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6271034 |
One step allelic exchange in mycobacteria using in vitro generated conditional transducing phages
The present invention provides a method for high frequency of allelic exchange in the slow-growing mycobacteria using in vitro generated specialized transducing mycobacteriophages, as well as the...
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6268203 |
Biological control of purple loosestrife
The present invention provides a novel isolated and purified strain of Sphaeropsis sp. It further provides a mycoherbicidal composition that is effective in controlling purple loosestrife, and...
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6268169 |
Recombinantly produced spider silk
The invention relates to novel spider silk protein analogs derived from the amino acid consensus sequence of repeating units found in the natural spider dragline of Nephila clavipes. More...
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6268127 |
Method for preparing DNA from serum and plasma
Described herein are methods for extracting DNA from serum or plasma, comprising contacting serum or plasma with alkali to yield alkalinized serum or plasma, heating the alkalinized serum or plasma...
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6268177 |
Isolated nucleic acid encoding nucleotide pyrophosphorylase
The invention provides ndp polypeptides and polynucleotides encoding ndp polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing...
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6265203 |
Microorganism culture material containing a water-soluble polymer layer and a porous matrix layer
A culture material is formed containing a water-soluble polymer layer and a porous matrix layer arranged such that when water is applied to the surface of the matrix layer the water diffuses...
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6264952 |
Method for protecting a mammalian host against infection by Brucella
Vaccines against facultative intracellular pathogens are disclosed. A host is vaccinated with non-viable but metabolically active agents. The non-viable agents produce immunogenic components that...
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6265173 |
Methods of modulating the expression of genes using ultraspiracle receptor
In accordance with the present invention, it has been discovered that various members of the steroid/thyroid superfamily of receptors can interact with the insect-derived ultraspiracle receptor, to...
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6265180 |
Nanoemulsions for delivering lipophilic substances into cells
Sterile nanoemulsions are prepared containing oily droplets of a diameter of less than 100 nm in an aqueous phase. The oily droplets contain a lipophilic substance, and have on their surface an...
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6261824 |
Gram negative coccoid bacterium okadaella gastrococcus
A new gram negative coccoid bacterium, Okadaella gastrococcus is disclosed. The bacterium was isolated from an animal with a gastrointestinal disorder.
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6258936 |
SpoIIIE
The invention provides spoIIIE polypeptides and DNA (RNA) encoding spoIIIE polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing...
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6258588 |
Palmaria algal strains and methods for their use
Palmaria cultivars having a growth rate greater than wild type and known strains, particularly when cultured at temperatures greater than about 16° C., and specific embodiments of such cultivars,...
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6255080 |
Bacteriocins produced by ruminal bacteria
Proteinaceous antibiotics produced by ruminal bacteria are provided. The diverse group of ruminal bacteria known as Butyrivibrio spp. is a preferred source of such proteinaceous antibiotics. The...
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6255068 |
Variant gas6 polypeptides
An activator of the Rse receptor protein tyrosine kinase has been identified which is encoded by growth arrest-specific gene 6 (gas6). Accordingly, the present invention provides variant gas6...
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6255100 |
Cyclosporin fermentation process
It has been found that nonimmunosuppressive, cyclophilin-binding cyclosporins are useful in the treatment and prevention of AIDS and AIDS-related disorders. Such cyclosporins include novel...
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6251628 |
Isolated nucleic acid molecules encoding Smad7
The invention describes nucleic acids encoding the Smad7 protein, including fragments and biologically functional variants thereof. Also included are polypeptides and fragments thereof encoded by...
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6251632 |
Canine factor VIII gene, protein and methods of use
The present invention provides isolated nucleic acid molecules encoding canine factor VIII and allelic variants, mutants, fragments or derivatives thereof. The invention also provides canine factor...
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6248541 |
Screening under nutrient limited conditions
Described herein are methods for obtaining from an initial population of cells a plurality of subpopulations of cells having a similar density by growing samples from the initial population in...
