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7238506 |
Electron transport proteins
The invention provides human electron transport proteins (NHETP) and polynucleotides which identify and encode NHETP. The invention also provides expression vectors, host cells, agonists,...
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7232673 |
Antimicrobial protein from Lyophyllum shimeji
The object of the present invention is to screen and identify a novel antimicrobial protein which can inhibit the growth of plant pathogenic microorganisms at a relatively low concentration such as...
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7232672 |
P450 enzymes, nucleic acids encoding them and methods of making and using them
The invention is directed to polypeptides having P450 activity, polynucleotides encoding the polypeptides, antibodies that bind to these polypeptides, and methods for making and using these...
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RE39696 |
Human cyclooxygenase-2 cDNA and assays for evaluating cyclooxygenase-2 activity
The invention discloses a human cyclooxygenase-2 cDNA, a human cyclooxygenase-2 and assays for preferentially and independently measuring cyclogenase-2 or cyclooxygenase-1 activity present in a...
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7226767 |
Process for producing cytidine diphosphate choline
A substantially pure culture of a microorganism having enzyme activities of pyrG and CCT and carrying a recombinant DNA composed of a DNA fragment containing genes encoding pryG and CCT and a vector.
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7226768 |
Cytochrome P450 oxygenases
Nucleic acids encoding cytochrome P450 variants are provided. The cytochrome P450 variants of have a higher alkane-oxidation capability, alkene-oxidation capability, and/or a higher organic-solvent...
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7226769 |
Dual oxidases as mitogenic and endocrine regulators
The present invention relates to new genes encoding for the production of novel proteins involved in generation of reactive oxygen intermediates and in peroxidative reactions that affect biological...
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7226762 |
Gene coding for glucose-6-phosphate-dehydrogenase proteins
The present invention relates to isolated nucleic acid molecules encoding mutants of glucose-6-phosphate dehydrogenase, and vectors and hosts cells including such nucleic acid molecules. These...
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7223578 |
Canine COX-1 nucleic acid molecules and fragments thereof
The present invention relates to canine COX-1 and COX-2 proteins; to canine COX-1 and COX-2 nucleic acid molecules, including those that encode such COX-1 and COX-2 proteins, respectively; to...
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7220571 |
Escherichia coli strains which over-produce L-threonine and processes for the production of L-threonine by fermentation
The present invention relates to the fields of microbiology and microbial genetics. More specifically, the invention relates to novel bacterial strains and processes employing these strains for the...
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7220563 |
Glucose 6-oxidases
Glucose oxidase enzymes are provided, including novel variants of galactose oxidase enzymes. The polynucleotides that encode these novel variants can be expressed in recombinant host cell...
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7220897 |
Δ4-desaturase genes and uses thereof
The subject invention relates to the identification of genes involved in the desaturation of polyunsaturated fatty acids at carbon 4 (i.e., “Δ4-desaturase”). In particular, Δ4-desaturase may...
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7217810 |
High level production of arbutin in green plants and microbes
This invention relates to methods and materials to produce hydroquinone glucoside in genetically modified green plants and microorganisms.
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7217544 |
Method for the preparation of L-amino acids from D-amino acids
The invention relates to recombinant microorganisms which, in comparison to the starting organism, have a higher concentration or activity of a D-amino acid oxidase, of an L-amino acid...
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7214527 |
Compositions and methods for hydroxylating epothilones
Isolated nucleic acid sequences and polypeptides encoded thereby for epothilone B hydroxylase and mutants and variants thereof and a ferredoxin located downstream from the epothilone B hydroxylase...
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7214520 |
Cloning, sequencing and expression of a comamonas cyclopentanone 1,2-monooxygenase-encoding gene in Escherichia coli
Cyclopentanone 1,2-monooxygenase (CPMO) from Comamonas (previously Pseudomonas ) sp. strain NCIMB 9872 carries out the second step of a degradation pathway that allows the bacterium to use...
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7211281 |
Method for improving the activity of enzymes
A method for improving the performance of enzymes used in animal feeds by the use of surfactants. Lecithin and/or lysolecithin is added to an animal feed including an exogenous enzyme to boost the...
