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6673540 |
Cell systems having specific interaction of peptide binding pairs
This invention relates to modified host cells which express heterologous fused proteins and methods of screening for test samples having peptide binding activity; wherein the modified host cell...
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6673538 |
Methods and compositions for designing vaccines
Methods and compositions are described for determining a statistically significant number of different strains within a species of bacteria indicative of the species population structure as a whole...
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6669969 |
Pesticidal use of a parasitic flagellate for eliminating or suppressing harmful algae blooms
The present invention related to Parvilucifera infectans , a new parasitic organism described by Noren and Moestrup (in prep. “ Parvilucifera infectans , gen. et. spec.nov. A parasitic...
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6664096 |
Methods for improved diagnosis and treatment of mycobacterial infections
Media for growth enhancement and resuscitation of mycobacteria (such as Mycobacterium tuberculosis, Mycobacterium paratuberculosis , and Mycobacterium leprae ) are provided. The media comprise...
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6664095 |
Solid state fermentation
The present invention provides an improved solid state fermentation device that combines all of the operations of microorganism cultivation (sterilization, inoculation, cultivation, extraction, and...
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6664094 |
Neisserial vaccine free of immunologically functional PIII or class 4 proteins
This invention relates to mutants of Neisseria useful for vaccine preparation. Specifically this invention relates to mutants of Neisseria containing mutations in a major outer membrane protein...
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6664078 |
Method for the isolation of ccc plasmid DNA
The present invention relates to the production of biomass for the isolation of ccc plasmid DNA comprising culturing a bacterial transformant in a bioreactor containing an antibiotic-free batch...
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6664076 |
Modification of bacteria
Sporulation-deficient variants of thermophilic, facultatively anaerobic, Gram-positive bacteria can be generated using a plasmid transformation system based on a novel method of in vivo...
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6660516 |
Method for culturing a microorganism and promoting microbial growth and metabolism
A method is provided for culturing a microorganism in a culture medium containing a carbon source and an electrolyzed water containing not more than 0.4 ppm chlorine produced during electrolyzing...
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6660515 |
Method of improving the efficacy of lactic acid bacterial starter cultures and improved starter culture compositions
Methods of enhancing the growth rate and/or controlling the metabolic activity of lactic acid bacteria and of improving the shelf life and/or the quality of an edible product using lactic acid...
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6660508 |
Dietary supplements for treating hyperlipemia
Compositions comprising a plurality of yeast cells, wherein said plurality of yeast cells are characterized by their ability to treat hyperlipemia (e.g., regulate triglyceride and/or...
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6660269 |
Homologous 28-kilodalton immunodominant protein genes of Ehrlichia canis and uses thereof
The present invention is directed to the cloning, sequencing and expression of homologous immunoreactive 28-kDa protein genes, p28-1, -2, -3, -5, -6, -7, -9, from a polymorphic multiple gene family...
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6660263 |
Oocydin and methods of use for protection of plants from Oomyocyte pathogens
Oocydin A is a mono-chlorinated lipophilic macrocyclic lactone that was isolated from a strain of Serratia marcescens that produces oocydin A in culture. Oocydin A has a molecular mass of 470,...
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6656714 |
Nucleic acids and proteins of a rat ganglioside GM1-specific α1→2 fucosyltransferase and uses thereof
A rat ganglioside GM 1 -specific α1→2fucosyltransferase is disclosed. Nucleotide sequences of a rat ganglioside GM 1 -specific α1→2fucosyltransferase, amino acid sequences of its encoded...
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6656703 |
High throughput screen for inhibitors of fatty acid biosynthesis in bacteria
Methods for identifying compounds that are inhibitors of bacterial fatty acid biosynthesis are disclosed. Such compounds can be used as lead compounds in methods for preparing antibacterial agents...
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6656478 |
Cross-protective salmonella vaccines
The present invention relates to a method of protecting pigs against disease caused by infection by heterologous serotypes of Salmonella including but not limited to S. typhimurium comprising...
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6653135 |
Dynamic protein signature assay
An assay to determine the specific expression and suppression of proteins in response to a stressor is disclosed. An organism exposed to a stressor, including disease caused by exposure to, e.g., a...
