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7615362 |
Isolated xylanase gene with mutations and site-specific mutagenesis method thereof
A mutated xylanase gene with a broad pH range of reaction includes a forty-first amino acid or a twenty-first amino acid generated from transforming asparagine to aspartic acid so as to form the...
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7604958 |
Synthetic mammalian α-N-acetylglucosaminidase and genetic sequences encoding same
The present invention relates generally to mammalian α-N-acetyglucosaminidase and to genetic sequences encoding same and to their use in the investigation, diagnosis and treatment of subjects...
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7582463 |
Non-reducing saccharide-forming enzyme, trehalose-releasing enzyme, and process for producing saccharides using the enzymes
A non-reducing saccharide-forming enzyme and a trehalose-releasing enzyme, which have an optimum temperature in a medium temperature range, i.e., a temperature of over 40 or 45° C. but below 60°...
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7576070 |
Method for producing pectin hydrolysis products
The present invention relates to methods for the production of pectin hydrolysis products, the pectin hydrolysis products produced in this manner, as well as their use.
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7572613 |
Drug delivery system for accelerated subcutaneous absorption
A method for accelerating subcutaneous absorption of a fluid or drug into the systemic circulation of a specific targeted tissue. A first drug operative to produce local capillary vasodilatation...
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7566556 |
Enhancing enzyme thermostability by mixing with sorghum liquor waste
A composition containing a thermolabile protein admixed with a liquor waste. Also disclosed is a method of preparing such a composition which contains a protein with enhanced thermostability.
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7560126 |
Amylases, nucleic acids encoding them and methods for making and using them
In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and...
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7527958 |
Truncated 1,3-1,4-β-D-glucanase
A truncated 1,3-1,4-β-D-glucanase. Also disclosed are related nucleic acid, vector, host cell, and preparation method.
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7527947 |
Signal peptide for producing a polypeptide
The present invention relates to a method for producing a polypeptide comprising using a signal peptide, to nucleic acid constructs comprising a first nucleotide sequence encoding the signal...
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7510860 |
Xylanases with enhanced thermophilicity and alkalophilicity
The present invention provides a xylanase, or a modified xylanase enzyme comprising at least one substituted amino acid residue at a position selected from the group consisting of amino acid 11,...
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7510857 |
Thermostable cellulase and methods of use
A Clostridium thermocellum thermostable cellulase enzyme with both endocellulase activity and exocellulase activity that is able to degrade cellulose in the absence of scaffolding and other...
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7445922 |
Zygomycetes-derived endoglucanase enzyme lacking cellulose-binding domain
This invention relates to a protein that is a Zygomycetes -derived endoglucanase lacking the cellulose-binding domain and exhibits endoglucanase activity, and a method for using the same. This...
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7432099 |
Amylase variants
The present invention relates to variants (mutants) of polypeptides, in particular Termamyl-like alpha-amylases, which variant has alpha-amylase activity and exhibits an alteration in at least one...
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7407677 |
Enzymes having alpha amylase activity and methods of use thereof
The invention relates to alpha amylases and to polynucleotides encoding the alpha amylases. In addition methods of designing new alpha amylases and methods of use thereof are also provided. The...
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7393929 |
Inhibitors of cellulolytic, xylanolytic and β-glucanolytic enzymes
The present invention concerns an inhibitor of xylanolytic and/or β-glucanolytic enzymes, method for obtaining the inhibitor, said inhibitor and processes for obtaining micro-organism, plant or...
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7378264 |
α-amylase mutants
The present invention relates to a method of constructing a variant of a parent Termamyl-like α-amylase, which variant has α-amylase activity and at least one altered property as compared to the...
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7371552 |
Polypeptide
We disclose a food additive comprising a PS4 variant polypeptide, in which the PS4 variant polypeptide is derivable from a parent polypeptide having non-maltogenic exoamylase activity, in which the...
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7351410 |
Treatment of Pompe's disease
The invention provides methods of treating Pompe's disease using human acid alpha glucosidase. A preferred treatment regime comprises administering greater than 10 mg/kg body weight per week to a...
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7335503 |
Expression of granular starch hydrolyzing enzyme in Trichoderma
The present invention relates to filamentous fungal host cells and particularly Trichoderma host cells useful for the production of heterologous granular starch hydrolyzing enzymes having...
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7323322 |
Ethanol production from transformed Zymobacter microorganisms
This invention provides transformed microorganisms which can produce ethanol from cellooligosaccharide, by introducing β-glucosidase gene by recombinant DNA method, into microorganisms belonging...
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7312056 |
Enhancement of enzyme activity through purification and immobilization
An improved method of making an immobilized enzyme comprising (a) treating an immobilization support with an aqueous solution comprising a cross-linking agent and polymeric aldehyde species and...
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7273741 |
Copper tolerant yeast and pectinases produced by the yeast
The object of the present invention is to provide a yeast which is tolerant to copper and which can incorporate copper at a high concentration, and also a method of removing or recovering copper...
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7244605 |
Polypeptides having beta-glucosidase activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having beta-glucosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid...
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7241442 |
Method for producing proteins suitable for treating lysosomal storage disorders
The present invention is based on the discovery that proteins produced in insect cell cultures are glycosylated in a unique manner that causes them to be selectively imported by cells that express...
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7192746 |
α-Isomaltosyltransferase, process for producing the same and use thereof
The object of the present invention is to provide an α-isomaltosyl-transferring enzyme which forms a cyclotetrasaccharide having the structure of...
