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6835384 |
Nucleic acids and polypeptides specific of the neisseria genus pathogenic strains
The invention concerns nucleic acids coding for polypeptides specific of the Neisseria genus pathogenic strains, the corresponding polypeptides, and their diagnostic and therapeutic applications.
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6833260 |
Lactose hydrolysis
The invention features methods and compositions for rapidly and effectively hydrolyzing lactose using recombinant lactic acid bacteria.
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6830885 |
Nucleic acid molecule, method and kit for selecting a nucleic acid having a desired feature
This invention relates to the screening of nucleic acids. More particularly, the present invention provides a dysfunctional viral genome capable of both expressing libraries of exogenous nucleic...
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6828131 |
Biological fertilizer based on yeasts
The present invention provides biological fertilizer compositions that comprise yeast cells that have an enhanced ability to fix atmospheric nitrogen, decompose phosphorus minerals and compounds,...
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6825016 |
α-glycated amino acid releasing enzyme
The present invention relates to a novel enzyme (α-GARE) which releases an amino acid residue having a glycated α-amino group (α-GA) from a glycated protein etc. and to bacterial strains...
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6824996 |
Production of ascorbic acid
The present invention provides for the production of ASA from yeast capable of producing ASA from KLG. The present invention provides methods for the production of ASA as well as recombinant yeast...
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6815414 |
Pharmaceutical compositions for the treatment of helicobacter pylori-associated disorders
The invention relates to pharmaceutical compositions and methods for treating and/or preventing Helicobacter pylori -associated disorders, particularly disorders of the gastrointestinal tract. The...
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6815180 |
Human cervical cancer 1 protooncogene and protein encoded therein
A human cervical cancer 1 protooncogene having a base sequence of SEQ ID:1 or a fragment thereof is overexpressed in various cancer tissues and can be used in diagnosing various cancers and an...
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6815183 |
Plasmodium sp. chitinase
The present invention is directed to isolated nucleic acid molecules encoding Plasmodium sp. chitinases . Expression vectors and host cells comprising the nucleic acid molecules are also...
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6815591 |
Enhancing endophyte in grass
The present invention relates to plants that are stably infected with an endophyte fungus. The purpose in providing to plants unique fungal endophytes is to import desired traits. These traits...
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6812004 |
Mammalian dendritic cell chemokine reagents
A novel CC chemokine which is from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding said chemokine. Methods of using said reagents and...
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6811787 |
Over-expressing homologous antigen vaccine and a method of making the same
This invention relates to an over-expressing homologous antigen vaccine, a method of producing the same, and use of the vaccine for prophylaxis or treatment of vertebrates at risk of or suffering...
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6809081 |
Chemotherapeutic composition and method
The present invention relates to a composition and method comprising Mycobacterium phlei ( M. phlei )-DNA (M-DNA), M-DNA preserved and complexed on M. phlei cell wall (MCC), a chemotherapeutic...
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6808896 |
Method for stable chromosomal multi-copy integration of genes
The present invention solves the problem of integrating multiple copies of a gene of interest by homologous recombination into well defined positions adjacent to conditionally essential genes in a...
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6806081 |
Methods and organisms for concentrating and recovering metals and minerals from aqueous media
The present invention relates to methods and organisms for concentrating and recovering metals and minerals from aqueous media. In the inventive method, a eucaryotic aquatic organism capable of...
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6806078 |
Substrate and method for anaerobic remediation
The present invention comprises a method for anaerobic remediation of contaminated soil and groundwater comprising (a) preparing an aqueous mixture of a sparingly soluble digestible fat or oil, (b)...
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6806065 |
Rickettsia felis outer membrane protein
The present invention is directed to isolated nucleic acid molecules encoding Rickettsia felis outer membrane proteins ( R. felis omp). Expression vectors and host cells comprising the nucleic...
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6806082 |
Isolated nucleic acid molecule encoding a regulator of fungal gene expression
The invention relates to regulators of fungal gene expression and their use in commercial and medical applications. More particularly, the invention relates to regulators of fungal genes involved...
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6800476 |
Regulated expression of PKC and/or SRB1/psa1 in yeast
The present invention relates to yeast cells containing the SRB1/PSA1 gene and/or the PKC1 gene or functional derivatives thereof operatively linked to a heterologous inducible promoter and also to...
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6800466 |
Biological fertilizer compositions comprising sludge
The present invention provides biological fertilizer compositions that comprise yeast cells and sludge. The yeast cells of the invention have an enhanced ability to fix atmospheric nitrogen,...
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6797507 |
Methods of using worm castings for fungal control
The present invention describes a material and a method for controlling fungi. The method consists of disposing a naturally formed chitinase about an area to be protected. The naturally formed...
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6797273 |
Neisseria meningitidis antigen
The invention provides BASB053 polypeptides and polynucleotides encoding BASB053 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic,...
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6797508 |
Bioreactor for fermenting solids
The invention relates to bioreactor for fermenting solid substrates, comprising a fermentation vessel ( 2 ), a device for feeding bioreactive substances and a nozzle arrangement in the fermentation...
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6794156 |
Cell growth, induction and lysis in an antibody-coated microplate for use in an ELISA
A competitive assay to determine the presence and concentration of an intracellular analyte (e.g., cAMP) in a sample is provided. All of the steps of the assay can be performed on the same assay...
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6793917 |
Type CC chemokine-like protein
An isolated novel type CC chemokine-like protein which is expressed from peripheral blood mononuclear cells under an immunological stimulus and has a cell migration activity; a DNA encoding the...
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6793927 |
Construction of Pasteurella haemolytica vaccines
Methylation of DNA can be a critical step in the introduction of DNA into P. haemolytica . A methyltransferase has been isolated and molecularly cloned for this purpose. Use of the...
