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8183025 Solenopsis invicta virus  
A Unique Solenopsis invicta viruse (SINV2) have been identified and its genome sequenced. Oligonucleotide primers have been developed using the isolated nucleic acid sequences of the SINV2. The...
8173136 Attenuated recombinant newcastle disease virus and vaccine containing the same  
The present invention relates to a recombinant vector for transcription of the Newcastle disease virus (NDV) genome, a strain of attenuated recombinant NDV with a surface antigen of pathogenic NDV...
8168418 Expression of HIV polypeptides and production of virus-like particles  
The present invention relates to the efficient expression of HIV polypeptides in a variety of cell types, including, but not limited to, mammalian, insect, and plant cells. Synthetic expression...
8168200 Vaccine against african horse sickness virus  
The present invention provides vectors that contain and express in vivo the genes encoding VP2 and VP5 of African Horse Sickness Virus or an epitope thereof that elicits an immune response in a...
8168419 Prevention and remediation of petroleum reservoir souring and corrosion by treatment with virulent bacteriophage  
Petroleum reservoir souring, caused by microbially induced production of hydrogen sulfide and other sulfur compounds, and the attendant corrosion are remediated by isolating bacteriophage(s)...
8163543 AAV vectors produced in insect cells  
The present invention relates to the production of adeno-associated viral vectors in insect cells. The insect cells therefore comprise a first nucleotide sequence encoding the adeno-associated...
8163530 Nucleic acids encoding respiratory syncytial virus subgroup B strain 9320  
The complete polynucleotide sequence of the human respiratory syncytial virus subgroup B strain 9320 genome is provided. Proteins encoded by this polynucleotide sequence are also provided. Isolated...
8158418 Chimeric alphavirus replicon particles  
Chimeric alphaviruses and alphavirus replicon particles are provided, including methods of making and using same. Specifically, alphavirus particles are provided having nucleic acid molecules...
8158411 Method of separating microorganism using nonplanar solid substrate and device for separating microorganism using the same  
Provided is a method of separating microorganisms from a sample including contacting the sample containing microorganisms with an inorganic ion exchange material such that the sample reacts with...
8148129 Generation of potent dominant negative transcriptional inhibitors  
The present invention provides methods and compositions for regulating gene expression using transcription factors linked to proteins that localize to the transcriptional machinery.
8148131 Bacteriophage and antibacterial composition comprising the same  
The present invention relates to a novel bacteriophage, more particularly, a bacteriophage that has a specific bactericidal activity against Fowl Typhoid causing Salmonella Gallinarum (SG) and...
8148130 T4 bacteriophage bound to a substrate  
T4 bacteriophages are bound to substrates such as liposomes using a binder.
8142796 Monoparamunity inducers based on attenuated rabbit myxomaviruses  
The present invention relates to monoparamunity inducers based on paramunizing viruses or viral components of a myxomavirus strain from rabbits with typically generalizing disease, to a method for...
8143022 High production system for infectious hepatitis C virus particle  
The present invention relates to a method for producing infectious hepatitis C virus (HCV) particles, comprising a step of introducing an expression vector into a cell that allows HCV...
8142795 Stabilizer and vaccine composition comprising one or more live attenuated flaviviruses  
The present invention relates to stabilizers for compositions, including immunogenic compositions, such as vaccine compositions, comprising one or more live attenuated flaviviruses, to bulk vaccine...
8143213 Effect of TULA on HIV  
A method of inhibiting a retrovirus production, the method includes administering a retrovirus inhibitor selected from at least one of a TULA protein, a fragment of TULA containing a UBA domain, a...
8137947 Viral vectors whose replication and, optionally, passenger gene are controlled by a gene switch activated by heat in the presence or absence of a small-molecule regulator  
The present invention relates to conditionally replicating viruses or pairs of viruses containing a gene switch that is activatable by transient heat or other proteotoxic stress in the presence or...
8138390 Biological control agent for plants  
A biological control agent for plants and a method of inoculating the plants with the biological control agent in order protect against plant disease are provided. The treatment method consists of...
8133712 Inactivated chimeric vaccines and related methods of use  
Embodiments of the present invention provide an inactivated chimeric virus and immunogenic compositions for the treatment or prevention of infection with West Nile virus. Further, other embodiments...
8133498 Use of polynucleotides encoding small acid-soluble spore protein for inhibiting bacterial cell growth and/or treating bacterial infections  
A polypeptide having α/β type SASP activity, for use as a medicament.
8128937 N protein mutants of porcine reproductive and respiratory syndrome virus  
The present invention provides a genetically modified PRRS virus, methods to make it and related polypeptides, polynucleotides and various components. Vaccines comprising the genetically modified...
8129598 DNA recombination in eukaryotic cells by the bacteriophage PHIC31 recombination system  
This invention provides methods for obtaining specific and stable integration of nucleic acids into eukaryotic cells. The invention makes use of site-specific recombination systems that use...
8124397 Inactivating pathogens with oxidizing agents for vaccine production  
The present disclosure provides methods for producing a vaccine composition containing a pathogen that is rendered noninfectious by exposure to hydrogen peroxide. The methods disclosed herein are...
8124398 Recombinant flavivirus vaccines  
The invention provides recombinant flavivirus vaccines that can be used in the prevention and treatment of flavivirus infection. The vaccines of the invention contain recombinant flaviviruses...
8124355 Detection and identification of groups of bacteria  
The present invention concerns a method for the simultaneous detection of different bacteria, comprising the following steps: coupling one or more species of bacteriophage tail proteins onto a...
