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6177084 |
S. aureusfibrinogen binding protein
The isolation of the S. aureus fibrinogen binding protein gene is described and a minimal fibrinogen binding protein is identified. The protein finds use as a vaccine or a pharmaceutical...
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6174717 |
Elicitor of the hypersensitive response in plants
The nucleic acid and amino acid sequences for proteinaceous elicitors of the plant defense reaction known as the hypersensitive response are described along with methods for preparation and...
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6173527 |
Method for treatment of top soil of a field with ozone gas to increase growth of plants
An ozone containing gas is injected into a portion of top soil that was previously oversaturated with water, to stimulate the propagation and growth of living organisms. The injected ozone oxidizes...
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6171805 |
DNA and host cells encoding a cell surface protein of Porphyromonas gingivalis
A DNA encoding a cell surface polypeptide of Porphyromonas gingivalis, and a recombinant DNA being a DNA having integrated said DNA thereinto. The cell surface polypeptide of the periodontopathic...
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6165472 |
folC from Streptococcus pneumoniae
The invention provides folC polypeptides and DNA (RNA) encoding folC polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing folC...
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6162633 |
Process and kit for fragment cloning
The subject matter of the invention concerns three cosmid vectors which are suitable for fragment cloning of a size between 7 and 36 kb. These vectors consist of an E. coli ColE1 replica, an...
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6159696 |
Isolated human BMP-4 promoter region
The isolated human bone morphogenic protein-4 (BMP-4) promoter region, a vector comprising the isolated promoter region, and host cells comprising the isolated promoter region is described. A...
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6156516 |
Method for screening substance inhibiting activation of NF-κB
An expression regulatory sequence comprising a NF-κB recognition sequence, at least part of the 3'-untranslated region (3'-UTR) and at least part of the 3'-flanking region of human induced...
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6156540 |
Thrombin inhibitor
There is provided a thrombin inhibitor polypeptide and DNA(RNA) encoding such polypeptide. Also provided is a procedure for producing such polypeptide by recombinant techniques. The anti-thrombin...
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6153422 |
Oxygen absorber for culturing anaerobic bacteria
An oxygen absorber is provided which is obtainable by mixing 10 to 60 parts by weight of a particulate thermoplastic resin having a softening point of 90 to 125° C. and a particle diameter of 1 to...
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6153435 |
Nucleic acid that encodes a chimeric adenoviral coat protein
The present invention provides a chimeric adenoviral coat protein (particularly a chimeric adenovirus hexon and/or fiber protein). The chimeric adenovirus coat protein has a decreased ability or...
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6150589 |
Genes encoding lepidopteran-active toxins from Bacillus thuringiensis isolate PS158C2
Novel B.t. genes encoding toxins active against lepidopteran insects have been cloned from a novel lepidopteran-active B. thuringiensis isolate P515862. The DNA encoding the B.t. toxin can be used...
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6149929 |
Green water inhibitor-GWI
A composition for effective algae control comprising bacteria and humic acid made by extracting the liquid from barley straw soaked in water for a period of time.
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6150133 |
Fermentation control
A process of culturing a microorganism in a culture medium in which process the addition of feed medium is controlled by using the production of a by-product as a measure of the culture conditions,...
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6146878 |
Tyrosine repressor gene of a bacterium belonging to the genus Erwinia
Using as a host Escherichia coli which expresses lactose operon under the control of the promoter/enhancer of tyrosine phenol lyase gene derived from Erwinia herbicola, a DNA fragment coding for...
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6146851 |
DNA encoding NV2 (long form) and carboxy truncated fragments thereof
A colony stimulating factor, CSF-1, is a lymphokine useful in regulating the immune system is a lymphokine useful in overcoming the immunosuppression induced by chemotherapy or resulting from other...
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6146876 |
22025, a novel human cyclic nucleotide phosphodiesterase
The present invention relates to a newly identified human cyclic nucleotide phosphodiesterase belonging to the superfamily of mammalian phosphodiesterases. The invention also relates to...
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6143523 |
Human growth hormone variants
Human growth hormone variants and their nucleic acids are disclosed wherein the amino acid residues at positions 10, 14, 18, 21, 167, 171, 174, 176 and 179 have been replaced with other amino...
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6140123 |
Method for conditioning and cryopreserving cells
A method is provided for preconditioning and cryopreservation of cells harvested from a donor. Cells are suspended in a cell conditioning and cryopreservation medium containing a cryopreservative...
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6140078 |
Salt-inducible promoter derivable from a lactic acid bacterium, and its use in a lactic acid bacterium for production of a desired protein
The invention provides a salt-inducible promoter present in SEQ ID NO: 10 and derivable from a lactic acid bacterium in isolation from the coding sequence normally controlled by said promoter in a...
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6139833 |
Targeted gene discovery
The present invention describes a comprehensive system for gene discovery using retrovirus that have been engineered to exhibit increased accessibility to genomic DNA, or to mutate and identify the...
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6136597 |
RNA export element
A cis-acting posttranscriptional regulatory element (PRE) useful for efficient RNA export of RNA is provided. The element termed WPRE, is originally derived from woodchuck hepatitis virus. The...
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6136554 |
Microbiological media for isolation and indentification of enteric pathogens such as E. coli and salmonella
The present invention is directed to methods and media for the growth, enrichment, isolation, and presumptive identification of enteric pathogens such as E. coli 0157:H7 and Salmonella. In...
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6136563 |
Human growth hormone variants comprising amino acid substitutions
Human growth hormone variants are disclosed having enhanced affinity for the growth hormone receptor. Also disclosed are human growth hormone variants conjugated to one or more chemical groups,...
