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7622290 |
Fungal lipolytic enzymes, nucleic acids encoding, and uses thereof
A fungal wild-type lipolytic enzyme having a higher ratio of activity on polar lipids compared with triglycerides, wherein the enzyme preferably has a phospholipid:triglyceride activity ratio of at...
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7622109 |
Plant gene and uses thereof
A novel gene isolated from Deschampsia antarctica coding for a lipase like protein is disclosed. A system for production of recombinant enzyme is also disclosed as well as use for the enzyme in...
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7611886 |
Enzymatic transformation of a prostaglandin (bimatoprost) intermediate
A method for the selective enzymatic acetylation of a bimatoprost intermediate is provided.
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7611880 |
Enzymatic ammonolysis process for the preparation of intermediates for DPP IV inhibitors
An enzymatic ammonolysis process is provided for the preparation of intermediates used in preparing dipeptidyl peptidase IV inhibitors wherein the enzyme Candida antarctica lipase-B is used to...
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7598053 |
Plant gene and uses thereof
A novel gene isolated from Deschampsia antarctica coding for a lipase like protein is disclosed. A system for production of recombinant enzyme is also disclosed as well as uses for the enzyme.
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7588925 |
Phospholipases and uses thereof
The invention relates to a newly identified polynucleotide sequence comprising a gene that encodes a novel phospholipase isolated from Aspergillus niger . The invention features the full length...
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7582442 |
Methods and compositions for using aleveolar macrophage phospholipase A2
The present invention is directed to methods and compositions for improving pulmonary surfactant catabolism. More specifically, the specification describes methods and compositions for making and...
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7531316 |
High throughput assay of Lp-PLA2 activity
This invention relates to a method for determining the activity of Lp-PLA2 in a plurality of samples from animals. The invention also relates to a kit for determining Lp-PLA2 activity in a...
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7527947 |
Signal peptide for producing a polypeptide
The present invention relates to a method for producing a polypeptide comprising using a signal peptide, to nucleic acid constructs comprising a first nucleotide sequence encoding the signal...
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7511005 |
Lipolytic enzyme elip
The present invention provides a novel nucleic acid sequence, designated ELIP, encoding a lipolytic enzyme and the corresponding encoded amino acid sequences. The invention also provides expression...
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7485445 |
Plant gene and uses thereof
A novel gene isolated from Deschampsia antarctica coding for a lipase like protein is disclosed. A system for production of recombinant enzyme is also disclosed as well as uses for the enzyme.
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7473541 |
Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities
Isolated novel and purified and characterized phospholipase A 2 , referred to herein as calcium-independent phospholipase A 2 zeta (iPLA 2 zeta) having SEQ. ID. NO: 2 (See FIG. 1 ), and nucleic...
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7468266 |
Isolated genomic polynucleotide fragments that encode human lipoprotein-associated phospholipase A2
The invention is directed to isolated genomic polynucleotide fragments that encode human lipoprotein-associated phospholipase A2, vectors and hosts containing the fragment and fragments hybridizing...
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7455998 |
Methods for forming structurally defined organic molecules
Methods of forming organic molecules comprising contacting a hydrolase enzyme with an organic reactant are provided. Methods for forming an organosilicon molecule comprising contacting a hydrolase...
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7416869 |
Enzyme delivery systems, application in water based products
Aqueous enzyme delivery systems as well as aqueous cosmetics and personal care products were provided which comprise at least one stabile enzyme and a polyglycerol containing at least 15 carbons....
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7416867 |
Enzymatic production of (meth)acrylic acid esters
A method for the production of partially esterified (meth)acrylic acid esters of polyalcohols and the use thereof.
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7407786 |
Lipase genes
New lipase enzymes (both nucleic acids and polypeptides) are provided. Compositions which include these polypeptides, proteins, nucleic acids, recombinant cells, as well as methods involving the...
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7407779 |
Modification of solid 3-sn-phosphoglycerides
Methods for hydrolyzing solid ungranulated lysophosphatidylcholine with phospholipase A 2 are provided. Also disclosed are methods for making a lipid matrix of lysophosphatidylcholine,...