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7211249 |
Heat-generating composition for topical application to skin
The present invention provides a method of sustaining the rate of heat felt on the skin as a result of an exothermic reaction between a combination of an unencapsulated and an encapsulated...
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7211420 |
Process for oxidizing terpenes
A process for oxidizing a substrate which is an acyclic or cyclic terpene, or a cycloalkene; or a substituted derivative thereof, which process comprises oxidizing said compound with a mutant...
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7211421 |
Gene encoding dihydrodipicolinate reductase from Bacillus methanolicus
An Escherichia coli mutant strain deficient in dihydrodipicolinate synthase or dihydrodipicolinate reductase is transformed with a chromosomal gene library of Bacillus methanolicus, and a...
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7208301 |
Method for producing 6-0-α-D-glucopyranosyl-D-sorbitol
This invention concerns a method for enzymatic preparation of 6-O-α-D-glucopyranosyl-D-sorbitol (1,6-GPS) from isomaltulose. It is specified that the isomaltulose is put into an aqueous reaction...
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7202035 |
Genetic markers for skatole metabolism
Novel metabolites and enzymes involved in skatole metabolism are disclosed. The novel metabolites are 3-OH-3-methylindolenine (HMI); 3-methyloxindole (3MOI); indole-3-carbinol (I-3C); and...
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7202068 |
Enone reductase and methods of making and using thereof
An isolated enone reductase characterized by a molecular mass of 61300+/−5000 Da; NADPH and NADPH as co-factor; a temperature optimum of 55–60° C. at pH 7.4; a pH optimum of 4.5–8.5 and...
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7198928 |
Human COX-1 alternatively spliced variants and methods of using same
The invention provides an isolated polypeptide containing the amino acid sequence of SEQ ID NO: 14, 16, 18, 20, 22 or 24. The invention also provides an isolated polypeptide containing a) an amino...
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7198947 |
Production of functional proteins: balance of shear stress and gravity
The present invention provides a method for production of functional proteins including hormones by renal cells in a three dimensional co-culture process responsive to shear stress using a rotating...
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7198932 |
Gdp-4-keto-6-deoxy-d-mannose-3,5-epimerase-4-reductase gene derived from arabidopsis thaliana
The present invention relates to a gene for an enzyme involving in the synthesis of GDP-L-fucose. Particularly, the present invention relates to a GDP-4-keto-6-deoxy-D-mannose-3,...
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7195900 |
Cloning and expression of D-amino acid oxidase from arthrobacter protophormiae
The present invention is directed to a nucleotide sequence encoding D-amino oxidase (D-AAO, EC 1.4.3.3) from Arthrobacter protophormiae. This may be inserted into an expression and used to...
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7195889 |
Process for stabilizing enzymes with phosphine or phosphite compounds
The invention relates to processes for stabilizing the activity of an enzyme, comprising mixing a phosphine or phosphite with an oxidoreductase enzyme.
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7192754 |
Nomuraeae rileyi-origin ecdysteroid 22-oxidase and molt hormone inactivation system with the use of the same
A material and a system are provided that efficiently inactivate a molting hormone by means of a protein having ecdysteroid 22-oxidase activity.
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7189545 |
Production and use of pyruvate decarboxylase
A polypeptide with pyruvate decarboxylase activity, derived from the pyruvate decarboxylase from Zymomonas mobilis by substitution of an amino acid in position 553.
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7186511 |
Oxidase
There is disclosed an oxidase gene useful for the diagnosis of RA and the screening of a substance for the treatment of RA and/or a substance for the treatment of osteoarthritis. Also, an...
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7186531 |
L-threonine producing bacterium belonging to the genus Escherichia and method for producing L-threonine
There is disclosed a method for producing L-threonine using bacterium belonging to the genus Escherichia wherein the bacterium has been modified to enhance an activity of...
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7183092 |
Modified luciferase
The invention comprises modified luciferase proteins which are more resistant to inhibition by test chemicals than wild type luciferase. The modified luciferases also contain greater...
