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5116757 |
Mevalonic acid-producing microorganism
A mevalonic acid-producing microorganism which belongs to Saccharomycopsis fibuligera and is resistant to ML-236B.
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5108917 |
Process for the preparation of ibuprofen
A process is provided for the preparation of ibuprofen enriched in R isomer, which comprises subjecting an ester of ibuprofen, to the action of a micro-organism or substances derived thereof, that...
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5100789 |
Process for the production of mevalonic acid by a strain of Saccharomycopsis fibuligera
In the production of mevalonic acid by culturing a mevalonic acid-producing microorganism in a medium, at least peptone originating from casein and corn steep liquor are added to the medium. The...
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5089405 |
Process for the preparation of optically active 2-arylpropionic acids and pharmaceutical compositions containing the same
S Enantiomers of 2-arylpropionic acids are made by enantioselective hydrolysis of the corresponding racemic 2-arylpropionamides in the presence of a microorganism, or of an enzyme derived...
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5079153 |
Process for the preparation of organic esters of ascorbic acid or erythorbic acid using ester hydralases in organic solvents containing 100-10,000 ppm of water
A process for the preparation of an organic ester of ascorbic acid or erythorbic acid represented by the general formula (II) or (III): ##STR1## wherein R 1 is alkyl, aralkyl, or aryl, by reacting...
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5075233 |
Process for the preparation of 2-aryloxypropionic acids
A process is provided for the enrichment in R isomer of an aryloxypropioic acid ester and for the stereoselective hydrolysis of an aryloxypropionic acid ester to form the corresponding...
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5071753 |
Process for the enzymatic preparation of organic esters of ascorbic acid or erythorbic acid
A process for the preparation of an organic ester of ascorbic acid or erythorbic acid represented by the general formula (II) or (III): ##STR1## wherein R 1 is alkyl, aralkyl, or aryl, by reacting...
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5071762 |
Enhancing the flavor of protein products derived from microorganisms
The present invention provides a process for the enhancement of the flavor of proteins derived from dried microorganisms comprising a) contacting a fermentation broth containing a suitable...
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5061629 |
Production of 2-hydroxy substituted arylalkanoic acids and esters by enzymatic hydrolysis
Enantiomerically pure (2R)-2-hydroxy arylalkanoic acid esters and (2S)-2-hydroxy arylalkanoic acids are prepared by the Pseudomonas lipase-catalyzed selective hydrolyxis of racemic (2RS)-2-hydroxy...
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5057427 |
Method for resolution of stereoisomers
This invention relates to a novel method of effecting aqueous enzymatic and homogeneous resolutions of racemic esters which exhibit enhanced aqueous solubility. The preferred embodiment of this...
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5043274 |
Process for producing an optically active 2-arylpropionic acid
A process for the preparation of S-2-(6-methoxy-2-naphthyl)propionic acid or a pharmaceutically acceptable salt or ester thereof, which comprises supplying R-2-(6-methoxy-2-naphthyl)-propionic acid...
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5041375 |
Method of producing carnitine
This invention relates to a method for producing carnitine comprising contacting, in a reaction medium, carnitinenitrile with (A) a nitrilase capable of hydrolyzing carnitinenitrile to form...
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5037751 |
Microbial purified esterases
A process for the preparation of a pharmaceutically active compound in a stereospecific form of the formula ##STR1## or a pharmaceutically acceptable salt or ester thereof, like an alkali metal...
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5037759 |
Process for the preparation of substituted phenoxy propanoic acids
The R-enantiomer of a compound of formula I: ##STR1## where Z is an optionally substituted cyclic organic moiety and C* represents an optically active carbon atom, may be prepared by supplying a...
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5034105 |
Carboxylic acid purification and crystallization process
A process for preparing a carboxylic acid of high purity comprises preparing an undersaturated solution of a salt of the carboxylic acid; subjecting the undersaturated salt solution to...
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5010012 |
Process for the enzymatic preparation of optically active phosphorus containing functional acetic acid derivatives
Resolution of the racemates of phosphorus-containing functional acetic acid derivatives can be carried out in high yield and in enantiomeric purity using hydrolases such as esterases and lipases.
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4997756 |
Process for preparing sorbic acid
A process for preparing sorbic acid which comprises treating sorbic aldehyde with at least one microorganism selected from Mycobacterium, Rhodopseudomonas, Streptomyces, Acetobacter, Alcaligenes...
