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8404475 Isolation of novel bacteria contributing to soilborne disease suppression  
Embodiments relate to plant disease suppressive microorganisms and compositions including the same, methods for isolating disease suppressive microorganisms, and methods for controlling plant...
8404823 Cytokine production regulator gene and use thereof  
The invention provides a gene encoding a protein selected from among the following proteins (a) to (c): (a) a protein having any of the amino acid sequences of SEQ ID NOs: 2, 4, 6, 8, 10, 12, 14,...
8404466 Metabolically enhanced photoautotrophic ethanol producing host cells, method for producing the host cells, constructs for the transformation of the host cells, and method of producing ethanol using the host cells  
One embodiment of the invention provides a metabolically enhanced photoautotrophic, ethanol producing host cell comprising: at least two first metabolic enhancements reducing the enzymatic activity...
8404472 System for producing aromatic molecules by bioconversion  
Yeast comprising at least one gene encoding vanillyl alcohol oxidase, the sequence of which is the sequence SEQ ID No. 1 or any sequence at least 70%, preferably 80%, very preferably 90% homologous...
8399240 Method and gene for providing or enhancing nonspecific adhesive property and/or autoagglutinating property for microorganisms  
A method for providing or enhancing a nonspecific adhesive property, an autoagglutinating property, or both properties in a microorganism is provided. The method comprises introducing a nucleic...
8399647 Alpha5-beta1 antibodies and their uses  
The present disclosure provides isolated monoclonal antibodies, particularly human monoclonal antibodies, or antigen binding portions thereof, that specifically bind to integrin α5β1 with high a...
8399631 Compositions and methods for purifying calreticulin  
The present invention relates to compositions, methods for expressing, and related methods for purifying calreticulin that is free of an affinity label or tag (i.e., non-tagged calreticulin). The...
8399232 Enzyme associated with equol synthesis  
An object of the present invention is to provide enzymes associated with equol synthesis, genes coding such enzymes, and a process for producing equol and its intermediates using the enzymes and...
8398989 Human cystathionine β-synthase variants and methods of production thereof  
Human cystathionine β-synthase variants are disclosed, as well as a method to produce recombinant human cystathionine β-synthase and variants thereof. More particularly, the role of both the N...
8394607 Anti-CD22 antibodies and immunoconjugates and methods of use  
Anti-CD22 antibodies and immunoconjugates thereof are provided. Methods of using anti-CD22 antibodies and immunoconjugates thereof are provided.
8394618 Lipase-containing polymeric coatings for the facilitated removal of fingerprints  
A substrate or coating is provided that includes a lipase with enzymatic activity toward a component of a fingerprint. Also provided is a process for facilitating the removal of fingerprints is...
8394619 Beta-glucosidase and uses thereof  
A novel beta-glucosidase and nucleic acids encoding the beta-glucosidase. Also disclosed are cells, compositions, and methods relating to using the beta-glucosidase to convert ligocellulosic...
8394373 ADAMTS13 genes and proteins and variants, and therapeutic compositions and methods of utilizing the same  
The present invention relates to a disintegrin and metalloproteinase containing thrombospondin 1-like domains (ADAMTS) and in particular to a novel ADAMTS13 protease and to nucleic acids encoding...
8394615 Glucose dehydrogenase  
The invention provides a glucose dehydrogenase that is an extremely stable enzyme having a thermostability of 80° C. or more, and that does not substantially act upon saccharides other than ...
8394928 Humanized anti-CDCP1 antibodies  
The present invention relates to humanized antibodies against human CDCP1 (anti-CDCP1 antibody), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
8389264 Recombinant microorganism that expresses a secY gene with deletion of sporulation-associated genes and method of producing thereof  
A recombinant microorganism having improved productivity for a protein or a polypeptide, and a method for producing a protein or a polypeptide using the recombinant microorganism, are provided. A...
8389214 Glucose transport mutants for production of biomaterial  
A method is disclosed for restoring a Glu+ phenotype to a PTS−/Glu− bacterial cell which was originally capable of utilizing a phosphotransferase transport system (PTS) for carbohydrate tra...
