Matches 51 - 100 out of 335 < 1 2 3 4 5 6 7 >


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7741438 Methods and compositions involving endopeptidases PepO2 and PepO3  
The present invention concerns the methods and compositions involving endopeptidase enzymes, especially PepO2 and PepO3 from L. helveticus, and their use in reducing bitterness by cleaving bitter...
RE41328 Purification of Heparinase I, II and III from Flavobacterium heparinum  
A purified heparinase I, II and III free of lyase activity and each having a molecular weight of 42,800 84,100, 70,800, respectively, are produced by culturing Flavobacterium heparinum. The...
7662935 Processing of peptides and proteins  
The invention provides novel methionine aminopeptidase enzymes and their use.
7588910 Hemoglobin A1c determination method, enzyme to be used therefor, and production method thereof  
There is provided a method for specifically determining a glycated β-chain N-terminal of glycated hemoglobin using enzymes without a separation operation, and a determination reagent kit therefor....
7524655 Synthesis of oligosaccharides, glycolipids, and glycoproteins using bacterial glycosyltransferases  
This invention provides nucleic acid and amino acid sequences of fucosyltransferases from Helicobactor pylori. The invention also provides methods to use the fucosyltransferases to synthesize...
7498148 Method for universal enzymatic production of bioactive peptides  
The invention provides methods for making peptides from a polypeptide containing at least one copy of the peptide using clostripain to excise the peptide from the polypeptide. The methods enable...
7485447 Proteases and methods for producing them  
A secreted proteolytic polypeptide comprising at least three non-polar or uncharged polar amino acids within the last four amino acids of the C-terminus of the polypeptide, encoding...
7452701 Methods for the preparation of β-amino acids  
Purified β-amino acids are of considerable interest in the preparation of pharmacologically active compounds and industrial precursors. Although enantiomerically pure β-amino acids can be produced...
7449305 Method of pre-treating sample for measuring saccharified amine and method of measuring saccharified amine  
The present invention provides a method of pretreating a sample containing a glycated amine as an analyte, thereby enabling highly reliable measurement of a glycated amine. A glycated amino acid...
7410638 Bacterial strains, genes and enzymes for control of bacterial diseases by quenching quorum-sensing signals  
The present invention relates to isolated nucleic acid molecules encoding an autoinducer inactivation protein, wherein the encoded protein comprises an amino acid sequence selected from the group...
7407789 Recombinant staphylokinase derivatives and the preparation and applications thereof  
The present invention relates to the biotechnology field, more particularly, to novel recombinant staphylokinase (RGD/KGD-Sak) derivatives and the preparation the thereof. The derivatives, have a...
7354745 Method for producing L-β-lysine  
Purified β-amino acids are of considerable interest in the preparation of pharmacologically active compounds. Although enantiomerically pure β-amino acids, such as L-β-lysine, can be produced by...
7332320 Protease producing an altered immunogenic response and methods of making and using the same  
The present invention provides novel protein variants that exhibit reduced immunogenic responses, as compared to the parental proteins. The present invention further provides DNA molecules that...
7306937 Multiply-substituted protease variants  
Novel enzyme variants including protease variants derived from the DNA sequences of naturally-occurring or re-combinant non-human proteases are disclosed. The variant proteases, in general, are...
7297332 Protease, a gene therefor and the use thereof  
The present invention relates to a protease, and more specifically to a protease derived from Aranicola proteolyticus, a gene coding for said enzyme, a gene expression system for said protease, a...
7297528 Alkaline protease  
An alkaline protease having the following properties; a gene encoding the same; a microorganism producing the same; and washing compositions containing the same; (i) acting over a broad pH value...
7288389 Peptide-forming enzyme gene  
DNA and recombinant DNA that encode a peptide-forming enzyme, a method for producing a peptide-forming enzyme, and a method for producing a dipeptide are disclosed. A method for producing a...
