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7588926 |
Proteases
The invention relates to a novel class of serine proteases of peptidase family S2A or S1E that are stable in the presence of copper (Cu2+) and/or inhibited by copper only to a limited extent....
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7404977 |
Rennets
The present invention describes an aspartic protease produced by a fungus from the class Eurotiomycetes, comprising the amino acid sequence of FDTGSSD or FDTGSSE. The present invention further...
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7393667 |
Stereoselective reduction process for the preparation of pyrrolotriazine compounds
The invention relates to a process for the enzymatic, stereoselective reduction of ketone compounds to provide chiral alcohols, for example the compound of formula Ib:
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7368274 |
Expression of recombinant proteinase K from Tritirachium album in yeast
The invention concerns a method for the expression of a gene coding for a soluble proteinase K in yeast e.g. in Pichia pastoris with subsequent secretion into the culture medium. In addition a...
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7368272 |
Expression of proteolytic enzymes in koji mold in the presence of carbon sources
The present invention refers to a koji mold capable of expressing proteolytic enzymes in the presence of a carbon source in at least the same amount as in the absence thereof. In particular, the...
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7262287 |
Hansenula polymorpha yapsin deficient mutant strain and process for the preparation of recombinant proteins using the same
The present invention relates to a nucleic acid molecule comprising the HpYPS1 gene encoding H. polymorpha yapsin1, a polypeptide encoded by the nucleic acid molecule, a H. polymorpha mutant...
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7192754 |
Nomuraeae rileyi-origin ecdysteroid 22-oxidase and molt hormone inactivation system with the use of the same
A material and a system are provided that efficiently inactivate a molting hormone by means of a protein having ecdysteroid 22-oxidase activity.
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7186546 |
Process for the preparation of alkaline protease
The present invention relates to a process for the preparation of alkaline protease using a fungal culture of the order entomophthorales and to the use of the said protease in the pretanning...
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7037673 |
Dipeptide production method, L-amino acid amide hydrolase used therein, and production method of L-amino acid amide hydrolase
A process for industrially advantageously producing a dipeptide via a convenient pathway starting with less expensive and easily available materials is provided. A dipeptide is produced from an...
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6846656 |
Process for producing N-acetylneuraminic acid
The present invention provides a process for economically producing N-acetylneuraminic acid without using expensive materials such as pyruvic acid and phosphoenolpyruvic acid. The process...
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6797273 |
Neisseria meningitidis antigen
The invention provides BASB053 polypeptides and polynucleotides encoding BASB053 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic,...
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6548745 |
Italian rye grass and a method of introducing endophytic fungi into an italian rye grass
To provide an Italian rye grass with excellent characteristics, and in particular, excellent insect resistance and disease resistance, an endophyte, which is a filamentous endophytic fungus living...
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6475485 |
Two novel human cathepsin proteins
The present invention provides two novel human cathepsin proteins (HCPs) and polynucleotides encoding HCPs. The invention provides for genetically engineered expression vectors and host cells...
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6440413 |
Medicament for optimizing mucosal viscosity and stimulating intestinal function
The invention pertains to the field of biology, and more particularly, to therapeutic chemistry, and discloses pharmaceutical compositions containing, as an active ingredient, an enzyme or an...
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6379928 |
Heterologous polypeptides expressed in filamentous fungi, processes for making same, and vectors for making same
Novel vectors are disclosed for expressing and secreting heterologous polypeptides from filamentous fungi. Such vectors are used in novel processes to express and secrete such heterologous...
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6207437 |
Crystalline protease and method for producing same
A method for preparing a crystalline protease is provided which comprises preparing an aqueous solution containing the protease enzyme and adding to the aqueous solution sodium sulfate, allowing...
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6187579 |
Customized proteases
The invention provides customized proteases (i.e., mutant enzymes), methods of making customized proteases, as well as methods of using customized proteases. The customized proteases of the...