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6132709 |
Bacterin for the treatment of necrophorum diseases and a method for the production thereof
A method for treating cattle and sheep to prevent foot rot and/or liver necrosis comprising administering a Fusobacterium necrophorum bacterin which is a β-propriolactone inactivated Fusobacterium...
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6130080 |
Roller bottle having pitted or cratered inner surface for cell growth
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6126839 |
Use of an alcohol-salt buffer wash for the efficient recovery of mycobacteria and mycobacterial DNA from respiratory sediment
The present invention relates to methods for concentrating bacteria from a viscous biological sample. The methods involve adding to the sample a water-soluble, density-lowering agent having a...
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6127169 |
Non-agglutinating β-galactoside binding protein and its encoding nucleic acid
Non-agglutinating β-galactoside binding proteins (GBP), both the natural proteins and proteins produced by recombinant DNA technology, are provided for use as inhibitors and regulators of...
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6127167 |
Method of controlling proliferation of aerobe
Disclosed herein is a method of controlling the proliferation of an aerobe, in which in the continuous culture of the aerobe by supplying a substrate and oxygen to a culture tank of the aerobe to...
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6114515 |
PIGRL-1, a member of immunoglobulin gene superfamily
PIGRL-1 polypeptide and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing PIGRL-1 polypeptide and...
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6114161 |
Antitumor preparations
A new bacteria species within the genus Streptococcus is disclosed, designated as Streptococcus sp PT DSM 8747. From this bacteria species a lipoteichoic acid LTA can be isolated which has a lipid...
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6110738 |
Human fast-1 gene
hFAST-1 is a human forkhead activin signal transducer gene. The hFAST-1 protein has the ability to bind to human Smad2 and activate an activin response element (ARE). The hFAST-1-dependent...
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6111074 |
PyrH of Streptococcus pneumoniae
The invention provides pyrH polypeptides and polynucleotides encoding pyrH polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for...
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6100043 |
Recombinant clone selection system
Cloning systems useful for the isolation of recombinant nucleic acid are disclosed in which the recombination of cloning-system nucleic acid and foreign nucleic acid is linked to the expression of...
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6093559 |
Producing low binding hydrophobic surfaces by treating with a low HLB number non-ionic surfactant
Hydrophobic polymer surfaces whose level of protein binding is less than about 50-80 ng/cm 2 are achieved by: (1) applying to a hydrophobic polymer surface a coating solution composed of a solvent...
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6093808 |
IκBEGFP constructs, cell lines and methods of use
The present invention provides fusion protein comprising IκB and green fluorescent protein. Also provided is DNA encoding this protein and vector expressing such DNA and various methods of using a...
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6093394 |
Vaginal lactobacillus medicant
Disclosed are novel isolated strains of bacteria of the genus Lactobacillus which are useful in a vaginal medicant. Also disclosed are medicants containing such Lactobacilli, a novel preservation...
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6087155 |
On site microbial bioremediation system and method of using said system
An on site bioremediation system that delivers logarithmically growing, active microorganisms from the culture vessel directly to the biodegradable waste to be metabolized is disclosed. The system...
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6087563 |
Cloned arabidopsis p-hydroxyphenyl pyruvic acid dioxygenase DNA
A cDNA clone from Arabidopsis thaliana, pHPP1.5, SEQ ID NO:1, which encodes the enzyme p-hydroxyphenyl pyruvic acid dioxygenase, is disclosed. A vector and microbial host containing a DNA sequence...
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6083721 |
Isolated nucleic acid molecules encoding PARG, a GTPase activating protein which interacts with PTPL1
The invention describes nucleic acids encoding the PARG protein, including fragments and biologically functional variants thereof. Also included are polypeptides and fragments thereof encoded by...
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6077678 |
Methods for detecting Campylobacter bacteria or antibodies to Campylobacter bacteria with an immunoassay
This invention relates generally to in vitro methods for inducing or enhancing expression of enteric bacterial antigens and/or virulence factors thereby producing antigenically enhanced enteric...
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6077515 |
Flagella-less borrelia
This invention relates to flagella-less strains of Borrelia and to novel methods for use of the microorganisms as vaccines and in diagnostic assays. Although a preferred embodiment of the invention...
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6071910 |
Use of agents to treat eosinophil-associated pathologies
A therapeutic method comprising counteracting or preventing pathologies mediated by IL-5, including those characterized by eosinophil infiltration, degranulation and inflammation, by administering...
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6071713 |
Bioprocesses for preparing 7-ACA and 7-ADAC
A bioprocess for preparing adipoyl-7-ACA comprising the steps: (a) transforming cells of a strain of Penicillium chrysogenum which produces isopenicillin N with an expression vector containing DNA...
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6069010 |
High throughput gene inactivation with large scale gene targeting
The present invention provides a vector system that is useful for the generation of mutations in a recombination-based construction method. The invention further includes the incorporation of...
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6069301 |
Antibodies which bind to insect gut proteins and their use
Antibodies, monoclonal antibodies or fragments thereof which bind to brush border membrane vesicles of insect gut and the gene or genes which encode these proteins are provided. The monoclonal...
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6060067 |
Process for the preparation of tetanus toxoid vaccine
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6057151 |
Preservation of microorganisms in a vial with a cap comprising an immobilized desiccant
The present invention provides methods and compositions for the safe, effective, and efficient storage and transport of microbial cultures and comprises a vial and cap combination wherein the cap...
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6057145 |
Mass production and long-term preservation of fungivorous nematodes and uses thereof
A host fungus of a fungivorous nematode is inoculated on a solid medium or an artificial liquid medium containing an industrial vegetable waste or by-product, and then the nematode whose whole body...
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6057132 |
Nucleotide sequences encoding apoptosis associated Bbk protein
The present invention is directed to an isolated Bbk protein, nucleotide sequences coding for and regulating expression of the protein, antibodies directed against the protein, and recombinant...
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