|
Match
|
Document |
Document Title |
|
|
7618801 |
Streptomyces protease
Certain aspects of this disclosure relate to an isolated protease, and cleaning compositions containing the same. In some embodiments, the protease may comprise an amino acid sequence that is at...
|
|
|
7618796 |
Peptide-forming enzyme gene, peptide-forming enzyme, and peptide producing method
The present invention provides a method for producing dipeptide using inexpensively acquirable starting materials by an industrially advantageous and simple pathway. Dipeptide is produced from...
|
|
|
7604975 |
Glycosylated LPXTGases and uses thereof
An endopeptidase is described which shows specificity for cleavage of a LPXTG (SEQ ID NO: 1) motif found in the cell membranes of gram positive bacteria, having an apparent molecular weight of...
|
|
|
7595173 |
Low-cost production of peptides
The subject invention relates to a low cost method of producing peptides, including antimicrobial peptides (AMPs), by using microbes. The subject methods enable greatly improved yields of the...
|
|
|
7588910 |
Hemoglobin A1c determination method, enzyme to be used therefor, and production method thereof
There is provided a method for specifically determining a glycated β-chain N-terminal of glycated hemoglobin using enzymes without a separation operation, and a determination reagent kit therefor....
|
|
|
7585635 |
Method for detecting and analyzing protein interactions in vivo
Described are various methods of detecting and analyzing protein interactions in a cell. The specific protein interaction is detected by a permanent signal generated by a recombinase activity or...
|
|
|
7534934 |
Precise breeding
The present invention relates to a method for identifying and isolating native plant nucleic acid sequences that may function as T-DNAs or T-DNA border-like sequences, effecting the transfer of one...
|
|
|
7527947 |
Signal peptide for producing a polypeptide
The present invention relates to a method for producing a polypeptide comprising using a signal peptide, to nucleic acid constructs comprising a first nucleotide sequence encoding the signal...
|
|
|
7517678 |
Method for protein production
Provided is a novel comprising culturing host cells into which a foreign gene has been introduced for producing a protein in a soluble form encoded by the foreign gene, recombinant cells are...
|
|
|
7498305 |
Activated protein C variants with normal cytoprotective activity but reduced anticoagulant activity
Variants (mutants) of recombinant activated protein C (APC) or recombinant protein C (prodrug, capable of being converted to APC) that have substantial reductions in anticoagulant activity but that...
|
|
|
7485446 |
Stable retrovirus and methods of use
The present invention is a mutant retroviral protease which confers an increase in retroviral stability. Retroviruses expressing the instant mutant retroviral protease exhibit at least a 2-fold...
|
|
|
7482147 |
Ubiquitin protease
The invention provides isolated nucleic acids molecules and proteins, designated 27411, 23413, 22438, 23553, 25278, 26212, NARC SC1, NARC 10A, NARC 1, NARC 12, NARC 13, NARC17, NARC 25, NARC 3,...
|
|
|
7456269 |
Alzheimer's disease secretase, APP substrates thereof, and uses thereof
The present invention provides the enzyme and enzymatic procedures for cleaving the β secretase cleavage site of the APP protein and associated nucleic acids, peptides, vectors, cells and cell...
|
|
|
7435420 |
Dipeptidyl peptidase IV inhibitors for the treatment of anxiety
The present invention discloses a method for therapeutically treating an animal, including a human, for psychosomatic, depressive and neuropsychiatric diseases, such as anxiety, depression,...
|
|
|
7427498 |
Composition, methods and reagents for the synthesis of a soluble form of human PHEX
This invention relates to a soluble form of PHEX, PHEX being a type II integral membrane glycoprotein. This enzyme is the gene product of a phosphate-regulating gene with homologies to...
|
|
|
7410775 |
Method for making recombinant peptides or proteins using soluble endoproteases
The present invention relates to the expression and secretion in Saccharomyces cerevisiae of readily purifiable soluble variants of the Kex1 endopeptidase of Kluyveromyces lactis and the...
