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6268191 |
Enzyme immobilization by imbibing an enzyme solution into dehydrated hydrocolloid gel beads
Enzymes are immobilized for use in non-aqueous enzymatic reactions by dehydrating hydrocolloid gel beads having an average particle size of 5 to 150 microns and a network structure capable of...
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6261813 |
Two step enzymatic acylation
A method for derivatizing a compound having a hydroxyl group by back to back acylation is provided. The compound is acylated with a bifunctional acyl donor in the presence of a hydrolase to form an...
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6261812 |
Process for producing diglycerides
A process for producing diglycerides is provided by which high-purity diglycerides can be produced at a lower cost and more efficiently than conventional esterification and glycerolysis processes,...
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6248571 |
Method of producing dihydroxypyrimidine derivatives
A process for the preparation of dihydroxypyrimidine derivatives of the general formula: ##STR1## in which R 1 and R 2 are identical or different and are a hydrogen atom, aryl group, or a C 1 -C...
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6245365 |
Food products containing Mortierella sect. schmuckeri
The present invention relates to a process for producing arachidonic acid. In one embodiment, Mortierella sect. schmuckeri microorganisms are cultured in fermentation medium, preferably containing...
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6245535 |
Process for the preparation of HMG-COA reductase inhibitors
Disclosed is a process for producing a compound represented by general formula (II-a): ##STR1## (wherein R 1 represents a hydrogen atom, a substituted or unsubstituted alkyl group, or an alkali...
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6245537 |
Removing endotoxin with an oxdizing agent from polyhydroxyalkanoates produced by fermentation
Polyhydroxyalkanoate (PHA) that contains a pyrogen such as endotoxin due to a process of producing the PHA is treated to remove the pyrogen by a process that does not affect the inherent chemical...
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6238896 |
Process for producing malonic acid derivatives
The present invention relates to a method for preparing a malonic acid monoester represented by Formula (II): HOOCCH 2 COOR (II) wherein R is alkenyl, aryl, aralkyl or C 1 -20 alkyl,...
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6228623 |
Polyhydroxyalkanoates of narrow molecular weight distribution prepared in transgenic plants
Methods for the biosynthesis of polyhydroxyalkanoate homopolymers and copolymers are described. In a preferred embodiment, the polymers have a single mode molecular weight distribution, and more...
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6225438 |
Medium chain length PHA copolymer and process for producing same
This invention relates to polymer production and in particular to a novel copolymer and a process for microbiologically producing the same. More specifically this invention provides for a...
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6221658 |
Diacylglycerol kinase isoforms epsilon and zeta and methods of use thereof
Two novel diacylglycerol kinase (DGK) isoforms are disclosed. The cDNA of one DGK isoform, designated DGKε, is about 2.6 kb in length. The DGKε cDNA has an open reading frame encoding 567 amino...
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6221639 |
Process for preparing optically pure(S)-3,4-dihydroxybutyric acid derivatives
The present invention relates to a process for preparing optically pure (S)-3,4-dihydroxybutyric acid derivatives expressed by the following Formula 1 and more particularly, to a process that...
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6218156 |
Gene encoding carbonyl reductase, and methods for its use
An enzyme having carbonyl reduction activity of reducing a carbonyl compound asymmetrically to produce an optically active alcohol, a DNA coding the enzyme, a plasmid having the DNA, a transformant...
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6218157 |
Haloacetoacetate reductase, method for producing said enzyme, and method for producing alcohols using said enzyme
A novel enzyme is provided. This enzyme is capable of reducing 4-haloacetoacetic acid esters to produce (S)-4-halo-3-hydroxybutyric acid esters with high optical purity. The enzyme was isolated...
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6214611 |
Process for the preparation of prostaglandin precursors
A propargylic alcohol, enriched in the (R)-enantiomer, has the formula ##STR1## wherein R is C 1 -4 alkoxy, halogen, or C 1 -4 alkyl optionally substituted by OH or halogen. This is prepared by the...