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6156557 |
Alkaline protease from streptomyces sp. and method for preparing the same
Disclosed is an alkaline protease having a specific activity of 214,000 (U/mg protein) when using casein as a substrate and 52,700 (U/mg protein) when using keratin as a substrate. The alkaline...
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6127142 |
Microbially derived enzymes having enhanced milk clotting activity and method of producing same
A method of producing a milk clotting enzyme including the steps of (a) fermenting a strain of Rhizomucor miehei or Aspergillus oryzae to form a fermentation product having a glycoslated Rhizomucor...
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6103511 |
Lichenase and coding sequences
The present invention provides a fungal lichenase, i.e., an endo-1,3-1,4-β-D-glucanohydrolase, its coding sequence, recombinant DNA molecules comprising the lichenase coding sequences, recombinant...
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6090607 |
Enhanced expression of proteolytic enzymes in koji mold
The present invention has for an object a koji mold which expresses at least 2 times more endo- and exo-peptidases than the wild type strain of Aspergillus oryzae CNCM I-1882, and especially at...
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6017762 |
Cassette for the expression of an endothiapepsin precursor in Cryphonectria parasitica
The present invention relates to a new cassette for the expression of an endothiapepsin precursor in Cryphonectria parasitica, to a strain of this species transformed with this cassette, to a...
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5985627 |
Modified carboxypeptidase
A method for transamidating a peptide substrate having a P 1 amino acid residue with a positively charged side chain. According to the invention, carboxypeptidase Y is modified to substitute at...
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5888757 |
Cell wall assay
Disclosed are methods that can be used to (1) measure the level of polysaccharide in a sample; (2) measure the ability of a compound to degrade a polysaccharide; (3) measure the ability of a...
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5868868 |
Peg-modified proteases and methods of use in contact lens cleaning
The invention discloses PEG-modified proteases, compositions containing these modified enzymes, and methods for using them to clean contact lenses. The methods of the present invention are also...
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5843753 |
Metalloprotease having increased activity
The present invention relates to a novel metalloprotease obtainable from a fungus having increased proteolytic activity. Additionally, the invention related to isolated nucleic acid fragments...
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5840517 |
Process for preparing obesity protein analogs
The present invention is directed to an improved process for preparing in high yield an obesity protein analog using a dipeptidylaminopeptidase isolated from the slime mold, Dictyostelium discoideum.
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5723720 |
Process for the development of endophyte-infected plants
Beneficial endophytes which live within certain plants are known to provide desirable, cost-effective biological insect control. Many naturally occurring grasses host symbiotic endophytic fungi....
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5702934 |
Processes for producing an enzyme
The present invention is related to a process for producing an active enzyme comprising fermenting the proform of the active enzyme in the present of a proteolytic enzyme different from the active...
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5693520 |
Recombinant trypsin-like protease
An active recombinant trypsin-like protease enzyme comprising the amino acid residues 25-224 of the amino acid sequence of SEQ ID NO:2, as well as a DNA construct encoding the enzyme and comprising...
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5618690 |
Method of using an ER-located endoprotease
The invention concerns novel DNA molecules encoding a modified, endoplasmic reticulum-located "dibasic processing endoprotease" and the use of said endoplasmic reticulum-located "dibasic processing...
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5573923 |
Method for removing N-terminal dipeptides from precursor polypeptides with immobilized dipeptidylaminopeptidase from dictyostelium discoideum
A method for removing dipeptides from the amino terminus of precursor polypeptides to produce a polypeptide product is presented which comprises contacting the precursor polypeptide for sufficient...
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5565349 |
Dictyostelium dipeptidylaminopeptidase
A dipeptidylaminopeptidase (dDAP enzyme) and a method for isolating it from the culture medium of the cellular slime mold, Dictyostelium discoideum have been presented. The isolated dDAP enzyme has...
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5561051 |
Screen for inhibitors of chitinase
The present invention is directed to a method for screening samples for the identification of agents exhibiting potential fungicidal and insecticidal activity for a wide variety of agricultural,...
