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7625730 |
Method for classifying and counting leukocytes
There is provided a method for classifying and counting leukocytes with abnormal DNA amount, which comprises:
(1) a step of staining cells in a sample obtained from a hematological sample by...
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7611614 |
Method of cell capture
Embodiments of methods and devices are disclosed for the manipulation (e.g., concentration, purification, capture, trapping, location, transfer) of analytes, e.g., biomolecules, with respect to...
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7582443 |
Method for the detection and measurement of Hapten-conjugated biological binding entities by western and dot-blot using anti-hapten antibodies
The invention is a procedure for measuring the binding of an entity (ligand) to a surface by using a hapten-conjugated version of the ligand (hapten-ligand). An excess of the hapten-ligand is...
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7569373 |
Method for counting megakaryocytes
A method for counting megakaryocytes in a specimen is described. In the method, first, erythrocytes in the specimen are lysed and nucleic acid in the megakaryocytes is stained with a fluorescent...
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7527924 |
Method and apparatus for viable and nonviable prokaryotic and eukaryotic cell quantitation
A rapid method for the quantitation of various live cell types is described. The method may include a variety of steps including: 1) suspending the cells in a detergent-like compound, 2) isolating...
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7521187 |
Method for freeze-drying nucleic acid/block copolymer/cationic surfactant complexes
This invention relates generally to the freeze-drying of formulations comprising a polynucleotide, a block copolymer and a cationic surfactant. In the presence of a cryoprotectant or bulking agent,...
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7476313 |
Apparatus for mixing magnetic particles
An apparatus and method for carrying out the affinity separation of a target substance from a liquid test medium by mixing magnetic particles having surface immobilized ligand or receptor within...
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7439048 |
Apparatus for acoustic ejection of circumscribed volumes from a fluid
This invention is directed to the use of focused energy, particularly focused acoustic energy, in the spatially directed ejection of circumscribed volumes of a fluid which differ in acoustic...
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7399609 |
Staphylococcus detection
The invention relates to methods of detecting staphylococcus.
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7384559 |
Device and method for treating magnetic particles
A device for treating magnetizable or magnetically attractable particles which are present in a liquid, comprising a holder for one ore more reaction vessel(s) with the liquid containing the...
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7371830 |
Method for separating biological material from a fluid using magnetic particles
Magnetic particles are prepared containing a magnetic core coated with a glass layer having a substantially pore-free glass surface or having pores with a diameter of less than 10 nm. The particles...
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7354733 |
Method for sorting and separating living cells
We disclose methods of sorting or separating mixtures of living cells (e.g., eukaryotic, prokaryotic, mammalian, pathogenic, bacterial, viral, etc.). We perform our methods by activating...
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7351558 |
Solventless extraction process
The present invention provides a method for extracting lipids from microorganisms without using organic solvent as an extraction solvent. In particular, the present invention provides a method for...
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7306924 |
Biosensor and related method
A method for collecting a microbiological substance utilizes a micro fabricated biochip having a collection chamber. A fluid sample containing a microbiological entity of interest is delivered to...
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7270986 |
Ejection of localized volumes from fluids
A method is provided for acoustically ejecting from a channel or other container a plurality of fluid droplets, each of which contains one or more particles or other localized volumes. The...
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7157257 |
Method of treating biological cells and/or their cell components with electrical fields
A method is described for treating biological cells and/or their cell components with electrical fields in a reaction medium, in which an inhibitor is added to the reaction medium to counteract the...
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7151000 |
Method of concentrating proteins from serum
A sample is prepared from blood in a manner which makes it possible to further analyze proteins in the sample, e.g. to detect prions in the sample. Blood is extracted, allowed to clot and subjected...
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7135144 |
Method for the manipulation of a fluid sample
The invention provides a device and method for the manipulation of materials (e.g., particles, cells, macromolecules, such as proteins, nucleic acids or other moieties) in a fluid sample. The...
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7125696 |
Method for preparing a polypeptide soluble in an aqueous solvent in the absence of detergent
A invention concerns a novel method for preparing a polypeptide soluble in an aqueous solvent in the absence of detergent, and polypeptides obtainable by said method. The invention also concerns...
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7014744 |
Method of purification and concentration using AC fields with a transfer tip
Embodiments of methods and devices are disclosed for the manipulation (e.g., concentration, purification, capture, trapping, location, transfer, etc.) of analytes, e.g., biomolecules, with respect...
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6989086 |
Channel-less separation of bioparticles on a bioelectronic chip by dielectrophoresis
The present invention comprises devices and methods for performing channel-less separation of cell particles by dielectrophoresis, DC high voltage-pulsed electronic lysis of separated cells,...
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6955924 |
Laminin chains: diagnostic uses
The instant invention provides for the identification, diagnosis, monitoring, and treatment of invasive cells using the laminin 5 gamma-2 chain protein or nucleic acid sequence, or antibodies thereto.
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6930314 |
Light detection device
Apparatus and methods for optical illumination and/or detection with improved flexibility and/or read speed. The apparatus and methods may include mechanisms for selecting and switching between...
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6908766 |
Device and method for capturing biological tissues
A device and method for capturing a biological tissue, comprises cutting a minute biological cellular tissue using a contactless cutting apparatus, wherein, by inverting a biological tissue slide...
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6900029 |
Method of selection of a population or subpopulation of a sample utilizing particles and gravity sedimentation
A separation procedure for separating a selected desired or undesired population from a biological sample utilizing relatively heavy, dense particles and gravity sedimentation. The particles have...
