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RE35230 Enantiomeric enrichment of cyanohydrins  
A method of enantiomerically enriching chiral cyanohydrins is disclosed that involves selective cleavage of the unwanted enantiomer into its cleavage products HCN and the corresponding aldehyde or...
5508180 Biocatalytic oxidation using soybean peroxidase  
Biocatalytic oxidative processes wherein oxidizable substrates are reacted in the presence of soybean peroxidase are described. Preferred biocatalytic oxidative reactions include the oxidation of...
5498625 Substantially pure enantieners of 2-azabicyclo(2.2.1)hept-5-en-3-one  
Lactams of 1-amino-3-carboxylic acid cyclic compounds are produced in enantiomeric form, together with an enantiomer of the corresponding ring-opened amino-acid or ester, by reaction of the racemic...
5444087 Manumycin compounds  
Manumycin C, Manumycin D and Manumycin E, obtainable by cultivation of a strain of Streptomyces sp. A.T.C.C. No. 55484, oxidized derivatives thereof and salts and prodrugs of these compounds. The...
5437991 Process for the synthesis natural aromatics  
A novel method for the production of natural aromatic ester compounds such as methyl anthranilate, ethyl anthranilate butyl anthranilate methyl cinnamate and methyl salicylate comprises the...
5431896 Microbial immunoregulant  
Described is a new immunosuppressant, L-687,819, a C-31 demethylated derivative of L-683,795 (FK-523), produced under fermentation conditions utilizing the new mutant microorganism, Streptomyces...
5422256 Production of anthranilic acid by a strain of Bacillus subtillis resistant to sulfaguanidine and fluorotryptophan  
A strain of Bacillus subtilis which is a tryptophan auxotroph, resistant to sulfaguanidine and flourotryptophan and produces anthranilic acid in a nutrient solution containing L-tryptophan, and...
5418161 Microbial degradation of indigo and indigo carmine with bacteria strain  
Biologically pure strains of microorganisms capable of degrading indigo and indigo carmine are disclosed. A preferred strain is bacteria strain ATCC 55396. The bacteria is used for treating water...
5395758 Process for production of amide compounds using agrobacterium radiobacter  
There is disclosed a process for production of amide compounds which includes converting a nitrile compound into an amide compound using a cultured broth of bacterial cells, or bacterial cells or...
5380654 Process for the preparation of epoxides of means of microorganisms  
2,3-Epoxypropyl ethers valuable as intermediates for preparing medicaments and the like are prepared from the corresponding allyl ethers by means of epoxide-producing microorganisms belonging to...
5360724 Process for the preparation of chiral 1-aryl-2-aminopropanes  
One chiral form of a 1-aryl-2-aminopropane is produced in preference to its enantiomer by allowing a 1-arylpropan-2-one to react with a 1-amino-1-phenylethane of predominantly one chiral form and...
5350871 Method of preparing optically active cyanohydrins  
The invention relates to a method of preparing an optically active cyanohydrin by addition of hydrogen cyanide to a carbonyl compound, selected from aldehydes and ketones, in the presence of...
5346816 Enzymatic process for the enantioselective preparation of optically active cyanohydrins  
Enantioselective process for the preparation of the S enantiomer of an optically active cyanohydrin by reacting an aldehyde or an asymmetric ketone with a cyanide group donor in the presence of an...
5316917 Automated analysis of free l-carnitine and total short-chain acylcarnitine  
Disclosed is a method of assaying free L-carnitine and total short-chain acylcarnitine in blood. The method uses essentially protein-free samples of plasma or serum and comprises (a) obtaining a...
5300430 Biocatalytic process for the production of L-(-)-carnitine from crotonobetaine and strains of proteus for use in said process  
A process is described for stereospecifically hydrating crotonobetaine to L-(-)-carnitine via the action of an enzyme produced by four new strains of Proteus mirabilis (NRRL B-18480, NRRL B-18481,...
5298409 Antibody-enhanced stereospecific hydrolyses  
Hydrolyses of various chiral compounds are performed in stereospecific manner by antibodies generated from analogs of transition states of the compounds. The compounds susceptible to such...
