|
Match
|
Document |
Document Title |
|
|
6627619 |
Antisense compositions for detecting and inhibiting telomerase reverse transcriptase
The present invention provides TRT antisense oligonucleotides, methods of detecting TRT, methods of diagnosing telomerase-related conditions, methods of diagnosing and providing a prognosis for...
|
|
|
6620596 |
Method of preparing a guanosine-group compound
A glyoxal-guanosine-group compound is prepared either by reacting glyoxal-guanine with any one of ribose-1-phosphate and 2-deoxyribose-1-phosphate in the presence of purine nucleoside...
|
|
|
6610843 |
Modified starch from plants, plants synthesizing the same, as well as process for their production
The present invention describes transgenic plant cells and plants which due to a reduced activity of a disproportionating enzyme (D enzyme) synthesize a modified starch. Furthermore, the starch...
|
|
|
6608239 |
Means and methods for enhancing the content of sulfur compounds in plants
Described are recombinant DNA molecules comprising a nucleic acid molecule encoding a protein having serine acetyltransferase (SAT) activity and optionally a nucleic acid molecule encoding a...
|
|
|
6607740 |
Enzyme-mediated modification of fivrin for tissue engineering
The invention provides fibrin-based, biocompatible materials useful in promoting cell growth, wound healing, and tissue regeneration. These materials are provided as part of several cell and tissue...
|
|
|
6608018 |
Polypeptides having branching enzyme activity and nucleic acids encoding same
The present invention relates to isolated polypeptides having branching enzyme activity and isolated nucleic acid sequences encoding the polypeptides. The invention also relates to nucleic acid...
|
|
|
6605428 |
Method for the direct, exponential amplification and sequencing of DNA molecules and its application
A method is described for the direct, exponential amplification and sequencing (“DEXAS”) of a DNA molecule from a complex mixture of nucleic acids, wherein truncated DNA molecules as well as...
|
|
|
6593119 |
Core 2 β-1,6-N-acetylglycosaminyltransferase gene
Novel core 2 β-1,6-N-acetylglycosaminyltransferase nucleic acids, polypeptides encoded by the nucleic acids, and uses of the nucleic acids and polypeptides.
|
|
|
6593118 |
Method for rapidly obtaining crystals with desirable morphologies
The present invention provides a crystallization process wherein a starting temperature is selected such that a desirable crystal morphology (e.g., square) is obtained. A temperature shift is then...
|
|
|
6593462 |
Purified β1,2-xylosyltransferase and uses thereof
The present invention provides a purified, homogeneous plant enzyme that adds a β-1,2-linked xylose to the β-linked mannose on the N-linked oligosaccharides of storage glycoproteins. This...
|
|
|
6586216 |
Deregulation of glutamine PRPP amidotransferase activity
The present invention is directed to a modified amidotransferase. The amino acid sequence of the modified amidotransferase differs from the amino acid sequence of a native E. coli glutamine PRPP...
|
|
|
6582911 |
Candida albicans KRE9 and uses thereof
The present invention to an isolated DNA which codes for a gene essential for cell wall glucan synthesis of Candida albicans , wherein the gene is referred to as CaKRE9, wherein the sequence of...
|
|
|
6576453 |
Thermostable DNA ligase mutants
Ligase detection reaction is utilized to distinguish minority template in the presence of an excess of normal template with a thermostable ligase. This process can be carried out with a mutant...
|
|
|
6569649 |
Compositions and methods for saccharide synthesis
Processes for preparing oligosaccharides, polysaccharides, glycolipids, glycoproteins, and other saccharide compositions are provided which involve the enzyme facilitated transfer of a preselected...
|
|
|
6566111 |
β-fructofuranosidase and gene thereof
A novel β-fructofuranosidase and its gene are disclosed. A polypeptide comprising the amino acid sequence of SEQ ID No. 1 or No. 3 is an enzyme having β-fructofuranosidase activity and high...
|
|
|
6566100 |
Glycosyltransferase gene gtfE from Amycolatopsis oreintalis
The invention provides isolated nucleic acid compounds encoding a glycosyltransferase enzyme of Amycolatopsis orientalis . Also provided are vectors carrying genes that encode said enzyme,...
