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6271005 |
Enzymatic resolution of aminotetralins
Stereoisomers of carbocyclic amine compounds such as amino tetralins are separated by subjecting a mixture of the stereoisomers to reaction with an acylating agent in the presence of the enzyme...
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6268187 |
Process for preparing lysophospholipid using enzyme
The present invention relates to a process for preparing lysophospholipid using enzyme, more specifically, a process for preparing lysophospholipid from glycerol-3-phosphate derivative using lipase...
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6268188 |
Transaminases and aminotransferases
Thermostable transaminase and aminotransferase enzymes derived from various ammonife and aquifex organisms are disclosed. The enzymes are produced from native or recombinant host cells and can be...
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6261798 |
Methods for producing [S,S]-ethylenediamine-N,N'-disuccinate
The present invention relates to a method of producing [S,S]-ethylenediamine-N,N'-disuccinate wherein a microorganism having malate isomerase activity or matter processed therefrom and a...
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6252112 |
Process for the preparation of an enantiomer of a (1R, 4S) or (1S, 4R)-1-amino-4-(hydroxymethyl)-2-cyclopentene derivative
A novel process for the preparation of (1S, 4R)- or (1R, 4S)-4-(2-amino-6-chloro-9H-purin-9-yl)-2 -cyclopentene-1-methanol of the formula ##STR1## is described.
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6242234 |
Mutants of formate dehydrogenase from Candida boidinii, new gene sequences encoding these and use of the new formate dehydrogenases
The invention relates to new mutants of formate dehydrogenase from Candida boidinii, new gene sequences encoding these and use of the new formate dehydrogenases. The wild type FDH used hitherto in...
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6235516 |
Biocatalysts with amine acylase activity
The invention belongs to the field of biotechnology. It concerns a biocatalyst, i.e. a dead or living microorganism or a polypeptide, preferably in isolated form, which exhibits acylase enzymatic...
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6224864 |
Antibiotic 10381A, and process for the preparation of anitbiotics 10381B
Antibiotic 10381a 1 , wherein R is hydrogen, is a cytosine-containing antibiotic producible by culturing the novel microorganism Streptomyces arginensis in an aqueous medium and isolation thereof....
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6225095 |
Enzymatic process for the preparation of (S)-cyanohydrins
Process for the preparation of the (S)-enantiomers of optically active cyanohydrins, in which a reaction mixture of a) an aldehyde or ketone dissolved in an organic, water-immiscible or slightly...
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6221638 |
Process for producing optically active amino compounds
The method for preparing an optically active (R)-amino compound characterized by the method comprising stereoselectively carrying out amino group transfer by action of an (R)-form-specific...
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6210934 |
Gene and gene structure coding for an aminotransferase, and microorganisms which express this gene
The preparation of L-2-amino-4-methylphosphinobutyric acid (L-PPT) by transamination of (3-carboxy-3-oxo-propyl)-methylphosphinic acid with the aid of the L-PPT-specific transaminase from E. coli...
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6204006 |
Microbial strains producing sphingolipid bases
Microbial strains capable of producing enhanced levels of sphingosine, dihydrosphingosine, phytosphingosine and/or derivatives thereof are disclosed. Additionally, there are disclosed methods based...
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6194196 |
Yeast Pichia ciferrii
The present invention relates to a microbiological process for preparing sphingolipids, especially, tetraacetylphytosphingosine(TAPS), using novel yeast cell Pichia ciferrii DSCC 7-25 under optimal...
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6190891 |
Process for producing high-molecular-weight phenolic compounds with myrothecium
A process for macromolecularizing phenolic compounds or aromatic amine compounds by the action of a catalyst comprising an enzyme having a polyphenol oxidizing activity in the alkali region;...
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6187582 |
Process for producing optically active amines
The present invention provides a novel process for producing known optically active amines and optically active acylated amines by: a) in a first step, reacting racemic amines with esters, in...
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6184006 |
Method for the fermentative production of D-pantothenic acid using strains of the family enterobacteriaceae
A method for the production of D-pantothenic acid by the fermentation of microorganisms of the family Enterobacteriacae producing D-pantothenic acid which is characterized in that strains are used...
