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8975042 Fluorescent and colored proteins and methods for using them  
The field of this invention relates to methods for combining genetic elements such that the activity of one of the elements provides a means for identifying, enriching, selecting for, or enhancing...
8906640 Methods of measuring protein and/or fat digestibility and uses thereof  
The present invention provides methods for continuous measurement of protein and/or triglyceride digestibility during a meal. Stable isotope of 15N-spirulina protein and 2H5-phenylalanine was...
8809009 Methods of diagnosing a disease and methods of monitoring treatment of a disease by quantifying a non-reducing end glycan residual compound and comparing to a second biomarker  
Provided herein are methods of diagnosing or monitoring the treatment of abnormal glycan accumulation or a disorder associated with abnormal glycan accumulation.
8802413 Cytotoxic ribonuclease variants  
This invention relates to altered forms of members of the RNase A superfamily. An RNase A can be modified to be cytotoxic by altering its amino acid sequence so that it is not bound easily by the...
8795979 Hydrolase enzyme substrates and uses thereof  
The present invention provides novel methods for determining the presence or amount of a hydrolytic enzyme in a sample, based on novel substrates for the enzymes, and also provides compositions...
8795980 Methods for determination of previous ethanol consumption  
An improved method for assessing previous ethanol exposure comprises the steps of obtaining a sample from the body of a subject; quantitatively determining the level of one or several...
8771974 Methods of determining the presence and/or amount of a biomarker to determine the presence, identity, and/or severity of a lysosomal storage or neurological disorder  
Provided herein are methods of diagnosing or monitoring the treatment of abnormal glycan accumulation or a disorder associated with abnormal glycan accumulation.
8748159 Method and apparatus for viable and nonviable prokaryotic and eukaryotic cell quantitation  
A rapid method for the quantitation of various live cell types is described. This new cell fluorescence method correlates with other methods of enumerating cells such as the standard plate count,...
8741597 Reaction medium for methicillin-resistant Staphylococcus aureus  
A reaction medium for detecting and/or identifying Staphylococcus aureus bacteria, comprising a combination of two enzymatic substrates for alpha-glucosidase.
8709741 Methods of diagnosing a plasmodium infection  
The present disclosure provides in vitro methods of diagnosing a Plasmodium infection in a subject. The methods include measuring the serum concentration of at least one secreted phospholipase A2...
8709774 Sperm factor sequences  
A nucleic acid sequence, including an isolated, purified or recombinant nucleic acid sequence, includes: (a) a nucleic acid sequence encoding a polypeptide encompassed by the present invention,...
8703437 Fluorogenic sensors for phospholipase C isozymes  
The present invention provides fluorogenic substrates and methods of use in detecting and analyzing phospholipase C isozyme (PLC) activity.
8696567 Assay for positioning a feeding tube and method thereof  
The present invention discloses a bedside or point of care assay for properly positioning a feeding tube in the stomach of a patient based on detecting the presence of a hydrolytic enzyme found in...
8673609 Buttiauxella sp. phytase variants  
Provided herein are variants of Buttiauxella sp. phytases that may be used in industrial applications including methods for starch liquefaction, alcohol fermentations and for enhancing phosphate...
8663963 Hafnia phytase  
The present invention relates to isolated polypeptides having phytase activity and isolated polynucleotides encoding the polypeptides. The polypeptides are related to a phytase derived from Hafnia...
8658391 Assessment of the effects of topical administration of chemodenervating pharmaceuticals  
The present invention provides methods for assessing the activity of topically administered chemodenervating agents. In some embodiments, methods for assessing the activity of topically...
8658409 Polypeptides having acetyl xylan esterase activity and polynucleotides encoding same  
The present invention relates to isolated polypeptides having acetyl xylan esterase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid...
8628935 PON1 as a marker for heart failure  
Provided herein are methods for assessing the risk a test subject with heart failure has of experiencing a major adverse cardiac event, requiring revascularization, requiring a heart transplant,...
8609357 Methods for detecting LP-PLA2 activity and inhibition of LP-PLA2 activity  
This invention relates to methods for determining the activity of Lp-PLA2 in at least one sample from an animal. The invention also relates to methods for determining the inhibition of Lp-PLA2...
8592173 Cancer diagnosis by measuring polyisoprenylated methylated protein methyl esterase activity  
Methods for cancer diagnosis, making decisions on appropriate cancer treatment, awareness of a predisposition to cancer and potential cancer prevention, and monitoring of cancer therapy by...
8580549 Esterases for separating plastics  
The invention relates to agents containing esterases, and to the use thereof for dressing fibres, in particular, artificial fibres, washing and cleaning agents comprising esterases and...
8563317 Apparatus for detecting gamma hydroxybutyrate, ketamines and related drugs in beverages  
Apparatus for detecting the presence of foreign substances in a beverage. The apparatus for detecting the presence of Gamma-hydroxybutyrate or other drugs in a beverage comprises apparatus wherein...
8563262 Permanent inactivation of nucleases  
The present invention relates to the use of reagent for permanently inactivating nucleases wherein the reagent comprises an oxidizing agent, a protein denaturant and optionally a pH adjustor and...
8524480 Cytotoxic ribonuclease variants  
This invention relates to altered forms of members of the RNase A superfamily. An RNase A can be modified to be cytotoxic by altering its amino acid sequence so that it is not bound easily by the...
8512971 Compounds and methods of use thereof for assaying lysophospholipase D activity  
Fluorogenic lysophosphatidic acid derivatives which can be used as substrates in a continuous, fluorogenic assay that can be performed in microtiter plates. The assays permit measuring LysoPLD...