5290698 Streptoverticillium ferm P-10489 which produces antitumor agent BE-13793C  
A novel antitumor substance BE-13793C or a pharmaceutically acceptable salt thereof, which is represented by the following formula: ##STR1## an anticancer agent comprising the novel substance or a...
5290772 Immunosuppressant agent  
Described is a process for producing an immunosuppressant, "demethimmunomycin" (L-683,7411) a C-31 demethylated analog of L-683,590 under fermentation conditions utilizing the microorganism,...
5288624 Cercosporal fungicide compositions and methods of use  
The present invention relates to a funcidally active principle (fungicidal agent) obtainable by cultivation of fungi of the genus Phaeoramularia or Cercospora. The principle can be used for...
5278054 Process for the enzymatic hydrolysis of a carboxylic acid derivative  
A process for the enzymatic hydrolysis of a carboxylic acid derivative by dissolving the carboxylic acid derivative in an organic solvent which is miscible with water only to a slight extent,...
5275941 Process for the preparation of N-protected dialkyl (2S,3S)-3-ethylaspartates  
The invention relates to a process for the preparation of N-protected dialkyl (2S,3S)-3-ethylaspartates or their salts from unpurified (2S,3S)-3-ethylaspartic acid obtainable by enzymatic amination...
5275950 Process for the preparation of a renin inhibiting compound  
Intermediates and a process for their preparation are disclosed which are useful for the preparation of a renin inhibiting compound of the formula: ##STR1## wherein R is a nitrogen-containing...
5266463 Highly sensitive assay method for L-carnitine and composition for practicing same  
A method of assaying L-carnitine in a specimen comprises reacting a specimen containing L-carnitine with: a) L-carnitine dehydrogenase having coenzymes of the thio-NAD group and of the NAD...
5258292 Enzymic process for the synthesis of ammonium adipate  
The invention relates to an enzymic process for the synthesis of ammonium adipate by the hydrolysis of adipamide and/or ammonium adipamate by means of a particular polypeptide or a recombinant...
5248601 Process for preparing L(-)-carnitine chloride  
A biotechnological process for preparing L(-)-carnitine chloride, having the formula ##STR1## comprising: (a) reacting a racemic ester of (R,S)-3,4-epoxybutyric acid having the formula ##STR2##...
5238838 L-carnitine amidase produced by a microorganism  
The microorganism DSM 6230 produces an enzyme, L-carnitine amidase. This microorganism and/or the enzyme which it produces can selectively hydrolyze L-carnitine amide and/or the L-component of...
5223416 Process for producing R(-)-mandelic acid and derivatives thereof  
A process for the predominantly producing R(-)-mandelic acid or a derivative thereof which comprises subjecting (i) R,S-mandelonitrile or a derivative thereof, or (ii) a mixture of prussic acid and...
5217886 Method for the production of (-)-4-difluoromethyl-ornithine  
The present invention is directed to a process for producing (-) 2-substituted-ornithines comprising contacting a 2-substituted-piperidone with L-α-E-aminocaprolactam-hydrolas in the presence of a...
5210031 Process for the production of R(-)-4-halo-3-hydroxybutyronitrile  
A process for the production of a 4-halo-3-hydroxybutyronitrile which comprises reacting an epihalohydrin with a halohydrin-halide-lyase originating from a microorganism selected from the group...
5200330 Method for the preparation of methyl anthranilate  
A process for the preparation of "natural" methyl anthranilate which comprises the microbial N-demethylation of methyl N-methyl-anthranilate is disclosed.
5196327 Process for producing antifungal fermentation products and compositions thereof  
A mixture of derivatives of 2-amino-3,4,5,14-tetrahydroxy-6-eicosenoic acid has been isolated from a culture medium after cultivation of microorganisms belonging to the genus Aspergillus. The...
5188951 Enzymatic synthesis of soluble phosphatides from phospholipids  
A method of preparing a soluble monovalent salt of a phosphatidyl ester which comprises reacting a phospholipid with a primary alcohol in the presence of an enzyme catalyst in a divalent cationic...
5187093 Microorganisms useful in the process for the production of l-carnitine  
Process for the production of L-carnitine utilizing a microorganism. The microorganism is cultivated with crotonobetaine and/or γ-butyrobetaine in the presence of a growth substrate. The enriched...
