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7611885 |
Pharmaceutically compatible method for purifying intact bacterial minicells
The present invention provides a method for purifying bacterial minicells that involves subjecting a sample containing minicells to density gradient centrifugation in a biologically compatible...
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7604978 |
Inhibition of biofilm formation
The present invention relates to compositions and methods for reducing or inhibiting biofilm comprising modulating expression of a cysB gene in a cell. The invention also provides methods for...
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7566528 |
Method for the identification and/or validation of receptor tyrosine kinase inhibitors
An in vivo method for the identification and/or validation of receptor tyrosine kinase inhibitors is described. Said method is characterized by the following steps: providing host cells comprising...
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7560264 |
High density growth of T7 expression strains with auto-induction option
Disclosed is a method for promoting auto-induction of transcription of cloned DNA in cultures of bacterial cells grown batchwise, the transcription being under the control of a promoter whose...
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7556929 |
Compositions and methods for screening anti-cancer agents in yeast
Methods and kits for identifying novel anti-tumor agents are provided.
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7547536 |
Method for detecting bacterial spores
A method of detecting the presence and quantity of bacterial spores, which includes adding an electrophilic alcohol and an acid anhydride to a sample, admixing the sample with a solvent, and...
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7501278 |
Extracellular potential measuring device and method for fabricating the same
A device for measuring an extracellular potential of a test cell includes a substrate having a well formed in a first surface thereof and a first trap hole formed therein. The well has a bottom....
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7476529 |
Altering metabolism in biological processes
Compositions of peptides and surface-active agents are described, as are methods of making and using such compositions. The compositions are capable of affecting metabolic rates in biological...
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7452721 |
Practical serological assay for the clinical diagnosis of leishmaniasis
Methods for the diagnosis of visceral, cutaneous and canine leishmaniasis in a subject suspected of being infected with the parasitic protozoa Leishmania is disclosed. Disclosed are...
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7440160 |
Electro-optical light modulating element, electro-optical display and modulating medium
The invention relates to electrooptical light modulating elements, to electrooptical displays containing elements of this type, and to display systems, e.g. television screens and computer...
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7435578 |
Device and methods for monitoring the status of at least one cell
A device and methods for monitoring status of at least one cell, wherein the cell has a membrane forming a substantially enclosed structure and defining an intracellular space therein. In one...
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7396672 |
Method for the production of dinoflagellate cultures
A method for selectively enhancing the growth of the population of a dinoflagellate comprises incubating a medium containing at least one dinoflagellate cell in the presence of mimosine or a toxic...
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7319028 |
Process for producing sporangia of Bacillus popilliae, control agent, and controlling method
The present invention provides a process for efficiently producing sporangia of Bacillus popilliae containing spores and parasporal bodies having controlling effects on Scarabaeidae insects,...
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7279301 |
Methods of determining deficiencies in intracellular levels on cysteine and glutathione
The present invention provides a method for determining an antioxidant deficiency in a lymphocyte by determining the level of intracellular cysteine in the lymphocyte by measuring lymphocyte growth...
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7264951 |
Enhanced production of taxol and taxanes by cell cultures of Taxus species
This invention provides methods whereby taxol, baccatin III, and other taxol-like compounds, or taxanes, can be produced in very high yield from all known Taxus species, e.g., brevifolia,...
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7241589 |
Method for preparation of androst-4-ene-3,17-dione and androsta-1,4-diene-3,17-dione
The present invention relates to a method for preparation of androst-4-ene-3,17-dione (AD) and androsta-1,4-diene-3,17-dione (ADD). More particularly, the present invention relates to a method for...
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7166290 |
Methods for producing oocysts
The present invention provides improved methods and compositions for producing oocysts. The oocysts produced according to the invention find use in the manufacture of vaccines. In preferred...
