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5334508 |
Process and agent for the colorimetric determination of an analyte by means of enzymatic oxidation
The present invention provides a process for the colorimetric determination of an analyte by means of enzymatic oxidation of the analyte in the presence of an electron acceptor and determination of...
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5332662 |
Methods for determining peroxidatively active substances
Methods and compositions are disclosed for determining a peroxidatively active substance (PAS). The methods comprise the step of detecting a fluorescent signal produced upon cleavage of a compound...
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5326697 |
Composition and method of assaying for D-β-hydroxybutyrate
A composition, test device and method of determining the presence or concentration of ketone bodies, and specifically D-β-hydroxybutyrate, in a test sample are disclosed. The test device includes...
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5324828 |
1-amino-1-deoxyoligosaccharides and derivatives thereof
A derivatized 1-amino-1-deoxyoligosaccharide prepared by reacting, at a pH of at least 6.5, a glycopeptide or glycoprotein containing one or more Asn-linked oligosaccharides with a...
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5314804 |
Test for Helicobacter pylori
A rapid method and easy to use unitized test device is disclosed for determining the presence of Helicobacter pylori in a biological tissue specimen by detecting the presence of urease in the...
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5312762 |
Method of measuring an analyte by measuring electrical resistance of a polymer film reacting with the analyte
The change in electrical resistance of an electroactive polymer such as polypyrrole, polyaniline or polythiophene when it reacts with an analyte is used to measure the analyte. The open circuit...
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5306624 |
Process of quantifying cell number
The present invention provides a process of quantifying the number of viable cells in an aqueous suspension of cells using an energy-emitting non-hazardous probe and a probe-trigger. The process...
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5306623 |
Visual blood glucose concentration test strip
A separation matrix impregnated with a separating agent separates red blood cells or hemoglobin from whole blood. Upon separation, an impregnated test reagent reacts with the separated...
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5304469 |
Propylene glycol as an activator for phosphoenolpyruvate carboxylase
The present invention provides an improved method and reagent for measuring the total carbon dioxide content in a sample of body fluid. The improvement comprises adding a sufficient amount of...
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5302513 |
Method for determination of components
The present invention relates to a method for quantitative determination of NAD(P)H derived from a specific component, which comprises converting NAD(P)H present in a sample or formed from...
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5298410 |
Lyophilized formulation of polyethylene oxide modified proteins with increased shelf-life
Disclosed are lyophilized biologically active proteinaceous compositions containing low diol polyalkylene oxide, such as polyethylene glycol, covalently attached to a biologically active...
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5294540 |
Ethanol analytical element
A multilayer analytical element for quantitatively assaying ethanol comprising a tetrazolium salt, alcohol dehydrogenase, NAD + , and an electron transfer agent characterized in that the layer...
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5294539 |
Nitrate reductase from yeasts, the preparation and use thereof
The invention relates to NAD(P)H-dependent nitrate reductase from yeasts, to a process for the preparation thereof and to the use thereof in a reagent for determining nitrate. The nitrate reductase...
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5290682 |
Enzyme controlled processes and products
Compounds which are useful as substrates for enzymes are disclosed. An enzyme-controlled process is provided for generating a colored species from an initially substantially colorless material as a...
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5288606 |
Reagent for specific determination of fructosamine
The present invention provides a process for the specific determination of the serum fructosamine content in blood or samples derived from blood by reaction with an appropriate color reagent and...
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5288613 |
Enzyme-based biosensor system for monitoring the freshness of fish
The present invention relates to a method for determining the degree of freshness of raw, frozen and processed edible fish by monitoring the degradation of adenine triphosphate to inosine...
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5286627 |
Method of high-sensitive analysis of bile acid and reagent composition for the analysis
A method for a high-sensitivity quantitative analysis of bile acid in a bile acid-containing sample utilizes a reagent comprising: (1) a steroid dehydrogenase which is capable of effecting a...
