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7601525 Alginate gel scaffold having a plurality of continuous parallel microtubular copper capillaries  
The present invention provides copper capillary alginate gels stabilized with barium, chitosan, its derivates, or a combination thereof. These stabilized gels are useful as scaffolds for...
7597885 Tissue engineered biomimetic hair follicle graft  
The present invention relates to an improved scaffold which is constructed to mimic the architecture of the native hair follicle. The present invention also relates to the use of specific...
7585499 Method for encapsulation of cellular material using a charged initiator polymer  
Positively-charged initiator polymers having a polymerization initiator group and a cationic portion are provided. The initiator polymers can be used with a polymerizable material for the formation...
7560258 Glass-immobilized, protein-acrylamide copolymer and method of making thereof  
Disclosed are a polyacrylamide-based method of fabricating surface-bound peptide and protein arrays, the arrays themselves, and a method of using the arrays to detect proteins and to measure their...
7547449 Method for treating a bone defect with an organic/inorganic composite  
The subject invention concerns a composite comprising an organic fluid-swellable, fibrous matrix, such as collagen, and a mineral phase, such as calcium carbonate or phosphate mineral phase, for...
7514249 Biomimetic organic/inorganic composites  
The subject invention concerns a composite comprising an organic fluid-swellable, fibrous matrix, such as collagen, and a mineral phase, such as calcium carbonate or phosphate mineral phase, for...
7514248 Process for making organic/inorganic composites  
The subject invention concerns a composite comprising an organic fluid-swellable matrix, such as collagen, and mineral phase, such as calcium carbonate or phosphate mineral phase, for use as a...
7482152 Methods and devices for microencapsulation of cells  
Devices for the microencapsulation of cells include a first chamber for containing a cell-solution suspension. A plate covers one end of the first chamber. The plate has a plurality of apertures. A...
7462471 Porous biodegradable polymeric materials for cell transplantation  
Polymeric materials are used to make a pliable, non-toxic, injectable porous template for vascular ingrowth. The pore size, usually between approximately 100 and 300 microns, allows vascular and...
RE40555 Preparation of agarose coated, solid agarose beads containing secretory cells  
Biological agents such as secretory cells are encapsulated in a hydrophilic gel made of agarose or collagen-agarose and gelatin sponge-agarose combinations. In a preferred embodiment, semi-solid...
7422900 System and method for forming a connective tissue construct  
A system and method are provided for forming a connective tissue construct, such as a tendon construct, in vitro. A substrate is provided with at least two anchors secured thereto in spaced...
7422879 Process for producing porous polymer films  
Porous films are provided which include a blend of a film forming polymer and a non-film forming material, the film having a network of pores or channels throughout the film. The porous polymer...
7422737 Porous freeze-dried hydrocolloid beads containing viable microorganisms for biological control  
The present invention provides cellular solid carriers comprising viable microorganisms capable of controlling plant pathogens. The cellular solid carriers are formed from water-soluble...
7416869 Enzyme delivery systems, application in water based products  
Aqueous enzyme delivery systems as well as aqueous cosmetics and personal care products were provided which comprise at least one stabile enzyme and a polyglycerol containing at least 15 carbons....
7402381 Method of immobilizing molecules onto a solid phase substrate and method of fabricating a biosensor using the method  
Aspects of the invention can provide a method capable of easily realizing immobilization with the optimum density derived from a concentration control and without phase separation in coadsorption...
7378088 Base material for regenerating an air sinus and regeneration method thereof  
The instant invention provides a base material characterized by having a continuous three-dimensional honeycomb structure for regenerating an air sinus. The invention further provides methods for...
7354750 Methods for separating molecules  
The present invention provides compositions and methods for the separation of metals or molecules such as polypeptides, nucleic acids, or endotoxins using a metal-modified solid support. The metals...
7338657 Injectable microspheres for tissue construction  
The present invention relates to injectable compositions comprising biocompatible, hydrophilic, non-toxic and substantially spherical microspheres associated with stem cells useful for tissue...
7332330 Device for maintaining vascularization near an implant  
A device and a method of maintaining vascularization near an implant, especially a bioartificial hemofilter. By associating cells that excrete angiogenic factors with such an implant,...
7323323 Preparation and xenotransplantation of porcine islets  
The invention relates to developments in the treatment of diabetes in mammals. Particularly it relates to a method of preparing a xenotransplantable porcine islet preparation capable upon...
7323190 Cell delivery system comprising a fibrous matrix and cells  
Cell storage and delivery systems and methods for storing and delivering viable cells to a mammal are disclosed. The cell storage and delivery systems include a biodegradable and/or bioabsorbable...
7304016 Compositions for separating molecules  
The present invention provides compositions for the separation of metals or biomolecules such as polypeptides, nucleic acids, or endotoxins using modified solid supports.
7300779 Preparation of a granule containing protein, corn starch and sugar layered on an inert particle  
Granules that include a protein core are described. The protein core includes a protein matrix which includes a protein mixed together with a starch. The protein matrix can be layered over a seed...
7297331 Beads containing restricted cancer cells producing material suppressing cancer cell proliferation  
Compositions of matter are described which contain restricted cancer cells. When so restricted, the cells produce an unexpectedly high amount of material which suppresses cancer cell proliferation....
7273736 Method for preparing an enzyme containing granule  
The invention relates processes for producing enzyme containing granules having an enzyme containing core and a shell coating the core wherein the preparation of the core and application of the...
