|
Match
|
Document |
Document Title |
|
|
7091018 |
Enzyme gene and its expression product
The present invention is drawn to a gene comprising a polynucleotide encoding a polypeptide composed of an amino acid sequence represented by SEQ ID NO: 1; a gene expression product produced...
|
|
|
7091015 |
Fibrinogen-based tissue adhesive
The present invention provides a fibrinogen-based tissue adhesive which contains an elastase inhibitor.
|
|
|
7091040 |
P450/acetaminophen genetically directed enzyme prodrug therapy (GDEPT)
The invention hereindescribed relates to a form of cancer therapy which exploits the cytotoxic properties of acetaminophen when converted to NABQI by the metabolic activity of tumour cell specific...
|
|
|
7087813 |
Plant lipoxygenases
This invention relates to isolated nucleic acid fragments encoding lipoxygenases. The invention also relates to the construction of recombinant DNA constructs encoding all or a portion of the...
|
|
|
7087427 |
Mammalian alpha-kinase proteins, nucleic acids and diagnostic and therapeutic uses thereof
The present invention provides novel mammalian alpha-kinase proteins: melanoma alpha-kinase (MK), heart alpha-kinase (HK), kidney alpha-kinase (KK), skeletal muscle alpha-kinase (SK), and...
|
|
|
7087417 |
tRNA synthetases, metRS
The invention relates to metRS polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques. Also disclosed are methods for utilizing metRS polypeptides...
|
|
|
7087403 |
Biological production of tetradehydrolycopene
Mutant phytoene desaturase genes are provided encoding polypeptides having the ability to convert a phytoene desaturase substrate to tetradehydrolycopene. Both in vivo and in vitro methods are...
|
|
|
7087814 |
Genes encoding sulfate assimilation proteins
This invention relates to an isolated nucleic acid fragment encoding a sulfate assimilation protein. The invention also relates to the construction of a chimeric gene encoding all or a portion of...
|
|
|
7083961 |
Crystal structures of T. foetus inosine monophosphate dehydrogenase in complex with substrate, cofactor and analogs and uses thereof
The invention provides a crystalline complex containing T. foetus IMPDH in complex with inosine monophosphate (IMP), the complex specified by disclosed atomic coordinates. Also provided are...
|
|
|
7083953 |
Method for the production of p-Hydrozybenzoate in species of Pseudomonas and Agrobacterium
Bacterial strains transformed with the pcu genes are useful for the production of para-hydroxybenzoate (PHBA). Applicant has provided the p-cresol utilizing (pcu) and tmoX gene sequences from ...
|
|
|
7083938 |
Cell-based screening methods
Cell-based screening methods for determining kinase activity are provided. The methods utilize existing cellular pathways that are regulated by kinases. In one embodiment, various components of a...
|
|
|
7083964 |
Method for purifying enzymes from clostridium histolyticum using multi-stage chromatography
The invention relates to a method for purifying at least one enzyme obtained in an excess fermentation of Clostridium histolyticum. It is provided for that the enzymes of the excess...
|
|
|
7083958 |
Membrane scaffold proteins
Membrane proteins are difficult to express in recombinant form, purify, and characterize, at least in part due to their hydrophobic or partially hydrophobic properties. The membrane scaffold...
|
|
|
7078377 |
Compositions and methods for treatment of staphylococcal infection while suppressing formation of antibiotic-resistant strains
Co-administration of a lysostaphin or other anti-staphylococcal agent which cleaves cross-links of peptidoglycans of staphylococci cell walls such as lysostaphin and an antibiotic effective against...
|
|
|
7078203 |
Isolated DNA encoding cullin regulators ROC1 and ROC2, isolated proteins encoded by the same, and methods utilizing the same
The present invention provides isolated polynucleotide sequences encoding the proteins ROC1 and ROC2, the isolated proteins themselves, expression vectors containing at least a fragment of the ROC1...
|
|
|
7078036 |
Modulation of cholesteryl ester transfer protein (CETP) activity
This invention relates to peptides comprising a helper T cell epitope portion and a B cell epitope portion for eliciting an immune response against endogenous cholesteryl ester transfer protein...