8124032 Microfluidic device and method of using same  
The invention relates to a microfluidic device comprising one or more fluid channels, one or more fluid ports, and a V-shaped particle retention structure. The fluid channel is generally opposite...
8124407 Circular nucleic acid vectors, and methods for making and using the same  
Circular nucleic acid vectors that provide for persistently high levels of protein expression are provided. The circular vectors of the subject invention are characterized by being devoid of...
8124409 Utilizing liver cell line QSG-7701 to be infected with hepatitis B virus  
The use of the liver cell line QSG-7701 for HBV infection includes the following steps: directly infecting QSG-7701 cells with purified HBV particles and facilitating the infection by DMSO and/or...
8119337 Decreasing potential iatrogenic risks associated with influenza vaccines  
Influenza viruses for use in preparing human vaccines have traditionally been grown on embryonated hen eggs, although more modern techniques grow the virus in mammalian cell culture e.g. on Vero,...
8119366 Antennapedia-dominant negative mastermind-like construct  
The present invention is based on the discovery that the Notch signaling pathway is associated with cancer. Accordingly, the invention provides methods and compositions for treating cancer. Also...
8114637 Packaging cells for recombinant adenovirus  
In the absence of substantial sequence overlap between a recombinant adenoviral vector and the genome of a packaging cell, helper-dependent E1-containing particles (HDEP) can be formed at low...
8110390 PRRS viruses, infectious clones, mutants thereof, and methods of use  
The present invention provides isolated infectious polynucleotides, such as infectious clones, having a nucleotide sequence with identity to PRRS viruses such as VR-2332, Lelystad, or others, and...
8105767 Cells for detection of enteroviruses  
The invention provides cell lines which are useful for the rapid detection of enteroviruses. In particular, the invention provides transgenic African green monkey kidney cell lines and buffalo...
8105578 Treatment of neoplasms with viruses  
The subject invention relates to viruses that are able to replicate and thereby kill neoplastic cells with a deficiency in the IFN-mediated antiviral response, and their use in treating neoplastic...
8101412 Method of enhancing proliferation and/or hematopoietic differentiation of stem cells  
The present invention provides a method for enhancing the proliferation and/or hematopoietic differentiation and/or maintenance of mammalian stem cells. The method is useful for generating expanded...
8101172 Solenopsis invicta virus  
A Unique Solenopsis invicta virus (SINV 3) has been identified and its genome sequenced. Oligonucleotide primers have been developed using the isolated nucleic acid sequences of the SINV 3. The...
8093033 Multi plasmid system for the production of influenza virus  
Vectors and methods for the production of influenza viruses suitable as recombinant influenza vaccines in cell culture are provided. Bi-directional expression vectors for use in a multi-plasmid...
8088392 Capsid proteins and uses therefore  
The present invention provides methods for the use of viral capsid proteins and chaperone proteins to produce immunogenic macro-molecular structures as antigen carrier to carry desired epitopes or...
8088393 Swine influenza hemagglutinin variants  
Polypeptides, polynucleotides, methods, compositions, and vaccines comprising influenza hemagglutinin and neuraminidase variants are provided.
8088391 West nile virus vaccine  
The invention provides chimeric flavivirus vaccines against West Nile virus and methods of using these vaccines to prevent or treat West Nile virus infection.
8084229 GDEP enhancer element and use thereof to confer retinal specific gene expression  
The present invention is directed to isolated nucleic acids containing functional polynucleotide sequences representing an enhancer element for the Gene Differentially Expressed in Prostate (GDEP)....
8084228 Nogo-B receptor antagonists  
Nogo-B receptors bind to Nogo-B and mediate its biological function. We have discovered that Nogo-B receptor is a component of endothelial cells, and is highly expressed in intact blood vessels....
8084433 Antisense antiviral compound and method for treating ssRNA viral infection  
The invention provides antisense antiviral compounds and methods of their use and production in inhibition of growth of viruses of the Flaviviridae, Picomoviridae, Caliciviridae, Togaviridae,...
8084039 Methods and compositions for live attenuated viruses  
Embodiments herein relate to compositions of and methods for live viruses. In certain embodiments, a live, attenuated virus composition includes, but is not limited to, one or more live, attenuated...
8075903 Dengue tetravalent vaccine containing a common 30 nucleotide deletion in the 3′-UTR of dengue types 1, 2, 3, and 4 or antigenic chimeric dengue viruses 1, 2, 3, and 4  
The invention relates to a dengue virus tetravalent vaccine containing a common 30 nucleotide deletion (Δ30) in the 3′-untranslated region of the genome of dengue virus serotypes 1, 2, 3, and 4, or...
8071352 Bacteriophage having killing activity specific to Staphylococcus aureus  
The present invention relates to a novel bacteriophage, more precisely a novel bacteriophage having killing activity specific to Staphylococcus aureus which is the causing agent of infectious...
8067236 Optimized human T1R3 nucleic acid molecule  
The present invention relates to a screening system for modulators of GPCRs. Further it relates to recombinant vector systems for the heterologous expression of heterodimeric g-protein coupled...
8067179 Immunoglobulin libraries  
Methods and compositions for the screening and isolation of ligand-binding polypeptides, such as antibodies. In some aspects, methods of the invention enable the isolation of intact soluble...
8067229 UCP4  
The present invention is directed to novel polypeptides having homology to certain human uncoupling proteins (“UCPs”) and to nucleic acid molecules encoding those polypeptides. Also provided her...
8067010 Immunological herpes simplex virus antigens and methods for use thereof  
The invention provides HSV antigens that are useful for the prevention and treatment of HSV infection. Disclosed herein are antigens and/or their constituent epitopes confirmed to be recognized by...