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7183091 |
Sulfite reductase, the process for producing the same and the use thereof
The present invention relates to a purified sulfite reductase which has the following characteristics:
a. It functions to catalyze the reduction of sulfites to sulfides or to recover the...
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7183090 |
Laccase enzyme and the gene encoding the enzyme
The invention relates to a new laccase enzyme, which can be isolated from the strains of the Melanocarpus genus, the M. albomyces strain in particular. The pH optimum of the enzyme is within...
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7179615 |
Method of prophylaxis and treatment
The present invention relates generally to a method for the prophylaxis and treatment of parasitic infections in animals and birds. More particularly, the present invention contemplates a method...
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7179627 |
Cyclooxygenase variants and methods of use
The invention relates to the isolation of novel cyclooxygenase type 1 (COX-1) variant enzymes. More specifically, the invention relates to the identification of cyclooxygenase transcripts harboring...
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7179626 |
11-Arachidonate-lipoxygenase mutants
A method for producing a plant lipoxygenase (LOX) with modified positional specificity toward arachidonic acid and its use for hydroperoxylation of arachidonic acid. The LOX makes it possible to...
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7176353 |
Genes encoding sulfate assimilation proteins
This invention relates to an isolated nucleic acid fragment encoding a sulfate assimilation protein. The invention also relates to the construction of a chimeric gene encoding all or a portion of...
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7172894 |
Reductase gene and use of the same
A gene containing a DNA having the nucleotide sequence encoding any one of the amino acid sequences of the following (a) to (e):
(a) an amino acid sequence set out in SEQ ID NO: 1; (b) an...
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7172886 |
Biosynthesis of isopentenyl pyrophosphate
Methods for synthesizing isopentenyl pyrophosphate are provided. A first method comprises introducing into a host microorganism a plurality of heterologous nucleic acid sequences, each coding for a...
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7169580 |
Protein having PGE2 synthase activity and use thereof
A single protein which is the substance of the PGE2 synthesis activity in brain soluble fractions of LPS administered rats has been purified and identified. The protein has an activity of...
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7169589 |
Silicatein-mediated synthesis of amorphous silicates and siloxanes and use thereof
Silicatein is an enzyme of silicate-forming organisms used for the synthesis of their silicate scaffold. The present invention relates to the use of highly-expressed and highly active recombinant...
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7169591 |
Preparation of enantio-specific epoxides
A method for converting alkenes into epoxides and, particularly, to convert alkenes into enantio-specific epoxides by the use of enzymes which may be in their naturally-occuring (native) form or in...
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7166452 |
Aminoketone asymmetric reductase and nucleic acid thereof
A protein, which is an aminoketone asymmetric reductase, having an effect of producing d-pseudoephedrine by acting on 1-2-methylaminopropiophenone, and having the following physiochemical...
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7163814 |
Modified reductase and its gene, and use thereof
There is provided a reductase characterized by
(i) an amino acid sequence of SEQ ID NO:1 having a substitution at amino acid position 54 or 104 or at both of the amino acid positions 54 and...
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7160709 |
Phenol oxidizing enzymes
Disclosed herein are novel phenol oxidizing enzymes naturally-produced by strains of the species Stachybotrys which possess a pH optima in the alkaline range and which are useful in modifying the...
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7160690 |
Nitrate sensor
A biosensor method and apparatus for detecting and measuring nitrate. The biosensor is based on the fluorescence properties of a receptor molecule fragment. The biosensor apparatus contains the...
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7160708 |
Fatty alcohol oxidase genes and proteins from Candida tropicalis and methods relating thereto
The present invention provides fatty alcohol oxidase (FAO) proteins and nucleic acid molecules encoding the FAO proteins. Also provided are analogs, derivatives, and enzymatically active fragments...
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7153666 |
Methods and compositions for determination of glycated proteins
This invention relates generally to the field of glycated protein detection. In particular, the invention provides chimeric proteins, nucleic acids encoding the chimeric proteins, methods and kits...
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