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5527483 |
Nonaqueous gelled automatic dishwashing composition containing enzymes
Nonaqueous gelled automatic dishwashing compositions containing a mixture of a protease enzyme and an amylase enzyme have been found to be very useful in the removal of protein and carbohydrate...
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5501975 |
DNA molecules encoding an ER-located endoprotease
The invention concerns novel DNA molecules encoding a modified, endoplasmic reticulum-located "dibasic processing endoprotease" and the use of said endoplasmic reticulum-located "dibasic processing...
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5472865 |
Protease from Dendryphiella arenaria DSM 6260 or Dendryphiella salina DSM 6332, process for making it and use as detergent additive
A protease obtainable from Dendryphiella arenaria DSM 6260 or Dendryphiella salina DSM 6332 is disclosed. The protease has a pl of approximately 9.1 as determined by isoelectric focusing, a...
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5468416 |
Detergent enzymes
This inventions is in the field of detergent enzymes. More specifically, the invention relates to the use of proteases from fungi of the genus Verticillium for detergent purposes.
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5443981 |
Acremonium typhinum ATCC 74228 which exhibits endoproteolytic activity
A crude membrane fraction of leaf sheath tissue of a grass endophytically infected by A. typhinum is produced. The extract exhibits endoproteolytic activity in the presence of detergent or after...
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5429765 |
Detergent and method for producing the same
A high density, enzyme-containing powder detergent composition including a combination of alkaline proteases for improved cleaning characteristics and a combination of different density sodium...
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5356805 |
Gamma-polyglutamate hydrolase
An enzyme produced by a microorganism belonging to the genus Myrothecium hydrolyzes γ-polyglutamic acid with an endo action to produce oligoglutamic acid consisting of 2 to 4 glutamic acid residues.
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5332668 |
Protease with low thermostability derived from Mucor pusillus
A mutant fungus strain which produces a protease with low thermostability and low productivity was made from protease producing fungi and the gene coding for mutant enzyme is isolated from the...
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5288627 |
Endoprotease from Fusarium oxysporumDSM 2672 for use in detergents
An endoprotease preparation, comprising an isolated endoprotease is disclosed. The endoprotease is a serine protease, shows immunochemical idenity to a protease derived from Fusarium oxysporum DSM...
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5278062 |
Proteolytic enzymes
This disclosure relates to a novel class of serine proteases isolated from a culture medium of fungus Tritirachium album. The serine proteases disclosed have a high degree of stability in detergent...
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5268280 |
Method for glucose isomerization using xylose isomerase purified from Thermotoga Maritima and Thermotoga Neapolitana
This invention is in the field of glucose isomerization enzymes. More specifically, the invention is directed to a novel xylose isomerase, a process for the preparation of this enzyme, the use of...
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5187081 |
Process for preparing protease from Endothia parasitica using glucanases to reduce viscosity
The present invention relates to a process for preparing protease from Endothia parasitica, wherein a glucanase or a mixture of glucanases acting on the viscosity increasing polysaccharides...
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5047240 |
Method for producing a proteolytic complex stimulating the activity of the pancreas and its application in zootechny
Method for producing a proteolytic complex formed after cultivation of a strain of Streptomyces fradiae while maintaining the pH of the culture medium between 7 and 7.5, and extracting said complex...
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4987077 |
Preparations of protease enzymes derived from entomopathogenic fungi
The invention provides an enzyme preparation comprising at least one protease derived from an entomopathogenic fungus of one of the following genera: Metarhizium, Beauvaria, Verticillium, and...
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4927558 |
Proteolytic detergent additive and compositions containing the same
Combinations of alkaline Bacillus protease with alkaline fungal or actinomycete protease show improved detergency. Proteases obtainable from Fusarium sp. or Paecilomyces sp. (fungal) and...
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4797361 |
Microorganism and process
This invention includes a process for producing and using increased quantities of extracellular glycoprotein (particularly cellulolytic) enzymes by permitting the enzyme-producing microbial strain...
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