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7402414 |
Enzymatic process for deacetylation of a phenoxy-alkynyl acetate to the corresponding alcohol
A process for preparing the compound of formula II by reacting the compound of formula I with an enzyme that can hydrolyze the ester bond:
where * indicates a chiral center, R 1 and R 2 ...
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7396667 |
Enzymatic depolymerization process of polylactic acid, and producing process of polylactic acid using depolymerization product
A depolymerizing process of polylactic acid, wherein the polylactic acid is depolymerized in the presence of a hydrolase in an organic solvent or a supercritical fluid, thereby producing a...
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7384787 |
Increasing perhydrolase activity in esterases and/or lipases
The invention provides for methods of modifying n esterase or a lipase enzyme to introduce perhydrolase activity or to increase the already-existing perhydrolase activity. The invention also...
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7355004 |
Protein lipase inhibitor for flour and dough
The present invention relates to the isolation of and characterization of a novel lipase inhibitor and its effect on different lipases. The present invention also relates to the use of a lipase...
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7341857 |
Production of beta-hydroxypalmitate methyl esterase from Ideonella sp.0-0013 (FERM BP-08660)
The present invention provides a novel esterase derived from Ideonella sp. 0-0013 strain (FERM BP-08660) having the following properties: (1) function, substrate specificity: hydrolyzes methyl...
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7332318 |
Calcium-independent phospholipases A2, genes thereof and promoter of the same
Novel calcium-independent phospholipases A 2 ; genes encoding the same; an antibody against them; an inherent promoter or a regulator gene which comprises a base sequence occurring in intron and...
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7319029 |
Lipase from Geobacillus sp. strain T1
A biologically pure culture of Geobacillus Strain T1 bacteria isolated from Palm Oil Mill Effluent capable of producing thermostable lipase T1 gene. The production of thermostable lipase T1 gene...
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7319015 |
Methods and compositions for using alveolar macrophage phospholipase A2
The present invention is directed to methods and compositions for improving pulmonary surfactant catabolism. More specifically, the specification describes methods and compositions for making and...
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7314739 |
Lipase variants
The invention relates to a lipase variant which can be prepared by carrying out, on the amino acid sequence of a starting lipase selected from the lipase homologous family I.1 or I.2, at least one...
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7303904 |
Stable gene variants of lipases
The present invention relates to the generation and production of novel thermostable, organic solvent stable and pH tolerant lipase gene variants. The invention also relates to methods of selecting...
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7294496 |
Cloned human lysophospholipase
A cloned of a human brain lysophospholipid-specific lysophospholipase enzyme molecule, its potential use for treatment of a host of diseases and method of inactivation are disclosed. Also disclosed...
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7288400 |
Nucleic acids encoding esterases and methods of making and using them
The invention relates to esterases and to polynucleotides encoding the esterases. In addition methods of designing new esterase method of use thereof are also provided. The esterases have increased...
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7282233 |
Chemically modified lipolytic enzyme
Lipolytic enzymes are chemically modified by covalently linking one or more (particularly 1-3) hydrophobic groups to the enzyme molecule. The chemical modification improves the performance of the...
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7271139 |
Lipolytic enzyme genes
The inventors have isolated novel lipolytic enzyme genes with a high homology to the T. lanuginosus lipase gene and thus well suited for use in gene shuffling. Accordingly, the invention provides...
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7261888 |
Combined use of triglycerides containing medium chain fatty acids and exogenous lipolytic enzymes as feed supplements
The present invention relates to the use of triglycerides (TG) containing medium chain fatty acids (C4 to C12), combined with exogenous lipolytic enzymes (esterases or lipases) as a feed supplement...
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7247463 |
Enzymes with lipase/acyltransferase activity, nucleic acids encoding the same and methods of use thereof
Polypeptides with lipase/acyltransferase activity are described with an amino acid sequence which has identity to the sequence reported in SEQ ID NO 2 of at least 49%, also polypeptides which...