8389685 Vector encoding a plasmid replication protein and use thereof  
To provide a plasmid vector having high productivity which can be used for large scale production of an industrially valuable and useful protein, and a transformant using the plasmid vector. A...
8389241 Enzyme that catalyzes a peptide-forming reaction from a carboxy component and an amine component, microbe producing the same, and a method of producing a dipeptide using the enzyme or microbe  
DNA and recombinant DNA that encode a peptide-forming enzyme, a method for producing a peptide-forming enzyme, and a method for producing a dipeptide are disclosed. A method for producing a...
8389265 Gene associated with foam formation of acetic acid bacterium, acetic acid bacterium bred by modifying the gene and method for producing vinegar using the acetic acid bacterium  
The present invention provides a method for reducing or deleting the function of a protein encoded by the glyT gene in an acetic acid-producing bacterium. This method significantly suppresses foam...
8389250 Methods for producing methionine by culturing a microorganism modified to enhance production of cysteine  
A method of producing methionine, derivatives or precursors thereof comprising culturing a microorganism modified to enhance production of cysteine in a culture medium comprising a source of carbon...
8389262 Subtilase variants having altered immunogenicity  
The present invention relates to subtilase subtilases with an altered immunogenicity, particularly subtilases with a reduced allergenicity. Furthermore, the invention relates to expression of said...
8383387 Subtilases  
The present invention relates to methods for producing variants of a parent TY145 subtilase and of a parent BPN′ subtilase and to TY145 and BPN′ variants having altered properties as compared to ...
8383377 Bacterium capable of fermenting glucose, mannose and xylose simultaneously, and method for production of bioethanol using the bacterium  
The object is to develop a bacterium capable of fermenting glucose, mannose and xylose simultaneously, which can ferment a saccharified solution of a cellulose-type or lignocellulose-type biomass...
8383372 L-cysteine producing bacterium and a method for producing L-cysteine  
The present invention describes a bacterium belonging to the family Enterobacteriaceae which has L-cysteine-producing ability and has been modified to decrease the activity of a protein encoded by...
8383802 Nucleic acids encoding antibodies that bind factor D  
The invention relates to factor D inhibitors, which bind to factor D and block the functional activity of factor D in complement activation. The inhibitors include antibody molecules, as well as...
8383389 Hydroxynitrile lyase  
An improved hydroxynitrile lyase characterized by having a mutation of substitution of at least one amino acid residue in the amino acid sequence of a wild-type hydroxynitrile lyase with another...
8383383 Polypeptides having lipase activity and polynucleotides encoding same  
The present invention relates to isolated polypeptides having lipase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors,...
8383568 Polyol oxidases  
The present invention provides compositions and methods for producing a polyol oxidase in micoroorganisms, and the use of polyol oxidases in cleaning compositions. The invention includes cleaning...
8383370 Modified RNA ligase for efficient 3′ modification of RNA  
The invention provides a novel truncated mutated T4 RNA ligase 2. In addition, methods are provided for ligating pre-adenlylated donor molecules to the 3′ hydroxyl group of RNA in the absence of A...
8383367 IL-21 variant nucleic acids  
IL-21 variants nucleic acid sequences are provided that encode a peptide having deletions and zero to ten conservative amino acid substitutions in the region of amino acid residues 65-96 of SEQ ID....
8383774 Collectin fusion proteins comprising TNF or trail  
The present invention refers to a fusion protein comprising a TNF-superfamily (TNFSF) cytokine or a receptor binding domain thereof fused to a collectin trimerization domain, to a nucleic acid...
8383374 Materials and methods for the efficient production of acetate and other products  
The subject invention provides materials and methods wherein unique and advantageous combinations of gene mutations are used to direct carbon flow from sugars to a single product. The techniques of...
8383398 Expression vector  
A conventional shuttle vector constructed by fusing an E. coli-derived plasmid and a transformant-derived plasmid functions in both E. coli and the transformant bacterium, and there exists no...
