-31  
The invention provides humanized mouse anti-human IL-31 antibodies and antibody fragments that are capable of binding IL-31 and thereby neutralizing, inhibiting, limiting, or reducing the...
8685681 Diacylglycerol acyltransferases for alteration of polyunsaturated fatty acids and oil content in oleaginous organisms  
Acyltransferases are provided, suitable for use in the manufacture of microbial oils enriched in omega fatty acids in oleaginous yeast (e.g., Yarrowia lipolytica). Specifically, genes encoding...
8685701 Recombinant Ralstonia eutropha capable of producing polylactic acid or polylatic acid compolymer, and method for producing polylactic acid or polylatic acid copolymer using same  
Provided are a recombinant Ralstonia eutropha capable of producing polylactate or a hydroxyalkanoate-lactate copolymer, and a method of preparing polylactate or a hydroxyalkanoate-lactate copolymer...
8685688 Isolation of a protein responsible for uranium (VI) reduction  
The present invention relates to the isolation and characterization of a protein responsible for the reduction of uranium (VI) to uranium (IV). The present invention extends to the use of the...
8685683 Method for production of vitamin C and or 2-Keto-L gulonic acid  
The present invention relates to newly identified genes that encode proteins that are involved in the synthesis of L-ascorbic acid (hereinafter also referred to as Vitamin C) and/or...
8685735 Genes for modulating coffee maturation and methods for their use  
Disclosed are isolated nucleic acids for modulating coffee maturation. Also disclosed are promoters derived from such genes. Methods for using the nucleic acids for improving quality attributes of...
8685700 Method for enhancing production polyhydroxyalkanoic acid from microorganism strains  
Provided is a method for enhancing the production of polyhydroxyalkanoic acid (PHA) from microorganism strains by disrupting a gene associated with the production of an exobiopolymer (EBP) in the...
8685702 Compositions and methods for improved isoprene production using two types of ISPG enzymes  
The invention provides for compositions and methods for producing isoprene by using recombinantly engineered cells that utilize a system of dual IspG enzymes in addition to isoprene synthase.
8685673 Method for producing indole derivative  
The present invention provides a method for in vitro producing an indole derivative in a one-pot reaction. The method for producing a rhamnosylated indolocarbazole compound includes the steps of...
8685691 Method for producing aminopeptidase  
Disclosed is an efficient method for production of aminopeptidase. The method comprises either transforming host bacteria with an aminopeptidase gene and with a neutral protease gene, or...
8679818 BGL7 beta-glucosidase and nucleic acids encoding the same  
The present invention provides a novel β-glucosidase nucleic acid sequence, designated bgl7, and the corresponding BGL7 amino acid sequence. The invention also provides expression vectors and host ...
8679815 Expression of granular starch hydrolyzing enzyme in Trichoderma  
The present invention relates to filamentous fungal host cells and particularly Trichoderma host cells useful for the production of heterologous granular starch hydrolyzing enzymes having...
8679783 Recombinant factor X with no glycosylation and method for preparing the same  
A Factor X (hereinafter referred to as “FX”) with a high activity is provided. The present invention relates to a method for efficiently preparing a recombinant, two-chain FX which comprises int...
8679749 Red fluorescent proteins with enhanced bacterial expression, increased brightness and reduced aggregation  
Polynucleotides encoding variant polypeptides of DsRed are provided herein. The DsRed variants have increased bacterial expression, reduced aggregation, increased solubility, shifted emission...
8679800 Method for producing lactic acid from plant-derived raw material, and lactic-acid-producing bacterium  
The present invention provides: a lactic acid-producing Escherichia coli comprising at least one gene of a sucrose non-PTS gene group, including at least a sucrose hydrolase gene, provided that a...
8679813 Polypeptides having lipase activity and polynucleotides encoding same  
The present invention relates to polypeptide having lipase activity and which further has a RP of at least 0.8 and a BR of at least 1.1 at the test conditions given in the specification.
8679814 Protein and DNA sequence encoding a cold adapted xylanase  
A method of preparing a cold adapted xylanase by use of recombinant DNA techniques. A nucleic acid and corresponding amino acid sequences of a cold adapted xylanase, isolated from antarctic marine...
8679774 Lipolytic enzyme variants  
The substrate specificity of a lipolytic enzyme can be modified by making alterations to the amino acid sequence in a defined region of the lipolytic enzyme, so as to increase the level of a...
8679802 Methyl butenol synthase  
The present invention provides novels genes encoding methyl butenol (MBO) synthase, methy butenol synthases and their use in methyl butenol production.
8680248 Host cells comprising alpha 1,2 mannosidase and culture methods thereof  
Improved host cells and culture methods involving overexpression of MAN1C1 activity to improve protein production are provided.
8679799 Production of acid and solvent in microorganisms  
The invention relates to a method and means for the bioengineered fermentative production of solvents, in particular of butanol, acetone and ethanol, and of short-chained carboxylic acids such as...
8679822 Xylose utilization in recombinant zymomonas  
Xylose-utilizing Zymomonas strains studied were found to accumulate ribulose when grown in xylose-containing media. Engineering these strains to increase ribose-5-phosphate isomerase activity led...
8679493 Immunoglobulin Fc polypeptides  
Methods and compositions involving polypeptides having an aglycosylated antibody Fc domain. In certain embodiments, polypeptides have an aglycosylated Fc domain that contains one or more...
8679821 Bacteriophage derived methods to control lactic acid bacterial growth  
Compositions and methods for protection against bacterial contamination are disclosed Antibacterial proteins and methods of use thereof are also disclosed.
8673590 Method for producing dipeptide  
The invention provides a microorganism having an ability to produce a protein having a dipeptide synthesizing activity and in which an activity of the protein to transport a dipeptide in a...
8673591 Genetic incorporation of 3-aminotyrosine into reductases  
This invention provides reductase proteins that comprise NH2Y unnatural amino acid residues, systems of orthogonal elements for incorporating NH2Y into reductases and methods of using NH2Y amino...
8673601 Methods and organisms for growth-coupled production of 3-hydroxypropionic acid  
The invention provides a non-naturally occurring microorganism having one or more gene disruptions, the one or more gene disruptions occurring in genes encoding an enzyme obligatory coupling...
8674083 Polypeptide variants with altered effector function  
The present invention concerns polypeptides comprising a variant Fc region. More particularly, the present invention concerns Fc region-containing polypeptides that have altered effector function...
8673602 Recombinant bacteria having improved sucrose utilization  
Recombinant bacteria having an improved ability to utilize sucrose are provided. These recombinant bacteria have nucleotide sequences encoding sucrose utilization polypeptides integrated into their...
8673578 Methods of identifying antagonists of the hTAS2R46 bitter taste receptor  
The present invention relates to antagonists and agonists of the human bitter-taste receptors hTAS2R40, hTAS2R43, hTAS2R44, hTAS2R46, and hTAS2R47. The invention also relates to methods for...
8673614 Anaerobic microbial composition and methods of using same  
A microbial composition for concurrent dechlorination of a mixture of chlorinated ethanes and chlorinated ethenes includes a isolated consortium of bioremediative microorganisms comprising strains...
8673607 Ketoreductase polypeptides for the production of a 3-aryl-3-hydroxypropanamine from a 3-aryl-3-ketopropanamine  
The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides...
8669092 Urocortin-III and uses thereof  
A search of the public human genome database identified a human EST, GenBank accession number AW293249, which has high homology to known pufferfish urocortin sequences. The full length sequence was...