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5877272 Bacteriocin from lactococcus lactis  
A bacteriocin produced by Lactococcus lactis NRRL-B-18535 is described. The bacteriocin is useful in foods and other materials and has a wide spectrum of activity against Gram-positive bacteria in...
5874262 Microbiological process for the preparation of (S,S)-N,N'-ethylenediaminedisuccinic acid  
A microbiological process for the preparation of N,N'-ethylenediaminedisuccinic acid of formula (1), by (a) precultivation of a strain of the genus Amycolatopsis orientalis on a specified nutrient...
5869042 Methods for controlling above-ground plant diseases using antibiotic-producing bacillus sp. ATCC 55608 or 55609  
Above-ground fungal and bacterial infections of plants are treated by applying to the plants an antibiotic-producing Bacillus sp. strain ATCC 55608, 55609, 53522 and/or zwittermicin-A antibiotic...
5846752 Mutant urease and method of use for determination of urea  
A mutant urease of Klebsiella aerogenes characterized as αH219Q having a glutamine (Q) in position 219 in place of histidine (H). The resulting enzyme has a low affinity for substrate (high value...
5846792 Method of producing (R)-2-amino-1-phenylethanol and opticaly active phenylserine and their halogen substituted products using tyrosine decarboxylase  
Tyrosine decarboxylase, or microorganisms of the genuses Enterococcus, Lactobacillus, Providencia, Fusarium, and Gibberella were reacted with a mixture of the enantiomers of threo-3-phenylserine or...
5837505 Melanin production from transformed escherichia coli  
The present invention is directed to a process for producing melanins, their precursors and their analoges, hereinafter referred to generically as melanins. According to the invention, melanins are...
5834261 Method for the production of chiral vicinal aminoalcohols  
The disclosure describes a method for the preparation of chiral vicinal aminoalcohols in high optical purity. The method combines the stereoselective reduction of the keto group of a β-ketoacid,...
5827699 Strain of Rhodococcus rhodochrous as a producer of nitrile hydratase  
This invention provides a new strain Rhodococcus rhodochrous having a high nitrile hydratase activity and capable of hydrating aliphatic and aromatic nitriles to corresponding amides. An isolated...
5821112 Biological odor metabolizing compositions and methods of use  
Mixed bacterial compositions minimally contain a mixed population of bacteria including at least one species of Nitrosomonas capable of converting ammonia to nitrite, at least one species of...
5817362 Method for inhibiting bacteria using a novel lactococcal bateriocin  
A novel bacteriocin produced by Lactococcus lactis NRRL-B-18535 is described. The bacteriocin is useful in foods and other materials and has a wide spectrum of activity against Gram-positive...
5817357 Food composition incorporating a novel lactococcal bacteriocin  
A bacteriocin produced by Lactococcus lactis NRRL-B-18535 is described. The bacteriocin is useful in foods and other materials and has a wide spectrum of activity against Gram-positive bacteria in...
5801023 Antiparasitic pyrrolobenzoxazine compounds  
This invention provides compounds of the following chemical formula or their pharmaceutically-acceptable salts: ##STR1## wherein R is hydrogen or chloro. Also, the present invention provides a...
5798234 Method for the directed modification of enzymes, modified enzymes and their use  
Enzymes with modified substrate specificity and methods of obtaining same by the steps of a) determining the structure of two or more enzymes in the same group, b) comparing the structure of the...
5795750 Process for the continuous enzymatic extraction of hydrophobic products and device suitable therefor  
In a process for the continuous enzyme-catalyticzed enzymatic production of hydrophobic products in an aqueous solution of a reaction mixture, the product is extracted from the product containing...
5777190 Method of controlled reduction of nitroaromatics by enzymatic reaction with oxygen sensitive nitroreductase enzymes  
A method for the controlled reduction of nitroaromatic compounds such as nitrobenzene and 2,4,6-trinitrotoluene by enzymatic reaction with oxygen sensitive nitroreductase enzymes, such as...
5773291 Non-melanotytic mammalian cell constitutively expressing biologically active human tyrosinase and use thereof  
This invention provides a non-melanocytic eucaryotic cell constitutively expressing biologically active human tyrosinase. The present invention also provides methods of producing biologically...
5766893 Biotechnological process for the preparation of cyclic s-alpha-imino carboxylic acids and r-alpha-imino carboxamides  
Microorganisms of interest are capable of utilizing α-imino carboxamides, in the form of the racemate or of its optically active isomers, of the general formula ##STR1## wherein A together with...