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6887362 |
Dielectrophoretic separation and immunoassay methods on active electronic matrix devices
This invention relates to devices and methods for performing active, multi-step molecular and biological sample preparation and diagnostic analyses employing immunochemical techniques. It relates...
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6870047 |
Magnetic pigment
Magnetic particles are prepared containing a magnetic core coated with a glass layer having a substantially pore-free class surface or having pores with a diameter offices than 10 nm. The particles...
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6849423 |
Focused acoustics for detection and sorting of fluid volumes
A method is provided for acoustically ejecting from a channel or other container a plurality of fluid droplets, each of which contains one or more particles or other localized volumes. The...
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6777214 |
Method for controlling organisms and material therefor, method for selective adsorption of proteins and material therefor, cement material and biomaterial
A method for controlling organisms which comprises growing, decreasing, activating or inactivating cells, bacteria, viruses or fungi at an N-surface or a P-surface of a ceramic which is formed by...
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6773903 |
Laser cell purification system
A process and apparatus for cell purification and ablation is disclosed. The present invention comprises a laser system which directs radiant energy at computer or manually selected individual...
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6767699 |
Method for the quantitation of alphavirus replicon particles
Methods of production and purification for viruses and virus-derived vectors, including those related to alphaviruses, are disclosed. In one aspect, methods of purification that subject alphavirus...
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6660493 |
Hydrodynamic enhanced dielectrophoretic particle trapping
Hydrodynamic enhanced dielectrophoretic particle trapping carried out by introducing a side stream into the main stream to squeeze the fluid containing particles close to the electrodes producing...
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6635181 |
Continuous, hybrid field-gradient device for magnetic colloid based separations
A continuous, hybrid magnetic field gradient device for colloidal magnetic affinity separation having an axially-rotating horizontal glass tube, and a plurality of axially located repeating...
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6630299 |
Fluorescence detection
The present invention provides methods of detecting and/or characterizing the viral vector particle content of a medium. A medium is provided and contacted with an excitation energy such that, if a...
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6602422 |
Micro column system
A separation and release process for purifying biological material on a micro separation column includes release of the biological material from magnetic carriers and elution from the micro...
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6544727 |
Methods and devices for the removal of psoralens from blood products
Methods and devices for the removal of psoralens and psoralen photoproducts from blood products are described. The methods include contacting a psoralen- and irradiation-treated blood product with...
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6531304 |
Method for modifying the dispersion characteristics of metal organic-prestabilized or pre-treated nanometal colloids
The present invention relates to a process for modifying the dispersing properties of organometallic-prestabilized or organometallic-pretreated nanometal colloids by reacting reactive metal-carbon...
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6417011 |
Methods and materials for improved high gradient magnetic separation of biological materials
Improvements in the existing procedures and materials for conduct of high gradient magnetic separation (HGMS) are disclosed. The use of plastic coated matrices especially small spheres or balls...
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6346196 |
Flow-through, hybrid magnetic field gradient, rotating wall device for enhanced colloidal magnetic affinity separations
A slowly rotating separation chamber with an oscillating axial magnetic field gradient created by an alternating current solenoid superimposed on a steady radial gradient in a horizontal chamber is...
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6337215 |
Magnetic particles having two antiparallel ferromagnetic layers and attached affinity recognition molecules
Magnetic particles are prepared and used for selective separation of affinity bound partners in solution. The magnetic particles have large magnetic moments which can be made such that different...
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6287832 |
Method and apparatus for fractionation using generalized dielectrophoresis and field flow fractionation
The present disclosure is directed to a novel apparatus and novel methods for the separation, characterization, and manipulation of matter. In particular, the invention combines the use of...
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6255477 |
Particles having a magnetic core and outer glass layer for separating biological material
Magnetic glass particles are prepared containing a magnetic core coated with a glass layer having a substantially pore-free glass surface. The particles are used for separating biological material...
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6228624 |
Method to select and transfect cell subpopulations
A method for transfecting and separating cells is disclosed. The method comprises preparing magnetic particles coated with genetic material and a cell-specific ligand, and using the particles to...
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6210881 |
Method for reducing inhibitors of nucleic acid hybridization
The present invention relates to a method for reducing the amount of substances inhibitory to nucleic acid hybridization in samples. The method is practiced prior to release of target nucleic acid...
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6184011 |
Method of releasing solid matrix affinity adsorbed particulates
A method of releasing particulates from a solid matrix is provided. The method is effected adding to the solid matrix a degrading enzyme capable of degrading the solid matrix, to thereby release...
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6143510 |
Measuring method using whole blood sample
A method for quantitatively measuring analyte in an undiluted whole blood sample is disclosed which involves contacting an undiluted whole blood sample comprising the analyte with...
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6127151 |
Antigenic preparations and the isolation of such preparations
A method of deriving an antigen from Bordetella pertussis, wherein the antigen is characterized by the following features: a relative molecular weight of about 67,000 to 73,000 as determined by...
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6123860 |
Method for separating cell populations by thermophilic characteristics
The method for removing a thermophilic group of cells from a source of mixed cells, such as blood, comprises the steps of obtaining a sample, testing the sample to determine the temperature...
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6120735 |
Fractional cell sorter
A method and apparatus for the fraction sorting of cells is provided. The invention include a dispensing device, aspirating device, flow channel and a magnetic assembly. A first fractional sorting...
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5985593 |
Compositions and methods for enzymatic decontamination
The present invention is related to a method for the enzymatic decontamination of specimens as a means to control microbiological contamination. The compositions and methods of the invention are...
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