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7608191 |
Production of a fermentation product
A process of separating suspended solids from a fermentation liquor by subjecting the liquor to a solids-liquid separation stage, wherein the fermentation liquor is produced in a fermentation...
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7582444 |
Use of flocculating agents for separating the solid residue in hydrolysed fermentation substrates
Process for improving the separation efficiency of residual solid matter from the liquid phase of an aqueous acid hydrolysate of a naturally occurring polysaccharide comprising dissolved sugars,...
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7582215 |
Production of a fermentation product
A process of separating suspended solids from a fermentation liquor by subjecting the liquor to a solids-liquid separation stage, wherein the fermentation liquor is produced in a fermentation...
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7566563 |
Compositions and methods for manipulating carbon flux in cells
Nucleotide sequences and genetic constructs that can be used to regulate genes encoding enzymes that change carbon flux through metabolic pathways that lead to lactic acid or fumarate production in...
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7563606 |
Method for producing non-amino organic acid
Non-amino organic acids such as succinic acid, malic acid and fumaric acid are produced by reacting bacterial cells or treated bacterial cells of a coryneform bacterium with an organic raw material...
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7470530 |
Rumen bacteria variants and process for preparing succinic acid employing the same
Provided are novel rumen bacterial mutants resulted from the disruption of a lactate dehydrogenase gene (ldhA) and a pyruvate formate-lyase gene (pfl) from rumen bacteria; a novel bacterial mutant...
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7455997 |
Production of fermentation product
A process of producing fermentation product comprising the steps of, (i) forming an acidified suspension of particulate plant derived material comprising a first polysaccharide which is more...
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7368268 |
Coryneform bacterium transformant and process for producing dicarboxylic acids using the same
The present invention provides an aerobic coryneform bacterium transformant in which a lactate dehydrogenase gene is disrupted, and a pyruvate carboxylase gene is recombined so as to be highly...
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7262046 |
Aerobic succinate production in bacteria
Methods of increasing yields of succinate using aerobic culture methods and a multi-mutant E. coli strain are provided. Also provided is a mutant strain of E. coli that produces high amounts of...
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7244610 |
Aerobic succinate production in bacteria
Methods of increasing yields of succinate using aerobic culture methods and a multi-mutant E. coli strain are provided. Also provided is a mutant strain of E. coli that produces high amounts of...
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7183086 |
Enzymatic hydrolysis of cyclic oligomers
The present invention relates to a process for enzymatic hydrolysis of cyclic oligomers of poly(ethylene terephthalate), which process comprises subjecting the cyclic oligomer to the action of one...
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7063968 |
Organic acid producing microorganism and process for preparing organic acids employing the same
A novel microorganism capable of producing organic acids, Mannheimia sp. 55E, and a process for producing organic acid through anaerobic and aerobic incubation using the novel microorganism are...
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7022503 |
Process for the stereoselective preparation of functionalized vicinal diols
The present invention relates to a process for the kinetic resolution of racemic functionalized epoxides in the presence of microorganisms, crude or pure preparations thereof comprising a...
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6828115 |
Epoxide hydrolases from streptomyces
A description is given of epoxide hydrolases from bacteria of the genus Streptomyces , a novel process for the enzymatic separation of epoxide enantiomeric mixtures, of a novel detection method...
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6777213 |
Isolation of carboxylic acids from fermentation broth
A process for recovering carboxylic acids from an aqueous mixture such as a fermentation broth using a solvent containing at least one olefin without the need for first removing the spent...
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6743610 |
Method to produce succinic acid from raw hydrolysates
A method for producing succinic acid from industrial-grade hydrolysates is provided, comprising supplying an organism that contains mutations for the genes ptsG, pflB, and ldhA, allowing said...
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6596521 |
Method for manufacturing organic acid by high-efficiency continuous fermentation
The present invention provides a method for manufacturing organic acid by high-efficiency fermentation, which comprises the steps of continuous culture of organic acid bacteria and collection of...
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6590071 |
Reversible aqueous pH sensitive lipidizing reagents, compositions and methods of use
The present invention provides lipidized conjugates comprising an amino group-containing biologically active substance and a lipophilic group capable of penetrating a biological membrane. Under...