|
|
|
7407789 |
Recombinant staphylokinase derivatives and the preparation and applications thereof
The present invention relates to the biotechnology field, more particularly, to novel recombinant staphylokinase (RGD/KGD-Sak) derivatives and the preparation the thereof. The derivatives, have a...
|
|
|
7407653 |
Treatment of IgA1 deposition diseases
The present invention discloses the use of bacterial IgA1 proteases to treat IgA1 deposition in tissue and organs. Bacterial IgA1 proteases specifically cleave IgA1 molecules and thus provide a...
|
|
|
7402309 |
Phage-associated lytic enzymes for treatment of Bacillus anthracis and related conditions
The present disclosure relates to methods, compositions and articles of manufacture useful for the treatment of Bacillus anthracis and B. cereus bacteria and spores, and related conditions. The...
|
|
|
7393659 |
Analytical method for the determination of infant formula protein digestibility in vitro
A method for in vitro determination of the digestibility of proteins in a nutritional product. The method utilized gastric and intestinal enzymes that are standardized for in vitro digestion...
|
|
|
7393528 |
Biological pesticide
Methods for exterminating pests using compositions comprising at least one protease enzyme. A detergent component may also be utilized in such compositions.
|
|
|
7378512 |
Production of proteins by autoproteolytic cleavage
The present invention relates to a process for the production of a heterologous polypeptide with homogeneous N-terminus in a bacterial host cell, wherein the heterologous polypeptide is...
|
|
|
7371839 |
Alkaline proteases
The present invention relates to alkaline proteases having high specific activity and strong oxidant resistance. The present invention also relates to alkaline proteases having excellent detergency...
|
|
|
7368272 |
Expression of proteolytic enzymes in koji mold in the presence of carbon sources
The present invention refers to a koji mold capable of expressing proteolytic enzymes in the presence of a carbon source in at least the same amount as in the absence thereof. In particular, the...
|
|
|
7364892 |
Microbial trypsin mutants having chymotrypsin activity and nucleic acids encoding same
The present invention relates to microbial trypsin variants having chymotrypsin-like activity, comprising: (a) a one or more substitutions corresponding to positions 144, 193, 198, 201, 218, 223,...
|
|
|
7361493 |
Production of urokinase in a three-dimensional cell culture
Embodiments of a method for the production of human urokinase are disclosed. Also disclosed are embodiments of a cell culture well-suited for use with the disclosed method. The method involves...
|
|
|
7354749 |
Decellularisation of matrices
A method of preparing matrices or tissue engineered biomaterials for implantation, and in particular to a method of improving decellularisation of matrices or tissue engineered biomaterials prior...
|
|
|
7354734 |
Fungal proteins and nucleic acids encoding same
Disclosed herein are fungal nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, as well as derivatives, variants,...
|
|
|
7344856 |
Method of controlling cleavage by OmpT protease
Methods of using OmpT protease are provided. In particular, the invention provides for a method of controlling cleavage of a polypeptide by OmpT protease comprising, converting a sequence site...
|
|
|
7338792 |
Process for the preparation of D-pantothenic acid and/or salts thereof
The invention provides a process for the preparation of D-pantothenic acid and/or salts thereof or feedstuffs additives comprising these by fermentation of microorganisms of the Bacillus group,...
|
|
|
7329527 |
Serine proteases from gram-positive microorganisms
The present invention relates to the identification of novel serine proteases in Gram-positive microorganisms. The present invention provides the nuclei acid and amino acid sequences for the ...
|
|
|
7323558 |
Nucleic acids encoding dendritic cell transmembrane serine protease
Isolated Dendritic Cell Transmembrane Serine Proteases (DCTSPs), DNAs encoding such DCTSPs, and pharmaceutical and/or diagnostic compositions made therefrom, are disclosed. The isolated DCTSPs can...
|
|
|
7323327 |
Genes encoding novel proteolytic enzymes
The invention relates to newly identified gene sequences that encode novel proteases obtainable from Aspergillus niger . The invention features the full length gene sequence of the novel genes,...
