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7417021 Biologically active conjugate of a biopolymer and therapeutic agent  
A biologically active conjugate is disclosed comprising a biopolymer and a therapeutic agent joined by a disulfide bond. The conjugate, when formulated in a pharmaceutical composition with a...
7410791 Device containing cytophilic islands that adhere cells separated by cytophobic regions  
The invention provides a device for adhering cells in a specific and predetermined position, and associated methods. The device includes a plate defining a surface and a plurality of cytophilic...
7402381 Method of immobilizing molecules onto a solid phase substrate and method of fabricating a biosensor using the method  
Aspects of the invention can provide a method capable of easily realizing immobilization with the optimum density derived from a concentration control and without phase separation in coadsorption...
7398161 Sampling method and sampling device, and logD measuring method and logD measuring system  
A sampling method sampling a lower-layer liquid from a liquid body comprised of two layers of liquids, an upper-layer liquid (octanol) and the lower-layer liquid (buffer solution), without mixing...
7390784 Administering bifunctional molecules containing a drug moiety and presenter protein ligand for therapy  
Bifunctional molecules and methods for their use in the production of binary complexes in a host are provided. The bifunctional molecule is a conjugate of a drug moiety and a presenter protein...
7371830 Method for separating biological material from a fluid using magnetic particles  
Magnetic particles are prepared containing a magnetic core coated with a glass layer having a substantially pore-free glass surface or having pores with a diameter of less than 10 nm. The particles...
7371400 Multilayer device for tissue engineering  
The invention provides for translating two-dimensional microfabrication technology into the third dimension. Two-dimensional templates are fabricated using high-resolution molding processes. These...
7364899 Device for monitoring haptotaxis  
The present invention discloses a device for monitoring haptotaxis including a housing defining a chamber. The chamber comprises: a first well region including at least one first well, the first...
7364884 Method for producing a hydroxylation catalyst and the use thereof  
A process for preparing a hydroxylation catalyst by i) embedding a cystochrome P450 monooxygenase in a sol-gel matrix, ii) embedding an enzymatic NADPH-regenerating system in a sol-gel...
7361369 Implant with structure allowing injection of polymer for attaching implant to tissue  
Methods and apparatus for bone implants that allow for the directed application of an osteogenic compound. The implant is preferably constructed of a biodegradable polymer formed into a structure...
7354733 Method for sorting and separating living cells  
We disclose methods of sorting or separating mixtures of living cells (e.g., eukaryotic, prokaryotic, mammalian, pathogenic, bacterial, viral, etc.). We perform our methods by activating...
7354702 Processing tissue to produce a biopolymer scaffold for tissue engineering  
A method of forming and preserving a bioremodelable, biopolymer scaffold material by subjecting animal tissue, particularly fetal or neo-natal tissue, to chemical and mechanical processing. The...
7341738 Lipid-encapsulated polyanionic nucleic acid  
Methods for the preparation of a lipid-nucleic acid composition are provided. According to the methods, a mixture of lipids containing a protonatable or deprotonatable lipid, for example an amino...
7335400 Irreversible immobilization of enzymes into polyurethane coatings  
A method of irreversibly immobilizing an enzyme in a polyurethane and an enzyme-containing polyurethane having a degree of immobilization of the enzyme of approximately 100%. The synthesis of...
7335383 Generation of nitric oxide in vivo from nitrite, nitrate or nitrosothiols endogenous in blood  
A material includes a surface and a reactive agent that is located at the surface of the material, covalently attached to a backbone of the material, and/or located within the material. The...
7316919 Composite materials comprising supported porous gels  
This invention relates to a composite material that comprises a support member that has a plurality of pores extending through the support member and, located in the pores of the support member,...
RE39941 Amelioration of Dupuytren's disease  
The cords of Dupuytren's disease are injected with collagenase, the hand is immediately immobilized and maintained immobile for several hours. The cord becomes relaxed or ruptured, relieving the...
7306934 Porous solid ion exchange wafer for immobilizing biomolecules  
A porous solid ion exchange wafer having a combination of a biomolecule capture-resin and an ion-exchange resin forming a charged capture resin within said wafer. Also disclosed is a porous solid...
7297510 Compositions containing enzymes bound to cationic copolymers  
Disclosed are a method of adhering active enzymes to an inert support, the product produced thereby, and a method of using the enzyme-coated support in enzyme-catalyzed reactions such as the...
7297331 Beads containing restricted cancer cells producing material suppressing cancer cell proliferation  
Compositions of matter are described which contain restricted cancer cells. When so restricted, the cells produce an unexpectedly high amount of material which suppresses cancer cell proliferation....
7288394 Selective deposition of materials on countoured surfaces  
A method of patterning materials, such as proteins, on a contoured surface by depositing them onto protrusions on a surface, and a cell containment device that may be constructed by this method,...
7285412 Device for magnetic immobilization of cells  
The present invention relates to an apparatus and methods that immobilize one or more cells associated with magnetic material on a substrate on which are located one or more magnetic receptacle(s)....
7276232 Formulation of microorganisms for use in bait gels for rodent control  
The present invention relates to compositions containing different stages of pathogenic protozoans in a gel and to their use for controlling rodents.
7267938 Patterning of surfaces utilizing microfluidic stamps including three-dimensionally arrayed channel networks  
The present invention describes improved microfluidic systems and procedures for fabricating improved microfluidic systems, which contain one or more levels of microfluidic channels. The methods...
7262281 Method of depositing S-layer proteins on a carrier to immobilize functional molecules  
On a carrier surface, a layer of S-layer proteins is produced as a carrier of functional molecules. A solution containing S-layer proteins in the form of monomers or oligomers is brought into...
