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8065015 |
Regulation of genes via application of specific and selective electrical and electromagnetic signals
Methods and devices for the regulation of gene expression by cells via the application of fields generated by specific and selective electric and electromagnetic signals so as to target diseased or...
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8058042 |
Method and circuit arrangement for treating biomaterial
Disclosed is a circuit arrangement comprising at least one storage device for electrical charges to generate at least one voltage pulse by selectively discharging the storage device, and at least...
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8017369 |
System and method of up-regulating bone morphogenetic proteins (BMP) gene expression in bone cells via the application of fields generated by specific and selective electric and electromagnetic signals
Methods and devices are described for the regulation of bone morphogenetic protein gene expression in bone cells via the application of fields generated by specific and selective electric and...
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7981611 |
Regulation of fibroblastic growth factor-2 (FGF-2) gene expression in living cells with the application of specific and selective electric and electromagnetic fields
Methods and devices are described for the regulation of Fibroblastic Growth Factor-2 mRNA and/or FGF-2 protein in bone cells and other tissues via capacitive coupling or inductive coupling of...
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7923238 |
Multi-channel electroporation system
Systems, methods and apparatus provide flexible and efficient high throughput electroporation systems. An electrical pulse may be transmitted to any number of channels of a multi-channel sample...
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7892799 |
Method for in vivo, ex vivo and in vitro repair and regeneration of cartilage
A method for in vivo, ex vivo and in vitro regeneration of cartilage, collagen and bone remodeling by intermittently applied hydrostatic pressure consisting of repeated periods of applied...
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7754447 |
Methods for producing recombinant proteins
The present invention provides a method for controlling the partitioning of a recombinant protein between the supernatant and the periplasm in E. coli host cell cultures wherein expression of the...
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RE41391 |
Regulation of type II collagen gene expression using specific and selective electrical and electromagnetic signals
Methods and devices for the regulation of type II collagen gene expression in cartilage cells via the application of specific and selective fields generated by specific and selective electric and...
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7732175 |
Method and circuit arrangement for treating biomaterial
The invention relates to a method for treating biomaterial using at least one electrical field generated by a first voltage pulse which is terminated once the value for an electrical parameter has...
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7709260 |
Sealing closure of bacterial ghosts by means of bioaffinity interactions
The invention relates to a method for preparing closed bacterial ghosts by way of specific interactions between partners of a bioaffinity binding pair, and to the bacterial ghosts which can be...
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7572623 |
Cell separation using electric fields
The present invention involves methods and devices which enable discrete objects having a conducting inner core, surrounded by a dielectric membrane to be selectively inactivated by electric fields...
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7560269 |
Real time electronic cell sensing system and applications for cytotoxicity profiling and compound assays
The present invention includes devices, systems, and methods for assaying cells using cell-substrate impedance monitoring. In one aspect, the invention provides cell-substrate impedance monitoring...
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7501232 |
Method for cell selection
The invention relates to a method for the non-invasive selection of single living cells under gentle conditions from mixtures of cells or cell cultures with respect to a specific production...
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7470533 |
Impedance based devices and methods for use in assays
A device for detecting cells and/or molecules on an electrode surface is disclosed. The device detects cells and/or molecules through measurement of impedence changes resulting from the cells...
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7468150 |
Synthesis of conducto-magnetic polymers as nano-transducers in biosensor design
A conductive polymer of polyaniline (PANi), tetracyanoquinodimethane (TCNQ) and a transferrin family member. The conductive polymer can be used in conductometric assays, including biosensor...
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7468263 |
Method for controlling biological function with mechanical vibration and device therefor
Methods and apparatus for controlling biological functions with mechanical vibration are provided. Stimulation is applied to cells of one of an organism, bacteria or virus by mechanical vibration....
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7465566 |
Regulation of genes via application of specific and selective electrical and electromagnetic signals
Methods and devices for the regulation of gene expression by cells via the application of fields generated by specific and selective electric and electromagnetic signals so as to target diseased or...
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7465546 |
Regulation of transforming growth factor-beta (TGF-β) gene expression in living cells via the application of specific and selective electric and electromagnetic fields
Methods and devices are described for the regulation of Transforming Growth actor (TGF)-β1, β2, and/or β3 protein gene expression in bone cells and other tissues via the capacitive coupling or in...
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7429471 |
Regulation of matrix metalloproteinase gene expression using specific and selective electrical and electromagnetic signals
Methods and devices for the regulation of matrix metalloproteinase gene expression in cartilage cells via the application of fields generated by specific and selective electric and electromagnetic...
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7374916 |
Regulation of aggrecan gene expression using specific and selective electrical and electromagnetic signals
Methods and devices for the regulation of aggrecan gene expression in cartilage cells via the application of fields generated by specific and selective electric and electromagnetic signals in the...
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7354748 |
Method for treating osteoarthritis and other diseases, defects and injuries of the knee joint
A method for applying therapeutic electrical signals and/or electromagnetic fields to a patient's knee for the treatment of osteoarthritis and other diseases, defects and injuries. The device that...
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7297522 |
Methods and compositions for treating epilepsy
Compositions comprising a plurality of yeast cells, wherein said plurality of yeast cells have been cultured in the presence of an alternating electric field having a specific frequency and a...
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7259001 |
Methods and compositions for treating male sexual dysfunction
The invention provides compositions comprising a plurality of yeast cells, wherein said plurality of yeast cells are characterized by their ability to increase secretion of male hormones or...
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7125695 |
Directed evolution of microorganisms
The present invention provides methods for directing the evolution of microorganisms comprising the use of mutator genes and growth under conditions of selective pressure. The method discloses...