|
|
|
6562606 |
Methods and compositions for disrupting the epithelial barrier function
A method for disrupting epithelial barrier function in a host in need of the topical administration of a physiologically active substance which comprises applying to the epithelium of the host,...
|
|
|
6559356 |
Nucleic acid molecules which encode proteins having fructosyl transferase activity and methods for producing long-chain inulin
Nucleic acid molecules which encode proteins having fructosyl transferase activity and methods for producing long-chain inulin Nucleic acid molecules are described encoding proteins with the...
|
|
|
6558915 |
Soybean 1-deoxy-D-xylulose 5-phosphae synthase and DNA encoding thereof
This invention relates to an isolated nucleic acid fragment encoding an isopentenyl diphosphate biosynthetic enzyme. The invention also relates to the construction of a chimeric gene encoding all...
|
|
|
6558914 |
Human lysophosphatidic acid acyltransferase
The invention provides a human lysophosphatidic acid acyltranferase (HLPAAT) and polynucleotides which identify and encode HLPAAT. The invention also provides expression vectors, host cells,...
|
|
|
6558935 |
Human transferase proteins
The invention provides human transferase proteins (TRNSFS) and polynucleotides which identify and encode TRNSFS. The invention also provides expression vectors, host cells, antibodies, agonists,...
|
|
|
6555669 |
Human transferase proteins and polynucleotides encoding the same
Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
|
|
|
6555348 |
Enzyme isolated from a Bifidobacterium
The present invention concerns a new β-galactosidase with transgalactosylating activity isolated from Bifidobacterium bifidum and a truncated enzyme where the C-terminal end of the...
|
|
|
6548280 |
Genes encoding sulfate assimilation proteins
This invention relates to an isolated nucleic acid fragment encoding a sulfate assimilation protein. The invention also relates to the construction of a chimeric gene encoding all or a portion of...
|
|
|
6541227 |
Preparation of labeled DNA
A preparation method of labeled DNA and use thereof are disclosed. More specifically, the invention relates to a preparation method of labeled DNA by preparation of a complex triple-stranded DNA...
|
|
|
6541231 |
Method for the integration of foreign DNA into eukaryotic genomes
Compositions and methods for introducing a DNA of interest into a genomic target site are provided. In particular, the methods and compositions involve the use of a combination of target sites for...
|
|
|
6541238 |
Recombinant cellulose synthase
The present invention relates to the compositions and methods associated with the cloning of the catalytic subunit of cellulose synthase responsible for catalyzing cellulose biosynthesis. The...
|
|
|
6538178 |
Increased starch content in plants
Transformed plant cells which have increased'starch content are disclosed. Also disclosed are whole plants comprising plant cells which express CTP/ADPglucose pyrophosphorylase genes.
|
|
|
6539309 |
Crystallizable farnesyl protein transferase compositions, crystals thereby obtained, and methods for use
The present invention relates to compositions and crystals of farnesyl protein transferase and farnesyl protein transferase in complex with substrates and inhibitors. Also disclosed are...
|
|
|
6537780 |
Isolated nucleic acid molecules encoding transferase enzymes
The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the enzyme peptides of the present invention. The present invention specifically...
|
|
|
6537786 |
Genes encoding exopolysaccharide production
Genes have been isolated from a Methylomonas sp encoding elements of the exopolysaccharide biosynthetic pathway. The genes and gene products are the first isolated from an organisms capable of...
|
|
|
6535820 |
Crystalline farnesyl protein transferase compositions and methods for use
The present invention relates to crystalline compositions comprising farnesyl protein transferase-like polypeptides in complex with substrates and inhibitors. Also disclosed are crystallization...
|
|
|
6534284 |
MurD protein and gene of Staphylococcus aureus
This invention provides the murD gene of Staphylococcus aureas. Purified and isolated MurD recombinant proteins are also provided. Nucleic acid sequences which encode functionally active MurD...
