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8178085 |
Methods of proliferating stem cells
The invention relates to methods of proliferating stem cells. More particularly, the invention relates to the use of glycosaminoglycans or proteoglycans to promote the growth of stem cells in ex...
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RE43389 |
Vessel for blood sampling
The present invention relates to a vessel for withdrawing blood, the vessel containing a solution which comprises a guanidinium salt, a buffer substance, a reducing agent, and/or a detergent as...
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8163275 |
Multi-lineage progenitor cells
Fetal blood multi-lineage progenitor cells that are capable of a wide spectrum of transdifferentiation are described.
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8163470 |
Simulated 5-part differential leukocyte granules, the method for preparing the same and control products and calibrators comprising the same
A method for preparing five-part differential leukocyte analogs from red blood cells includes selecting appropriate red blood cells; treating the red blood cells with a multi-functional reagent...
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8163559 |
White blood cell differentiation reagent and method
A reagent for four-part differentiation of white blood cells is provided. In one embodiment the reagent has an osmolality below 50 mOsm/kg H2O. A method for differentiating white blood cells using...
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8163513 |
Method for determining the total clotting activity of a blood or plasma sample
The invention relates to a method for determining the total clotting activity of a blood or plasma sample, characterized in that a highly specific, reversible thrombin inhibitor is added to a blood...
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8158339 |
Method of preserving a platelet concentrate under elevated xenon concentration and pressure with refrigeration
Provides are improved methods for storing platelets and compositions that contain stored platelets for use in transfusions. The method entails obtaining a platelet concentrate from blood obtained...
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8148094 |
Methods and compositions for detecting the activation state of multiple proteins in single cells
The invention provides methods and compositions for simultaneously detecting the activation state of a plurality of proteins in single cells using flow cytometry. The invention further provides...
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8148101 |
Method for classifying and counting bacteria in body fluids
A method for distinguishing erythroblasts from bacteria by automated hematology analyzers, such as, for example, the CELL-DYN® 4000 automated hematology analyzer and the CELL-DYN® Sapphire™ aut...
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8142992 |
Platelet preservation package comprising a short to ultra-short acting antiplatelet agent and anticoagulant with an oxygen carrier
The present invention relates to compositions and methods for storing platelets to preserve the function and freshness of the platelets. More particularly, the present invention relates to the use...
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8142995 |
Method for assessing arteriosclerosis and diabetic nephropathy
A method for assessing arteriosclerosis comprising measuring the serotonin level in whole blood, serum or platelet-rich plasma and rating the serotonin level on such a scale that the lower it is,...
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8142993 |
Method of preparing neutrophil-depleted platelet-rich plasma
Methods of producing neutrophil-depleted platelet-rich plasma by passing a blood, platelet or platelet-rich plasma fraction through a narrow, twisted and/or charged environment to remove...
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8143064 |
Reagents and methods for classifying leukocytes
A reagent for classification of leukocytes includes (a) at least two cationic surfactants; (b) at least one organic compound bearing a hydrophobic group and an anionic group; (c) a buffer for...
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8137967 |
In-vitro fertilization systems with spermatozoa separated into X-chromosome and Y-chromosome bearing populations
An IVF system for successfully utilizing spermatozoa separated into X-chromosome bearing and into Y-chromosome bearing population for insemination. The IVF system includes fertilization medium that...
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8137903 |
Method for magnetic separation of red blood cells from a patient sample
A method for separating components from a patient sample is provided. In particular, the present invention provides a method for the separation of red blood cells or red blood cell components from...
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8129103 |
Use of a platelet preservation composition comprising a short to ultra-short acting antiplatelet agent and anticoagulant with an oxygen carrier
The present invention relates to compositions and methods for storing platelets to preserve the function and freshness of the platelets. More particularly, the present invention relates to the use...