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6793933 |
Dietary supplements for enhancing the immune system
Compositions comprising a plurality of yeast cells, wherein said plurality of yeast cells are characterized by their ability to enhance the immune system (e.g., increase the activity of T and B...
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6794162 |
Phage-dependent super-production of biologically active protein and peptides
This invention relates to a method for enhancing the production of biologically active proteins and peptides in bacterial cells by infecting bacterial cells of the producer strain, which contain a...
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6787340 |
Apparatus for separating cells and producing microbial polysaccharides
The present invention includes a process for separating cells from a liquid media, a method of fermentation using such a separation, and an apparatus for conducting such a separation or for...
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6787347 |
Process for the preparation of amino alcohols and derivatives thereof and microorganisms useful in process
The invention relates to a novel process for the preparation of (1R,4S)- or (1S,4R)-1-amino-4-(hydroxymethyl)-2-cyclopentene of the formulae and/or of (1S,4R)- or (1R,4S)-amino alcohol...
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6787336 |
DNA encoding growth hormone antagonists
The present invention relates to DNA molecules which encode antagonists of vertebrate growth hormones obtained by mutation of at least the amino acid corresponding to Glu-119 in bovine growth...
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6783985 |
Gene disruption methodologies for drug target discovery
The present invention provides methods and compositions that enable the experimental determination as to whether any gene in the genome of a diploid pathogenic organism is essential, and whether it...
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6780612 |
Methods for the propagation of lytic organisms
The present invention provides a method for the propagation of lytic organisms which comprises the infection of the cells of a stable cell line within a hollow fibre bioreactor with a lytic...
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6780613 |
Growth hormone variants
The invention provides methods for the systematic analysis of the structure and function of polypeptides by identifying active domains which influence the activity of the polypeptide with a target...
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6773910 |
Method of preparing (S)- or (R) -3,3,3-trifluoro-2-hydroxy-2-methylpropionic acid
Described are new micro-organisms and a new enzyme capable of using as sole source of nitrogen the propionic acid amide of formula (VI), in racemate form or as optically active isomers. Described...
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6770284 |
Polypeptides and polynucleotides BASB040 from neisseria meningitidis and vaccine comprising said polypeptides and polynucleotides
The invention provides BASB040 polypeptides and polynticleotides from Neisseria meningitidis encoding BASB040 polypeptides and methods for producing such polypeptides by recombinant techniques....
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6770481 |
Gene isolation method
A plasmid vector characterized by comprising a promoter sequence that can be recognized by an RNA polymerase which is not inherent in a host and that controls the expression of desired genes and a...
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6768001 |
Xylanase from trichoderma reesei, method for production thereof, and methods employing this enzyme
The present invention is directed to novel xylanases (referred to as XYL-IV) and to nucleic acid molecules encoding those xylanases. Also provided herein are vectors and host cells including those...
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6767722 |
Analogs of human basic fibroblast growth factor mutated at one or more of the positions glutamate 89, Aspartate 101 or Leucine 137
The present invention relates to muteins of human basic fibroblast growth factor with superagonist properties. Both protein and the respective encoding nucleic acid species are disclosed. The...
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6764687 |
Live attenuated bacteria for use in a vaccine
The present invention relates to live attenuated bacteria for use as a medicament. The invention also relates to vaccines based thereon that are useful for the prevention of microbial pathogenesis....
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6762040 |
Method for increasing gene copy number in a host cell and resulting host cell
The invention relates to a method for increasing the copy number of a chromosomally integrated expression cassette in a microbial strain without leaving antibiotic resistance markers behind in the...
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6759230 |
Microbe, microbial exopolysaccharide, and uses thereof
A novel microorganism producing a nontoxic, non-antigenic exopolysaccharide is taught. The exopolysaccharide has neutral sugars migrating at the same rate as mannose, fucose, fructose and...
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6759209 |
Bacillus strain and assay methods
Micro-organisms having a chromosome in which at least one gene has been partly or wholly replaced by a homologous gene from another micro-organism, and an artificially introduced reporter gene is...
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6759055 |
Dietary supplements for improving kidney function
Compositions comprising a plurality of yeast cells, wherein said plurality of yeast cells are characterized by their ability to improve kidney functions (e.g., restoring urine secretion and/or...
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6759215 |
Method of preparing human stem cell factor polypeptide
Novel stem cell factors, oligonucleotides encoding the same, and methods of production, are disclosed. Pharmaceutical compositions and methods of treating disorders involving blood cells are also...
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6756050 |
Dietary supplements for improving memory
Compositions comprising a plurality of yeast cells, wherein said plurality of yeast cells have been cultured in the presence of an alternating electric field having a specific frequency and a...
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6756222 |
Escherichia coli having accession No. PTA 1579 and its use to produce polyhydroxybutyrate
The present invention provides a novel genetically modified Escherichia coli JM109 bearing accession number PTA 1579, containing the gene coding for poly-beta-hydroxybutyrate synthesis and a...
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6753008 |
Dietary supplements beneficial for the liver
Compositions comprising a plurality of yeast cells, wherein said plurality of yeast cells are characterized by their ability to normalize the serum level of GPT, AP and/or LDH-5 in a mammal, said...
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6752994 |
Insertional mutations in mycobacteria
A mutated mycobacterium selected from the class consisting of mutated M. bovis -BCG, mutated M. tuberculosis, and mutated M. leprae . The mutation of M. bovis -BCG, M. tuberculosis, or M....
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6750051 |
Compositions and methods for enhancing fiber digestion
Methods and enzyme supplements for enhancing fiber digestion in mammals and birds are described. The supplement comprises an effective amount of acetyl esterase, formulated for feeding to animals...
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