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6653111 |
Bacterial strain of Escherichia coli BKIIM B-3996 as the producer of L-threonine
The present invention provides a method for deriving an E. coli strain which produces L-theronine from E.coli strain VNIIgenetika 472T23 by transducing with bacteriophage P1 which bears a...
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6652849 |
Anaerobe targeted enzyme mediated prodrug therapy
A genetically-engineered anaerobic organism is provided which, under anaerobic conditions present in a solid tumor, produces an enzyme capable of catalyzing the conversion of a prodrug to its...
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6649408 |
Microdroplet cell culture technique
The present invention comprises a novel culture method and device in which living cells are cultured in a plurality of individual microdroplets that are immobilized and isolated within a matrix of...
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6649405 |
Compost tea system
A compost tea system uses a water-holding tank for containing process water. Compost is immersed into the water in the tank in baskets defining a filter media. Air is pumped into membrane disk...
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6649398 |
Method for inducing bacterial growth using autoinducers
A bacterial autoinducer and method for isolating and purifying a bacterial autoinducer form a sample comprising the steps of collecting a sample containing the autoinducer, fractionating the sample...
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6649397 |
MICROBIAL CULTURE LIQUORS CONTAINING MICROORGANISMS DIFFERING IN CHARACTERISTICS AND LIVING IN SYMBIOSIS AND METABOLITES THEREOF, CARRIERS AND ADSORBENTS CONTAINING THE ACTIVE COMPONENTS OF THE CULTURE LIQUORS AND UTILIZATION OF THE SAME
Solutions containing microorganisms differing in characteristics from each other and living in symbiosis with each other and enzymes characterized by containing aerobic microorganisms, anaerobic...
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6649383 |
Dietary supplements beneficial for the gastrointestinal system
Compositions comprising a plurality of yeast cells, wherein said plurality of yeast cells are characterized by their ability to increase secretion of gastric juice or alleviate gastric ulcer in a...
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6649379 |
Method and deregulated enzyme for threonine production
Mutagenesis of the gene encoding homoserine dehydrogenase (hom) for production of the amino acid threonine is described. The mutation causes an alteration in the carboxy terminus of the enzyme that...
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6645761 |
Humanized polynucleotide sequence encoding Renilla mulleri green fluorescent protein
The present invention provides a polynucleotide encoding a green fluorescent protein from Renilla mulleri comprising a humanized sequence which permits enhanced expression of the encoded...
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6645739 |
Yeast expression systems, methods of producing polypeptides in yeast, and compositions relating to same
The present invention provides novel expression systems for producing desired polypeptides in certain strains of yeast. The present invention further provides methods for producing polypeptide...
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6642031 |
Microorganisms with ability to degrade indole and enzymes therefrom
There is provided novel indole oxidase activity isolated from P. putida , such indole oxidase activity is believed to be useful in the biosynthetic production of indigo from its precursor indole....
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6638738 |
Isolated human lipase proteins, nucleic acid molecules encoding human lipase proteins, and uses thereof
The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the lipase peptides of the present invention. The present invention specifically...
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6635471 |
Temperature control of incubation vessels using electrically conducting polymers
The use of incubation means for the controlled heating of biological materials, said means comprising an electrically conducting polymer connectable to a power supply, said polymer being either...
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6635467 |
Monascus purpureus mutant and its use in preparing yellow pigment
The invention relates to a mutant of Monascus purpureus , designated as Monascus purpureus M011, which is useful in the production of yellow pigments with a low amount of citrinin.
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6632666 |
Normothermic, hypothermic and cryopreservation maintenance and storage of cells, tissues and organs in gel-based media
Gel-based medium compositions and a method of use thereof in normothermic, hypothermic or cryopreservative storage and transport of cell samples are described. These gel-based compositions contain...
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6632439 |
Fusobacterium necrophorum vaccine and method for making such vaccine
The present invention relates to a method of producing a vaccine for the prevention of F. necrophorum bacterial infections, comprising isolating the F. necrophorum bacteria from a bovine...