5763235 5-aminolevulinic acid producing microorganism and process for producing 5-aminolevulinic acid  
A microorganism that produces 5-aminolevulinic acid, wherein the microorganism has a 5-aminolevulinic acid dehydratase variant having a reduced inhibitor constant for a 5-aminolevulinic acid...
5763249 Antibody-mediated reduction of α-ketoamides  
Monoclonal antibodies raised against a 4-nitrophenyl phosphonate hapten catalyze the stereospecific reduction of an α-ketoamide to the corresponding α-hydroxyamide in the presence of an...
5759824 Genes for butyrobetaine/crotonobetaine-l-carnitine metabolism and their use for the microbiological production of l-carnitine  
An isolated DNA fragment including the genes bcoC, bcoA/B, bcoD coding for the enzymes for L-carnitine biosynthesis in γ-butyrobetaine/crotonobetaine metabolism and, additionally, including the...
5756321 Process for enzymatic acylation of alcohols with alkoxyvinyl acetates by transesterification  
Methods for the enzyme catalyzed acylation of primary and secondary alcohols using an enol ester as the acyl donor are described. The acylation occurs in organic media, and is enantioselective for...
5753471 Biotechnological perparation of alcohols, aldehydes and carboxylic acids  
A process for the biotechnological preparation of alcohols, aldehydes and carboxylic acids by oxidation of compounds of the formula R 1 --C(CH 3 )CR 2 R 3 , where R 1 , R 2 and R 3 have the...
5750381 Enzymatic process for making morphine-6-glucuronide or substituted morphine-6-glucuronide  
A method of making morphine-6-glucuronide comprising the selective enzymatic cleavage of the 3-glucuronide moiety in morphine-3, 6-glucuronide or substituted morphine-6-glucuronide using at least...
5736382 Bacillus cereus strain DGA34  
A novel strain of Bacillus cereus, designated DGA34, has been isolated from the environment. The strain DGA34 is one of a number of B. cereus strains which are useful as biocontrol agents to combat...
5733755 Method for the enantioselective synthesis of chiral derivatives of S-3-(4'- t  
A method for manufacturing S-3-(4'-tert-butyl)-phenyl-2-methyl propylamines having the structure I ##STR1## where NR 1 R 2 is a dialkylamine group, pyrrolidine, piperidine, or cis-3,5-dimethyl...
5731175 Method of producing (R)-2-amino-1-phenylethanol and optically active phenylserine and their halogen substituted products using microbes  
Tyrosine decarboxylase, or microorganisms of the genuses Enterococcus, Lactobacillus, Providencia, Fusarium, and Gibberella were reacted with a mixture of the enantiomers of threo-3-phenylserine or...
5716814 Methods for making lysophosphatidylcholine  
Methods for making lysophosphatidylcholine are provided, comprising hydrolysis of a mixture of phosphatidylcholine and an agent with phospholipase A 2 . Also disclosed are methods for making a...
5714356 Enzymic process for preparing aliphatic S-cyanohydrins  
Process for preparing (S)-cyanohydrins by reacting aldehydes or asymmetrical, aliphatic ketones with hydrocyanic acid in the presence of the (S)-oxynitrilase from Hevea brasiliensis at temperatures...
5702923 Method of making a lactococcal bacteriocin  
A method of making a bacteriocin produced by Lactococcus lactis NRRL-B-18535 is described. The bacteriocin is useful in foods and other materials and has a wide spectrum of activity against...
5700670 Method for producing optically active ester of γ-substituted-β-hydroxybutyric acid  
Microbial cells and/or a preparation therefrom of a microorganism is allowed to act on an ester of γ-substituted-acetoacetic acid, and a carbonyl group at its β-position is stereospecifically...
5695969 Process for producing N-substituted polyhydroxy nitrogen-containing heterocycles  
A process for producing N-substituted amino compounds, a process for oxidizing an N-substituted amino compound with a microbe, or cell fragment or cell free extract thereof, and a process for...
5695984 Process for the preparation of antibiotics 10381B  
Antibiotic 10381a 1 , wherein R is hydrogen, is a cytosine-containing antibiotic producible by culturing the novel microorganism Streptomyces arginensis in an aqueous medium and isolation thereof....
