|
Match
|
Document |
Document Title |
|
|
5534422 |
Bioconversion of beta keto-ester to (R) hydroxyester
A biotransformation process for the production of an intermediate used in the chemical synthesis of an antibiotic compound.
|
|
|
5527702 |
Callus cell induction from partially submerged explant tissue in liquid medium for preparation of taxanes
A method for the induction of callus cells capable of producing taxanes from explant tissue by partially submerging the explant tissue in a liquid culture medium on a membrane raft, resulting in...
|
|
|
5457036 |
Process for production of C.sub.10 and/or C.sub.12 gamma-lactones from the corresponding C.sub.10 and/or C.sub.12 carboxylic acids by means of microbial biotransformation in the presence of mineral oil
Described is a process for producing C 10 and/or C 12 gamma-lactones from the corresponding C 10 and/or C 12 carboxylic acids by use of microorganisms of the genus Mortierella, whereby a...
|
|
|
5455174 |
Process for the stereoselective esterification of ascorbic or erythorbic acids with long-chained enol esters
An organic acid ester of ascorbic acid or erythorbic acid is produced by reacting ascorbic acid or erythorbic acid with an organic acid enol ester in an organic solvent with a solubility of...
|
|
|
5444087 |
Manumycin compounds
Manumycin C, Manumycin D and Manumycin E, obtainable by cultivation of a strain of Streptomyces sp. A.T.C.C. No. 55484, oxidized derivatives thereof and salts and prodrugs of these compounds. The...
|
|
|
5372940 |
D-pantolactone hydrolase and process for the preparation thereof
The invention is drawn to a new enzyme that selectively hydrolyzes D-pantolactone in D,L-pantolactone and has the following characteristics: (a) action: acts on pantolactone to produce the...
|
|
|
5342767 |
Lactobacillus kefir alcohol dehydrogenase
The present invention discloses the preparation of R-configured trialkylsilylethynyl α-alcohols from similarly substituted α-ketones, and vice versa, catalyzed by the alcohol dehydrogenase of...
|
|
|
5284870 |
Aldose reductase inhibitor
The present invention relates to an aldose reductase inhibitor represented by the formula: ##STR1## wherein R 1 is (CH 2 ) 2 COOH and R 2 is phenyl or p-hydroxyphenyl, or R 1 and R 2 are...
|
|
|
5284759 |
Biological production of acetal or ketal substituted benzene compounds
Meta-hydroxyphenylacetylenes are produced from phenyl-substituted ketal or acetal precursors. Using biotransformation processes, these precursors serve as substrates that are converted to...
|
|
|
5275949 |
Process for the preparation of D-pantolactone
A process for the preparation of D-pantolactone, comprising employing specific microorganisms to convert D,L-pantolactone as the starting material into D-pantoic acid by selective asymmetric...
|
|
|
5274128 |
Octalactone-containing composition, fermentation process for producing same and organoleptic uses thereof
Described is a process for the preparation of compositions of matter containing octalactones defined according to the structure: ##STR1## which includes the stereoisomers having the structures:...
|
|
|
5252472 |
Process for the production of furans and lactones from streptomyces
It is possible with the aid of various Streptomycetes species to prepare new compounds having a furan or lactone structure. These compounds have a pharmacological, especially antibiotic, action.
|
|
|
5248609 |
Racemic separation of 7α-acyloxy-6β-hydroxymethyl-2-oxabicyclo[3.]-octan-3-ones by stereospecific enzymatic acylate hydrolysis
The invention relates to a process for the production of optically active (-)-oxabicyclo[3.3.0]octanolones of formula (-)-I ##STR1## wherein R is defined herein, comprising subjecting a racemic...
|
|
|
5236832 |
Microbiological oxidation of methyl groups in heterocycles
A microbiological process for the oxidation of methyl groups in aromatic 5- or 6-member ring heterocycles to the corresponding carboxylic acid. The heterocycle serves as the substrate and exhibits...
|
|
|
5231198 |
Asymmetric synthesis of hexahydrodibenzofurans by stereospecific inversion of ortho substituted 2-phenylcyclohexanols
This invention relates to the stereospecific process for the preparation, separation and purification of hexahydrodibenzofurans which are used in the preparation of the 5HT 3 compounds. More...
|
|
|
5219743 |
Method for optical resolution of Corey lactone diols
The primary hydroxy group of Corey lactone diols is optically selectively acylated to obtain the desired optically active ester and/or diol. The mixture of Corey lactone diols of formulae (Ia) and...
|
|
|
5219742 |
Method of producing gamma-hydroxydecanoic acid or its lactone by feeding a ricinoleic acid source to sp. odorus or rh. glutinis
Gamma-decalactone is obtained from a source of ricinoleic acid, for example castor oil, by incubation with Sp. odorus or Rh. glutinis. The product lactone is obtained by lactonising the product...
|
|
|
5217884 |
Hydroxylation of methyl groups in aromatic heterocycles by microorganisms
A process using microorganisms which contain genes, which form an active xylene monooxygenase, which form no effective, chromosomally or plasmid-coded alcohol hydrogenase, and which are, thus,...
|
|
|
5215901 |
Process for producing delta-lactones from 11-hydroxy fatty acids
The invention provides a process for producing delta-lactones useful for incorporation in flavourings and fragrances, wherein a micro-organism which is preferably acceptable for making "food grade"...