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6630457 |
Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same
Methods for chemical modification of hyaluronic acid, formation of amine or aldehyde functionalized hyaluronic acid, and the cross-linking thereof to form hydrogels are provided. Functionalized...
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6627747 |
Essential bacterial genes and their use
Disclosed are two genes, termed “yphC” and “yqjK,” found in Streptococcus pneumoniae , which are essential for survival for a wide range of bacteria. These genes and the essential...
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6627429 |
Process for enzymatically modifying pectin
A process for treating a pectin with a pectin methyl esterase (PME) is descibed. Here, the PME is not a plant PME—but the PME is capable of exhibiting at least one plant PME property; wherein the...
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6627426 |
Methods for reducing adventitious agents and toxins and cell culture reagents produced thereby
The present invention relates generally to a method to reduce, substantially reduce, inactivate or eliminate adventitious agents and/or toxins in a sample, particuarly in nutritive media, media...
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6627203 |
Renibacterium salmoninarum vaccine
The invention provides an immune stimulating agent or vaccine directed to Renibacterium salmoninarum comprising a live non-virulent culture of an Arthrobacter strain based on, derived from or...
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6623961 |
Method for selective inactivation of viral replication
Method for screening for an antiviral agent, by determining whether a potential agent interacts with a virus or cellular component which allows or prevents preferential translation of a virus RNA...
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6620611 |
Solid-chemical composition for sustained release of organic substrates and complex inorganic phosphates for bioremediation
A slow-release solid chemical composition for environmental bioremediation is provided. The composition comprises a source of soluble organic substrates which include sugars, soluble organic...
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6620609 |
Process of microwave sterilization of culture media for selection of recombinant microorganisms
The invention relates to a process for a simplified and rapid preparation of sterile culture media using microwave ovens. The sterile media of the invention are usable for the selection and...
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6617163 |
Polynucleotides for mutagenesis in fungus comprising a functional gene in magnaporthe and an impala transposon
The invention concerns a new tool for efficient mutagenesis enabling the generation of a collection of mutants in fungi by random insertion of a characterized Fusarium oxysporum Impala transposon...
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6617151 |
Method of closing a cell containment device with a wet seal
A method is provided for closing a containment device that involves wetting at least a portion of a permeable polymeric membrane such as tubular membrane with a liquid such as a cell suspension or...
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6617148 |
Natural promoters for gene expression and metabolic monitoring in bacillus species
Genes have been identified in the Bacillus genome that are responsive to various metabolic conditions and growth cycle changes. The new responsiveness of these genes allows for their use in...
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6617146 |
Method and apparatus for automatically inoculating culture media with bacterial specimens from specimen containers
A method and system are provided for automatically positioning specimen containers and culture medium containers and transferring specimen samples from the containers to the culture medium. The...
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6617131 |
Nucleic acid molecule encoding the potassium channel protein, KCNQ5
KCNQ5, DNA encoding KCNQ5 or a polypeptide having KCNQ5 activity, related vectors, host cells and methods and a screening assay for identification of compounds which modify activity of a potassium...
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6617128 |
Nucleic acid molecules encoding proteins which impart the adhesion of neisseria cells to human cells
Described are nucleic acid molecules encoding proteins mediating the adhesion of bacteria of the genus Neisseria to human cells. Also described are the proteins encoded by these nucleic acid...
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6613555 |
32142, 21481, 25964, 21686, novel human dehydrogenase molecules and uses therefor
The invention provides isolated nucleic acids molecules, designated DHDR nucleic acid molecules, which encode novel DHDR-related dehydrogenase molecules. The invention also provides antisense...
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6613545 |
Nucleotide sequences coding for the export of branched chain amino acids, process for the isolation thereof and use thereof
This invention relates to isolated polynucleotides containing at least one of the polynucleotide sequences selected from the group a) polynucleotide which is at least 70% identical to a...
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6611766 |
Proteome analysis for characterization of up-and down-regulated proteins in biological samples
Methods and computer systems are provided for analyzing cell proteomes to characterize proteins that are up- or down-regulated under different conditions, such as under abnormal or compound treated...
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