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6184007 |
Method for the fermentative production of D-pantothenic acid by enhancement of the panD gene in microorganisms
The invention is a method for the production of D-pantothenic acid by the fermentation of microorganisms in which at least the panD gene is enhanced (overexpressed), optionally in combination with...
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6177264 |
Method for the fermentative production of D-pantothenic acid using Coryneform bacteria
The invention discloses three polynucleotide sequences for the fermentative production of D-pantothenic acid. These polynucleotide sequences are genes named panB, encoding a ketopantoate...
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6174711 |
Method for producing L-allysine acetal
A method for producing L-allysine acetal represented by general formula (II), comprising reacting D,L-allysinamide acetal represented by general formula (I) with cells of microorganism or treated...
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6168940 |
Protein having ethylenediamine-N,N'-disuccinic acid:ethylenediamine lyase acitivity and gene encoding the same
The present specification relates to a DNA comprising a nucleotide sequence coding for a polypeptide having ethylenediamine-N,N'-disuccinic acid:ethylenediamine lyase activity, the polypeptide...
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6150146 |
Method for controlled release of compounds having antimicrobial activity and coating composition
A novel method for controlled release of compounds having antimicrobial activity and a novel coating composition capable of controlled release of compounds having antimicrobial activity is...
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6146861 |
Processes for the production of amidase
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6136573 |
Process for producing alkali metal [S,S]-ethylenediamine-n,n'-disuccinates
A process for producing an [S,S]-ethylenediamine-N,N'-disuccinic acid alkali metal salt which comprises reacting fumaric acid with ethylenediamine in an aqueous medium in the presence of an ion of...
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6133018 |
Enzymatic synthesis of chiral amines using -2-amino propane as amine donor
2-Aminopropane is used as the amine donor in the stereoselective synthesis of a chiral amine from a ketone with a transaminase. In a typical embodiment, (S)-1-methoxy-2-aminopropane is prepared by...
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6103508 |
Method for removing fumarase activity, microorganisms obtainable by the method, and production of optically active aminopolycarboxylic acids using the microorganisms
This invention relates to a method for removing fumarase activity from a microorganism or processed product thereof having ethylenediamine-N,N'-disuccinic acid ethylenediamine lyase activity, which...
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6068997 |
Method for the conversion of lecithin into lysolecithin
Conversion of crude lecithin is performed by incubating the lecithin with a lipase-phospholipase mixture in a water/polyol environment. The incubation is carried out at about 40-50° C. and a pH of...
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6066490 |
Nitrilase-producing acidovorax facilis
A process for the preparation of five-membered or six-membered ring lactams from aliphatic α,ω-dinitriles has been developed. In the process an aliphatic α,ω-dinitrile is first converted to an...
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6046042 |
(S)-hydroxynitrilelyase from Hevea brasiliensis
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6037155 |
Process for preparing α-hydroxy acids using microorganism and novel microorganism
A process for preparing α-hydroxy acids represented by the general formula (II): RCH(OH)COOH (wherein R represents a hydrogen atom, an optionally substituted C1-C6 alkyl group, an optionally...
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6022717 |
Use of oxidation promoting chemicals in the oxidation oxidizable galactose type of alcohol configuration containing polymer
Process for the oxidation of the oxidizable galactose type of alcohol in oxidizable galactose type of alcohol configuration containing polymer, such as guar, with galactose oxidase in the presence...
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6015808 |
Synthesis of pharmaceutical compositions with lactams and β-lactams/oxo thia azabicyclo compounds
Pharmaceutical compositions with heretofore unknown and enhanced physical, chemical, and biological properties are prepared by combining known biologically active parent compounds with oxo thia...
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6013829 |
Process for the asymmetric synthesis of S-acyl derivatives of 2-mercaptomethyl -3- phenyl propanoic acid, application to the synthesis of N-(mercaptoacyl) amino acid derivatives
Process for the asymmetric synthesis of S-acyl derivatives of 2-mercaptomethyl-3-phenylpropanoic acid of formula (I): characterized in that it comprises the steps consisting in: a) preparing the...
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6005066 |
Aliphatic polyester composition
A polymer composition comprises an aliphatic polyester and at least one compound of the general formula (I): R 1 a (A)R 2 b , where A is a polyfunctional hydrocarbon group; R1 is an...