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6448061 |
Pta LDHA double mutant Escherichia coli SS373 and the method of producing succinic acid therefrom
This invention relates to a mutant Escherichia coli SS373 and the production of succinic acid by using the above strain. In detail, a novel E. coli SS373 (W3110 pta::Tn10 ldhA::Km) with the...
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6448025 |
Motor proteins and methods for their use
The present invention provides high throughput screening systems for identifying compounds useful in the treatment of cellular proliferation disorders. The method can be performed in plurality...
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6331420 |
Cytochrome P450 monooxygenase and NADPH cytochrome P450 oxidoreductase genes and proteins related to the omega hydroxylase complex of Candida tropicalis and methods relating thereto
Novel genes have been isolated which encode cytochrome P450 and NADPH reductase enzymes of the ω-hydroxylase complex of C. tropicalis 20336. Vectors including these genes, transfected host cells...
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6297032 |
Recombinant cephalosporin C amidohydrolase in cephalosporin biosynthesis
The present invention relates to an enzyme process for the one-step conversion of cephalosporin C or a derivative thereof into 7-aminocephalosporanic acid or a corresponding derivative thereof. The...
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RE37393 |
Mutant E. coli strain with increased succinic acid production
A method for isolating succinic acid producing bacteria is provided comprising increasing the biomass of an organism which lacks the ability to catabolize pyruvate, and then subjecting the biomass...
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6288275 |
Separation and purification of carboxylic acids from fermentation broths
Carboxylic acids, particularly dicarboxylic acids, are separated from a fermentation broth by adjusting the pH of the fermentation broth to about 2.0 or below, and then heating the broth to a...
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6265190 |
Succinic acid production and purification
A highly efficient process for the production and recovery of pure succinic acid from a succinate salt that involves minimal use of additional reagents, and produces virtually no waste by-products,...
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6245538 |
Process for recovering carboxylic acids from a fermentation broth
Carboxylic acids are recovered from a fermentation broth by adjusting the pH of a fermentation broth comprised of a carboxylic acid to at least about 6.0 and then heating the pH-adjusted broth to a...
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6238895 |
Production of aspartic and malic acids with microbacterium
The use of strains of the genus Microbacterium for the production of organic acids or amino acids by the enzymatic conversion of a fumaric acid to the organic acid or amino acid desired, as well as...
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6171831 |
Method for the production of itaconic acid using aspergillus terreus solid state fermentation
The method to produce itaconic acid is a solid-state fermentation method. Sugarcane pressmud or peeled sugarcane pressmud is the support used to adsorb liquid medium for the production of itaconic...
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6159738 |
Method for construction of bacterial strains with increased succinic acid production
A fermentation process for producing succinic acid is provided comprising selecting a bacterial strain that does not produce succinic acid in high yield, disrupting the normal regulation of sugar...
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6004784 |
Fermentation medium and method for producing α, ω -alkanedicarboxylic acids
This invention describes a low cost biofermentation medium, and an economical method using the medium, for the manufacture of α, ω-alkanedicarboxylic acids. The invention provides a...
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5976867 |
Use of serospecific biocarrier compositions for enhanced biodegradation and bioremediation of groundwater
A composition and method for using the composition for degrading pollutants in-situ. The composition comprises a biocarrier coated with an antigen-specific antibody that attracts and binds...
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5962285 |
Process for making polycarboxylic acids
Aliphatic polycarboxylic acids are made by a process comprising the steps of: (1) fermenting a beta-oxidation blocked C. tropicalis cell wherein both copies of the chromosomal POX5 gene and the...
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5962280 |
Microorganisms immobilized on a solid support with a quaternary polyallylamine polymer
Enzyme-containing cells are immobilized on a water-insoluble support with a polymer represented by the following general formula (I): ##STR1## wherein Y is a direct bond or a divalent group...
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5958744 |
Succinic acid production and purification
A highly efficient process for the production and recovery of pure succinic acid from a succinate salt that involves minimal use of additional reagents, and produces virtually no waste by-products,...