|
|
|
7074604 |
Bioproduction of astaxanthin using mutant carotenoid ketolase and carotenoid hydroxylase genes
Protein engineered nucleic acid fragments encoding a CrtO ketolase and a CrtZ hydroxylase are provided with increased astaxanthin synthesis activity. Methods using the present nucleic acid...
|
|
|
7074605 |
α-N-acetylgalactosaminidase from Clostridium perfringens
An isolated and purified α-N-acetyl-D-galactosaminidase from Clostridium perfringens and homologs thereof are disclosed. A method for purifying and isolating the α-N-acetylgalactosaminidase...
|
|
|
7074571 |
Serine carboxypeptidase hx (SCPhx) and compositions thereof
The invention concerns GENSET polynucleotides and polypeptides. Such GENSET products may be used as reagents in forensic analyses, as chromosome markers, as tissue/cell/organelle-specific markers,...
|
|
|
7074587 |
Astaxanthin synthase
The present invention is directed to genetic materials useful for the preparation of astaxanthin from beta-carotene, such as polypeptides having astaxanthin synthase activity, DNA fragments coding...
|
|
|
7070952 |
Genes encoding carotenoid compounds
Genes have been isolated from Pectobacterium cypripedii encoding geranylgeranyl pyrophosphate (GGPP) synthase (CrtE), phytoene synthase (CrtB), phytoene desaturase (Crtl), lycopene cyclase...
|
|
|
7071382 |
Inhibitors of apoptosis proteins in plants
This invention relates to an isolated nucleic acid fragment encoding an apoptosis inhibitory protein. The invention also relates to the construction of a chimeric gene encoding all or a portion of...
|
|
|
7071381 |
Plant vitamin e biosynthetic enzymes
This invention relates to an isolated nucleic acid fragment encoding a vitamin E biosynthetic enzyme. The invention also relates to the construction of a chimeric gene encoding all or a portion of...
|
|
|
7070953 |
Protein hydrolysates produced with the use of cod proteases
The invention relates to a method for enzymatically obtaining protein hydrolysates for human consumption, animal feed and cosmetics. The process involves the use of a proteolytic composition...
|
|
|
7067288 |
Nucleotide sequences which code for the mdhA gene
The invention provides nucleotide sequences from coryneform bacteria which code for maltate dehydrogenase and a process for the fermentative preparation of amino acids using bacteria in which the...
|
|
|
7067297 |
Mannosyltransferase polypeptides and polynucleotides encoding them and methods for making and using them
A DNA encoding a novel protein SMAP-1 having a signal sequence was successfully isolated by screening a cDNA library derived from human fetal hepatocyte using the TMT method developed originally by...
|
|
|
7067296 |
Methods and means for modulating PGE synthase activity
Isolated PGE synthase, provided from encoding nucleic acid. Methods of production and use. Assays for modulators, especially inhibitors, of PGE synthase activity.
|
|
|
7067136 |
Method of screening anti-mycobacterial molecules
This invention relates to a novel mycobacterial protein named DES, which appears to share significant amino acid sequence homology with soluble stearoyl-ACP desaturases. The results of allelic...
|
|
|
7063970 |
Enzymatic preservation of water based paints
A preserved and/or conserved water based paint composition comprising an oxidoreductase, an oxidizing agent, a binder and at least 10% w/w water.
|
|
|
7063971 |
Phosphodiesterase enzymes
Amino acid sequences and nucleotide sequences relating to PDEXV are described. In a preferred aspect, the amino acid sequence comprises the sequence presented as SEQ ID NO:1.
|
|
|
7064192 |
High pressure refolding of protein aggregates and inclusion bodies
The present disclosure provides an effective method for the refolding of denatured proteins in solution so that properly folded, biologically active protein in solution is recovered in high yield....
|
|
|
7063955 |
Method for production of asymmetric carotenoids
Genes have been isolated from Rhodococcus and Deinococcus which encode a specific lycopene β-cyclase capable of converting acyclic carotenoids with at least one ψ-end group to the...
|
|
|
7060478 |
Process for preparing lysozyme
A process for preparing lysozyme is provided which is characterized by mixing the egg white or its diluted solution with diatomaceous earth, kaolin, zeolite, or the mixtures thereof, and followed...
