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7494799 |
Paramunity inducers based on attenuated rabbit myxoma virus
The invention relates to monoparamunity inducers that are based on paramunizing viruses or viral components of a myxoma virus strain of diseased rabbits that show general symptoms of the disease....
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7465580 |
Non-cytotoxic oriP replicon
The invention provides a vector encoding a derivative of EBNA-1 that is not cytotoxic when expressed efficiently in cells, which supports extrachromosomal replication, maintenance and transcription...
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7344723 |
Self-replicating RNA molecule from hepatitis C virus
A unique HCV RNA molecule is provided having an enhanced efficiency of establishing cell culture replication. Novel adaptive mutations have been identified within the HCV non-structural region that...
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7309493 |
Inactivated bovine scours vaccines, process and method of preventing bovine scours
Inactivated scours vaccines for immunization and protection of bovine animals from disease caused by infection with bovine rotavirus and bovine coronavirus, which comprise and effective amount of...
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7235393 |
Method for direct rescue and amplification of integrated viruses from cellular DNA of tissues
A method for isolating AAV viruses from cellular DNA of non-human primate (NHP) tissues by transfecting the DNA of NHP into 293 cells, rescuing the virus and amplifying it through serial passages...
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RE39494 |
Inactivated mycoplasma hyopneumoniae and uses therefor
The invention relates to a method for making an inactivated vaccine of Mycoplasma hyopneumoniae by inactivating the bacteria with Thimerosal. The resulting bacterin is mixed with an adjuvant of...
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7150984 |
Attenuated human rotavirus vaccine
The present invention provides vaccine compositions of attenuated human rotavirus. More particularly, the attenuated human rotavirus is produced by cold passage and thus contains attenuating...
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7037508 |
Pestivirus mutants and vaccines containing the same
The present invention is directed to attenuated pestivirus mutants, which have a reduced ability to replicate as exhibited by a small plaque size. The mutations are in the 5′ nontranslated region...
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7029682 |
Inactivated vaccine against feline calicivirosis
Immunogenic preparations and vaccines, in particular which are inactivated, effective against feline calicivirosis, based on an FCV virus strain 431 as deposited at the CNCM under the accession...
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6982160 |
Immunogenic compositions that include SIRS virus
The invention includes kits for producing and using immunogenic compositions that include swine infertility and respiratory virus. The invention also includes vaccines and sera for treatment of...
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6974577 |
Inactivated bovine scours vaccines, processes and method of preventing bovine scours
Inactivated scours vaccines for immunization and protection of bovine animals from disease caused by infection with bovine rotavirus and bovine coronavirus, which comprise and effective amount of...
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6946136 |
Temperature-sensitive and cold-adapted human parainfluenza virus type 2 (HPIV-2) and vaccines based on such virus
The present invention relates to isolated, attenuated viral strains of human parainfluenza virus 2 (HPIV-2), which are useful in live vaccine preparations. These strains exhibit a temperature...
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6682743 |
Altered strain of the modified vaccinia virus ankara (MVA)
The invention provides new strains of the Modified Vaccinia Virus Ankara (MVA) that have a strongly reduced virulence for most mammals, especially humans, but nevertheless grows in cells of a...
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6660272 |
Porcine circoviruses, vaccines and diagnostic reagents
The invention relates to new porcine circovirus strains isolated from pulmonary or ganglionic samples obtained from farms affected by the post-weaning multisystemic wasting syndrome (PMWS). It...
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6632647 |
Use of strains of parapoxvirus ovis against organ fibrosis
The present invention relates to the use, in humans, of inactivated parapoxviruses for the prophylaxis and treatment of diseases which are accompanied by an increased deposition of collagen, with...
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6605460 |
Avian pneumovirus vaccine
Compositions and methods for ameliorating the clinical signs of an avian pneumovirus infection in a bird are disclosed. The compositions include immunologically effective amounts of an attenuated...
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6511667 |
Attenuated dengue-2 virus vaccine
The present invention provides vaccine compositions of attenuated dengue-2 virus. More specifically, the attenuated virus is produced by serial passage in PDK cells. The invention also provides...