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7238503 |
Process for making fluoroleucine ethyl esters
The instant invention describes a novel reaction that includes spontaneous racemization of an azalactone via enol tautomerization. This racemization results in improved yield and ee over other...
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7226770 |
Lipolytic enzyme variant
The properties of a fungal lipolytic enzyme can be altered by substituting amino acid residues corresponding to certain specified amino acid residues in the T. lanuginosus lipase. The altered...
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7195888 |
Calcium-independent phospholipase A2 induces ischemic ventricular arrhythmias and decreases infarction size
A method for evaluating a compound to determine the relative or absolute therapeutic capability of a compound to pharmacologically inhibit ischemia induced activation of iPLA 2 β in an intact...
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7176011 |
Lipid cleavage enzyme
A membranous enzyme not yet described in the state-of-the-art can be extracted from cellular membrane fractions of blood leukocytes or monocytes/macrophages. Also disclosed is the use of substrates...
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7172997 |
Lipolytic enzyme variant
The present invention relates to lipolytic enzyme variants with improved thermostability are obtained by substituting certain specified amino acid residues in a fungal lipolytic enzyme. The...
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7157263 |
Lipase variants
Attaching a peptide extension to the C-terminal amino acid of a lipase re-duces the tendency to form odor. This may lead to lipase variants with a reduced odor generation when washing textile...
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7157262 |
Lipolytic enzymes
The present invention relates to a modified enzyme with lipolytic activity, a lipolytic enzyme capable of removing a substantial amount of fatty matter during a one cycle wash, a DNA sequence...
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7091003 |
Polypeptides having phospholipase B activity and nucleic acids encoding same
The present invention relates to isolated polypeptides having phospholipase B activity and isolated nucleic acid sequences encoding the polypeptides. The invention also relates to nucleic acid...
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7087736 |
Tyrosine DNA phosphodiesterases (TDP) and related polypeptides nucleic acids vectors TDP producing host cells antibodies and methods of use
The present invention provides a nucleic acid molecule encoding a tyrosine-DNA phosphodiesterase (TDP), and a related vector, host cell, polypeptide, antibody, antisense nucleic acid molecule, and...
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7087419 |
DNA encoding a plant lipase, transgenic plants and a method for controlling senescence in plants
Regulation of expression of senescence in plants is achieved by integration of a gene or gene fragment encoding senescence-induced lipase into the plant genome in antisense orientation. The...
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7070953 |
Protein hydrolysates produced with the use of cod proteases
The invention relates to a method for enzymatically obtaining protein hydrolysates for human consumption, animal feed and cosmetics. The process involves the use of a proteolytic composition...
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7064196 |
Genes encoding carotenoid compounds
Genes have been isolated from strain DC260, a member of the Enterobacteriaceae family, encoding geranylgeranyl pyrophosphate (GGPP) synthetase (CrtE), phytoene synthase (CrtB), phytoene desaturase...
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7060481 |
Isolated human phospholipase proteins, nucleic acid molecules encoding human phospholipase proteins, and uses thereof
The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the phospholipase peptides of the present invention. The present invention...
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7060474 |
Carbohydrate oxidase and use thereof in baking
The properties of dough or bread can be improved by the addition of a carbohydrate oxidase which can oxidize the reducing end of an oligosaccharide more efficiently than the corresponding...
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7060265 |
Cloning and recombinant production of polistinae venom enzymes, such as phospholipase and hyaluronidase, and immunological therapies based thereon
A unique clone of a Polistinae venom enzyme, recombinantly produced Polistinae venom enzymes, and methods of using the recombinant enzymes are provided. In a specific example, both phospholipase...
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7056720 |
LLG polypeptides of the triacylglycerol lipase family, and compositions and methods for their use in enzymatic hydrolysis, and protein and gene therapies
The present invention relates to LLG polypeptides, which are polypeptides of the triacylglycerol lipase family, and fragments thereof, antibodies against such polypeptides, nucleic acids encoding...
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