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7405066 |
Bacteriophage and their uses
There is provided a bacteriophage capable of lysing a P. acnes bacterium and incapable of lysing a bacterium which is not P. acnes , and which is incapable of sustaining lysogeny in a bacterium....
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7402392 |
In vivo panning for ligands to radiation-induced molecules
A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. The method includes the steps of: (a) exposing a tumor to ionizing radiation; (b)...
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7393527 |
Method for limiting the growth of cancer cells using an attenuated measles virus
A method for treating cancer cells is provided comprising directly or systemically administering a therapeutically effective dose of an attenuated measles virus. In one embodiment, the...
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7393677 |
Avidin-pseudotyped viral vectors and their use
The present invention pertains to an avidin-pseudotyped virus, and especially baculovirus, useful for delivery of foreign genes etc. The present invention also pertains to vectors comprising...
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7390495 |
Neurovirulent strain of the West Nile virus and uses thereof
Neuroinvasive and neurovirulent strain of the West Nile virus, named IS-98-ST1, nucleic acid molecules derived from its genome, proteins and peptides encoded by said nucleic acid molecules, and...
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7384774 |
Helper-free rescue of recombinant negative strand RNA virus
The present invention relates methods of generating infectious negative-strand virus in host cells by an entirely vector-based system without the aid of a helper virus. In particular, the present...
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7384643 |
Recombinant poxvirus
Use for novel chemokine-binding protein designated A41L, and chemokine-binding fragments thereof, for the treatment of conditions such as inflammation. The A41L protein binds to chemokines in the...
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7374752 |
Reovirus for the treatment of cellular proliferative disorders
Methods for treating proliferative disorders, by administering reovirus to a Ras-mediated proliferative disorder, are disclosed. The reovirus is administered so that it ultimately directly contacts...
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7374768 |
Viral vaccines
A mutant virus for use as a vaccine for prophylaxis or therapy, wherein the genome of the virus is defective in respect of a gene essential for the production of infectious virus. In one aspect the...
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7374875 |
Peptides having affinity for the gp120 viral protein and use thereof
The present invention relates to a family of peptides exhibiting high affinity and specificity for the viral protein gp120, to methods for producing these peptides, and to the use of these peptides.
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7375204 |
Fungal cell wall synthesis gene
A reporter system reflecting the transport process that transports GPI-anchored proteins to the cell wall was constructed and compounds inhibiting this process were discovered. Further, fungal...
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7371846 |
CD4-independent HIV envelope proteins as vaccines and therapeutics
The invention relates to novel CD4-independent HIV Envelope proteins and uses therefor.
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7371542 |
Gene expression system
The present invention relates to nucleic acid molecules and in particular to vectors, comprising at least one gene of interest, at least one scaffold/matrix attached region (S/MAR), at least one...
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7371841 |
Methods of modulating cold sensory perception
The present invention relates to regulation of cold sensation and pain. More particularly, the present invention is directed to nucleic acids encoding a member of the transient regulatory protein...
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7371836 |
PRO526 nucleic acids
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host ceolls comprising those nucleic acid...
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7364876 |
ADIP protein and use thereof
The objective of the present invention is to provide a gene encoding novel afadin DIL domain-binding protein (ADIP) and use of the novel ADIP protein. The present inventors successfully identified...
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7361502 |
Nucleic acid molecule encoding a neuronal serine-threonine protein kinase
The present invention relates to a gene and the coded protein thereof that is involved in the development of sequelae of local ischaemia. The new protein is a serine threonine protein kinase and...
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7361496 |
Rescue of mumps virus from cDNA
This invention relates to a method for recombinantly producing, via rescue of mumps virus, a nonsegmented, negative-sense, single-stranded RNA virus, and immunogenic compositions formed therefrom....
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RE40233 |
Viral variants and methods for detecting same
The present invention relates generally to viral variants exhibiting reduced sensitivity to particular agents and/or reduced interactivity with immunological reagents. More particularly, the...
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7354993 |
Insecticidal polypeptides and methods of use thereof
The invention relates to isolated insecticidal polypeptides expressed in the venom gland of spiders of the genera Atrax and Hadronyche have been described. Methods of treating insects, insect...
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7355033 |
Screening for West Nile Virus antiviral therapy
The instant invention provides stable and novel lineage I WNV reverse genetics systems, and methods for making the reverse genetics systems, specifically, a fully-infectious lineage I WNV cDNA or...
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7351533 |
In vitro method for disassmbly/reassembly of papillomavirus virus-like particles (VLPs). Homogeneous VLP and cavsomere compositions produced by said methods: use thereof as vehicle for improved purification, and delivery of active agents
A method of disassembly/reassembly of papillomavinis VLPs is provided. The resultant VLPs have enhanced homogeneity, present conformational, neutralizing PV epitopes, and therefore are useful...
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7351579 |
***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***
Circovirus sequences associated with piglet weight loss disease (PWD)
The genome sequences and the nucleotide sequences coding for the PWD circovirus polypeptides, such as the circovirus structural and non-structural polypeptides, vectors including the sequences, and...
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7351570 |
HDV nucleic acid molecules and applications thereof
The invention concerns nucleic acid molecules derived from novel hepatitis D virus strains or isolates constituting genotypes different from known I, II and III genotypes, their fragments,...
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7348014 |
Poxvirus with targeted infection specificity
The present invention concerns a poxviral particle having a targeted infection specificity conferred by an heterologous ligand moiety present at the surface of said poxviral particle and capable of...
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7344830 |
Heteroduplex tracking assay
A change in viral tropism occurs in many HIV positive individuals over time and may be indicated by a shift in coreceptor use from CCR5 to CXCR4. The shift in coreceptor use to CXCR4 has been shown...