|
|
|
6534298 |
Nucleic acids encoding α-1,3 fucosyltransferases and expression systems for making and expressing them
A bacterial α1,3-fucosyltransferase gene and deduced amino acid sequence is provided. The gene is useful for preparing α1,3-fucosyltransferase polypeptide, and active fragment thereof, which can...
|
|
|
6531296 |
Nuclear tyrosine kinase Rak
A nuclear tyrosine kinase called Rak has been identified. This tyrosine kinase is expressed primarily in epithelial cells, and has been found to be a growth inhibiting kinase. Domains of the Rak...
|
|
|
6531303 |
Method of producing geranylgeraniol
The invention provides a biological method of producing geranylgeraniol.
|
|
|
6528633 |
Cyclin-selective ubiquitin carrier polypeptides
Disclosed are novel human and clam ubiquitin carrier polypeptides involved in the ubiquitination of cyclins A and/or B. Also disclosed are inhibitors of such polypeptides, nucleic acids encoding...
|
|
|
6528637 |
Fatty acid synthase mRNA binding protein
Disclosed is a 178 kDa glucose-inducible human fatty acid synthase (FAS) mRNA binding protein which has been purified to homogeneity and its binding element characterized. This large phosphoprotein...
|
|
|
6518029 |
Human hydrolase-like molecules
The invention provides human hydrolase-like molecules (HHLM) and polynucleotides which identify and encode HHLM. The invention also provides expression vectors, host cells, antibodies, agonists,...
|
|
|
6514732 |
Process for preparing baccatin
A process for preparing baccatin and/or baccatin derivatives is described in which 10-deacetylbaccatin or a 10-deacetylbaccatin derivative is reacted in the presence of an isolated enzyme and an...
|
|
|
6509455 |
Recombinant narbonolide polyketide synthase
Recombinant DNA compounds that encode all or a portion of the narbonolide polyketide synthase are used to express recombinant polyketide synthase genes in host cells for the production of...
|
|
|
6506735 |
Optimized antisense oligonucleotides complementary to DNA methyltransferase sequences
The invention provides optimized antisense oligonucleotides complementary to the DNA methyltransferase gene or its RNA transcript. The invention further provides methods for using such antisense...
|
|
|
6506587 |
TRF 1 binding protein, methods of use thereof
The present invention discloses a unique vertebrate protein, tankyrase that binds to telomeric repeat binding factor 1 (TRF1). Nucleic acids encoding tankyrases are also disclosed. Methods of...
|
|
|
6506571 |
Human glutathione-S-transferase
The invention provides a human glutathione-S-transferase (HGST) and polynucleotides which identify and encode HGST. The invention also provides expression vectors, host cells, agonists, antibodies...
|
|
|
6503741 |
Polyketide synthase genes from Streptomyces venezuelae
Combinatorial libraries of polyketides can be obtained by suitable manipulation of a host modular polyketide synthase gene cluster such as that which encodes the PKS for picromycin. The...
|
|
|
6503749 |
Yeast strains possessing the interrupted ATF2 gene and their applications
A subject of the invention is a modified yeast strain in which the acetyl-CoA pregnenolone acetyltransferase (APAT) activity is eliminated by altering the gene coding for this activity with...
|
|
|
6500644 |
Method for in vivo production of a mutant library in cells
A method for in vivo production of a library in cells comprising a multitude of mutated genetic elements, wherein an error-prone polymerase is used in each ancestral cell to replicate all or a part...
|
|
|
6492152 |
Core 1 β3-galactosyl transferases and methods of use thereof
Core 1 β3-galactosyl transferases and nucleic acids encoding the core 1 β3-galactosyl transferases are described. The enzymes and the nucleic acids encoding said enzymes have been identified in...
|
|
|
6489541 |
Genetic control of plant hormone levels and plant growth
Plant growth and plant growth habit can be controlled without the application of exogenous plant hormones or hormone mimetics using the nucleic acid sequences and methods provided. UDP-Glucose:...
|
|
|
6485935 |
Structure of the ankyrin binding domain of a α-Na, K-ATPase
The present invention provides a polypeptide of 26 amino acid residues that comprises the minimal ankyrin binding (MAB) domain. The MAB domain is responsible for the interactions between a...
|