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7179634 |
Methods for producing a polypeptide in a Bacillus cell
The present invention relates to methods for producing a polypeptide, comprising: (a) cultivating a Bacillus host cell in a medium conducive for the production of the polypeptide, wherein the ...
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7153818 |
Amylolytic enzyme extracted from bacillus sp. A 7-7 (DSM 12368) and washing and cleaning agents containing this novel amylolytic enzyme
The invention relates to a novel amylolytic enzyme extracted from the micro-organism Bacillus sp. A7-7 (DSM 12368), to sufficiently similar proteins having an amylolytic function, to methods for...
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7138263 |
Endoglucanase enzyme NCE5 and cellulase preparations containing the same
There is provided an endoglucanase enzyme, which is useful for reducing fuzz of regenerated cellulose-containing fabrics, improving the touch and appearance, color clarification, localized...
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7138262 |
High mannose proteins and methods of making high mannose proteins
The invention features a method of producing a high mannose glucocerebrosidase (hmGCB) which includes: providing a cell which is capable of expressing glucocerebrosidase (GCB), and allowing...
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7122365 |
Glucoamylase variants
The invention relates to a variant of a parent fungal glucoamylase, which exhibits improved thermal stability and/or increased specific activity using saccharide substrates.
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7115409 |
α-amylase mutants
The present invention relates to a method of constructing a variant of a parent Termamyl-like α-amylase, which variant has α-amylase activity and at least one altered property as compared to the...
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7115408 |
Method of stabilizing hyaluronidase with annexin II
This invention relates generally to the use of annexin II for the purpose of stabilizing a hyaluronidase enzyme for administration to the eyes of humans or other mammals.
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7109014 |
Diglycosidase isolated from microorganisms
This invention relates to a novel microorganism-derived enzyme having an activity to cut disaccharide glycosides (particularly, β-primeveroside and/or analogous disaccharide glycosides) in...
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7105330 |
Human plasma hyaluronidase
The invention is based on the discovery of methods for purification of an acid active hyaluronidase found in human plasma (hpHAse), including both biochemical and immunoaffinity purification...
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7094563 |
Isolation and composition of novel glycosidases
Substantially pure glycosidases capable for cleaving selected glycosidic bonds have been described including glycosidases isolated from Xanthomonas and recombinant glycosidases. Substrate...
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7081355 |
Enzyme isolated from a Bifidobacterium
The present invention concerns a new β-galactosidase with transgalactosylating activity isolated from Bifidobacterium bifidum and a truncated enzyme where the C-terminal end of the...
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7078212 |
Mutant α-amylases
The invention relates to a mutant α-amylase obtained by making replacement or deletion of at least one of amino acid residues such as the 167th Gln, 169th Tyr and 178th Ala in the amino acid...
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7060474 |
Carbohydrate oxidase and use thereof in baking
The properties of dough or bread can be improved by the addition of a carbohydrate oxidase which can oxidize the reducing end of an oligosaccharide more efficiently than the corresponding...
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7056691 |
Assays for identifying α-galactosidases
The invention relates to α-galactosidase and to polynucleotides encoding the α-galactosidase. In addition methods of designing new α-galactosidases and method of use thereof are also provided....
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7049124 |
Hyaluronidase from the Hirudinaria manillensis isolation, purification and recombinant method of production
The present invention relates to the isolation, purification and characterization of a hyaluronidase which derives from the tropical leech Hirudinaria manillensis . Therefore, according to this...
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7041487 |
Recombinant α-L-iduronidase, methods for producing and purifying the same and methods for treating diseases caused by deficiencies thereof
The present invention provides a recombinant α-L-iduronidase and biologically active fragments and mutants thereof, methods to produce and purify this enzyme as well as methods to treat certain...
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7018805 |
α-Amylase assay and uses thereof
This invention relates to methods and kits for measuring α-amylase activity in grain and plant products such as flour or stock.
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7012173 |
Promoter system and production and use of the same
The present invention relates to nucleic acids coding for promoters, which are both tapetum-specific and pollen-specific, as well as the use thereof for producing male sterile plants.
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6960454 |
Methods for making and using a thermophilic enzyme as a β-glycosidase
The invention relates to a thermophilic enzyme having β-glycosidase activity which comprises the amino acid sequence of SEQ ID NO: 2 in which one or a plurality of amino acid residues may be...
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6953682 |
Nucleic acid sequences encoding adenylate kinase, phospholipid scramblase-like, DNA fragmentation factor-like, phosphatidylserine synthase-like, and atpase-like molecules and uses therefor
The invention provides isolated nucleic acids molecules that encode novel polypeptides. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing the...
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6951969 |
Nucleic acid molecules which code for enzymes derived from wheat and which are involved in the synthesis of starch
Nucleic acid molecules are described which encode enzymes involved in starch synthasis in plants. These enzymes are wheat isoamylases. The invention furthermore relates to vectors and host cells...
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6939703 |
Amylolytic enzymes derived from the B.licheniformis α-amylase, having improved characteristics
The present invention relates to novel amylolytic enzymes having improved characteristics for the use in starch degradation, in textile or paper desizing and in household detergent compositions....
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6927053 |
Dual component dental composition containing enzyme
A two component desensitizing dentifrice composition is disclosed which comprises a first dentifrice component containing an enzyme such as papain and a second dentifrice component containing an...
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6900046 |
Human ATPase proteins and polynucleotides encoding the same
Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
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6900039 |
Carbohydrate oxidase and use thereof in baking
The properties of dough or bread can be improved by the addition of a carbohydrate oxidase which can oxidize the reducing end of an oligosaccharide more efficiently than the corresponding...
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