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5731008 |
Electrically hydrolyzed salines as microbicides
A microbiocidal solution for in vivo and in vitro treatment of microbial infections contains an electrolyzed saline containing regulated amounts of ozone and active chlorine species wherein the...
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5723324 |
Apparatus and method for electrostatic endothelial cell seeding and DNA transfection in a vascular prosthesis
An apparatus and method are provided for in vitro seeding endothelial cells and transfecting DNA on the luminal wall of a vascular prosthesis. The apparatus has an internal conductor and an...
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5712086 |
Process for transfusing cell containing fractions sterilized with radiation and a quencher of type I and type II photodynamic reactions
A process is presented for transfusing cells which have been sterilized with radiation and a quencher of type I and type II photodynamic reactions. The cells are removed from a donor and exposed to...
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5691190 |
Phaffia rhodozyma mutants, process for producing β-carotene and use of β-carotene rich biomass
The subject of the present invention is Phaffia rhodozyma mutants blocked in the step of conversion of β-carotene in the pathway of biosynthesis of astaxanthin. The present invention also relates...
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5670332 |
Enzymatic reactions and apparatus for carrying them out
A water-supported enzymatic reaction is carried out with the substrate and the enzyme present in the solid phase. Either the water does not form a liquid continuum around substrate and enzyme, or...
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5665762 |
Decontaminating clinical samples
The present invention contemplates methods of decontaminating human fluids prior to processing in the clinical laboratory. The techniques handle large volumes of human serum without impairing the...
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5656450 |
Activation of latent transforming growth factor β by matrix vesicles
A latent growth factor such as transforming growth factor beta (TGFβ) is converted to active form by matrix vesicles or an extract from matrix vesicles. The matrix vesicles may be stimulated with...
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5656468 |
Cells or tissue coated with non-fibrogenic alginate less than 200 μm thick
An electrostatic process is used for coating a biological material with a uniform, continuous polymer layer by discharging a suspension of the biological material in a gelable coating polymer...
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5643742 |
System for electronically monitoring and recording cell cultures
This invention provides an improved system for monitoring and recording cell cultures. A method for measuring a delay period for an alternating current voltage applied across a pair of pins...
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5633129 |
Electrophoretic detection and separation of mutant DNA using replaceable polymer matrices
The disclosure relates to a method for resolving double-stranded DNA species differing by at least one base pair. Each of the species is characterized by an iso-melting domain with a unique melting...
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5632957 |
Molecular biological diagnostic systems including electrodes
A system for performing molecular biological diagnosis, analysis and multi-step and multiplex reactions utilizes a self-addressable, self-assembling microelectronic system for actively carrying out...
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5622848 |
Electrically hydrolyzed salines as microbiocides for in vitro treatment of contaminated fluids containing blood
A microbiocidal solution for in vivo and in vitro treatment of microbial infections includes an electrolyzed saline containing regulated amounts of ozone and active chlorine species wherein the...
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5605662 |
Active programmable electronic devices for molecular biological analysis and diagnostics
A self-addressable, self-assembling microelectronic device is designed and fabricated to actively carry out and control multi-step and multiplex molecular biological reactions in microscopic...
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5597457 |
System and method for forming synthetic protein crystals to determine the conformational structure by crystallography
A method for forming synthetic crystals of proteins in a carrier fluid by use of the dipole moments of protein macromolecules that self-align in the Helmholtz layer adjacent to an electrode. The...
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5573927 |
Antibiotic susceptibility test
This invention relates to a method for biodetection and identification of antibiotic susceptibility tested in bacteria by cerating spectrum against target cells and comparing them.
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5565320 |
Quality control assay for platelet decontamination
A quality control assay to verify adequate treatment of blood product following decontamination with furocoumarins and light. The methods involve measuring the inhibition of template-dependent...
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5558996 |
Fungus extraction method, kit, and extraction solution
A method and kit for extracting fungus from a plant. An extraction solution is combined with tissue from a plant and the combination is agitated, preferably by shaking, to extract a detectable...
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5556958 |
Inactivation of pathogens in clinical samples
The present invention contemplates methods of decontaminating human fluids prior to processing in the clinical laboratory. The techniques handle large volumes of human serum without impairing the...
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5538867 |
Process for the electrochemical regeneration of pyridine cofactors
The present invention relates to a process for the electrochemical regeneration of pyridine cofactors. The process of the invention is characterized by the use, in a reaction medium subjected to...
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5525198 |
Electrorheological crystallization of proteins and other molecules
An electrorheological crystalline mass of a molecule is formed by dispersing the molecule in a dispersion fluid and subjecting the molecule dispersion to a uniform electrical field for a period of...
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5516670 |
Magnetophoretic particle delivery method and apparatus for the treatment of cells
A method of delivering particles into a cellular specimen such that there is minimal disruption or damage to the specimen. In accordance with the method, a monodispersion of tiny acicular...
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5510033 |
Electrokinetic transport of microorganisms in situ for degrading contaminants
The method and apparatus of the present invention feature the use of and electric current to induce movement of bacteria in situ to degrade contaminants in aquifers.
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5482833 |
Test to determine predisposition or susceptibility to DNA associated diseases
Cellular DNA repair enzyme activity has been found to be an indicator of susceptibility or predisposition of an individual to DNA associated diseases. The activity of the enzyme adenosine...
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5459072 |
Food-grade integration vectors for industrial bacterial strains
The present invention is directed to integration vectors including food-grade integration vectors, a method of increasing the stability of the inheritance of genes in microorganisms and transformed...
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5424302 |
Process for the production of starch degradation products with a narrow molecular weight distribution
A process is described for the production of starch degradation products with a narrow molecular weight distribution which is characterized in that a native starch, a starch derivative, a partially...