5688933 Preparation of biologically active compounds from substantially pure enantiomers of 2-azabicyclo 2.2.1!hept-5-en-one  
Lactams of 1-amino-3-carboxylic acid cyclic compounds are provided in enantiomeric form, together with an enantiomer of the corresponding ring-opened amino-acid or ester, by reaction of the racemic...
5667531 Dye compositions containing purified polyporus laccases and nucleic acids encoding same  
The present invention relates to isolated nucleic acid constructs containing a sequence encoding a polyporus laccase, and the laccase proteins encoded thereby.
5661014 Chiral compounds and their resolution synthesis using enantioselective esterases  
Enantiomeric glutarimides such as aminoglutethimide and rogletimide are prepared by cyclisation of a corresponding ester-nitrile which is a good substrate for biotransformation with an...
5627056 Method of synthesizing lipids and cosmetic composition comprising them  
An efficient method of producing phytosphingosine-containing ceramide one comprising: (a) obtaining a phytosphingosine base from tetraacetylphytosphingosine (TAPS) by a deacetylation reaction...
5622846 Biotechnological process for the preparation of cyclic-s-α-imino carboxylic acids and r-α-imino carboxamides  
Microorganisms of interest are capable of utilizing α-imino carboxamides, in the form of the racemate or of its optically active isomers, of the general formula ##STR1## wherein A together with...
5618706 Preparation of phytosphingosine derivative  
The invention concerns a process for preparing tetraacetylphytospingosine (TAPS) using F-60-10 mating type strain of Pichia ciferrii. Such strain is subjected to mutagenesis and the high TAPS...
5610140 Bradykinin receptor antagonists with neurokinin receptor blocking activity  
The present invention provides a heterodimeric compound possessing bradykinin and neurokinin receptor antagonist activities useful in the treatment of asthma and other inflammatory diseases...
5610040 Enzymatic synthesis of ceramides and hybrid ceramides  
The present invention provides an efficient method for the production of ceramides and hybrid ceramides via the selective N-acylation of glycosphingolipids by reacting an organic acid or ester...
5605634 Treatment of contaminated groundwater  
The system places traces of nutrients and other treatment substances in the ground, in the path of an on-coming plume of contaminated groundwater. Boreholes placed across the plume contain...
5559020 Process for preparing glyoxylic acid/dialkyl aminomethylphosphonate mixtures  
The invention provides a process for producing mixtures of glyoxylate and a dialkyl aminomethylphosphonate and the subsequent production of N-(phosphonomethyl)glycine, also known as glyphosate. The...
5554518 Stabilized metal-ion-activated L-arginase (L-arginine amidino hydrolase E.C.3.5.3.1)  
An arginase batch capable of producing ornithine with reduced consumption of enzyme. The arginase batch is stabilized by the addition of a reducing agent in at least a 10-fold molar amount relative...
5545542 WB2663 substances and method for their production  
WB2663 substance-producing bacteria belonging to the genus Pseudomonas are cultured to produce a physiologically active substance, from which are isolated neutral substances WB2663A, WB2663B and...
5541091 Process for the biocatalytic coupling of aromatic compounds in the presence of a radical transfer agent  
A process is described for the dimerization of a substituted aromatic compound of the formula (I): ##STR1## wherein X represents --OH, --SH or --NHR where R is H, an alkyl group or an aryl group; R...
5541092 Process for preparing peroxycarboxylic acids using lipase in a non-aqueous medium  
A process for the preparation of a peroxycarboxylic acid of general formula (I), wherein R is an organic residue, in particular a linear or branched alkyled group, an aryl group or an alkyl aryl...
5538874 Phospholipase A1, process for its preparation and the use thereof  
A Phospholipase A1 which is capable of hydrolyzing a phospholipid to produce a 2-acyl lysophospholipid and is obtainable from species of the fungus Aspergillus.
5532149 Removal of phthalyl groups from amides and esters using an amidase isolated from Xanthobacter Agilis  
Phthalyl amidase is an enzyme previously unknown in the art that catalyzes removal of the phthalyl moiety from phthalyl-containing amides. The current invention provides a phthalyl amidase, a...
5521080 Phospholipase A1, process for its preparation  
A method is provided for preparing a Phospholipase A1 which comprises (a) culturing a Phospholipase A1 producing strain of Aspergillus under conditions which allow for the production of the...
5519130 Purification process by decomposition of haloalkanolic acid with dehalogenase  
Haloalkanoic acid impurities are decomposed in the presence of certain surfactants carboxymethyl cellulose or thioglycollic acids salts which may contain them as unconverted reactants by contacting...