|
|
|
7311935 |
Carboxypeptidase of cocoa
The present invention relates to a novel carboxypeptidase gene and the polypeptide encoded thereby. In particular, the present invention relates to the use of the present carboxypeptidase and...
|
|
|
7309595 |
Protein hydrolysates enriched in peptides having a carboxy terminal proline residue
The present invention provides An isolated polypeptide which has proline specific endoprotease activity, selected from the group consisting of:(a) a polypeptide which has an amino acid sequence...
|
|
|
7297513 |
Gene encoding glutathione synthetase from Candida utilis
A gene encoding glutathione synthetase from Candida utilis is provided and food containing γ-glutamylcysteine cysteine or cystenylglycine is produced by cultivating Candida utilis modified by...
|
|
|
7291494 |
Regulation of target protein activity through modifier proteins
The present invention is based on the discovery that a polypeptide containing the JAB subunit or the JAM domain has peptidase activity, e.g., isopeptidase activity. The present invention provides...
|
|
|
7288389 |
Peptide-forming enzyme gene
DNA and recombinant DNA that encode a peptide-forming enzyme, a method for producing a peptide-forming enzyme, and a method for producing a dipeptide are disclosed. A method for producing a...
|
|
|
7288388 |
Peptide-forming enzyme gene, peptide-forming enzyme, and peptide producing method
The present invention provides a method for producing dipeptide using inexpensively acquirable starting materials by an industrially advantageous and simple pathway. Dipeptide is produced from...
|
|
|
7279317 |
Modulation of COP9 signalsome isopeptidase activity
Methods for identifying agents that can increase or decrease the isopeptidase activity of a COP9 signalsome (CSN) are provided, as are agent identified using such screening assays. In addition,...
|
|
|
7264922 |
Method of reducing complement - mediated disruption of cells
Disclosed is a pO157 plasmid-specified polypeptide found in E. coli EDL933 and other E. coli that binds to and cleaves C1-esterase inhibitor, and antibodies specific for the polypeptide. Also...
|
|
|
7258856 |
Proteases from Carica having mitogenic activity and their methods of use
Proteases having mitogenic activity isolated from the genus Carica are provided. In particular the proteases are cysteine proteases isolated from Carica candamarcensis. In addition, the...
|
|
|
7250503 |
Nucleic acid molecules encoding clot-specific streptokinase fusion proteins possessing altered plasminogen activation characteristics
The present invention provides polynucleotides encoding clot-specific streptokinase proteins possessing altered plasminogen characteristics, including enhanced fibrin selectivity. The kinetics of...
|
|
|
7241609 |
Soluble endoproteases for the in vitro processing of recombinant proteins
The present invention relates to the expression and secretion in Saccharomyces cerevisiae of readily purifiable soluble variants of the Kex1 endopeptidase of Kluyveromyces lactis and the...
|
|
|
7235638 |
Coagulation factor VII derivatives
The present invention relates to novel human coagulation Factor VII polypeptides, Factor VII derivatives as well as polynucleotide constructs encoding such polypeptides, vectors and host cells...
|
|
|
7229787 |
Method of N-terminal cleavage using an aminopeptidase
A gram-negative bacterial cell is described that is deficient in a chromosomal gene present in a wild-type such cell which gene shares at least 80% sequence identity with the native sequence of the...
|
|
|
7223595 |
Use of purified Streptomyces griseus trypsin for production of a biomass of cells and viral propagation
The present invention provides methods of isolation and purification of Streptomyces griseus trypsin (SGT) from PRONASE protease mixture in a single affinity chromatography step and uses of the...
|
|
|
7214479 |
E. coli O157:H7 C1-INH-binding protein and methods of use
Disclosed is a pO157 plasmid-specified polypeptide found in E. coli EDL933 and other E. coli that binds to and cleaves C1-esterase inhibitor, and antibodies specific for the polypeptide. Also...
|
|
|
7211650 |
Purification of fibrinogen from fluids by precipitation and hydrophoic chromatography
The present invention provides a method for the part purification of fibrinogen from milk, the method comprising the transfer of protease enzyme which is present in the milk, into the whey phase...
|
|
|
7208308 |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid...
|