5179014 Process for the preparation of amides using microorganisms  
A process for the production of amides utilizing microorganisms is described, which comprises subjecting nitriles having from 2 to 6 carbon atoms to the action of a microorganism belonging to the...
5177242 Process for preparing optically active cyanohydrins with enzymes  
The reaction time and ease of handling of reactants in the known process of forming optically active (S)-cyanohydrins by reacting aldehydes with hydrocyanic acid in the presence of the enzyme...
5169777 Composition of biologically pure cultures of Alcaligenes denitrificans denitrificans and a porous carrier useful for biodegradation  
The present invention is a process of degrading 1,4-dibenz-oxazepine with a icroorganism enzymatically capable of converting the 1,4-dibenz-oxazepine into at least o-nitrophenol which is further...
5166061 Process for the production of 4-halo-3-hydroxybutyronitrile with Corynebacterium or Microbacterium  
A process for the production of a 4-halo-3-hydroxybutyronitrile which comprises reacting a 1,3-dihalo-2-propanol with a dehalogenating enzyme originating from a Corynebacterium or a Microbacterium...
5162219 Preparation of amine-enriched proteins having an increased isoelectric point  
Amine-enriched proteins, having an increased isoelectric point are provided by reacting a naturally occurring protein with an amide bond forming agent in the presence of a polyamine or a salt...
5162212 Transaminase from E. coli DH-1 (ATCC 33849)  
A new transaminase has been isolated from E. coli DH-1 (ATCC 33849). It is possible to use the transaminase with great efficiency to prepare L-phosphinothricin and gamma-aminobutyric acid from...
5153125 Process for producing lysophospholipids-containing phospholipids with reduced neutral lipid content  
Lysophospholipids-containing phospholipids with reduced neutral lipids content can be produced by a process which comprises subjecting neutral lipids- and lysophospholipids-containing phospholipids...
5153127 AB-011 Antibiotics and process for producing them  
The AB-011 Antibiotics and the main components thereof: AB-011a and AB-011b, obtained by the controlled aerobial cultivation of Streptomyces s.p. NCIB 12629 in an aqueous nutrient cultivation...
5143828 Method for synthesizing an enzyme-catalyzed polymerized monolayer  
A method for synthesizing enzyme-catalyzed polymers using the Langmuir-Blodgett technique. In one embodiment, the process comprises spreading one or more enzyme-polymerizable monomers on a...
5135860 Process for preparing glyoxylic acid/aminomethylphosphonic acid mixtures  
The invention provides a process for producing mixtures of glyoxylic acid and aminomethylphosphonic acid. The process comprises reacting glycolic acid and oxygen in an aqueous solution in the...
5135858 Process for biological production of organic acids  
An improved biological conversion of a nitrile such as acrylonitrile or a cyanopyridine into the corresponding carboxylic acid such as acrylic acid or a nicotinic acid by the action upon the...
5122461 Preparation of pyrocatecholic compounds  
The invention relates to a novel method for preparing pyrocatecholic compounds from monophenolic compounds using catalysis by monophenol monooxygenase in an aqueous solution containing metal ions....
5122462 Process for the enzymatic preparation of optically-active cyanohydrins  
The preparation of optically-active cyanohydrins from the corresponding oxo compounds is disclosed. The reaction of the oxo compounds with hydrocyanic acid is carried out in an organic solvent in...
5116744 Microbial cyanide converting enzymes, their production and use  
A novel cyanide converting enzyme, a "cyanidase" is described. The enzyme is extremely efficient in reducing substantial concentrations of cyanide to very low levels in a broad pH, and temperature...
5098836 Deoxygenation in field preparation of polymers in aqueous solution  
In a process for polymerizing monomers with free-radical initiators in aqueous solution to produce polymers useful in oil field applications, wherein said polymerization process employs an...
5087614 Enzyme inhibitor and method of producing the same  
Novel peptide analogues which exhibit inhibitory activity against aspartic proteinases, a novel species of actinomycetous microorganism which produces said novel peptide analogues, a process for...
5079167 Method of racemate resolution  
The invention relates to a method for resolving carbamate racemates of amino acids or norephedrine by enzmatic resolution.