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7615616 |
Bioinformatic method for identifying surface-anchored proteins from gram-positive bacteria and proteins obtained thereby
A bioinformatic method is provided for identifying and isolating proteins with MSCRAMM®—like characteristics from Gram positive bacteria, such as Enterococcus, Staphylococcus, Streptococcus ...
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7612019 |
Polypeptide display libraries and methods of making and using thereof
Disclosed herein are expression vectors which display a passenger polypeptide on the outer surface of a biological entity. As disclosed herein the displayed passenger polypeptide is capable of...
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7611885 |
Pharmaceutically compatible method for purifying intact bacterial minicells
The present invention provides a method for purifying bacterial minicells that involves subjecting a sample containing minicells to density gradient centrifugation in a biologically compatible...
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7608435 |
Microorganism producing 5′-xanthylic acid
The invention relates to a microorganism, obtained by treating Corynebacterium ammoniagenes KCCM 10488 producing 5′-Xanthylic acid as parent strain with UV radiation and mutation Derivatives...
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7601831 |
Methods, kits and assay system for detecting drug-resistant mycobacterium tuberculosis
The present invention relates to methods, kits and assay system for detecting drug-resistant Mycobacterium tuberculosis of suspected patient. The system of the present invention largely reduces...
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7588934 |
Gene encoding fumarate hydratase C and use thereof
A nucleotide sequence encoding a fumarate hydratase C and a method for preparing succinic acid using the same, more particularly, a fumarate hydratase C having the activity of converting malate to...
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7585957 |
Site specific system for generating diversity protein sequences
This invention relates to the diversification of nucleic acid sequences by use of a nucleic acid molecule containing a region of sequence that acts as a template for diversification. The invention...
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7582809 |
Sorghum aluminum tolerance gene, SbMATE
The major aluminum tolerance gene, the SbMATE gene, encodes a root citrate efflux transporter that is Al-inducible at the level of gene transcription and is also Al-activated at the level of...
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7579182 |
Use of cross-protection to identify novel vaccine candidates for infectious agents
This invention discloses methods for identifying Francisella tularensis vaccine candidates. It enables identification of novel vaccine candidates and quality assurance for vaccine batches,...
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7579009 |
Whole bacterial cells as immune modulator
An immune modulator composition and/or pharmaceutical composition comprising a whole cell of a bacterium from the genera Rhodococcus, Gordonia, Nocardia, Dietzia, Tsukamurella and Nocardioides ,...
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7575900 |
Non-reducing saccharide-forming enzyme, trehalose-releasing enzyme, and process for producing saccharides using the enzymes
A non-reducing saccharide-forming enzyme and a trehalose-releasing enzyme, which have an optimum temperature in a medium temperature range, i.e., a temperature of over 40 or 45° C. but below 60°...
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7575899 |
Microorganism of the genus Corynebacterium having enhanced L-lysine productivity and method of producing L-lysine using the microorganism of the genus Corynebacterium
The present invention provides a microorganism that belongs to the genus Corynebacterium and has an inactivated inherent NCgl2053 dehydrogenase gene, and a method of producing L-lysine using the...
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7575862 |
Assay systems, kits and methods for detecting microorganisms
The present invention relates to an assay system, kits and methods for detecting microorgansims (especially for M. tuberculosis ) of suspected patient. The present invention also relates to an...
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7572632 |
Dry powder cells and cell culture reagents and methods of production thereof
Methods and compositions involving nutritive media, media supplements, media subgroup and buffer formulations are provided. Powder buffer formulations that produce particular ionic and pH...
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7560541 |
Heart20049410 full-length cDNA and polypeptides
Novel full-length cDNAs are provided. cDNA derived from human have been isolated. The full-length nucleotide sequences of the cDNA and amino acid sequences encoded by the nucleotide sequences have...
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7560246 |
Compositions and methods for detecting target microorganisms in a sample
The present invention relates generally to compositions and methods for detecting target microorganisms in a sample. In particular, the present invention relates to compositions comprising a...