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6248525 |
Method for identifying essential or functional genes
Two methodologies are provided: the first provides a means for rapidly and efficiently identifying essential and functional genes; and the second provides a means for obtaining biologically active...
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6248561 |
UCP3 genes
The invention provides methods and compositions relating to a novel family of UCP3 polypeptides and related nucleic acids involved in metabolic regulation. The polypeptides may be produced...
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6245527 |
Nucleic acid molecules encoding glycoprotein VI and recombinant uses thereof
The invention provides isolated TANGO 268 nucleic acid molecules and polypeptide molecules. TANGO 268 encodes a polypeptide that represents glycoprotein VI, a platelet membrane glycoprotein that is...
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6245562 |
Identification of genes altered in multiple myeloma
This invention provides a method of determining a chromosomal breakpoint in a subject suffering from multiple myeloma which comprises steps of: (a) obtaining a DNA sample from the subject suffering...
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6242189 |
Selective isolation of bacterial mRNA
The invention provides methods and compositions for selectively isolating total bacterial mRNA. The general method comprises contacting a bacterial lysate comprising total bacterial mRNA and...
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6242185 |
Purified nucleic acid encoding transcription factor regulatory protein
The invention provides a mammalian nucleic acid sequence and fragments thereof. It also provides for the use of these nucleic acid sequences in a model system for the characterization, diagnosis,...
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6242212 |
Fragile histidine triad (FHIT) nucleic acids and methods of producing FHIT proteins
The present invention relates to nucleotide sequences of FHIT genes and amino acid sequences of their encoded proteins, as well as derivatives and analogs thereof, and antibodies thereto. The FHIT...
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6238918 |
DNA sequence encoding the tumor suppressor gene ING1
The invention provides novel tumor suppressor genes, methods for making and using these and related tumor suppressor genes and proteins and peptides, and nucleic acids encoding these and related...
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6235517 |
Phytase-producing bacteria, phytase and production method of phytase
This invention relates to the isolation of thermophilic phytase-producing microorganisms, method for producing phytase using such microorganisms, phytase obtained therefrom, and usage of the...
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6231857 |
Antibodies to S. mutans and uses thereof
The invention describes three monoclonal IgG antibodies, referred to as SWLA1, SWLA2, and SWLA3, which appear to recognize a species-specific lipooligosaccharide or lipopolysaccharide on the cell...
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6225104 |
Strains of bacteria and pharmaceutical composition containing one or more of such strains and use of same for preventing and treating diseases associated with or caused by altered metabolism of bile acids
Strains of bacteria characterized by exhibiting: (a) a 7α-dehydroxylase activity of less than 50%, and (b) a bile acid deconjugation activity of less than 50%, and descendants, mutants and...
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6221633 |
Insulin derivatives having a rapid onset of action
The present invention relates to insulin derivatives which in comparison to human insulin, have an accelerated onset of action, to a process for their preparation and to their use, in particular in...
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6218147 |
Haemophilus adhesin protein
An adhesin protein which binds specifically to phosphatidylethanolamine (PE), gangliotriaosylceramide (Gg 3 ) and gangliotetraosylceramide (Gg 4 ) has been isolated and purified from H. influenzae....
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6214601 |
Method for inhibiting the growth of microorganisms in an aqueous medium
A method for inhibiting the growth of microorganisms in an aqueous medium comprises contacting the aqueous medium with a permeable body comprising material which interacts with the microorganisms....
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6210927 |
Polynucleotides encoding sbGnRH, a novel reproductive hormone
Novel peptide hormones which influence the release of gonadotropins by the pituitary gland in fish are disclosed. Methods in which such peptides may be administered to fish to control their...
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6210678 |
Reduction of pathogenic bacteria in food products
A composition is provided for reducing bacterial growth in food products. The composition includes a wood extract containing polyphenols and may contain arabinogalactan. The composition suppresses...
