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9040273 Adsorption method for immobilizing the biomolecule and the biocatalysis system using the adsorption method thereof  
A simple, highly efficient, and environmentally friendly method of immobilizing macromolecules, particularly the biomolecules, to a solid carrier and thus forming a bioreactor, including the...
9017643 Particles comprising a releasable dopant therein  
A process for making particles comprising a hydrophobic dopant for subsequent release therefrom is disclosed. The process comprises providing an emulsion comprising a hydrophilic phase and a...
9012193 Micro-bubble plate for patterning biological and non-biological materials  
Systems and methods are provided for patterning biological and non-biological material at specific sites on a plate, as well as growing three dimensional structures. Preferred embodiments comprise...
9011895 EB matrix production from animal tissue and its use for tissue repair  
A method of forming and preserving a bioremodelable, biopolymer scaffold material by subjecting animal tissue to chemical and mechanical processing. In addition to skin tissue, another source of...
8992845 Catalyst functionalized buffer sorbent pebbles for rapid separation of carbon dioxide from gas mixtures  
A method for separating CO2 from gas mixtures uses a slurried media impregnated with buffer compounds and coating the solid media with a catalyst or enzyme that promotes the transformation of CO2...
8986713 Medical device capable of being compacted and expanded having anti-thrombin III binding activity  
The present invention relates to immobilized biologically active entities that retain significant biological activity following mechanical manipulation of a substrate material to which the...
8975073 Microfluidic device comprising silk films coupled to form a microchannel  
A microfluidic device includes, in one embodiment, a first silk film coupled to a second silk film with at least one microchannel therebetween.
8969027 Protease assay  
The present invention provides a diagnostic reagent or assay for assessing the activity of a protease in vivo or in vitro and methods of detecting the presence of a cancerous or precancerous cell....
8962302 Biological tissue processing substrate for fixing proteins or protein degradation products in tissue for analysis  
A biological tissue processing substrate for fixing proteins in a biological tissue or degradation products of the proteins, the substrate comprising: a porous body that forms a contact surface...
8911629 Dialysate regeneration system for portable human dialysis  
A dialysate regeneration chamber is provided. In one embodiment, the dialysate regeneration chamber may include a toxin trap configured to selectively trap toxins and repel select cations. In...
8911986 Coatings containing polymer modified enzyme for stable self-cleaning of organic stains  
Temporary active coatings that are stabilized against inactivation by weathering are provided including a base associated with a chemically modified enzyme, and, optionally a first polyoxyethylene...
8911980 Method for producing lipase powder compositions  
The present invention provides a method for producing a ground product of a lipase powder composition comprising an immobilized lipase in which a lipase derived from Thermomyces sp. is immobilized...
8906686 Method for preparation of implantable constructs  
Neo-cartilage constructs suitable for implantation into a joint cartilage lesion in situ and a method for repair and restoration of function of injured, traumatized, aged or diseased cartilage....
8900842 Method of storing and/or transporting in vitro cell cultures  
The invention relates to a method of storing and/or transporting in vitro two-dimensional cell cultures. The inventive method comprises the following steps consisting in: a) coating a cell culture...
8900843 Kit and method for the capture of tumor cells  
The invention relates to a kit and method for the capture of tumor cells in a body fluid sample. The kit and method of the invention can capture living tumor cells but not non-living tumor cells...
8895046 Orthopaedic implant for supporting tissue growth and methods of forming the implant and tissue  
Adult autologous stem cells cultured on a porous, three-dimensional tissue scaffold-implant for bone regeneration by the use of a hyaluronan and/or dexamethasone to accelerate bone healing alone...
8883441 Method for detecting and counting micro-organisms in a sample  
A method for detecting and counting the microorganisms in a sample is described. The method comprises: a) selectively enriching the microorganism sought in the sample,b) inducing or activating at...
8871457 Method for immobilizing glucose oxidase on a self-assembled monolayer  
Provided are a method for increasing an amount of glucose oxidase to be immobilized on the self-assembled monolayer and a sensor which comprises glucose oxidase immobilized with the method. The...
8858981 Bone healing material comprising matrix carrying bone-forming cells  
A bone healing combination material includes a matrix carrying cultivated bone-forming cells which may be osteocytes, osteoblasts, stromal stem cells or stem cells committed to differentiation...
8845879 Organelle bioelectrodes and methods of making and using the same  
A method for monitoring the metabolic state of an organelle in the presence of a potential organelle modulating agent is disclosed. A first organelle-modified bioelectrode is provided that is...
8846361 Solid phytase compositions stabilized with corn steep liquor  
The present invention relates to solid enzyme, in particular phytase, compositions stabilized with a lactic acid source such as Corn Steep Liquor (CSL), and methods of producing the same....
8841105 Organic-inorganic composite material and process for producing same  
Disclosed is an organic-inorganic composite material obtained by chemically modifying a microorganism-derived ceramic material with an organic group, and a process for producing the...
8834864 Methods for repairing and regenerating human dura mater  
A method of using a substantially non-porous equine collagen foil to repair and regenerate dura mater tissue of mammals when the dura mater tissue is damaged as a result of injury, tumors,...
8835143 Method for preparing hybrid cross-linked enzyme-silica aggregates  
The invention relates to a method for the preparation of hybrid cross-linked enzyme-silica aggregates including the steps of taking up enzyme molecules in a solvent, precipitating the enzyme...
8822190 Polymicrobial formulations for enhancing plant productivity  
The present invention relates to eco-friendly compositions and methods for providing plant growth enhancing formulations comprising mixtures of microbial isolates. In particular, numerous...