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6187939 |
Method for preparing fatty acid esters and fuel comprising fatty acid esters
Fatty acid esters, which are prepared by reacting fats and oils with an alcohol in the absence of a catalyst under a condition under which at least one of the fats and oils and the alcohol is in a...
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6187741 |
Process for preparing saturated lactones, products produced therefrom and organoleptic uses of said products
A two phase environmentally friendly fermentation process for producing high yields of δ-decalactone and δ-dodecalactone from the corresponding unsaturated starting materials is carried out under...
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6174707 |
Process for producing L-allysine acetals
The present invention has for its object to provide a method for producing an L-allysine acetal which involves a fewer steps and is efficient. This invention relates to method for producing an...
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6168935 |
Preparation of optically active alcohol substituted with one or more halogen atoms
An optically active alcohol substituted with one or more halogen atoms, such as optically active 4-halo-3-hydroxybutyrate esters, is efficiently synthesized by using a secondary alcohol...
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6165757 |
Nitrogen feed in statin fermentation
A fermentation process is disclosed for producing an HMG-CoA reductase inhibitor such as lovastatin or compactin. In particular, it relates to a process wherein at least part of the assimilable...
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6146665 |
Entrapment or microencapsulation of drugs in a polyhydroxyalkanoate formed by enzyme synthesis
A hydrophilic or lipophilic drug is entrapped or microencapsulated in a polyhydroxyalkanoate homopolymer or copolymer. The homopolymer or copolymer is synthesized in an aqueous medium containing a...
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6146861 |
Processes for the production of amidase
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6117827 |
Biodegradable lubricant base oil and its manufacturing process
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6117658 |
Methods of making polyhydroxyalkanoates comprising 4-hydroxybutyrate monomer units
The PHA biosynthetic pathway is combined with a succinic semialdehyde metabolic pathway that metabolizes succinic semialdehyde via a 4-hydroxybutyryl-CoA intermediate in order to produce high...
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6103956 |
Polyhydroxyalkanoate synthesis in plants
Novel transgenic plants and plant cells are capable of biosynthesis of polyhydroxyalkanoate (PHA). Heterologous enzymes involved in PHA biosynthesis, particularly PHA polymerase, are targeted to...
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6096524 |
Chemically derived maltodextrins
High solids maltodextrin syrups, some of which are useful as the base for remoistenable adhesives, are prepared by a high solids alpha amylase enzyme conversion process. They are characterized by...
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6090598 |
Enzymatic process for interesterification of fats and oils using distillation
There is disclosed a process for modifying fats and oils by an interesterification reaction to efficiently increase concentrations of the desired triglycerides. In the process, a step for...
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6080562 |
HV/HB copolymer production
Microorganisms are modified to permit production of HV/HB copolymers from substrates such as glucose by inducing amiono acid overproduction in those capable of synthesising and polymerising...
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6080402 |
Immobilization of lipases by entrapment in silica matrices
Lipases are immobilized by entrapment in silicon-containing matrices obtained by hydrolysis of alkoxy-silicon compounds in the presence of a catalyst and additives such as proteins, polyhydroxy...
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6063602 |
Lipopolysaccharide biosurfactant
The invention relates to a new lipopolysaccaride biosurfactant, a strain of Acinetobacter calcoaceticus which produces this biosurfactant, and a process for its preparation. The biosurfactant has a...
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6046043 |
Method for the conversion of carbonyl compounds to their β-unsaturated derivatives using molecular oxygen as the oxidant
The present invention provides a general biocatalyst for transforming saturated carbonyl compounds to their α,β-unsaturated analogs. The transformation is regio- as well as stereoselective. These...
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6046040 |
Method for producing glycoconjugates
A method for producing glycoconjugate, which comprises the steps of: (i) binding a sugar residue to the side chain of a water-soluble polymer via a linker having a selectively cleavable linkage...
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6043063 |
Methods of PHA extraction and recovery using non-halogenated solvents
Polyhydroxyalkanoate (PHA) polyester is extracted from biomass by dissolving the PHA in a non-halogenated solvent which comprises a PHA-good solvent or a mixture thereof. Suitable PHA-good solvents...
