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7588923 |
Method to increase the yield and improve purification of products from transaminase reactions
A process for producing high yields of enantioselective amino acids and chiral amines by reacting a keto acid or ketone and an amino acid donor in the presence of a transaminase biocatalyst to...
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7575906 |
Catalase decomposition of hydrogen peroxide in surfactants
A process comprising the steps of continuously adding a catalase enzyme to a process stream, wherein the process stream comprises an amine oxide surfactant and hydrogen peroxide; and mixing the...
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7572608 |
R-hydroxynitrillyases having improved substrate tolerance and the use thereof
The invention relates to R-hydroxynitrillyases from the family of Rosaceae that are characterized by an improved substrate tolerance and increased stability. In the active center of the...
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7531344 |
Induction and stabilization of enzymatic activity in microorganisms
The present invention is directed to methods for inducing desired activity in enzymes or microorganisms capable of producing the enzymes. The invention is further directed to methods of stabilizing...
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7531330 |
Modified S-hydroxynitrile lyase
This invention relates to S-hydroxynitrile lyase having excellent tolerance to heat, organic solvents, and the like, which is obtained by modifying at least one amino acid in the helix D3, helix A,...
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7514243 |
Process for producing dipeptides
The present invention provides a process for producing a dipeptide which comprises culturing in a medium a microorganism which has the ability to produce a protein having the activity to form the...
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7491520 |
Biochemical synthesis of 6-amino caproic acid
The invention relates to biochemical synthesis of 6-amino caproic acid from 6-aminohex-2-enoic acid compound or from 6-amino-2-hydroxyhexanoic acid, by treatment with an enzyme having α,β-enoate...
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7470526 |
Chemo-enzymatic process for the preparation of escitalopram
A process for preparing an intermediate for synthesizing escitalopram and the pharmaceutically acceptable salts thereof from...
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7465826 |
Chiral 3-carbamoylmethyl-5-methyl hexanoic acids, key intermediates for the synthesis of (S)-pregabalin
The invention encompasses the synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid, (S)-Pregabalin, via the intermediate, (3R)-5-methyl-3-(2-oxo-2{[(1R)-1-phenylethyl]amino}ethyl)hex
anoic acid.
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7446187 |
Plasmids and utilization thereof
A shuttle vector is constructed by preparing a DNA region replicable in bacteria belonging to the genus Rhodococcus from a Rhodococcus -derived plasmid having the nucleotide sequence set forth...
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7445793 |
Support for tissue regeneration and process for producing the same
The present invention provides a scaffold in which cells can be stably retained and grafted in a uniform distribution state in the culture, preferable proliferation ability and viability can be...
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7432102 |
Transformants producing substance pf1022 derivatives, methods for producing the same, and novel biosynthesis genes
An objective of the present invention is to provide a method for producing substance PF1022 derivatives, in particular PF1022-220 and PF1022-260, by a direct fermentation method, and a transformant...
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7407779 |
Modification of solid 3-sn-phosphoglycerides
Methods for hydrolyzing solid ungranulated lysophosphatidylcholine with phospholipase A 2 are provided. Also disclosed are methods for making a lipid matrix of lysophosphatidylcholine,...
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7399616 |
Enzymatic synthesis of Nα-acyl-L-arginine esters
The invention relates to a process for preparing a Na-acyl-L-arginine ester, derived from fatty acids and esterified dibasic amino acids, according to the following formula (I), where: X— is...
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7374926 |
Enantioconvergent chemoenzymatic synthesis of (R)-γ-amino-β-hydroxybutyric acid ((R)-GABOB)
The present invention particularly relates to a chemoenzymatic process for the stereoselective preparation of both enantiomers of 3-hydroxy-4-trityloxy butanenitrile key intermediates for the...
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7364882 |
Enzymatic reduction of a nitrile containing compound to the corresponding amine
A new class of enzymes that catalyze the conversion of a nitrile containing compound to the corresponding amine (such as a primary amine) are disclosed. Such enzymes are referred to herein as...
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7364881 |
Biological process for the conversion of nitroarenes to ortho-aminophenols using recombinant E. coli strains
A process for biological production of ortho-aminophenols from nitroaromatic compounds using recombinant E. Coli strains. The process uses an enzyme system that makes use of a nitroreductase...