8796009 Clearcoat containing thermolysin-like protease from Bacillus stearothermophilus for cleaning of insect body stains  
A substrate or coating is provided that includes a protease with enzymatic activity toward a component of a biological stain. Also provided is a process for facilitating the removal of a...
8785167 Biocompatible article for the treatment of water and production of energy  
A biocompatible article including (a) a biocompatible hydrogel; (b) an adhesive coating on at least a portion of the hydrogel; and (c) one or more organisms adhered to at least a portion of the...
8778376 Copolymer comprising elastin pentapeptide block and hydrophilic block, and medical device and method of treating  
A copolymer comprising a block of an elastin pentapeptide and method of making and using the copolymer are provided.
8759056 Method for producing granules containing fungi of the moniliales family  
A process for the production of granules or pellets containing filamentous fungi is described comprising the steps of selecting and growing filamentous fungi in a suitable culture medium for a...
8753856 Stable biocatalysts of penicillin acylase as gel aggregates and the process of manufacture thereof  
The present invention provides a stable and viable biocatalyst with high activity and operational stability and method of immobilization thereof. The immobilization process is based on the...
8735117 Method for making artificial scaffold having porous three-dimensional body comprising cells  
In on aspect, the invention includes a microcarrier bead having a porous three-dimensional core having (a) a polymeric porous three-dimensional body having porosity of about 15 to about 90% such...
8728769 Xylanases, nucleic acids encoding them and methods for making and using them  
The invention relates to xylanases and to polynucleotides encoding the xylanases. In addition, methods of designing new xylanases and methods of use thereof are also provided. The xylanases have...
8715983 Hudrogel network comprising thermally gelling polysaccharide or protein gel encapsulating living cells  
The present invention is directed to a hydrogel network comprised of a physically cross-linked polymer and a chemically cross-linked polymer or physically entangled copolymer containing living...
8709771 Processing biomass  
Biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) is processed to produce useful products, such as fuels. For example, systems can use feedstock materials, such as...
8709717 Generation of uniform fragments of nucleic acids using patterned substrates  
Methods of generating nucleic acid fragments of substantially uniform length from sample nucleic acids comprising linearly stretching the sample nucleic acids over a substrate having a plurality...
8703122 Method for directed cell in-growth and controlled tissue regeneration in spinal surgery  
The present invention relates to a method for directed cell in-growth and controlled tissue regeneration to prevent post-surgical or post-traumatic adhesion and fibrosis formation on the injured...
8703442 Continuous process for substrate modification using a packed bed column of immobilized enzyme  
A process for the modification of a substrate comprising passing the substrate through a packed bed column of a specific volume of immobilized enzyme wherein the substrate enters the column at or...
8697111 Osteochondral implant comprising osseous phase and chondral phase  
An osteochondral plug includes a first scaffold and a second scaffold. The first scaffold may be a solid scaffold containing one or more pendant reactive functional groups. The second scaffold...
8685426 Methods for making biocompatible, implantable, substantially sericin free silk fabric  
Silk is purified to eliminate immunogenic components (particularly sericin) and is used to form fabric that is used to form tissue-supporting prosthetic devices for implantation. The fabrics can...
8679806 Methods for detecting and/or quantifying a concentration of specific bacterial molecules using bacterial biosensors  
A real-time method employing a portable peptide-containing potentiometric biosensor, can directly detect and/or quantify bacterial spores. Two peptides for specific recognition of B. subtilis and...
8679809 Cell-matrix microspheres, methods for preparation and applications  
A method has been developed to produce stable cell-matrix microspheres with up to 100% encapsulation efficiency and high cell viability, using matrix or biomaterial systems with poor shape and...
8673294 Immunoisolation patch system for cellular transplantation  
An immunoisolation patch system, and particularly a patch system comprising multiple immunoisolation microcapsules, each encapsulating biological material such as cells for transplantation, which...
8669086 Cell and biofactor printable biopapers  
Disclosed herein is a structure having: a porous polymeric film permeated by a first extracellular matrix material; and a topcoat layer comprising a second extracellular matrix gel disposed on the...
8663967 Arginine deiminase mutant and preparation and application thereof  
The present invention relates to an arginine deiminase mutant with partial lysine-deficient and preparation and application thereof. The arginine deiminase mutant of the present invention has...
8652849 Method for separating a substance from a fluid  
This invention relates to a composite material that comprises a support member that has a plurality of pores extending through the support member and, located in the pores of the support member,...
8633027 Knitted biodegradable silk fabric comprising yarn promoting ingrowth of cells and methods of making  
Silk is purified to eliminate immunogenic components (particularly sericin) and is used to form fabric that is used to form tissue-supporting prosthetic devices for implantation. The fabrics can...
8628791 Method of forming an implantable knitted fabric comprising silk fibroin fibers  
Silk is purified to eliminate immunogenic components (particularly sericin) and is used to form fabric that is used to form tissue-supporting prosthetic devices for implantation. The fabrics can...
8623398 Method for generating connective tissue by implanting a biodegradable silk fabric  
Silk is purified to eliminate immunogenic components (particularly sericin) and is used to form fabric that is used to form tissue-supporting prosthetic devices for implantation. The fabrics can...
8614078 Contaminant reducing amide functionalized ordered mesoporous carbon composition  
The present invention is directed to compositions and methods related to delivering degradative enzymes to remove/remedy environmental pollutants. The inventive material comprises a series of...
8603819 Compositions and methods for generating musculoskeletal tissue  
The present disclosure provides compositions comprising musculoskeletal cells and mesenchymal stem cells in discrete regions. The present disclosure provides systems comprising a subject...