7256040 Method and apparatus for preparing monolayers of cells  
The invention concerns an apparatus for preparing monolayers of cells. The apparatus comprises a container ( 6 ) for a cryosubstitution system and an insert ( 1 ) for the container, the insert ( 1...
7247462 Coated enzyme-containing catalyst  
An enzymatic catalyst in the granular form which is non-dispersible in water comprising an inner core provided with a coating which coating comprises an enzymatic material characterised in that the...
7247314 Biocompatible material composition adaptable to diverse therapeutic indications  
A biocompatible material genus serves as the foundation for multiple material composition species, each adapted to a specific therapeutic indication.
7244598 Biomolecule arrays  
Array systems that facilitate the simultaneous monitoring of many interactions between biological molecules and the analysis of cellular protein interactions with high throughput. The present...
7244442 Method for making devices using polyhydroxyalkanoate having pyrogen removed  
Polyhydroxyalkanoates (PHAs) from which pyrogen has been removed are provided for use in numerous biomedical applications. PHAs which have been chemically modified to enhance physical and/or...
7229808 Bioreactor  
The present invention relates to a process for producing a bioreactor using viable immobilized biological material and to the bioreactor itself. More particularly, the present invention relates to...
7211249 Heat-generating composition for topical application to skin  
The present invention provides a method of sustaining the rate of heat felt on the skin as a result of an exothermic reaction between a combination of an unencapsulated and an encapsulated...
7192765 Method for producing a nitrification carrier and for removing nitrogen  
Provided are a nitrite-type nitrification carrier and a method for producing the same and a method and an apparatus for removing nitrogen using the same, in which the quantity of organic matter to...
7166451 Immobilization of enzyme on a fibrous matrix  
A multilayer enzyme immobilization process is provided comprising adsorbing a polyethyleneimine (PEI) solution in a fibrous matrix, and adding an enzyme to the fibrous matrix, which comprises a...
7160716 Device for inducing an immune response in cancer therapy  
A device for inducing an immune response in cancer therapy in which isolated living malignant tissue is enclosed in a space formed by a microporous membrane and a holder which is introduced into a...
7153519 Implantable substrate coated with a macromer having free radical polymerizable substituents  
Water soluble macromers are modified by addition of free radical polymerizable groups, such as those containing a carbon-carbon double or triple bond, which can be polymerized under mild conditions...
7128931 Semi-permeable microcapsule with covalently linked layers and method for producing same  
The present invention relates to semi-permeable microcapsules, which exhibit an increased resistance to mechanical stresses as well as an increased resistance to chemical degradation. More...
7118900 Directed assembly of functional heterostructures  
The present invention relates to a systematic process for the creation of functionally organized, spatially patterned assemblies of polymer-microparticle composites including the AC electric...
7112453 Retentate chromatography and protein chip arrays with applications in biology and medicine  
This invention provides methods of retentate chromatography for resolving analytes in a sample. The methods involve adsorbing the analytes to a substrate under a plurality of different selectivity...
7112315 Molecular nanowires from single walled carbon nanotubes  
Unique single walled nanotube compositions and methods for making the composition wherein the nanotubes encloses foreign material capable of forming thread-like material having a solid form at...
7105339 Retentate chromatography and protein chip arrays with applications in biology and medicine  
This invention provides methods of retentate chromatography for resolving analytes in a sample. The methods involve adsorbing the analytes to a substrate under a plurality of different selectivity...
7105337 Method of removing exogenous endocrine-disrupting chemical in water  
Biological treatment for an environmental hormone in water can be efficiently performed by use of a microorganism-immobilized carrier is provided. To biologically remove an environmental hormonal...
7056726 membrane for encapsulation chamber of cells producing at least a biologically active substance and bioartificial organ comprising same  
The invention concerns a semipermeable chamber for encapsulation of cells producing at least a biological substance of interest, characterised in that it consists of a porous polycarbonate...
7041504 Cancer cell-inhibiting culture medium produced by culturing restricted entrapped cancer cells  
Compositions of matter are described which contain restricted cancer cells. When so restricted, the cells produce an unexpectedly high amount of material which suppresses cancer cell proliferation....
7026146 Encapsulation method for maintaining biodecontamination activity  
A method for maintaining the viability and subsequent activity of microorganisms utilized in a variety of environments to promote biodecontamination of surfaces. One application involves the...
7020560 Methods for cell-based combinatorial logic  
A method for cell-based combinatorial logic includes the steps of providing at least one genetically engineered cell, the genetically engineered cell having at least one transcriptional unit. The...
7018820 Method of removing residual enzymes in enzyme microencapsulation  
Disclosed is a method of removing residual enzymes when microencapsulating enzymes, and more particularly, for inactivating enzymes remaining in an uncapsulated form during microencapsulation of...
7008634 Cell growth substrates with tethered cell growth effector molecules  
Described are compositions with tethered growth effector molecules, and methods of using these compositions for growing cells and tissues. Growth effector molecules, including growth factors and...
6960466 Composite membrane containing a cross-linked enzyme matrix for a biosensor  
An electrochemical sensor system and membrane and method thereof for increased accuracy and effective life of electrochemical and enzyme sensors.
6951745 Polyhydroxyalkanoate-containing structure and manufacturing method thereof  
A method for manufacturing polyhydroxyalkanoate-containing structure, at least a part of a base material surface of the structure being coated with polyhydroxyalkanoate, the method comprises the...