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5939296 |
Process for producing L-aspartic acid
A novel enzymatic, non-batch process for converting maleic acid to fumaric acid and/or producing L-aspartic acid, wherein dissolved oxygen concentration in the reaction medium in the reaction...
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5869301 |
Method for the production of dicarboxylic acids
The present invention is an economical fermentation method for the production of carboxylic acids comprising the steps of a) inoculating a medium having a carbon source with a carboxylic...
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5824449 |
Process for producing D-malic acid
A process for producing D-malic acid selectively without producing L-malic acid, using inexpensive maleic acid as a starting material, may be carried out using a microorganism belonging to the...
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5783428 |
Method of producing fumaric acid
Fumaric acid is produced by reacting a culture of a microorganism which produces maleate isomerase that exhibits a maximum activity at not less than 50° C. or a treated product thereof with maleic...
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5766439 |
Production and recovery of organic acids
A process is described for producing organic acids such as lactic acid. The process includes the steps of producing lactic acid by fermentation, resulting in an aqueous fermentation broth...
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5723322 |
Process for making succinic acid, microorganisms for use in the process and methods of obtaining the microorganisms
A fermentation process for making succinic acid in high concentrations employs a bacteria obtained from the rumen contents of cattle. A preferred bacteria is Bacterium 130Z (ATCC No. 55618).
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5667996 |
Process for production of bacterial cells containing poly-3-hydroxy butyric acid
Disclosed is a process for accumulating a poly-3-hydroxy butyric acid in bacterial cells by continuously fermenting a methanol-assimilating bacterium having a capability of producing a...
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5627276 |
Peroxide degradation of DNA for visocity reduction
Peroxide, particularly supplied as hydrogen peroxide, is an effective nucleic acid degrading agent and can be used in the recovery of intracellularly produced materials from cell (particularly...
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5620877 |
Method of fermenting sugars resulting from strong acid hydrolysis
An economically viable method of fermenting a mixture of sugars resulting from the acid hydrolysis of material containing cellulose and hemicellulose allows for the simultaneous fermentation of...
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5573931 |
Method for making succinic acid, bacterial variants for use in the process, and methods for obtaining variants
A method for producing succinic acid in high concentration by fermentation employs a variant of strain 130Z which is resistant to concentrations of about 1 g/l to about 8 g/l of sodium...
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5521075 |
Method for making succinic acid, anaerobiospirillum succiniciproducens variants for use in process and methods for obtaining variants
A method for making succinic acid employs a fluoroacetate resistant variant of Anaerobiospirillum succiniciproducens. The fluoroacetate variant produces a succinic acid product which contains less...
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5508181 |
Process for producing alpha-hydroxy acid or alpha-hydroxyamide by microorganisms
A process for the production of α-hydroxy acids or α-hydroxyamides in which an α-hydroxynitrile compound or a mixture consisting of an aldehyde and prussic acid, which corresponds to the nitrile...
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5326702 |
Biological process for producing α-hydroxyamide or α-hydroxy acid
A process for biologically producing an α-hydroxyamide or an α-hydroxy acid represented by formula (III) ##STR1## wherein R represents a substituted or unsubstituted alkyl group, a substituted or...
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5270190 |
Method for producing (R)-malic acid from maleic acid using microbial maleate hydratase
This invention relates to a method for producing (R)-malic acid comprising contacting, in a reaction medium, maleic acid with (A) a microbial maleate hydratase capable of hydrating maleic acid to...
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5177008 |
Process for manufacturing ethanol and for recovering glycerol, succinic acid, lactic acid, betaine, potassium sulfate, and free flowing distiller's dry grain and solubles or a solid fertilizer therefrom
This invention relates to the manufacture of ethanol and the recovery of economically significant amounts of such by-products therefrom as glycerol, betaine, L-pyroglutamic acid, succinic and...
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5168055 |
Fermentation and purification process for succinic acid
A process for economically producing highly purified succinic acid comprises growing a succinate-producing microorganism on a low cost carbohydrate substrate; simultaneously neutralizing the...
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