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6423318 |
Hepatitis A virus vaccines
A live hepatitis A virus adapted to growth in MRC-5 cells, which HAV is preferably characterized by suitable attenuation for effective vaccine administration to humans and animals without...
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6416764 |
Vaccine
A vaccine comprises a non-cytopathogenic strain of bovine viral diarrhea virus, grown in a bovine derived cell line such as MDBK and killed, for example with β-propiolactone. The adjuvant is Quil A.
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6410297 |
Processes for preparation of Marek's disease virus using continuous avian cell lines
The present invention relates to avian cell lines which efficiently support the growth and productive infection of Marek's Disease Virus at high titers. The present invention also relates to avian...
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6309650 |
Attenuated Japanese encephalitis virus adapted to Vero cell and a Japanese encephalitis vaccine
An attenuated Japanese encephalitis virus adapted to Vero cell by passages on Vero cell is disclosed. A Japanese encephalitis vaccine comprising said attenuated virus is also disclosed.
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RE37381 |
Vaccine against hepatitis A virus
The present invention provides an attenuated hepatitis A virus useful as a vaccine.
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6284254 |
Immunogenic compositions comprising cold-adapted attenuated respiratory syncytial virus mutants
The respiratory syncytial virus (RSV) is a major cause of lower respiratory tract disease in infants and children throughout the world. RSV is a major cause of pneumonia and bronchiolitis in...
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6270770 |
Chicken anaemia agent broiler vaccine
The present invention for the first time discloses a health problem in broilers at about 3-5 weeks, resulting in significant production losses, and demonstrates that these production losses can be...
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6251654 |
Modified small RNA viruses
Small RNA viruses and virus-like particles (VLPs) have altered or substituted Ig-like domains so as to modify host cell tropism. The invention also relates to the use of such small RNA viruses and...
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6241990 |
Immunogenic composition containing inactivated swine infertility and respiratory Syndrome virus
The invention includes a vaccine and sera for treatment of Mystery Swine Disease (MSD), a method for producing the vaccine, methods for diagnosis of MSD, a viral agent that will mimic "mystery...
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6210683 |
Stabilizers containing recombinant human serum albumin for live virus vaccines
Compositions are provided for improving the stability of live virus vaccines containing, e.g., live varicella zoster, measles, mumps, and rubella viruses. Such improved stabilizers are aqueous...
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6180110 |
Attenuated hepatitis a virus vaccine which grows in MRC-5 cells
A live hepatitis A virus (HAV) adapted to grow in MRC-5 cells is described, the HAV preferably characterized by suitable attenuation for effective vaccine administration to humans and animals...
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6168916 |
Host adaptation of retroviral vectors
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6146873 |
Production of orthomyxoviruses in monkey kidney cells using protein-free media
Viruses from the family Orthomyxoviridae, particularly influenza virus, can grown in monkey kidney cells, particularly Vero Cells, after passaging the cells in a serum-free or protein-free medium....
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6146643 |
Human/simian chimeric hepatitis A virus vaccine
The present invention relates, in general, to a substantially pure preparation of the simian hepatitis A viral isolate AGM-27; a substantially pure preparation of the genomic DNA of simian...
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6136322 |
Hepatitis A virus deletion mutants and vaccine formulations containing the same
Disclosed are live hepatitis A virus deletion mutants having a deletion mutation in the 5' nontranslated region of the viral genome. The deletion mutation may be selected from the group consisting...
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6129920 |
Inactivated infectious bursal disease vaccine
The present invention is concerned with Infectious bursitis virus (IBDV) vaccines containing IBDV antigen material which is derived from a mammalian cell line infected with IBDV.
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6110467 |
Isolated porcine respiratory and reproductive virus, vaccines and methods of protecting a pig against a disease caused by a porcine respiratory and reproductive virus
The present invention provides a vaccine which protects pigs from a virus and/or an infectious agent causing a porcine respiratory and reproductive disease, a method of protecting a pig from a...