7288401 Protease variants and compositions  
The present invention relates to enzymes produced by mutating the genes for a number of subtilases and expressing the mutated genes in suitable hosts are presented. The enzymes exhibit improved...
7232670 Targeting proteins to cells expressing mannose receptors via expression in insect cells  
The present invention is based on the discovery that proteins produced in insect cell cultures are glycosylated in a unique manner that causes them to be selectively imported by cells that express...
7208310 Proteases  
The present invention relates to proteases of high specific activity homologous to proteases derived from Nocardiopsis, and the production thereof by the wild-type, and in recombinant host cells...
7192757 Subtilase variants  
The present invention relates to subtilase variants having a reduced tendency towards inhibition by substances present in eggs, such as trypsin inhibitor type IV-0. In particular, the variants...
7192730 Thermostable proteolytic enzymes and uses thereof in peptide and protein synthesis  
The subject invention pertains to new thermostable enzymes and the use of these enzymes both in proteolysis as well as protein and polypeptide synthesis. The subject invention further concerns...
7122514 Compositions and methods for treatment of staphylococcal infection while suppressing formation of antibiotic-resistant strains  
Co-administration of a lysostaphin or other anti-staphylococcal agent which cleaves cross-links of peptidoglycans of staphylococci cell walls such as lysostaphin and an antibiotic effective...
7109015 Removal of N-terminal methionine from proteins by engineered methionine aminopeptidase  
The present invention provides methionine aminopeptidases (MetAPs) with a broad substrate range, particularly those capable of removing the N-terminal Met from bulky or acidic penultimate...
7098017 Protease variants and compositions  
The present invention relates to enzymes produced by mutating the genes for a number of subtilases and expressing the mutated genes in suitable hosts are presented. The enzymes exhibit improved...
6962703 Clostridial toxin derivatives able to modify peripheral sensory afferent functions  
The invention relates to an agent specific for peripheral sensory afferents. The agent may inhibit the transmission of signals between a primary sensory afferent and a projection neutron by...
6955886 Scintillation proximity assay for the detection of peptidoglycan synthesis  
The invention provides a scintillation proximity assay for detecting peptidoglycan synthesis. The assay is especially suitable for high throughput screening of compounds affecting peptidoglycan...
6955907 Alkaline, protease VapK suitable for laundry detergent, VapK gene, recombinant expression vector, and transformed microorganisms  
A novel alkaline protease VapK suitable for a laundry detergent is disclosed. The gene vapk coding for the protease VapK, the recombinant plasmids containing said gene, and the transformed V....
6946128 Protease conjugates having sterically protected epitope regions  
The present disclosure relates to subtilisin protease conjugate comprising a protease moiety and one or more addition moieties. Each addition moiety is covalently attached to an epitope protection...
6939949 DNA repair enzymes, nucleic acids encoding DNA repair enzymes and methods of using them  
The invention provides novel DNA repair enzymes, genes encoding the enzymes, and methods of using these polypeptides and nucleic acids, including DNA repair.
6913895 Methods for assaying transglycosylase reactions, and for identifying inhibitors thereof  
This invention relates to the field of bacterial transglycosylase reactions. The invention is directed to methods for assaying for transglycosylase activity, methods of identifying inhibitors of...
6908757 Serine protease variants having amino acid deletions and substitutions  
The present invention relates to variants of serine proteases having decreased immunogenicity relative to their corresponding wild-type proteases. More particularly, the present invention relates...
6902733 Staphylokinase derivatives with polyethyleneglycol  
Methods for the identification, production and use of staphylokinase derivatives characterized by a reduced immunogenicity after administration in patients. The derivatives of the invention are...
6897041 Expression of recombinant mature lysostaphin  
A portion of the lysostaphin gene of Staphylococcus simulans has been cloned and overexpressed in the cytoplasm of E. coli to yield lysostaphin, in the absence of preprolysostaphin and...
6893855 Subtilase variants  
The present invention relates to subtilase variants having a reduced tendency towards inhibition by substances present in eggs, such as trypsin inhibitor type IV-0. In particular, the variants...