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6001615 |
Enzymatic reduction of ketone groups in 6-cyano-3,5-dihydroxy-hexanoic alkyl ester
A compound of formula (III) ##STR1## is produced by selectively reducing a compound of formula (II) ##STR2## using a reductase possessing the properties of one produced by Beauveria, Candida,...
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5994105 |
Epimerase
A novel polypeptide, acylglucosamine 2-epimerase as shown in FIG. 1 and derivatives thereof, DNA coding for said enzyme, a recombinant vector containing said enzyme, a transformant integrated...
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5989900 |
Process for preparing optically active allylic alcohol derivatives
A process for preparing optically active allylic alcohol derivatives comprises reacting a racemic mixture of the following formula I ##STR1## wherein R is alkyl, alkenyl, or substituted or...
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5986077 |
Process for producing anthracyclines and intermediates thereof
A process for producing anthracyclines and intermediates thereof expressing in a foreign Streptomyces host a DNA fragment relating to the biosynthetic pathway of anthracyclines and, if desired,...
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5985626 |
Catalytic antibody/substrate intermediates
Antibodies that catalyze the aldol reaction are generated by immunization with a reactive compound that covalently traps a Lysine (Lys) residue in the binding pocket of the antibody by formation of...
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5985274 |
Antibiotic 10381A.sub.1 and process for the preparation of antibiotics 10381B
Antibiotic 10381a 1 , wherein R is hydrogen, is a cytosine-containing antibiotic producible by culturing the novel microorganism Streptomyces arginensis in an aqueous medium and isolation thereof....
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5981267 |
Enantioselection of amines using homocarbonates with hydrolase
Racemic amines are enzymically converted by enantioselective carbamation to produce to chiral carbamates. Simple homocarbonates employed as substrates. The chiral carbamates may then be deprotected...
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5973203 |
Process for preparation of acrylic or methacrylic acid amides
A process for preparing acrylic or methacrylic acid amides functionalized with a cationizable tertiary amine, by aminolysis of acrylic or methacrylic acid esters with the aid of enzymes.
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5962283 |
Transminases and amnotransferases
Thermostable transaminase and aminotransferase enzymes derived from various ammonifex, aquifex and pyrobaculum organisms are disclosed. The enzymes are produced from native or recombinant host...
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5958742 |
Microbiological method for preparing sphingolipids using a novel yeast pichia ciferrii DSCC 7-25
The present invention relates to a microbiological process for preparing sphingolipids, especially, tetraacetylphytosphingosine(TAPS), using novel yeast cell Pichia ciferrii DSCC 7-25 under optimal...
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5955327 |
Process for manufacturing vegetable lysolecithins
In accordance with the present invention, there is provided a process for manufacturing vegetable lysolecithins which comprises allowing a hydrolysis enzyme consisting of phospholipase A 1 or A 2 ...
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5945316 |
Lactic-acid-containing cyclic depsipeptides having 18 ring atoms as endoparasiticidal agents, and process for their preparation
The present invention relates to a process for the preparation of lactic-acid-containing, optically active, cyclic depsipeptides having 18 ring atoms with the aid of fungal strains of the species...
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5945315 |
Method for producing cryptophycins by cultivating a Nostoc sp.
The present invention provides novel cryptophycin compounds having the following structure: ##STR1## The present invention also provides methods for producing cryptophycins from the Nostoc sp. of...
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5935844 |
Porous cellulose carrier for immobilizing microorganisms to convert nitrogen compounds
A carrier for immobilizing microorganisms is prepared by producing a porous cellulose derivative by reacting porous cellulose such as foamed cellulose with a compound selected from the group...
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5912152 |
Process for preparing sphingomyelin and ceramide from erythrocyte as a starting material and a curing agent or cosmetic formulated with ceramide
A process for the preparation of ceramide by using erythrocytes as a starting material is disclosed herein. For the purpose of obtaining ceramide at a low cost and in a large amount, ceramide is...
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5900368 |
Process for bioreduction of bisaryl ketone to bisaryl alcohol
The present invention is directed to an improved process for making PDE IV inhibitors. In specific, this application describes a process for making and purifying a chiral bisaryl alcohol, an...
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5885809 |
Method of producing (S)-cyanohydrins
A method for producing (S)-cyanohydrins of general formula ##STR1## in which R and R' independently represent (1) hydrogen; (2) a substituted or unsubstituted saturated alkyl group which may...
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