7258980 Determining non-nucleic acid molecule binding to target by competition with nucleic acid ligands  
A competitive binding assay is used to determine whether a non-nucleic acid molecule from a library of non-nucleic acid molecules binds to a target. The non-nucleic acid molecule competes with a...
7252981 Method for the preparation of stable and reusable biosensing granules  
The present invention provides a process for the preparation of stable and reusable biosensing granules useful in the assessment of biodegradability of effluents. The biosensing granules are...
7247481 Process for culturing cells sampled for biopsy  
The present invention provide: a novel process for culturing animal cells and a kit for culturing animal cells, in which, even if the number of cells as sampled for biopsy is extremely small, the...
7244598 Biomolecule arrays  
Array systems that facilitate the simultaneous monitoring of many interactions between biological molecules and the analysis of cellular protein interactions with high throughput. The present...
7238505 Immobilized DNA polymerase  
The present invention relates to a DNA polymerase immobilized by covalent bonding. More particularly, the present invention relates to an immobilized DNA polymerase whose activity is maximally...
7220562 Preparation of (E)- and (Z)-2-methyl-2-butenoic acids  
A method has been developed to prepare (E)- and (Z)-2-methyl-2-butenoic acids (2M2BA) from a mixture of (E,Z)-2-methyl-2-butenenitriles (2M2BN) by the regioselective hydrolysis of (E)-2M2BN to...
7198926 Preparation of (E)- and (Z)-2-methyl-2-butenoic acids  
A method has been developed to prepare (E)- and (Z)-2-methyl-2-butenoic acids (2M2BA) from a mixture of (E,Z)-2-methyl-2-butenenitriles (2M2BN) by the regioselective hydrolysis of (E)-2M2BN to...
7195899 Cell-based biosensor for harmful airborne agents  
A method of monitoring an air atmosphere for a harmful biological or chemical agent includes providing a plurality of mammalian respiratory airway epithelial cells borne on a porous support;...
7192766 Sensor containing molded solidified protein  
A method for formulating and immobilizing a protein and a protein matrix formed by the method. The protein matrix preparation method results in a physically and chemically stable protein matrix...
7183073 Method for detecting microorganisms  
A device and method are provided for isolating and culturing microorganisms from a bulk fluid sample. The device comprises a container having therein a polymeric immobilization layer having...
7182943 Method and system for modulation of microbial cell characteristics  
A method and a system is disclosed for the modulation of various characteristics of probiotic cells and for the production of probiotics having altered characteristics. Such altered characteristics...
7169892 Lipid-peptide-polymer conjugates for long blood circulation and tumor specific drug delivery systems  
The present invention relates to conjugates of a lipid, substrate peptide of an enzyme secreted from the cells of mammals, including humans, and a water-soluble polymer that can be used as...
7157258 Particles containing coated living micro-organisms, and method for producing same  
Particles containing dehydrated living micro-organisms are coated with a homogeneous layer of hydrophobic substance selected to reduce the risks of degradation of the micro-organisms by...
7128904 Material containing metal ion ligand complex producing nitric oxide in contact with blood  
Biocompatible materials that have the ability to release nitric oxide (NO) in situ at the surface-blood interface when in contact with blood. The materials which may be polymers (e.g.,...
7122356 Method for attachment of biomolecules to medical device surfaces  
A method for making a medical device having at least one biomolecule immobilized on a substrate surface is provided. One method of the present invention includes immobilizing a biomolecule...
7112453 Retentate chromatography and protein chip arrays with applications in biology and medicine  
This invention provides methods of retentate chromatography for resolving analytes in a sample. The methods involve adsorbing the analytes to a substrate under a plurality of different selectivity...
7109022 Composition containing calcium carbonate particles dispersed in sulfur for removing nitrate nitrogen  
This invention relates to a denitrifying composition which is a material to be used for decomposing nitrates nitrogen in effluent by sulfur-oxidizing bacteria that consume sulfur and carbonate as...
7105339 Retentate chromatography and protein chip arrays with applications in biology and medicine  
This invention provides methods of retentate chromatography for resolving analytes in a sample. The methods involve adsorbing the analytes to a substrate under a plurality of different selectivity...
7101544 Cholesterol-lowering agents, secondary bile acid production inhibitors, and foods and drinks  
Secondary bile acid production inhibitors and cholesterol-lowering agents containing a yeast as the active ingredient.
7087658 Water-soluble coating agents bearing initiator groups  
A method of forming a polymer layer on a support surface by the use of a coating agent and polymerizable compounds. The coating agent provides photoreactive groups adapted to attach the agent to...
7083936 Aminodextran compositions and conjugates and method of making and using them  
A composition containing polydisperse aminodextran polymer molecules is soluble in an aqueous solution at a concentration of 10 mg/ml. The molecules therein have a narrow size distribution...
RE39172 Method for preparing two-layer bicomposite collagen material for preventing post-operative adhesions  
A bicomposite material based on collagen is prepared which has two closely bound layers and is biocompatible, non-toxic, hemostatic and biodegradable in less than a month, and can be used in...
7074903 Monoclonal antibody specific to tartrate-resistant acid phosphatase 5b and use thereof  
Monocolonal antibodies having a higher reactivity with tartrate-resistant acid phosphatase 5b (TRACP 5b) than tartrate-resistant acid phosphatase 5a (TRACP 5a) and having a higher specificity to...
7070941 Methods and compositions for tagging via azido substrates  
The invention provides methods and compositions for azide tagging of biomolecules. In one embodiment of the invention, proteins are tagged by metabolic incorporation of prenylated azido-analog...
7067306 Device containing cytophilic islands that adhere cells separated by cytophobic regions  
The invention provides a device for adhering cells in a specific and predetermined position, and associated methods. The device includes a plate defining a surface and a plurality of cytophilic...
Matches 1 - 50 out of 964 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 >