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6110468 |
Vaccine for swine infertility and respiratory syndrome and method of use thereof
The invention includes a vaccine and sera for treatment of Mystery Swine Disease (MSD), a method for producing the vaccine, methods for diagnosis of MSD, a viral agent that will mimic "mystery...
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6086892 |
Poultry vaccine
This invention relates to a novel infectious bronchitis virus (IBV) serotype and to attenuated IBV strains derived therefrom, and also to live or inactivated vaccines made using such IB virus. This...
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6080570 |
Method of producing a vaccine for Swine Infertility and Respiratory Syndrome
The invention includes a vaccine and sera for treatment of Mystery Swine Disease (MSD), a method for producing the vaccine, methods for diagnosis of MSD, a viral agent that will mimic "mystery...
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6066489 |
Method for treating blood borne viral pathogens such as immunodeficiency virus
A method and apparatus for destroying blood borne pathogens is disclosed which utilizes a low intensity direct current to generate positive particles from various metals which destroy viral...
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6042843 |
Baculovirus for the control of insect pests
A novel Plutella xylostella baculovirus (PxMNPV) which is useful for the control of insect pests has been isolated. A variety of insect pests may be controlled by application of an insecticidally...
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6042830 |
Viral agent associated with mystery swine disease
A substantially avirulent vaccine against Porcine Reproductive and Respiratory Syndrome (PRRS) is provided, which effectively immunizes swine against the U.S. and European forms of the disease,...
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6017542 |
Nucleotide and amino acid sequences of canine herpesvirus GD and uses therefor
Disclosed and claimed are nucleotides for genes encoding the canine herpesvirus (CHV) gB, gC and gD homologues. These genes encode polypeptides of 879, 459 and 345 amino acids, respectively, which...
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6010894 |
Method of screening for attenuating viruses
The present invention provides a method of selecting virus vaccine candidates by selecting virus variants that do not bind to brain membrane receptor preparations, comprising the steps of: (a)...
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6001370 |
Attenuated strain of the virus causing the porcine reproductive respiratory syndrome (PRRS), and vaccines
A new attenuated strain (CNCM Institut Pasteur I-1642) of the virus causing the swine disease known as porcine reproductive and respiratory syndrome (PRRS) is described, along with an attenuation...
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5993822 |
Modified live avian polymavirus vaccine in psittacine birds
The present invention provides a vaccine which is protective against avian polyomavirus infection in a bird which is classified as being a member of the Psittaciformes order which comprises an...
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5994116 |
Herpesvirus pre-(viral DNA replication) enveloped particles
This invention is directed toward a new type of herpesvirus particle (e.g., HSV-1), herein designated pre-viral DNA replication enveloped particles (PREPS), and methods of preparing said particles....
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5968525 |
Inactivated Mycolplasma hyopneumoniae and uses therefor
The invention relates to a method for making an inactivated vaccine of Mycoplasma hyopneumoniae by inactivating the bacteria with Thimerosal. The resulting bacterin is mixed with an adjuvant of...
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5932222 |
Mutant respiratory syncytial virus (RSV), vaccines containing same and methods of use
This invention provides cold adapted mutant RSV, specifically, mutant RSV of subgroup A and B. Nucleic acid molecules encoding the mutant RSV of this invention, and immunogenic polypeptides of...
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5925359 |
European vaccine strains of the porcine reproductive and respiratory syndrome virus
The present invention is concerned with European strains of the Porcine Reproductive Respiratory Syndrome (PRRS) virus, having as a unique feature that they are non-infectious to macrophages, and...
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5922326 |
Attenuated respiratory syncytial virus vaccine compositions
The present invention provides vaccine compositions of attenuated respiratory syncytial virus (RSV). More particularly, the attenuated virus may be a derivative of RSV which has been incompletely...
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5919461 |
Nonpathogenic infectious bursal disease virus and vaccine
An Infectious Bursal Disease Virus of the Delaware Variant E type having the characteristics of being able to grow on both VERO cells and CEF cells, reacting with monoclonal antibody BK9 produced...
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