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7550139 |
Megasphaera elsdenii strain and its uses
This invention relates to a novel strain of Megasphaera elsdenii and its uses. This invention further relates to preparations and methods incorporating such strain. This invention also relates to...
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7547536 |
Method for detecting bacterial spores
A method of detecting the presence and quantity of bacterial spores, which includes adding an electrophilic alcohol and an acid anhydride to a sample, admixing the sample with a solvent, and...
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7544493 |
Method for the purification of an N-terminal fragment of hepatocyte growth factor
A method for the production of the N-terminal four kringle-containing fragment of hepatocyte growth factor (NK4) by expression of a nucleic acid encoding said NK4 in a microbial host cell,...
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7544492 |
OB polypeptides, modified forms and derivatives
The present invention relates generally to the control of body weight of animals including mammals and humans, and more particularly to materials identified herein as modulators of weight, and to...
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7541039 |
Immunization with bacterial ghost-based vaccines
Methods for improving binding of a proteinaceous substance to cell-wall material of a Gram-positive bacterium are disclosed. The proteinaceous substance includes an AcmA cell-wall binding domain,...
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7538206 |
Comparative mycobacterial geneomics as a tool for identifying targets for the diagnosis, prophylaxis or treatment of mycobacterioses
The present invention is directed to a method of selection of purified nucleotidic sequences or polynucleotides encoding proteins or part of proteins carrying at least an essential function for the...
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7537925 |
Mutated Lactococcus strain
A mutant of Lactococcus lactis spp. lactis , which produces lactate at high volumetric and specific productivity as well as high amounts of lactate dehydrogenase, as well as the use of said...
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7531344 |
Induction and stabilization of enzymatic activity in microorganisms
The present invention is directed to methods for inducing desired activity in enzymes or microorganisms capable of producing the enzymes. The invention is further directed to methods of stabilizing...
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7531163 |
Enrichment methods for the detection of pathogens and other microbes
The present invention provides novel enrichment, testing and detection methods for detection of pathogens or other microbes in a food, water, wastewater, industrial, pharmaceutical, botanical,...
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7524649 |
Modified growth hormone fusion polypeptides
The invention relates to chimeric polypeptides wherein said polypeptides comprise a modified binding domain of growth hormone linked to a receptor binding domain of growth hormone receptor; and...
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7514600 |
Stabilizing solutions for submicronic particles, methods for making the same and methods of stabilizing submicronic particles
Stabilizing solutions for submicronic particles, methods for making the same and methods of stabilizing submicronic particles is disclosed.
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7514403 |
Process for the stabilization of proteins in an aqueous solution comprising cysteine in a concentration between 150 and 220mM
The present invention relates to a process for the storage of proteins in an aqueous solution. The addition of cysteine delays the temporal decrease in the effective concentration of the protein....
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7504251 |
Bacterial strain, processed plant extracts, compositions containing same, processes for their preparation and their therapeutic and industrial applications
The present invention discloses: (i) a non-pathogenic probiotic microorganism and its probiotic/therapeutic uses; (ii) a formulation comprising an aqueous solution of a volatile fraction (VF)...
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7504236 |
Method to increase carotenoid production in a microbial host cell by down-regulating glycogen synthase
A method to increase carotenoid production in carotenogenic microbial host cells is provided by down-regulating or disrupting glycogen synthesis. Disruption of glycogen synthase activity in a...
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7501131 |
Haemophilus influenzae type IV pili
The invention described herein relates to a Haemophilus influenzae ( H. influenzae ) regulon encoding type IV pili. In particular, the invention relates to type IV pili from nontypeable H....
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7498155 |
Microbial nanowires, related systems and methods of fabrication
Conductive nanowires, as are available from a range of bacteria species, methods of use and related device structures.
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7495092 |
Compositions comprising promoter sequences and methods of use
Nucleic acid molecules, fragments and variants thereof having promoter activity are provided in the current invention. The invention also provides vectors containing a nucleic acid molecule of the...
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7491798 |
Scytovirins and related conjugates, fusion proteins, nucleic acids, vectors, host cells, compositions, antibodies and methods of using scytovirins
An isolated or purified antiviral protein of SEQ ID NO: 1, nucleic acids encoding the antiviral protein, cells comprising the nucleic acids, and methods of inhibiting viral infection comprising...