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7063969 |
Yeast-based process for production of l-pac
The invention provides a method of synthesis of a substituted or unsubstituted carbinol compound, comprising the steps of subjecting the corresponding substituted or unsubstituted aromatic aldehyde...
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7018838 |
Substrates, devices, and methods for cellular assays
The present invention relates to the field of molecular diagnostics, and in particular to diagnostics based on a liquid crystal assay format. In particular, the present invention provided improved...
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7018813 |
Method for the production of bacterial toxins
Methods and compositions are provided for the enhanced production of bacterial toxins in large-scale cultures. Specifically, methods and compositions for reducing bacterial toxin expression...
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7011957 |
Isolation and cultivation of microorganisms from natural environments and drug discovery based thereon
The method of the invention is directed to the novel use of a diffusion chamber within which previously “uncultivatible” microorganisms can be isolated. Rather than attempting to replicate the...
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7001758 |
Microbial biodegradation of phosphonates
A biodegradation process for the organophosphonate product of Sarin (O-isopropyl methylphosphonofluoridate) hydrolysis, i.e., isopropylmethylphosphonate (IMPA). This process provides a feasible...
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6991931 |
Method for the use of polyhydroxyalkanoate levels to maintain bioreactor health
A method has been developed to maintain the health of an activated sludge environment in a wastewater process comprising monitoring the levels of polyhydroxyalkanoates (PHA) produced as an...
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6977166 |
Method of producing an oil including docosahexaenoic acid
C. cohnii is cultured in a suitable growth medium with acetic acid/acetate as the main carbon source. The acetate is provided, and replenished, by adding acetic acid to the growth medium in...
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6955911 |
Method of culturing microorganism
In cultivating a microorganism having nitrile hydratase production ability, by allowing at least one of a ketose, such as fructose, and a sugar alcohol, such as mannitol, to be present, growth...
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6946277 |
Method for enhancing cellobiase activity of termitomyces clypeatus using a glycosylation inhibitor
This invention provides a method for enhancing the cellobiase activity of the strain Termitimyces clypeatus using 2-deoxy-D-glucose as glycosylation inhibitor, said process comprises inoculating...
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6939705 |
Method of protecting L. johnsonii La1 against stress
A bacterial cell having protection against conditions which are lethal to an unprotected bacterial cell wherein, the protected cell is obtained by subjecting a bacterial cell to treatment with a...
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6919197 |
Materials and methods for the efficient production of Pasteuria
The subject invention provides novel and advantageous methods for growing bacteria. The methods of the subject invention are particularly advantageous for growing parasitic bacteria, in vitro,...
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6893857 |
Method for using hops acid for controlling microorganisms in a sugar-containing aqueous process medium
The invention relates to a method for controlling microorganisms in a sugar-containing aqueous process medium, especially in the sugar industry, using hop bitter acid as active substance. The hop...
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6872562 |
Herbicide resistant dinitrogen fixing bacteria and method of use
The present invention is directed to herbicide resistant N 2 fixing bacteria. The bacteria are useful for effecting N 2 fixation, nodulation, growth and yield of herbicide resistant or tolerant...
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6867023 |
Production method of polyhydroxyalkanoate from substituted fatty acid ester as raw material
Polyhydroxyalkanoates comprising a monomer unit having the following chemical formula (2):
(where the reference characters R represents an arbitrarily selected substituent and x represents an...
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6855536 |
Materials and methods for the enhancement of effective root nodulation in legumes
The subject invention relates to compounds and compositions which induce transcripts of the nolA gene in nitrogen-fixing bacteria, such as Bradyrhizobium japonicum . Novel bacterial strains which...
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6846667 |
Virulence genes and proteins, and their use
The present invention is based on the identification of a series of virulence genes in E. coli K1, the products of which may be implicated in the pathogenicity of the organisms. The...
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6843961 |
Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light
Methods and apparatuses are provided for inactivation of pathogens in fluids containing blood products. Preferred methods include the steps of adding an effective, nontoxic amount of a...