|
|
|
7060484 |
Polypeptides and coagulation therapy
Novel polypeptides (NPs) are provided which are capable of protein C activation without significant fibrinogen clotting activity, and vice versa. NPs having enhanced protein C activating properties...
|
|
|
7060436 |
Nucleic acid accessible hybridization sites
The present invention relates to methods and compositions for analyzing nucleic acids, and in particular, methods and compositions for detection and characterization of nucleic acid sequences and...
|
|
|
7060475 |
Polynucleotides encoding polypeptides involved in intermediates metabolism of central metabolic pathway in methylophilus methylotrophus
The present invention provides polypeptides and polynucleotides involved in central intermediates metabolism in Methylophilus methylotrophus and methods of producing amino acids in microorganisms...
|
|
|
7060482 |
Thermostable xylanases
The present invention is directed to thermostable xylanase enzymes are suitable for feed pelleting applications. The novel xylanase enzymes comprise at least 40% of their optimal activity from a pH...
|
|
|
7056717 |
Genes involved in isoprenoid compound production
Genes have been isolated from Methylomonas 16a sp. encoding the isoprenoid biosynthetic pathway. The genes and gene products are the first isolated from a Methylomonas strain that is capable of...
|
|
|
7056517 |
Glucosyltransferase immunogens
Vaccine compositions and immunogenic compositions are described which are glucosyltransferase subunit vaccines for dental caries and which contain at least one peptide which corresponds to a...
|
|
|
7056703 |
Polypeptides having polymerase activity and methods of use thereof
The invention relates to thermostable polymerases that have polymerase activity temperatures in the range from 90° C. up to 113° C., such as those derived from Pyrolobus fumaria , and to...
|
|
|
7056721 |
EGVI endoglucanase and nucleic acids encoding the same
The present invention provides a novel endoglucanase nucleic acid sequence, designated egl6, and the corresponding EGVI amino acid sequence. The invention also provides expression vectors and host...
|
|
|
7056716 |
High fidelity reverse transcriptases and uses thereof
The invention relates to reverse transcriptases which have increased fidelity (or reduced misincorporation rate) and/or terminal deoxynucleotidyl transferase activity. In particular, the invention...
|
|
|
7056711 |
Attenuation of fibroblast proliferation
Highly purified and specific glycosaminoglycan degrading enzymes, chondroitinase B and chondroitinase AC, are used to treat fibroproliferative diseases. The enzymatic removal of chondroitin sulfate...
|
|
|
7056712 |
Treatment of glycogen storage disease type II
Methods of treating glycogen storage disease type II, by administering acid α-glucosidase, are described, as are compositions for use in treatment of glycogen storage disease type II.
|
|
|
7053269 |
Phospholipid:diacylglycerol acyltransferases
This invention relates to an isolated nucleic acid fragment encoding an acyltransferase, more specifically a phospholipid:diacylglycerol acyltransferase. The invention also relates to the...
|
|
|
7052877 |
Thermus brockianus nucleic acid polymerases
The invention provides nucleic acids and polypeptides for nucleic acid polymerases from a thermophilic organism, Thermus brockianus . The invention also provides methods for using these nucleic...
|
|
|
7052847 |
Method for sequencing nucleic acid molecules
The present invention is directed to a method of sequencing a target nucleic acid molecule having a plurality of bases. In its principle, the temporal order of base additions during the...
|
|
|
7052896 |
Lactobacillus rhamnosus polynucleotides, polypeptides and methods for using them
Novel polynucleotides isolated from Lactobacillus rhamnosus , as well as probes and primers, genetic constructs comprising the polynucleotides, biological materials, including plants,...
|
|
|
7052674 |
Prokineticin polypeptides, related compositions and methods
The invention provides isolated polypeptides that stimulate gastrointestinal smooth muscle contraction, including human prokineticin 1 and human prokineticin 2 polypeptides, and functional...
|
|
|
7049115 |
Genes encoding denitrification enzymes
This invention relates to the isolation of nucleic acid fragments from Methylamons sp. that encode enzymes involved in denitrification. The enzymes arc useful in denitrification reactions and for...
|