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7078202 |
Methods and compositions for treating vascular dementia
Compositions comprising a plurality of yeast cells, wherein said plurality of yeast cells have been cultured in the presence of an alternating electric field having a specific frequency and a...
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7022506 |
Method and device for treating osteoarthritis, cartilage disease, defects and injuries in the human knee
A method of determining the voltage and current output required for the application of specific and selective electric and electromagnetic signals to diseased articular cartilage in the treatment...
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6994850 |
Method for preparing a biological fertilizer composition comprising swine manure
The present invention provides a method for preparing a biological fertilizer composition that comprises yeast cells and swine manure. The yeast cells of the invention have an enhanced ability to...
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6977168 |
Methods and compositions for treating nephrotic syndrome
Compositions comprising a plurality of yeast cells, wherein said plurality of yeast cells are characterized by their ability to treat nephrotic syndrome (e.g., lower urinary protein and increase...
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6964864 |
Methods and compositions for treating gastritis
The invention provides compositions comprising a plurality of yeast cells, wherein said plurality of yeast cells are characterized by their ability to ameliorate or prevent gastritis in a mammal,...
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6955886 |
Scintillation proximity assay for the detection of peptidoglycan synthesis
The invention provides a scintillation proximity assay for detecting peptidoglycan synthesis. The assay is especially suitable for high throughput screening of compounds affecting peptidoglycan...
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6951756 |
Closure of bacterial ghost
The invention relates to a method for preparing closed bacterial ghosts by means of vesicle membrane fusion and to the bacterial ghosts which can be obtained in this way. Active compounds, e.g....
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6919205 |
Regulation of type II collagen gene expression using specific and selective electrical and electromagnetic signals
Methods and devices for the regulation of type II collagen gene expression in cartilage cells via the application of specific and selective fields generated by specific and selective electric and...
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6913913 |
Methods and compositions for treating renal failure
Compositions comprising a plurality of yeast cells, wherein said plurality of yeast cells are characterized by their ability to ameliorate renal failure (e.g., improved diuretic effect and/or...
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6913914 |
Methods and compositions for treating hepatitis B
The invention provides compositions comprising a plurality of yeast cells, wherein said plurality of yeast cells are characterized by their ability to normalize the level of serum...
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6855513 |
Quorum sensing signaling in bacteria
The invention provides methods for identifying a modulator of quorum sensing signaling in bacteria, and for identifying a quorum sensing controlled gene in bacteria. In addition, the invention...
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6846667 |
Virulence genes and proteins, and their use
The present invention is based on the identification of a series of virulence genes in E. coli K1, the products of which may be implicated in the pathogenicity of the organisms. The identification...
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6828131 |
Biological fertilizer based on yeasts
The present invention provides biological fertilizer compositions that comprise yeast cells that have an enhanced ability to fix atmospheric nitrogen, decompose phosphorus minerals and compounds,...
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6800466 |
Biological fertilizer compositions comprising sludge
The present invention provides biological fertilizer compositions that comprise yeast cells and sludge. The yeast cells of the invention have an enhanced ability to fix atmospheric nitrogen,...
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6793933 |
Dietary supplements for enhancing the immune system
Compositions comprising a plurality of yeast cells, wherein said plurality of yeast cells are characterized by their ability to enhance the immune system (e.g., increase the activity of T and B...
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6770464 |
Methods for producing poly(hydroxy) fatty acids in bacteria
The present invention relates to a process for the production of poly (hydroxy fatty acids) as well as recombinant bacterial strains for carrying out the process. In addition, new poly(hydroxy...
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6761886 |
Biological fertilizer compositions comprising cattle manure
The present invention provides biological fertilizer compositions that comprise yeast cells and cattle manure. The yeast cells of the invention have an enhanced ability to fix atmospheric nitrogen,...
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6759055 |
Dietary supplements for improving kidney function
Compositions comprising a plurality of yeast cells, wherein said plurality of yeast cells are characterized by their ability to improve kidney functions (e.g., restoring urine secretion and/or...
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6756050 |
Dietary supplements for improving memory
Compositions comprising a plurality of yeast cells, wherein said plurality of yeast cells have been cultured in the presence of an alternating electric field having a specific frequency and a...
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6753008 |
Dietary supplements beneficial for the liver
Compositions comprising a plurality of yeast cells, wherein said plurality of yeast cells are characterized by their ability to normalize the serum level of GPT, AP and/or LDH-5 in a mammal, said...
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6709849 |
Dietary supplements for regulating male hormone
Compositions comprising a plurality of yeast cells, wherein said plurality of yeast cells are characterized by their ability to treat male hormone deficiency in a subject as a result of having been...
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6665429 |
Method and apparatus for microbiological disk recognition
A method and associated apparatus for use in a microbiological assay procedure wherein a plurality of diffusion disks are placed on a nutrient medium on a plate, each of the disks carrying a...
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6635457 |
Selection for more efficient transformation host cells
This invention provides methods for producing and selecting host cells that better survive transformation treatment by subjecting host cells to conditions that alter them, subjecting the altered...
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6596272 |
Biological fertilizer compositions comprising poultry manure
The present invention provides biological fertilizer compositions that comprise yeast cells and poultry manure. The yeast cells of the invention have an enhanced ability to fix atmospheric...
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6596273 |
Biological fertilizer compositions comprising swine manure
The present invention provides biological fertilizer compositions that comprise yeast cells and swine manure. The yeast cells of the invention have an enhanced ability to fix atmospheric nitrogen,...
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6569654 |
Electroactive materials for stimulation of biological activity of stem cells
Compositions, methods and systems are provided for the stimulation of biological activities within stem cells by applying electromagnetic stimulation to an electroactive material, wherein the...
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