6887677 Compounds and methods for identifying compounds which inhibit a new class of aspartyl proteases  
Compounds and methods for designing and identifying compounds which inhibit TFPP-like aspartyl protease enzymes by targeting the aspartic acid residues of the active site or mimicking peptides...
6867032 Enzymatic unhairing agent for use in tanning for producing leather and method for enzymatic unhairing treatment  
The invention provides an enzymatic unhairing agent for use in an unhairing step in tanning for producing leather comprising an alkaline protease as an active component; a treatment solution...
6855513 Quorum sensing signaling in bacteria  
The invention provides methods for identifying a modulator of quorum sensing signaling in bacteria, and for identifying a quorum sensing controlled gene in bacteria. In addition, the invention...
6846664 Process for the preparation of protease inhibitor using novel alkalothermophilic bacillus sp  
The present invention relates to a novel strain of alkalothermophilic Bacillus sp. isolated from a hot spring at Vajeshwari, District Thane, The State of Maharashtra, India and deposited at...
6833262 Polypeptide having amidolytic activity for a serpin  
An isolated oral bacterial polypeptide having amidolytic activity for cleavage of denatured polypeptides and nondenatured serpin polypeptides and particularly a human α1-proteinase inhibitor...
6797503 Enzyme  
The present invention relates to a novel enzyme (α-GARE) which releases an amino acid residue having a glycated α-amino group (α-GA) from a glycated protein etc. and to bacterial strains producing...
6783764 Actinobacillus pleuropneumoniae subunit vaccine  
The present invention relates to live attenuated bacteria of the genus Actinobacillus pleuropneumoniae that have a mutation in an apxIV gene such that no functional ApxIV toxin can be produced....
6780629 Subtilase enzymes  
The present invention relates to subtilase enzymes of the I-S1 and I-S2 sub-groups having an additional amino acid in the active site loop (c) region from positions 125 to 132. The variant...
6777218 Subtilase enzymes having an improved wash performance on egg stains  
The present invention relates to novel subtilases having an improved wash performance on egg stains. The present invention also relates to isolated nucleic acid sequences encoding the subtilases,...
6753155 Protein biomarker for mustard chemical injury  
This invention relates to the discovery that toxicity to mustard may be evaluated by diagnostic test means disclosed herein. Upon electrophoretic separation (sodium dodocyl sulfate polyacrylamide...
6727085 Subtilase variants having an improved wash performance on egg stains  
The present invention relates to the use of a subtilase variant for removal of egg stains from laundry or from hard surfaces, where the subtilase variant comprises at least one additional amino...
6709834 Lipopolysaccharide α-2,3 sialytransferase of campylobacter jejuni and its uses  
The structure and specificity of a recombinant α2,3-sialyltransferase from Campylobacter spp., is disclosed. Also provided are methods for using the α2,3-sialyltransferase in the production of...
6682924 Protease variants and compositions  
The present invention relates to enzymes produced by mutating the genes for a number of subtilases and expressing the mutated genes in suitable hosts are presented. The enzymes exhibit improved...
6638503 STREPTOMYCES MEGASPORUS SD5, PROCESS FOR THE ISOLATION THEREOF, NOVEL FIBRINOLYTIC ENZYME PREPARED THEREFROM, PROCESS FOR THE PRODUCTION OF SAID ENZYME AND METHOD OF TREATMENT OF THROMBOLYTIC DISORDERS USING SAID ENZYME  
The present invention relates to a novel microorganism Streptomyces megasporus SD5. The present invention also relates to a process for the isolation of said Streptomyces megasporus SD5. The...
6627193 Methods and compositions for control of blood coagulation  
Methods for controlling blood coagulation, and suitable pharmaceutical compositions that include a polypeptide that enhances the anticoagulation process (or inhibitors thereof for reversing the...

Matches 51 - 100 out of 335 < 1 2 3 4 5 6 7 >