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5403730 |
Process for the selective deactivation of esterases and catalases in trigonopsis variabilis cells by microwave heating while retaining D-amino acid oxidase activity
Microwave heating of intact Trigonopsis variabilis cells to 60°-68° C. for 20-40 seconds selectively deactivates esterases and catalases while retaining the activity of D-amino acid oxidase. The...
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5372929 |
Methods for measuring the inactivation of pathogens
Methods for measuring pathogen inactivation, and in particular, methods for measuring pathogen inactivation in blood and blood products after photochemical decontamination. The methods involve...
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5350686 |
Microwave acceleration of enzyme-catalyzed modification of macromolecules
A method of enhancing the enzyme-catalyzed modification of macromolecules comprising exposure of the enzyme and its macromolecule substrate to microwaves is disclosed. A frequency of from 1800 to...
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5296963 |
Apparatus and method for applying a laser beam through a microscope
An inverted microscope is adapted so that a specimen thereon e.g. cells can be irradiated by a laser beam. The laser beam is guided from a laser source by a series of adjustably movable reflectors...
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5288605 |
Methods for inactivating bacteria in blood preparations with 8-methoxypsoralen
Methods and compositions are described for treating contaminants in material intended for in vivo use, and in particular blood and blood products for human use. Contaminants in blood cell...
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5250284 |
Method for increasing nuclear magnetic resonance signals in living biological tissue using zinc
A method of enhancing a magnetic resonance signal comprising the steps of administering a quantity of a selected magnetic isotope to a living biological tissue at a concentration greater than the...
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5232844 |
Photodynamic inactivation of viruses in cell-containing compositions
The present invention concerns the product produced by inactivating extracellular lipid enveloped pathogenic virus or intracellular pathogenic virus in a composition containing >1×10 9 ...
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5217888 |
Yeast with high content of arginine
The present invention relates to yeast with a high arginine content which belongs to Kluyveromyces polysporus and has resistance to ethionine.
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5186800 |
Electroporation of prokaryotic cells
Electroporation of prokaryotic cells is achieved by the application of high-intensity electric fields of short duration to reversibly permeabilize the cell walls. Preferably, the field strength of...
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5089385 |
Method of culturing cells in a flow-through cell cultivation system
A flow-through cell cultivation apparatus and method is described. The flow-through cell cultivation system comprises a flowcell, a chamber inside the flowcell for holding cells, and a flowcell...
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5079145 |
Process for preparing microorganisms used for making phenyl acetyl carlinol (PAC)
Mutations are induced in a microorganism selected from the species Saccharomyces cerevisiae or from the species Candia flareri. The resulting mutants are cultured in the presence of a fermentation...
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5028541 |
Flow-through cell cultivation system
A flow-through cell cultivation apparatus and method is described. The flow-through cell cultivation system comprises a flowcell, a chamber inside the flowcell for holding cells, and a flowcell...
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5023172 |
Predictive assay for tumor control
An in vitro method for determining clonogenicity of and measuring the effect of physical (such as radiation or heat) or chemical treatment on mammalian test cells, including normal and tumor test...
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4999284 |
Enzymatically amplified piezoelectric specific binding assay
A quartz crystal microbalance assay in which the binding of analyte to a surface on or near a quartz crystal microbalance (QCM) is detected by a conjugate which comprises an enzyme capable of...
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4983516 |
Bioelectrochemical measurement of microbial activity using a working electrode of carbon-bearing porous material
Microbial activity in an aqueous medium is measured in a bioelectrochemical cell in which the working electrode comprises an electrically conductive carbon-bearing porous material; suitably a...
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4861704 |
Processes for development of acceptance of transplanted organs and tissues
A patient's acceptance of a transplanted organ or tissue from a donor may be enhanced by irradiating donor-specific blood with ultraviolet-B radiation at a dosage of less than 1000 J/M 2 so as to...
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4847198 |
Detection and indentification of bacteria by means of ultra-violet excited resonance Raman spectra
A bacterial suspension is contacted by a single vavelength in the ultra-violet range. A portion of the light energy used is absorbed and a portion of the light energy is emitted. The emitted light...
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4788038 |
Process for killing cells
The present invention relates to a method for killing cells characterized by bringing a material containing living cells into contact with a non-conductor-carrying photosemiconductor material or a...
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4767717 |
Method of detecting and quantitating cell malignancy in biological tissue
A method of detecting and quantitating cell malignancy in biological tissue is provided and initially includes preparing a tissue sample having a substantially constant thickness. The tissue sample...
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4574116 |
Methods and cell lines for immortalization and monoclonal antibody production by antigen-stimulated B-lymphocytes
Methods are provided for producing fusion partners which involve employing an immortalized human myeloma cell line sensitive to HAT and having an additional dominant selectable resistance marker...
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4528265 |
Processes and products involving cell modification
Living mammalian cells are modified by subjecting them to the influence of the ions from a metal electrode, for example of silver, which is placed in contact with them and which is made...
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4395397 |
Apparatus and method for killing unwanted cells
Method and apparatus for removing, from a flowing liquid stream containing a suspension of living cells, a subpopulation of unwanted cells having one or more characteristics distinguishing them...
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4346172 |
Electrochemical process and apparatus to control the chemical state of a material
Electrochemical process and apparatus to control the chemical state of a material, that is, to cause said material to retain desired characteristics in an environment that normally would cause a...
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4327180 |
Method and apparatus for electromagnetic radiation of biological material
Living cells suspensed in a saline buffering media are exposed to microwave radiation without raising the temperature of the cells, to study the non-thermal effects of radiation on the cells, in an...
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4250139 |
Microwave sterilization of dry protein
Method for decontaminating proteinaceous host materials from microorganisms, while retaining chemical, physical and physiological properties of said host proteinaceous materials, said method...
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