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7344873 |
Methods of adenovirus production
A simple yet effective method of increasing production of a thermo-stable virus, such as adenovirus and picornavirus, is presented. The method entails a temperature shift strategy whereby the...
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7344839 |
Virus preparations and methods
Methods are disclosed for the preparation of herpesvirus, such as herpes simplex virus type 2 for vaccine use. Such viruses can be grown on serum free or serum containing media and can be prepared...
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7344723 |
Self-replicating RNA molecule from hepatitis C virus
A unique HCV RNA molecule is provided having an enhanced efficiency of establishing cell culture replication. Novel adaptive mutations have been identified within the HCV non-structural region that...
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7344872 |
Method for rapid screening of bacterial transformants and novel simian adenovirus proteins
Chimpanzee serotype C68 proteins, peptides, and polypeptide are provided. Also provided are novel adenoviruses derived from these proteins, as well as compositions containing these proteins and...
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7339046 |
CFTR with a partially deleted R domain and uses thereof
The present invention offers new therapies for treating Cystic Fibrosis (CF), that are based on novel DNA molecules and proteins encoded by the DNA molecules. The present invention features DNA...
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7338662 |
Recombinant poxvirus expressing homologous genes inserted into the foxviral genome
The sent invention relates to a recombinant poxvirus vector capable of expressing two or more homologous, foreign sequences, which derive from different variants of a microorganism, and which have...
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7338759 |
HCV variants
HCV variants are described. The variants include polynucleotides comprising non-naturally occurring HCV sequences and HCV variants that have a transfection efficiency and ability to survive...
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7338661 |
Infectious bursal disease virus antigenic isolates and vaccines
Antigenic isolates and vaccines for Infectious Bursal Disease Virus include variants of the molecular Group 6 family of IBDV isolates, in particular the 28-1 isolate.
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7338799 |
Polynucleotide encoding a mouse choline transporter
Human high affinity choline transporter (CHT) cDNA was cloned from spinal cord and the primary structure and chromosomal localization have been determined. Mouse high affinity CHT cDNA was also...
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7335364 |
Modified Vaccinia Ankara virus variant
The present invention provides an attenuated virus, which is derived from Modified Vaccinia Ankara virus and characterized by the loss of its capability to reproductively replicate in human cell...
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7332321 |
Viral fibers
Long rod shaped M13 viruses were used to fabricate one dimensional (1D) micro- and nanosized diameter fibers by mimic the spinning process of the silk spider. Liquid crystalline virus suspensions...
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7329530 |
Chimaeric phages
The invention relates to the field of generating helper phages and phage display libraries for the identification of binding molecules. The invention provide chimaeric phages having a coat...
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7329725 |
Phage displayed Trp cage ligands
Trp cage binding domain polypeptides are disclosed. The Trp cage binding domains have the generic formulas of SEQ ID NO: 2, 7, 10 or 11. They can be efficiently produced and screened using phage...
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7323177 |
Recombinant porcine adenovirus vector
This invention relates to a recombinant vector including a recombinant porcine adenovirus, stably incorporating and capable of expression of at least one heterologous nucleotide sequence. The...
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7323623 |
RHIZOC3 nucleic acid molecules
The present invention is directed to nucleic acid molecules tat encode defensive polypeptides and methods of their use in enhancing disease resistance of a plant to a fungal pathogen. Vectors,...
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7320888 |
Submergence-induced protein-like factors
A pure polypeptide containing an amino acid sequence at least 80% identical to SEQ ID NO:5. The polypeptide, when expressed in a cell, increases susceptibility of the cell to hepatitis C virus...
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7316898 |
Method of determining adenovirus particle concentration
The invention discloses a simple, accurate and reproducible method of determining viral particle concentration, especially for any serotype of adenovirus. More specifically, an accurate...
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7317142 |
Immunization of fish with plant-expressed recombinant proteins
Plants are produced that express an amino acid sequence that, when administered to a fish, produce an antigenic or immune response in the fish. The amino acid sequence in one embodiment is an...
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7314754 |
Polynucleotide encoding the hOT7T175 G protein coupled receptor
The present invention relates to a polynucleotide encoding a human brain-derived G protein coupled receptor protein. The human brain-derived G protein coupled receptor protein is useful: (1) for...
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7314716 |
Gustducin γ subunit materials and methods
Gustducin is a taste receptor cell heterotrimeric guanine nucleotide binding protein. Disclosed herein is the amino acid sequence of the gamma (γ) subunit of gustducin, as well as polynucleotide...
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7314631 |
Use of recombinant live-attenuated parainfluenza virus (PIV) as a vector to protect against disease caused by PIV and respiratory syncytial virus (RSV)
Chimeric parainfluenza viruses (PIVs) are provided that incorporate a PIV vector genome or antigenome and one or more antigenic determinant(s) of a heterologous PIV or non-PIV pathogen. These...
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7313357 |
Method for typing and detecting HBV
The present invention relates to a method for detection and/or genetic analysis of HBV in a biological sample, comprising hybridizing the polynucleic acids of the sample with a combination of at...
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7312030 |
Adaptation sites of porcine reproductive and respiratory syndrome virus
A method for determining the capability of an arterivirus to replicate in a permissive cell is disclosed. The method includes determining an amino acid at a position that corresponds to an amino...
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7309495 |
Hemorrhagic feline calicivirus
The present invention relates to a vaccine for immunization against a viral infection caused by a hemorrhagic feline calicivirus (hFCV), a novel, a typical and unusually virulent form of a...
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