8501430 Determination of biological material ingredients  
The invention relates to a method for analysing ingredients, in particular lipids and/or vitamins and biological material ingredients, to methods of using relevant organic solvents or organic...
8501426 Method for identifying protease inhibitors  
The invention describes a method for assaying HCV NS3 protease activity using an NS3•4A protease molecule. The invention also provides a method for screening and identifying modulators of NS3...
8497086 Reaction medium for methicillin-resistant Staphylococcus aureus (MRSA) bacteria  
A reaction medium for detecting and/or identifying methicillin-resistant Staphylococcus aureus (MRSA) bacteria includes a chromogenic substrate, a first antibiotic that belongs to the...
8450096 Polypeptides having phytase activity and polynucleotides encoding same  
The invention relates to Citrobacter phytases derived from Citrobacter amalonaticus, Citrobacter gillenii, and related phytases. The phytases belong to the acid histidine phosphatase family, are...
8435964 Ectonucleotidase pyrophosphate/phosphodiestrase-1 (ENPP-1) as a target for the treatment of aortic valve stenosis and cardiovascular calcification  
Aortic valve stenosis (AS) is a chronic process related to a progressive mineralization of the aortic root and valve cusps. We found in human AS valves a high level of expression and enzymatic...
8420345 Method for identifying at least two groups of microorganisms  
The present invention relates to a method for identifying at least two groups of microorganisms expressing the same enzymatic activity, comprising the following steps: a) incubating said groups of...
8361774 Recombinant type II restriction endonuclease, NmeAIII, and a process for producing the same  
A protein is described that has an amino acid sequence characterized by at least 90% sequence identity with SEQ ID NO: 24, the protein being capable of recognizing a sequence consisting of...
8318449 Method of measuring the activity of lipid-modified enzyme  
It is intended to provide an assay method whereby the activity of a lipid-modifying enzyme can be conveniently measured over a wide range and a drug capable of controlling a lipid-modifying enzyme...
8304223 Isoforms of pig liver esterase  
The invention relates to novel mutants of γPLE, to vehicles containing the same and to their use in the production of enantiomer-enriched alcohols, carboxylic acids and esters.
8293537 Systems and methods for hemoglobin analysis  
At least one embodiment of a stabilizing system includes a stabilizing agent present in an amount or concentration sufficient to completely or substantially prevent or reduce degradation or...
8288117 Dry analytical element for lipase measurement  
It is an object of the present invention to provide: a dry analytical element for analyzing pancreatic lipase wherein the triglyceride is not transcribed on the support to contaminate a...
8278085 RNA processing protein complexes and uses thereof  
The invention provides human protein complexes with endonuclease activity, including tRNA splicing endonuclease activity and 3′ end pre-mRNA endonuclease activity, and pre-ribosomal RNA cleavage...
8278063 Methods for degrading toxic compounds  
The invention relates to bacteria, bacterial extracts, supernatants obtained from the culturing of said bacteria, polypeptides and compositions for degrading benzimidazole carbamate fungicides,...
8247190 Method for delivering cytotoxic activity to cells  
This invention relates to altered forms of members of the RNase A superfamily. An RNase A can be modified to be cytotoxic by altering its amino acid sequence so that it is not bound easily by the...
8216799 Dry analytical element for lipase measurement  
It is an object of the present invention to provide a dry analytical element for pancreatic lipase analysis having high selectivity with respect to pancreatic lipase, whose multianalyte...
8198038 Plasma biomarker tool for the diagnosis of liver cancer comprising liver carboxylesterase 1 and liver cancer screening method  
The present invention relates to a plasma biomarker for diagnosing hepatocellular carcinoma (HCC), in particular to the discovery of a protein in plasma using 2-D fluorescence differential gel...
8187832 Method of detecting an amount of a cholinesterase inhibitor in a sample  
A method of detecting an amount of a cholinesterase inhibitor in a sample comprising steps of: (a) contacting the sample with an agent capable of recovering the cholinesterase inhibitor from the...
8178311 Multiple quantification of cholesterol in low density lipoprotein  
The present invention is intended to provide a method for simultaneously measuring cholesterol in low density lipoprotein and total cholesterol as test components in blood. Specifically, a method...
8168406 Dry analytical element for lipase measurement  
The present invention provides a method for producing a dry analytical element for measurement of pancreatic lipase contained in a body fluid which contains triglyceride of long chain alkyl fatty...
8163529 Nicking endonuclease methods and compositions  
A nicking endonuclease is described which has an amino acid sequence with at least 70% identity to SEQ ID NO:6 and comprising a mutation at least one of an arginine or glutamic acid corresponding...
8143045 Mutant Citrobacter freundii phytase polypeptide  
The present invention relates to enzymes and processes. In particular, there is described an isolated polypeptide comprising the amino acid sequence corresponding to Citrobacter freundii phytase...
8119360 Method, reagent and kit for determination of cholesterol in remnant-like particles (RLP)  
The present invention provides a method, a reagent and a kit for simple and sensitive determination of cholesterol in remnant-like particles without separation of components of a sample. A method...
8101376 Swatch for testing the washing performance of an enzyme  
The present invention relates to a swatch comprising a pH-indicator substance and a substrate for an enzyme for testing the washing performance of the enzyme, e.g. an enzyme for use in detergent...
8076115 Polypeptides having phytase activity and polynucleotides encoding same  
The invention relates to Citrobacter phytases derived from Citrobacter amalonaticus, Citrobacter gillenii, and related phytases. The phytases belong to the acid histidine phosphatase family, are...
8071326 Method and apparatus for viable and nonviable prokaryotic and eukaryotic cell quantitation  
A rapid method for the quantitation of various live cell types is described. This new cell fluorescence method correlates with other methods of enumerating cells such as the standard plate count,...