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8129104 |
Platelet preservation composition comprising a short to ultra-short acting antiplatelet agent and anticoagulant with hemoglobin
The present invention relates to compositions and methods for storing platelets to preserve the function and freshness of the platelets. More particularly, the present invention relates to the use...
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8124362 |
Nonseparation assay methods
Assay methods are disclosed involving specific binding reactions which are simplified compared to known methods. A compound capable of producing chemiluminescence is immobilized on a solid support...
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8114680 |
Buffy coat separator float system and method
A tube and float system for use in separation and axial expansion of the buffy coat includes a transparent or semi-transparent, flexible sample tube and a rigid separator float having a specific...
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8114580 |
Simulation of normal fresh blood platelets for reference control
The present invention provides for novel analogs of fresh human platelets for use in hematological instrument. Methods for preparing such analogs are also described.
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8105491 |
Metabolic detoxification and method
An extracorporeal filtration and detoxification system and method generally comprise separating ultrafiltrate from cellular components of blood, treating the ultrafiltrate independently of the...
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8101077 |
Device for separating platelets from fluid suspensions
A device for separating platelets from a fluid suspension comprises a mixing chamber operable to receive and mix fluid suspensions and an aggregating agent to form platelet aggregates and residual...
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8101369 |
Diagnose device for measuring the ratio of proteins with similar structure
The present invention relates to a diagnostic device for measuring the ratio of similar structural proteins among the proteins secreted in a liquid test sample taken from diagnosis subject. In...
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8097403 |
Freeze-dried platelets, method of making and method of use as a diagnostic agent
The present invention provides freeze-dried platelets and compositions comprising freeze-dried platelets for use as a diagnostic and calibration reagent for blood coagulation function. The...
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8097425 |
Multiplex protein fractionation
The invention provides methods, compositions, and kits for multiplex fractionation of proteins in a sample. Protein-binding molecules, such as small epitope antibodies or small epitope aptamers,...
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8088265 |
Cell separation
A process for separating a cell type from a mixture of cell types by electrophoresis comprising providing a sample containing a mixture of cell types to a sample chamber of membrane-based...
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8080424 |
Method and a blood oxygen tester for detecting the arterial or venous blood
A method and a blood oxygen tester for determining whether a blood sample is arterial or venous blood are disclosed. A blood oxygen tester for determining whether a blood sample is arterial or...
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8075782 |
Counter-pressure filtration of proteins
A method is disclosed for filtering a protein in a liquid mixture in a manner that does not substantially damage or otherwise limit the recovery of the protein in the filtration filtrate. The...
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8075781 |
Counter-pressure filtration of proteins
A method is disclosed for filtering a protein in a liquid mixture in a manner that does not substantially damage or otherwise limit the recovery of the protein in the filtration filtrate. The...
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8071326 |
Method and apparatus for viable and nonviable prokaryotic and eukaryotic cell quantitation
A rapid method for the quantitation of various live cell types is described. This new cell fluorescence method correlates with other methods of enumerating cells such as the standard plate count,...
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8071282 |
Method of storing red blood cells with an acidic additive solution under oxygen depletion
There is provided compositions and methods for the storage of red blood cells. The compositions are additive solutions comprising adenine, dextrose, mannitol, NaH2PO4, and optionally NaCl and/or...
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8071284 |
Methods and compositions for determining altered susceptibility of HIV-1 to anti-HIV drugs
This invention relates, in part, to methods and compositions for determining altered susceptibility of a human immunodeficiency virus (“HIV”) to the non-nucleoside reverse transcriptase inh...
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8067151 |
Cold storage of pegylated platelets at about or below 0° C.
A method for storing and using platelets and an associated platelet structure. At least one modified platelet is formed. Each modified platelet includes a platelet and at least one polymerated...
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8067602 |
Asymmetric cyanine fluorescent dyes, compositions and their use in staining biological samples
Asymmetric cyanine fluorescent dyes are represented by general formula I. These kinds of dyes may be used as a staining agent for nucleic acids, with the spectra at 600-900 nm in the near-infrared...