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6825002 |
Process for producing carotenoid pigments
The present invention provides a method for changing production ratios of carotenoid compounds in a process of microbiological production of a plurality of carotenoid compounds. By controlling the...
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6818211 |
Gram-positive fatty acid degrader
The invention discloses a Gram-positive microorganism, Bacillus megaterium that effectively and efficiently degrades fats, oils and grease. A composition comprising said microorganism and a...
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6812007 |
Process for the isolation and purification of mevinolin
In a process for preparing mevinolin by fermentation of a biomass in a fermentation liquor, which includes dissolving mevinolin from the biomass into the fermentation liquor, and separating the...
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6794175 |
Strain of Eubacterium that detoxyfies trichothenes
Microorganism of the genus Eubacterium, and its obtainment and use, which is suitable in pure culture, DSM 11798, and/or mixed culture with the strain Enterococcus casseliflavus , DSM 11799, or in...
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6767533 |
Use of a substance binding with the peripheral benzodiazepin receptor for treating skin stress
A composition containing a peripheral benzodiazepine receptor ligand for topical use in the treatment of cutaneous stress.
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6750012 |
Method of identifying a psychotropic agent using differential gene expression
Disclosed are methods of identifying psychotropic agents that do not induce motor side effects using differential gene expression. Also disclosed are novel nucleic acid sequences whose expression...
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6716617 |
Fermentation method with continuous mass cultivation of ciliates (protozoa) for producing biogenous valuable substances
In the fermentation process according to the invention with continuous mass cultivation of ciliates (protozoa), the ciliate cells are cultivated in a complex axenic medium—free from living feed...
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6682914 |
Bioactive tetracyclic diterpene compounds and methods of preparation and use thereof
Newly-isolated and purified metabolites which are effective in regulating the development of at least one filamentous fungal microorganism species are disclosed. These compounds, which are referred...
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6677149 |
Method for stabilizing nitrilase activity and preserving microbial cells with carbamate salts
A method for preserving immobilized or unimmobilized microbial cells having nitrilase activity and for stabilizing the nitrilase activity of unimmobilized or immobilized microbial cells has been...
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6664095 |
Solid state fermentation
The present invention provides an improved solid state fermentation device that combines all of the operations of microorganism cultivation (sterilization, inoculation, cultivation, extraction, and...
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6653135 |
Dynamic protein signature assay
An assay to determine the specific expression and suppression of proteins in response to a stressor is disclosed. An organism exposed to a stressor, including disease caused by exposure to, e.g., a...
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6646185 |
Genetic transformation method for zoysiagrass
The present invention provides an efficient genetic transformation system for the zoysiagrass plant ( Zoysia japonica Steud.). Also provided are optimized media compositions and culture conditions...
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6632649 |
Process for producing burkholderia cepacia in the presence of tert-butanol or tert-amyl alcohol, the inoculum produced, and a process for degrading said alcohols
The growth of the bacterium, Burkholderia cepacia (ex Pseudomonas cepacia ) CIP 1-2052 is substantially increased when it is supplied with tert-butanol (TBA) or tert-amyl alcohol (TAA) as the...
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6617126 |
Method for improving the growth and colorimetric detection of bacteria, yeasts, fungi or cocci
The present invention relates to a method for improving the growth and detection of bacteria, yeasts, fungi or cocci, by adding sterile-filtered yeast extract and/or p-iodonitrotetrazolium violet...
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6610530 |
Method of improving biomass yield of lactic acid bacterial cultures
A method of enhancing biomass yield of a lactic acid bacterial species cell culture, comprising cultivating the cells in a process comprising the steps of providing conditions that results in a...
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6589771 |
Methods for arousing dormant bacteria
A method for arousing dormant bacteria. The method comprises inducing diffusion of intracellular solutes from dormant bacteria and then allowing an adjustment period for a length of time sufficient...
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