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4996158 |
Optical resolution of racemic alcohols
A racemic alcohol is subjected to the optical resolution by irreversibly esterifying one of the two antipodes of the racemic alcohol with an acid anhydride or enol ester of a carboxylic acid in a...
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4985364 |
Preparation of cyclopropanecarboxylic acids
A process for the preparation of a (±)-trans-cyclopropanecarboxylic acid salt thereof of the formula ##STR1## in which R is halogen or C 1 -C 4 -alkyl, and R 1 is hydrogen or the equivalent...
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4971907 |
Method for producing pyruvic acid by fermentation
By cultivating microorganisms belonging to genus Torulopsis, requiring thiamine and biotin for their growth and having an ability to produce pyruvic acid, it is enabled to accumulate an appreciable...
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4968612 |
Continuous fermentation process for aromatic hydrocarbon bioconversion
This invention provides a continuous bioconversion process in which a non-growth toluene substrate is bio-oxidized by a specific microbe mutant strain to accumulated extracellular muconic acid at a...
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4957867 |
Production of cyclopentenones by enzyme resolution
A process for preparing an optically active cyclopentenone of the formula: ##STR1## wherein R is a hydrogen atom or a lower alkyl group and n is an integer of 4 to 8, which comprises contacting a...
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4925798 |
3-hydroxydicarboxylic acids and process for their production
3-hydroxydicarboxylic acids of 12-18 carbon atoms are produced microbiologically from n-alkanes employing the yeast mutant Candida tropicalis DSM 3152.
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4925797 |
Process for the decomposition of acrylamide
A process for the decomposition of acrylamide using an amidase (acrylamide amido hydrolase) enzyme in which the enzyme is induced in strains of Methylophilus methylotrophus. A method for inducing...
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4923811 |
Carrying out enzymatic oxidations
A process for carrying out enzymatic oxidations is described.
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4918013 |
Method for producing pyruvic acid by fermentation
The present invention relates to a method for producing pyruvic acid. This method consists of first producing Candida type cells at approximately 5 pH by using a culture medium comprising thiamine...
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4916066 |
Process for production of bishomo-gamma-linolenic acid
A process for the production of bishomo-γ-linolenic acid characterized by adding an additive to a culture medium, which additive is preferably selected from sesame oil, peanut oil, an extract from...
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4916067 |
Method for the preparation of sorbic acid by oxidizing 2,4-hexadienal with a microorganism
Sorbic acid can be prepared by the activity of a specific microorganism on 2,4-hexadienal. This method can be performed under mild conditions and, different from organo-chemical methods, is...
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4912042 |
Preparation of D-malic acid or derivative
D-malic acid is produced from D,L-malic acid by subjecting the racemate to the action of a microorganism or product thereof which assimilates L-malic acid but not D-malic acid, until the L-malic...
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4906568 |
Process for isolation of carnitinehydrolyase and an effector from enterobacteriaceae and use thereof to prepare carnitine
An enzyme carnitinehydrolyase is isolated from microorganisms belonging to the family Enterobacteriaceae, particularly Escherichia coli, Proteus vulgarius, Proteus mirabilis, Citrobacter freundii,...
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4898822 |
Process for preparing optically active indoline-2-carboxylic acid
A process for preparing optically active indoline-2-carboxylic acid by an optical resolution, which comprises subjecting a racemic ester of (R,S)-indoline-2-carboxylic acid having the general...
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4886750 |
Process for the preparation of a pharmaceutically active compound in a stereospecific form of the formula
A process for the preparation of a pharmaceutically active compound in a stereospecific form of the formula ##STR1## or a pharmaceutically acceptable salt or ester thereof, like an alkali metal...
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4882277 |
Continuous process for preparing organic acids by fermentation
Organic acids are prepared by fermentation and then separated from the fermentation broth by means of an electrodialysis. The present process does not require an addition of an alkali. The organic...
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4874700 |
Process for the production of L-malic acid
L-malic acid is separated by means of electrodialysis from reaction mixtures derived from biotechnical conversion of fumarate into L-malate. Fumaric acid present in the acid concentrate from the...