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6043058 |
Preparation of cyclic depsipeptide compounds and a novel cyclic depsipeptide
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6033882 |
Chiral synthesis of 2-hydroxy carboxylic acids with a dehydrogenase
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6022717 |
Use of oxidation promoting chemicals in the oxidation oxidizable galactose type of alcohol configuration containing polymer
Process for the oxidation of the oxidizable galactose type of alcohol in oxidizable galactose type of alcohol configuration containing polymer, such as guar, with galactose oxidase in the presence...
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6005066 |
Aliphatic polyester composition
A polymer composition comprises an aliphatic polyester and at least one compound of the general formula (I): R 1 a (A)R 2 b , where A is a polyfunctional hydrocarbon group; R1 is an...
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5994105 |
Epimerase
A novel polypeptide, acylglucosamine 2-epimerase as shown in FIG. 1 and derivatives thereof, DNA coding for said enzyme, a recombinant vector containing said enzyme, a transformant integrated...
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5986095 |
Enantioselective preparation of halophenyl alcohols and acylates
A process is described for preparing a compound of the formula or the S-enantiomer thereof, wherein: R is alkyl, aryl, cycloalkyl, aralkyl, or cycloalkylalkyl, R 1 is halogen; R 2 is...
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5981240 |
Enzyme-catalyzed synthesis of macromolecules in organic solvents
A method is described for a simple, fast and efficient synthesis of homopolymers and copolymers by the enzymatic ring opening polymerization of lactones and lactides. The enzyme used is an ion...
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5968792 |
Calcium activation of lipase enzyme in process of pressure splitting glycerides
A process for pressure splitting glycerides into fatty acids and glycerols involving the steps of: (a) providing a glyceride feedstock; (b) providing a hydrolytic lipase enzyme; (c) providing an...
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5962724 |
High enantio-selective process for producing pure enantiomeric cyclopentane and cyclopentene-(β)-amino acids
The present invention relates to a highly enantioselective process for the preparation of enantiomerically pure cyclopentane- and -pentene β-amino acids of the general formula (I) ##STR1## in...
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5958743 |
Stereospecific bioconversion of benzyl acetoacetate to benzyl-(s)-(+)-hydroxybutyrate
A bioconversion process where benzyl acetoacetate is converted to benzyl-(S)-(+)-3-hydroxybutyrate.
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5952460 |
Process of recovering polymers of hydroxyalkanoic acids
A process of recovering PHA from a suspension which comprises particles of PHA in a liquid which comprises maintaining the suspension at a temperature at which the PHA melts and substantial...
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5945316 |
Lactic-acid-containing cyclic depsipeptides having 18 ring atoms as endoparasiticidal agents, and process for their preparation
The present invention relates to a process for the preparation of lactic-acid-containing, optically active, cyclic depsipeptides having 18 ring atoms with the aid of fungal strains of the species...
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5945318 |
Refining oil compositions
This invention relates to a process for treating an oil composition containing saturated and unsaturated fatty acids in the form of triglycerides, with at least some of the unsaturated fatty acids...
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5935828 |
Enzymatic production of monoglycerides containing omega-3 unsaturated fatty acids
An enzymatic process for preparing an oil based product significantly enriched in omega-3 fatty acids is disclosed. The process is a two-step procedure involving lipase-catalyzed...
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5925551 |
Aspergillus genus showing resistance to cerulenin and L-methionine analogue and a process for preparing mevinolinic acid therefrom
The present invention relates to a novel mutant of Aspergillus terreus which shows a resistance to both cerulenin and L-methionine analogue, and a process for preparing mevinolinic acid which...
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5917002 |
Poly(3-hydroxybutanoic acid) film
Poly(3-hydroxybutanoic acid) having a number average molecular weight of not less than 500,000 is oriented at a draw ratio of 2-fold or more to reproducibly obtain a film made of...
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5908769 |
Solvent-free method for reacting short-chain alcohols and acids using C. antarctica lipase immobilized to acrylic resin
An ester compound is prepared with a greatly improved efficiency by reacting a liquid alcohol with a liquid organic acid at a temperature of about 30 to 70° C. in the presence of a lipase without...
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