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5284948 |
Drug hapten analogues for immunoassays
The invention is directed to new drug hapten analogues comprising: (A) an active ester group; (B) a drug hapten nucleus selected from a hydantoin nucleus or a barbiturate nucleus and (C) a...
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5284754 |
Process for the continuous conversion of cephalosporin derivatives into glutaryl-7-aminocephalosporanic acid derivatives
A process for the continuous conversion of cephalosporin derivatives into glutaryl-7-aminocephalosporanic acid derivatives A process for the continuous conversion of cephalosporin derivatives into...
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5279945 |
Method for the enzymatic determination of aspartame
The aspartame content in aqueous solutions is determined by enzymatic cleavage of aspartame to aspartic acid and phenylalanine methyl ester by means of a peptidase, followed by a detection reaction...
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5279944 |
Method and reagent composition for the determination of alanine aminotrasferase and HBsAg antigen in the same biological specimen
The enzyme alanine aminotransferase (ALT) is colorimetrically determined as the hydrogen peroxide obtained in the pyruvate hydrolysis reaction catalysed by the enzyme pyruvate oxidase which...
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5272060 |
Method for determination of glucose concentration in whole blood
There is provided a method for the determination of a glucose concentration in a whole blood utilizing a biosensor. A correction of the measured glucose concentration for dilution error introduced...
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5270173 |
Method of monitoring cell culture
A method of monitoring cell culture which comprises digitizing an image of cultured cells inputted to an image processing equipment through a TV camera connected with an observing means and...
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5266462 |
Measurement of platelet activities
Methods are provided for measuring the procoagulant activity of platelets in blood by means of a chromogenic assay which is specific for procoagulant phospholipids. These methods include the...
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5264348 |
Ascorbate interference-resistant composition, device and method of assaying for predetermined analyte
A new and improved test device and method of determining the presence or concentration of a predetermined analyte, such as glucose, cholesterol or occult blood, in a test sample are disclosed. The...
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5264346 |
Colorimetric method for beta-lactamase assay and its applications
A novel colorimetric method for beta-lactamase assay and its applications are disclosed. The novel assay method for beta-lactamase is based on the discovery described in this invention. The...
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5262304 |
Method for optical measurement of bilirubin and reagent therefor
A method for optical measurement of bilirubin which comprises reacting a bilirubin-containing sample with a zinc compound, a coloring agent and bilirubin oxidase in a buffer, wherein a stable green...
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5262305 |
Interferant eliminating biosensors
A biosensor including an interferant-eliminating catalyst and method for analyzing an analyte in a biological sample is disclosed.
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5262299 |
Enzyme-amplified lanthanide chelate luminescence
A method and compounds useful for this method are described for enzyme-amplified signal detection in analytical assays requiring extremely high detection sensitivity which uses a substrate capable...
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5260196 |
Method for the diagnosis of Tourette syndrome and associated disorders
Differences in the rate of kynurenine formation in the lysates of red blood cells of a patient suspected of having Tourette syndrome, Tourette syndrome associated disorders or Tourette spectrum...
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5260195 |
Nonaqueous polymeric reagent compositions and applications thereof
Non-aqueous, polymeric reagent film compositions for use with analytical test devices of the dry chemistry type are described. The film compositions are prepared from an organic solution of a...
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5260197 |
L-fucose dehydrogenase, a process for production thereof, quantitative assay for L-fucose using said enzyme and a kit for quantitative assay
L-Fucose dehydrogenase having the following Physicochemical properties (1) and (2): (1) Action and substrate specificity It withdraws hydrogen from L-fucose and converts into L-fuconolactone...
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5254461 |
Method of and apparatus for determining microorganism populations electrochemically
A method of determining populations of live, whole bacteria electrochemically. The bacteria are filtered, and the filtrate is employed in association with an electrochemical measuring unit to...