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7364787 |
Sphingolipid ceramide N-deacylase, methods for producing sphingolipids and sphingolipid derivatives, and sphingolipid ceramide N-deacylase gene
The present invention relates to a novel sphingolipid ceramide N-deacylase (SCDase) having a wide substrate specificity; a method for enzymatically producing a lysosphingolipid or a sphingolipid...
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7351786 |
Polyhydroxyalkanoate containing unit having cyclohexyl structure at side chain, production process therefor, and binder resin containing polyhydroxyalkanoate
Disclosed are a polyhydroxyalkanoate, containing in a polymer molecule thereof a monomer unit represented by the following general formula (1):
(wherein R1 represents a substituent to a...
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7338792 |
Process for the preparation of D-pantothenic acid and/or salts thereof
The invention provides a process for the preparation of D-pantothenic acid and/or salts thereof or feedstuffs additives comprising these by fermentation of microorganisms of the Bacillus group,...
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7332297 |
Enzymatic polymerization
The invention relates to a novel method for enzymatic polymerization which includes (1) obtaining a reaction mixture including a monomer, a template, and an enzyme; and (2) incubating the reaction...
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7309590 |
Method for producing an aqueous acrylamide solution with a biocatalyst
The invention relates to a method and device for producing an aqueous acrylamide solution by hydrating acrylonitrile in an aqueous solution while in the presence of a biocatalyst.
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7309582 |
Polymer-template complex produced by enzymatic polymerization
The invention relates to a novel method for enzymatic polymerization which includes (1) obtaining a reaction mixture including a monomer, a template, and an enzyme; and (2) incubating the reaction...
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7291490 |
Nucleic acid fragment encoding an NRPS for the biosynthesis of anthramycin
Genes and proteins involved in the biosynthesis of benzodiazepines by microorganisms, including the genes and proteins forming the biosynthetic loci for the benzodiazepine anthramycin from ...
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7267969 |
Thermostable omega-transaminases
Thermostable omega-transaminases, particularly thermostable omega-transaminases which have a high reaction rate and which are tolerant to high concentrations of donor amine, can be used to enrich...
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7232583 |
Method for preparing isothiocyanate(s) from cruciferous plant material
A method for preparing an isothiocyanate product from a cruciferous plant material is disclosed which is capable of stably preparing an isothiocyanate product in a sufficient amount in a high yield...
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7229803 |
Reaction of (di)amines in the presence of a lysine oxidase and of a reducing agent
The invention relates to methods for reacting (di)amines as substrates in the presence of a lysine oxidase arid a reducing agent, resulting in alcohols, diols or cyclic secondary amines. In a...
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7220561 |
Processes for enhanced production of pantothenate
The present invention features improved methods for producing pantoate and pantothenate utilizing microorganisms having modified pantothenate biosynthetic enzyme activities. In particular, the...
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7208302 |
Deracemisation of amines
The present invention relates to a method for the deracemisation or chiral inversion of chiral amines by enzymatic treatment. The method employs a stereoselective enzymatic conversion and either a...
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7198926 |
Preparation of (E)- and (Z)-2-methyl-2-butenoic acids
A method has been developed to prepare (E)- and (Z)-2-methyl-2-butenoic acids (2M2BA) from a mixture of (E,Z)-2-methyl-2-butenenitriles (2M2BN) by the regioselective hydrolysis of (E)-2M2BN to...
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7183089 |
Method for enhancing production of isoprenoid compounds
The present invention provides methods of producing an isoprenoid or an isoprenoid precursor in a genetically modified host cell. The methods generally involve modulating the level of...
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7166452 |
Aminoketone asymmetric reductase and nucleic acid thereof
A protein, which is an aminoketone asymmetric reductase, having an effect of producing d-pseudoephedrine by acting on 1-2-methylaminopropiophenone, and having the following physiochemical...
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7135314 |
Human phosphatidic acid phosphatase
This invention relates to a biotechnology invention concerning human phosphatidic acid phosphatase. More particularly, this invention relates to three variants of human phosphatidic acid...
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7132267 |
Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives and vicinal cyano, hydroxy substituted carboxylic acid esters
The present invention provides methods and compositions for preparing 4-substituted 3-hydroxybutyric acid derivatives by halohydrin dehalogenase-catalyzed conversion of 4-halo-3-hydroxybutyric acid...