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7491386 |
Treatment of actinomyces naeslundii-related diseases with exogenous lactic bacteria strains
A lactic bacteria strain that is exogenous to the oral microflora is selected for its ability to adhere the pellicle of the teeth and to produce a growth inhibition factor. This strain is used for...
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7485290 |
Compositions containing bacterium capable of converting lactic acid into butyric acid and method of preventing/treating hyperlactic acidemia in digestive tract and colon cancer by using the same
A composition comprising Megasphaera elsdenii strain JCM1772 or strain iNP-001. The compositions may optionally contain live or processed bacterial products. A method for decreasing lactate...
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7482140 |
L-tyrosine-producing bacterium and a method for producing L-tyrosine
The present invention describes the production of L-tyrosine by culturing in a medium an Escherichia bacterium which has L-tyrosine-producing ability and which carries a mutant prephenate...
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7476516 |
Methods for producing biological substances in pigment-deficient mutants of Bacillus cells
The present invention relates to methods of producing a heterologous biological substance, comprising: (a) cultivating a mutant of a parent Bacillus cell under conditions conducive for the...
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7476391 |
Anti-bacterial vaccine compositions
Gram negative bacterial virulence genes are identified, thereby allowing the identification of novel anti-bacterial agents that target these virulence genes and their products, and the provision of...
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7465855 |
Non-toxic endophytes, plants injected therewith and methods for injecting plants
A grass with improved environmental stress tolerance and low animal toxicity is disclosed where the grass is infected with an isolated endophyte selected from the groups consisting of USDA-PI no....
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7452721 |
Practical serological assay for the clinical diagnosis of leishmaniasis
Methods for the diagnosis of visceral, cutaneous and canine leishmaniasis in a subject suspected of being infected with the parasitic protozoa Leishmania is disclosed. Disclosed are...
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7449327 |
System and method for dispensing dehydrated culture media powder
An improved system and method for dispensing dehydrated culture media (DCM) powder into containers for preparation as a culture media. The manual and automated systems and methods operate to...
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7445895 |
Methods, kits and assay system for detecting drug-resistant Mycobacterium tuberculosis
The present invention relates to methods, kits and assay system for detecting drug-resistant Mycobacterium tuberculosis of suspected patient. The system of the present invention largely reduces...
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7442541 |
β-glucan-containing fat and oil composition and novel microorganism capable of producing β-glucan
A β-glucan-containing fat and oil composition contains β-glucan of microorganism origin or basidiomycete origin. The β-glucan-containing fat and oil composition has β-glucan uniformly dispersed...
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7442538 |
Modular system comprising multiple automated mini-bioreactors for high-throughput screening (HTS) in biotechnology
The invention relates to a method and a device which are used to obtain and maintain multiple biological cultures, with environmental parameters similar to those of larger bioreactors (from 1 L)...
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7440160 |
Electro-optical light modulating element, electro-optical display and modulating medium
The invention relates to electrooptical light modulating elements, to electrooptical displays containing elements of this type, and to display systems, e.g. television screens and computer...
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7435878 |
Method for altering the male fertility of plants
A method for altering fertility of a plant or modifying its structure is described. The method comprises, in any order, contacting the seed of the plant with Pink-Pigmented Facultative Methylotroph...
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7435560 |
Method for producing purine nucleoside by fermentation
A microorganism which has a gene encoding an enzyme in which feedback inhibition is desensitized by substitution of one or two amino acids in PRPP amidotransferase encoded by purF of Escherichia...
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7425440 |
Culture flask
A culture flask 10 comprises two or more internal chambers 18 - 21 defining a plurality of parallel surfaces of different sizes and means for fluid communication 24 between the chambers 18 -...
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7422871 |
Uropathogenic E. coli D-serine detoxification operon
Disclosed are methods of detecting uropathogenic E. coli genes that are differentially expressed in response to D-serine. Also disclosed are methods of characterizing bacterial isolates from...
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