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8062881 |
Method for making a polymer blend for reducing protein binding to surfaces
Hydrophobic polymer surfaces whose level of protein binding is less than about 50-80 ng/cm2 are achieved by: (1) applying a coating solution composed of a solvent and a non-ionic surfactant having...
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8062837 |
Plasma-depleted, not erythrocyte-depleted, cord blood compositions and method of making
The umbilical cord blood (UCB) compositions of the present invention possess the unique features of having plasma that is substantially depleted from the UCB unit and red blood cells (RBC) that are...
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8053235 |
Methods of generating antigen-specific CD4+CD25+regulatory T cells, compositions and methods of use
The present invention provides methods for generating mammalian T cell populations comprising antigen-specific CD4+CD25+ regulatory T cells from freshly isolated CD4+CD25− T cells. The method c...
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8048639 |
Method for evaluating risk in multiple sclerosis
The invention relates to methods and reagents for diagnosing and assessing the prognosis of multiple sclerosis.
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8048620 |
Method for enhancing the detection of contamination in a cellular blood product by covalently binding a hydrophilic polymer to the cell membrane
A method for preventing bacterial biofilm formation in a blood product, the method comprising modifying a blood product with a polymer selected from the group consisting of polyethylene glycol...
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8048619 |
Method of treating a hematopoietic associated disease or disorder with plasma-depleted, but not erythrocyte-depleted cord blood compositions
The umbilical cord blood (UCB) compositions of the present invention possess the unique features of having plasma that is substantially depleted from the UCB unit and red blood cells (RBC) that are...
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8044051 |
Methods and compositions for the production of high concentration alloxazine solutions
Methods are provided for preparation of compositions having an enhanced level of soluble alloxazine, as compared to compositions prepared using conventional techniques. Compositions and a...
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8034576 |
Xanthurenic acid derivative pharmaceutical compositions and methods related thereto
The present invention relates to diuretic pharmaceutical compositions and methods and in particular to certain derivatives of the formula I: or a prodrug or pharmaceutically acceptable salt...
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8030069 |
Materials and procedures for the purification of cells
The subject invention provides new materials and methods for the efficient isolation and purification of stem cells. Specifically, conductive immunopolymers with stem cell specific antibodies can...
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8030016 |
Method for screening for vitamin D receptor ligands
The present invention relates to a screening method for a compound and includes a step of detecting binding between a vitamin D receptor and CDP. A novel method enabling screening in vitro of a...
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8029978 |
Processing method for the long-term stabilization of biological red blood cell volume
The present invention relates to a processing method for long-term stabilization of biological red blood cell volume. The red blood cells can be further used in reference materials and calibrators...
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8017726 |
Anti-inflammatory compounds and uses thereof
The present invention provides anti-inflammatory compounds, pharmaceutical compositions thereof, and methods of use thereof for treating inflammatory disorders. The present invention also provides...
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8017110 |
Induction of and maintenance of nucleic acid damage in pathogens using riboflavin and light
A process for damaging and maintaining damage to the nucleic acids of pathogens such as white blood cells, bacteria and viruses which may be contained in blood or blood components. This process...
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8012705 |
Nonseparation assay methods
Assay methods are disclosed involving specific binding reactions which are simplified compared to known methods. A compound capable of producing chemiluminescence is immobilized on a solid support...
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8008032 |
Tagged ligands for enrichment of rare analytes from a mixed sample
Method of enriching specific cells from cellular samples are disclosed, comprising contacting in solution a cellular sample with affinity-tagged ligands (ATLs) each comprising a first ligand linked...
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8003339 |
Method for determining endoglycosidase (heparanase) enzyme activity
The present invention provides a method for determining endoglycosidase activity, and in particular of the heparanase type, in a sample, and also a method for detecting compounds that modulate the...
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