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6207440 |
Bacterial nitrite oxidizer
The present invention provides an isolated bacterial strain capable of oxidizing nitrite to nitrate and a method of use thereof for preventing or alleviating the accumulation of nitrite in an...
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6204020 |
DNA encoding N∇2 CSF-1 (short form) and carboxy truncated fragment thereof
A colony stimulating factor, CSF-1, is a lymphokine useful in regulating the immune system, is a lymphokine useful in overcoming the immunosuppression induced by chemotherapy or resulting from...
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6204003 |
Methods for the diagnosis of feline infectious anemia
The claimed invention is a method for determining whether a mammal is infected with Haemobartonella felis or for inducing an immune response against Haemobartonella felis using a polypeptide...
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6204056 |
Micropathological patient replica based on unadulterated whole blood
A patient replica is created from layered culture medium where solid culture medium is formed so that a discontinuity exists, for example, between layers of culture medium or between culture medium...
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6204252 |
Characterization of granulocytic ehrlichia and methods of use
The present invention relates, in general, to granulocytic ehrlichia (GE) proteins. In particular, the present invention relates to nucleic acid molecules coding for GE S2, S7, S22, S23, C6.1,...
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6203799 |
Vibrio cholerae mutants which are soft-agar penetration defective and lack a functional CtxA subunit
V. cholerae vaccine strains which have a soft agar penetration-defective phenotype and methods for making such strains are described. Also described are methods for identifying new genes involved...
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6204057 |
Polynucleotides and the proteins encoded thereby, suitable for controlling lamellicorn beetles
The invention relates to isolated polynucleotides and the proteins encoded thereby, and to their use in controlling lamellicorn beetles (Scarabaeidae). In addition, the invention relates to a...
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6197558 |
Transaminase biotransformation process
A process for making natural and unnatural amino acids which comprises reacting a first amino acid, a keto acid and a transaminase enzyme under conditions appropriate to produce a second amino acid...
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6197579 |
Cell washing device and method
Disclosed is a cell washing device and method of washing cells that utilizes the device. The device is particularly designed for sterile transfer of cells from a primary centrifuge tube and for...
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6194171 |
Nucleic acids encoding ataxin-2 binding proteins
In accordance with the present invention, there are provided novel isolated nucleic acids encoding ataxin-2-binding proteins (A2BPs), functional fragments thereof, vectors containing invention...
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6187555 |
Spores with increased sensitivity to sterilants using additives that bind to sterilant-sensitive sites
Microbial spores having increased sensitivity to sterilants are provided. An additive such as a dipeptide, oligosaccharide, and/or polyhydroxyalcohols are added to the spores wherein the additive...
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6180111 |
Vaccine delivery system
The invention relates to a hyperblebbing strain of Neisseria gonorrhoeae which produces large amounts of blebs useful for production of blebosomes containing antigens for use as a vaccine delivery...
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6177084 |
S. aureusfibrinogen binding protein
The isolation of the S. aureus fibrinogen binding protein gene is described and a minimal fibrinogen binding protein is identified. The protein finds use as a vaccine or a pharmaceutical...
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6174717 |
Elicitor of the hypersensitive response in plants
The nucleic acid and amino acid sequences for proteinaceous elicitors of the plant defense reaction known as the hypersensitive response are described along with methods for preparation and...
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6173527 |
Method for treatment of top soil of a field with ozone gas to increase growth of plants
An ozone containing gas is injected into a portion of top soil that was previously oversaturated with water, to stimulate the propagation and growth of living organisms. The injected ozone oxidizes...
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6171805 |
DNA and host cells encoding a cell surface protein of Porphyromonas gingivalis
A DNA encoding a cell surface polypeptide of Porphyromonas gingivalis, and a recombinant DNA being a DNA having integrated said DNA thereinto. The cell surface polypeptide of the periodontopathic...
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