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4871667 |
Process for preparing muconic acid
Muconic acid is obtained from the culture of strains of Arthrobacter sp. mutant strains, strains belonging to Corynebacterium acetoacidophilum, Corynebacterium lilium, genus Brevibacterium or genus...
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4861724 |
Process for preparing optically active 2,2'-dihydroxy-1,1'-binaphthyl
The invention provides a process for preparing optically-active 2,2'-dihydroxy-1,1'-binaphthyl by subjecting esters of (+) 2,2'-dihydroxy-1,1'-binaphthyl to the enantioselective hydrolytic...
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4828993 |
Process for the preparation of organic acids
Organic acids are prepared from their salts electrodialytically. At the same time, another acid is converted electrodialytically into the corresponding salt. Both electrodialytic conversions take...
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4828992 |
Process for the manufacture of an antifungal antihypercholesterolemic .beta .
The process for the manufacture of the compound of the general structural formula ##STR1## which is a 3-hydroxy-3-methylglutarylcoenzyme A (HMG-CoA) synthase inhibitor and useful as an...
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4800162 |
Method for resolution of steroisomers in multiphase and extractive membrane reactors
This invention relates to the resolution of racemic mixtures of optically active compounds, including but not limited to the stereochemical purification of chiral organic esters, amides, carboxylic...
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4783404 |
L-aminoacid oxidase from yeasts of the genus cryptococcus, their preparation and use
Yeasts of the genus cryptococcus, preferably of the species C. Laurentii, form, in the presence of aminoacids, an L-aminoacid oxidase which stereospecifically converts L-aminoacids and their...
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4766071 |
Process for regenerating coenzymes
The invention relates to a process for the enzymatic preparation or regeneration of coenzymes selected from the group consisting of ATP, acetyl-CoA, acetyl-phosphate, NAD, NADP, NADH, and NADPH...
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4764464 |
Semisynthetic enzymes: apoproteins from heme proteins as hydrolases
Proteins having a hydrophobic cavity proximate to which is a residue promoting hydrolysis of functional moieties are effective semisynthetic hydrolases. Heme proteins from which the heme has been...
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4734367 |
Process to produce alpha-substituted derivatives of 3-hydroxypropionic acid
The manufacture of optically active compounds of the formula ##STR1## wherein R 1 signifies alkyl, phenyl or benzyl and R 2 signifies hydrogen or a customary ester residue, by the fermentative...
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4725542 |
Production of nylon 6,6 salt
This invention provides a process for producing nylon 6,6 salt which involves bioconversion of toluene to muconic acid in the presence of hexamethylenediamine to yield hexamethylenediamine muconate...
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4668628 |
Resolution of racemic mixtures of aliphatic acid esters
Racemic mixtures of partially water-soluble esters defined by the formula ##STR1## wherein R and R 1 represent hydrogen and C 1 -C 4 alkyl; R 2 represents C 1 -C 4 alkyl and X...
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4657863 |
Stabilization of a mutant microorganism population
This invention provides a process for stabilizing a population of a mutant microorganism in a bioconversion system whereby growth of revertant cells is suppressed. The process involves limiting a...
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4657862 |
Preparation of naturally-occurring C2-C5 alkyl esters of C4-C5 carboxylic acids by means of fermentation of C5-C6 amino acids in the presence of C2-C5 alcohols
Described is a process for the preparation of C 2 -C 5 alkyl esters of C 4 -C 5 carboxylic acids defined according to the structure: ##STR1## by means of fermentation of one or more C 5 -C 6 ...
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4649112 |
Utilization of xylan and corn fiber for direct fermentation by clostridium acetobutylicum
Butanol, acetone and fatty acids are produced by direct fermentation of a low-cost source of carbohydrates by Clostridium acetobutylicum. The carbohydrate source is selected from the group...
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4636467 |
Mixed microbial fermentation of carbonaceous matter to road de-icer
A process for production of mixed calcium-magnesium organic acid salts useful for de-icing obtained by anaerobic hydrolysis-fermentation of organic carbonaceous solids by a biologically active...
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4609623 |
Microbiologically produced D-2-hydroxy-4-methylpentanoic acid dehydrogenase, process for its production and its use
The enzyme D-2-hydroxy-4-methylpentanoic acid dehydrogenase has been prepared by culturing readily available Lactobacillus or Leuconostoc, microorganisms, such as Lactobacillus casei ssp....
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