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5250439 |
Use of conductive sensors in diagnostic assays
A conductive sensor and its use in a diagnostic assay are disclosed. The miniaturized conductive sensor, utilizing a conducting polymer, is used in a diagnostic device to determine the presence or...
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5250416 |
Method for highly sensitive determination of NADH using kinase
The present invention relates to a method for determining a slight amount of NADH or XTP which is present in a solution, with high sensitivity by the use of an NADH kinase specific for NADH by...
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5250420 |
Method and reagent for determination of dehydrogenase or its substrate
A method for determining dehydrogenase or its substrate in dehydrogenase reaction, which comprises subjecting a dehydrogenase and its substrate to dehydrogenase reaction in the presence of an...
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5250419 |
Method for the direct measurement of at least one chemical parameter of skin using a biosensor
This biosensor comprises a membrane (8), in which an enzyme catalyzing the transformation of a substrate used in the cutaneous metabolism is immobilized, means for detecting and measuring a...
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5240843 |
Enzyme stabilisation
A method of stabilising enzymes or other proteins against denaturation or drying comprises mixing the protein with a cyclic polyol and a cationic polyelectrolyte.
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5238817 |
Chromogenic substrates for improving detection in a peroxidase-based assay
A substrate for detecting peroxidase activity in a peroxidase-based assay which includes a substantially aqueous solution of at least a 1-naphthol derivative and tetramethylbenzidine is described.
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5238818 |
Oxidizable color producing reagent
This amount of an oxidative substance or a peroxidase-like substance can be determined by using a combined color former comprising 4-aminoantipyrine or a derivative thereof, etc., as a main color...
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5229296 |
Use of polymer-copper complex to control interference of biological substances in colorimetric test systems
Disclosed is a method for separating biological substances, particularly hemoglobin or bilirubin, from blood plasma or serum which involves contacting the plasma or serum with a water insoluble...
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5221615 |
Liquid stable triglyceride reagent system
A stable triglyceride assay solution for use with a chromogen system is comprised of a solution buffered with a Zwitterionic buffering agent and/or TRIS and stabilized with sortibol, gelatin, and...
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5217874 |
Fecal occult blood test product with positive and negative controls
A test sheet for the determination of the presence of a substance having peroxidase-like activity in a throw-in-the-bowl fecal occult blood test, includes a specimen test area and a positive...
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5215885 |
Stable two-part chromogen substrate
A two part peroxide/chromogen reagent for use in peroxidase labeled binding assays which is stable for at least about 24 hours is disclosed. The reagent is provided as two components, the first...
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5215886 |
HDL determination in whole blood
High density lipoprotein-cholesterol determination is made employing a device which allows for removal of red blood cells, measurement of sample volume, removal of LDL and VLDL, and quantitation of...
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5215887 |
Glucose sensor measurement
Disclosed is a method of measuring glucose concentration of a sample solution using a glucose sensor having an ion-sensitive field-effect transistor which can detect pH change in the sample...
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5213966 |
Quantitative determination of glucose utilizing enzyme cascade system
A procedure is disclosed for the determination of glucose in a biological liquid, as well as a reagent mixture for use in conjunction with the procedure. The biological liquids concerned are...
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5206149 |
Method of high sensitivity luminescence analysis
This invention relates to a method of high sensitivity luminescence analysis using, as an enhancer, 2-hydroxy-9-fluorenone, the compound expressed by the following formula ##STR1## or an oxazole...
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5206147 |
Colorimetric assay by enzymatic oxidation in the presence of an aromatic nitroso or oxime compound
The present invention provides a process for the colorimetric determination of an analyte by means of enzymatic oxidation of the analyte in the presence of an electron acceptor and determination of...
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5206145 |
Method of measuring the concentration of a substance in a sample solution
An apparatus is provided for measuring the concentration of a substance in a sample solution. The apparatus comprises first electrode means, second electrode means and an enzyme channel between the...
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