8383388 Modified coagulation factor IX polypeptides and use thereof for treatment  
Provided are modified factor IX (FIX) polypeptides and methods of generating modified FIX polypeptides. Also provided are pharmaceutical compositions, including compositions formulation for oral...
8383391 Mutant cell with deleted or disrupted genes encoding protease  
This disclosure relates to mutant cells with deleted or disrupted genes encoding protease(s).
8377677 Protease variants  
The invention relates to a novel 3D structure encoding a Nocardiopsis protease, as well as to variants of parent protease homologous to Nocardiopsis proteases, preferably of improved...
8377671 [NiFe]-hydrogenases having an improved resistance to dioxygen, process for obtaining them and their applications  
The invention relates to [NiFe]-hydrogenases having an improved resistance to dioxygen, said [NiFe]-hydrogenases may be obtained by:—providing an initial polynucleotide comprising a sequence e...
8378186 Expression of fatty acid desaturases in corn  
The invention relates generally to the expression of desaturase enzymes in transgenic corn plants and compositions derived therefrom. In particular, the invention relates to the production of oils...
8378173 Transcription factor gene OsNACx from rice and use thereof for improving plant tolerance to drought and salt  
The present invention relates to an isolated polynucleotide capable of giving a plant tolerance to drought and/or salt stress, which comprises a polynucleotide sequence as shown in SEQ ID NO:1, and...
8377680 Microorganisms and methods for the biosynthesis of adipate, hexamethylenediamine and 6-aminocaproic acid  
The invention provides a non-naturally occurring microbial organism having a 6-aminocaproic acid, caprolactam, hexametheylenediamine or levulinic acid pathway. The microbial organism contains at...
8377666 Microorganisms for the production of 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-coa, putrescine and related compounds, and methods related thereto  
The invention provides non-naturally occurring microbial organisms comprising a 1,4-butanediol (BDO), 4-hydroxybutyryl-CoA, 4-hydroxybutanal or putrescine pathway comprising at least one exogenous...
8377667 Microorganisms for the production of 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-CoA, putrescine and related compounds, and methods related thereto  
The invention provides non-naturally occurring microbial organisms comprising a 1,4-butanediol (BDO), 4-hydroxybutyryl-CoA, 4-hydroxybutanal or putrescine pathway comprising at least one exogenous...
8372392 Lactobacillus paracasei strain LT12 as immunity regulatory agent  
An isolated Lactobacillus paracasei strain LT12 and its genetically-engineered variant that possesses immune regulating activity and uses thereof for regulating immune responses and treating allergy.
8372624 Genetically engineered biological indicator  
The disclosed technology relates to a genetically engineered biological indicator, comprising: at least one test organism and at least one reporter gene suitable for producing an indicator enzyme,...
8372623 Compositions and methods for altering alpha- and beta-tocotrienol content using multiple transgenes  
Preparation and use of isolated nucleic acids useful in altering the oil phenotype of plants are described. Isolated nucleic acids and their encoded polypeptides are described that alter the...
8372601 Compositions and methods for the synthesis of APPA-containing peptides  
The disclosure of the present application provides polypeptide sequences and nucleotide sequences coding for the polypeptide sequences of proteins used in the production of APPA-containing...
8373024 Method for producing unsaturated ω-3-fatty acids in transgenic organisms  
The present invention relates to nucleic acid sequences coding for polypeptides with ω-3-desaturase activity. The invention furthermore relates to nucleic acid constructs, vectors and organisms ...
8373023 Biochemical route to astaxanthin  
Two sequences of a nucleic acid isolated from a cDNA library of the flowering plant Adonis aestivalis is disclosed (SEQ ID NO: 5). The first DNA sequence, referred to as AdKC28, encodes for a...
8372403 Humanized anti-factor D antibodies and uses thereof  
The invention relates to humanized anti-human Factor D monoclonal antibodies, their nucleic acid and amino acid sequences, the cells and vectors that harbor these antibodies and their use in the...