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7125693 |
Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives
The present invention provides methods and compositions for preparing 4-substituted 3-hydroxybutyric acid derivatives by halohydrin dehalogenase-catalyzed conversion of 4-halo-3-hydroxybutyric acid...
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7091011 |
3-hydroxycarboxylic acid production and use in branched polymers
This invention relates to a process for the preparation of a 3-hydroxycarboxylic acid from a 3-hydroxynitrile. More specifically, 3-hydroxyvaleronitrile is converted to 3-hydroxyvaleric acid in...
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7078225 |
Method for enzymatically producing an optically active cyanohydrin
The present invention relates to an enzyme reaction method which comprises performing an enzyme reaction, using an immobilized enzyme having a water content of 10% by weight or more as an enzyme...
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7070941 |
Methods and compositions for tagging via azido substrates
The invention provides methods and compositions for azide tagging of biomolecules. In one embodiment of the invention, proteins are tagged by metabolic incorporation of prenylated azido-analog...
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7067291 |
Biocatalytic preparation of enantiomerically enriched aminopentanenitrile
Methods for preparing enantiomerically enriched aminopentanenitriles are provided. The methods involve selective acylation of an enantiomeric mixture of 3-aminopentanenitrile or selective...
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7056540 |
Enzymatic process for the preparation of optically active alcohols from ketones using tuberous root Daucus carota
The present invention relates to an enzymatic process for the preparation of optically active chiral alcohols using tuberous root Daucus carota ; particularly invention relates to an enzymatic...
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7049107 |
Method of producing phosphatidylserine
A novel method of producing PS is described herein. The method first involves producing PLD enzyme through the use of enzyme-producing microorganisms. The PLD enzyme is reacted with a lecithin and...
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7045321 |
POLYHYDROXYALKANOATE CONTAINING UNIT WITH PHENYLSULFANYL STRUCTURE IN THE SIDE CHAIN, PROCESS FOR ITS PRODUCTION, CHARGE CONTROL AGENT, TONER BINDER AND TONER WHICH CONTAIN NOVEL POLYHYDROXYALKANOATE, AND IMAGE-FORMING METHOD AND IMAGE-FORMING APPARATUS WHICH MAKE USE OF THE TONER
A polyhydroxyalkanoate characterized by having in the molecule a unit represented by Chemical Formula (1):
wherein n may assume any one integral value within the range of from 1 to 8. Also...
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7034131 |
Nucleic acid derivatives
A compound which comprises a backbone having a plurality of chiral carbon atoms, the backbone bearing a plurality of ligands each being individually bound to a chiral carbon atom of the plurality...
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7018818 |
Intermediates in the preparation of therapeutic fused bicyclic amino acids
The invention presents compounds of formula (I),
where R represents H or a suitable carboxylic acid protecting group, which are intermediates in the preparation of therapeutic fused bicyclic...
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7005281 |
Enzymatic process for preparing organosilicon group containing photoinitiators
The invention relates to a process for preparing organosilicon group containing photoinitiators of the formula (I), wherein m is a number from 1 to 200; q is 0 or 1; A is IN-C(O)—O—CHR 3...
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6991926 |
Method comprising the indirect electrochemical regeneration of NAD(P)H
A method comprising the indirect electrochemical regeneration of NAD(P)H in enzymatic substrate conversions which are catalyzed by monooxygenases, for example, is described. In particular, a method...
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6960465 |
Increased cell resistance to toxic organic substances
Recombinant microorganisms and related methods of use to enhance tolerance to toxic substances. In particular, such microorganisms and methods can be used to increase solvent production.
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6951746 |
Method of manufacturing polyamine composition
After yeast somatic components are digested with nuclease or hydrolyzed with alkali, polyamine is recovered to obtain a polyamine composition in volume efficiently at a high recovery rate from...
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6943006 |
Method for metabolizing carbazole in petroleum
A method for selective cleavage of C—N bonds genes that encode for at least one enzyme suitable for conversion of carbazole to 2-aminobiphenyl-2,3-diol are combined with a gene encoding an...
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6936444 |
Process for the preparation of L-phosphinothricine by enzymatic transamination with aspartate
The patent application describes a process for the enzymatic chiral synthesis of L-phosphinothricin by transamination from its corresponding keto acid PPO with aspartate as amino donor. It is...
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