|
|
|
5213973 |
Microbiological process for oxidation of methyl groups
A microbiological process for oxidation of methyl groups in aromatic 5- or 6-ring heterocycles to the corresponding carboxylic acid. The reaction of the heterocycle takes place by microorganisms of...
|
|
|
5212078 |
Process for producing a lactone
Described is a microbiological method for producing the lactone, sclareolide having the structure: ##STR1## and a diol having the chemical structure: ##STR2## using a sclareol derivative having one...
|
|
|
5209826 |
Method of separating sesamin and episesamin
A steam stripping fraction of sesame seed oil with increased concentration of sesamin and episesamin is used in a molecular distillation process to obtain a fraction containing more than 70 weight...
|
|
|
5190867 |
Process for the preparation of R-2,2-R.sub.1,R.sub.2 -1,3-dioxolane-4-methanol
Process for the preparation of R-2,2-R 1 ,R 2 -1,3-dioxolane-4-methanol wherein R 1 and R 2 are H or alkyl groups or wherein R 1 and R 2 together with the carbon atom to which they are...
|
|
|
5182209 |
Enantioselective preparation of s-2R.sub.1,2R.sub.2 -1,3-dioxolane-4-methanol and derivatives thereof
Process for the enantioselective conversion of an enantiomer mixture of 2R 1 ,2R 2 -1,3-dioxolane-4-methanol including the following steps: combining the enantioselective enzyme, PQQ-dependent...
|
|
|
5182198 |
Process for preparing (+)-homopilopic acid
A process for preparing (+)-homopilopic acid and the salts thereof which comprises hydrolyzing a mixture of (+)-homopilopic acid ester of the general formula (I): ##STR1## wherein R 1 denotes...
|
|
|
5179012 |
Process for the production and extraction of antioxidants from a micro-organism culture
The process consists of culturing in a closed photobioreactor (2) microalgae suspended in a culture medium (1), the oxygen produced by the microalgae by photosynthesis being collected and then...
|
|
|
5168054 |
Process for the microbiological production of gamma- and delta-lactones
Process for the production of gamma- or delta-lactones according to the general formula: ##STR1## in which R is a saturated, mono-, di- or triunsaturated linear alkyl chain comprising from 2 to 10...
|
|
|
5155028 |
Process for the enzymatic cleavage of vinyl 2-aryl-propionates
In the enzymatic stereoselective ester cleavages of 2-arylpropionate, the reaction rate of the hydrolyzing enzymes can be drastically increased if the vinyl ester of the 2-arylpropionate is...
|
|
|
5143832 |
ATCC 53620 production of a triacetylenic dioxolone with Microbispora sp. SCC 1438
The novel triacetylenic dioxolone antifungal compound of this invention is isolated from the EV-22 complex of this invention which is elaborated by the microorganism Microbispora sp. SCC 1438, ATCC...
|
|
|
5122461 |
Preparation of pyrocatecholic compounds
The invention relates to a novel method for preparing pyrocatecholic compounds from monophenolic compounds using catalysis by monophenol monooxygenase in an aqueous solution containing metal ions....
|
|
|
5120647 |
Phospholipase A.sub.2 inhibitor
A compound of the formula (I): ##STR1## wherein R 1 , R 2 , and R 3 are --COOR 4 , --COOR 5 , and --COOR 6 , respectively; R 4 , R 5 , and R 6 each is hydrogen, lower alkyl, or alkali metal; W is...
|
|
|
5102794 |
Novel substance for agricultural use
Substance F-0368 of the formula: ##STR1## or salts thereof is prepared by culturing Kitasatosporia sp. F-0368 in a culture medium thereby producing substance F-0368, and then isolating and...
|
|
|
5084392 |
Process for producing optically active hydroxy lactones
The invention provides a method for producing an optically active hydroxy lactone which comprises reacting under substantially anhydrous conditions and in the presence of an enzyme an ester and a...
|
|
|
5079153 |
Process for the preparation of organic esters of ascorbic acid or erythorbic acid using ester hydralases in organic solvents containing 100-10,000 ppm of water
A process for the preparation of an organic ester of ascorbic acid or erythorbic acid represented by the general formula (II) or (III): ##STR1## wherein R 1 is alkyl, aralkyl, or aryl, by reacting...
|
|
|
5077203 |
Enzymatic process for the preparation of deoxyketoses
The invention relates to a process for the preparation of compounds of formula CH 3 (CHOH) n --COCH 2 OH in which n is an integer from 1 to 4, wherein L-serine, glyoxylic acid and an aldehyde...
|
|
|
5071753 |
Process for the enzymatic preparation of organic esters of ascorbic acid or erythorbic acid
A process for the preparation of an organic ester of ascorbic acid or erythorbic acid represented by the general formula (II) or (III): ##STR1## wherein R 1 is alkyl, aralkyl, or aryl, by reacting...
|
|
|
5045458 |
Antibiotics PB-6042S
A compound of the formula (I): ##STR1## wherein R is: (CH 2 ) 8 CH 3 , (CH 2 ) 3 CH (cis) CH(CH 2 ) 5 CH 3 , (CH 2 ) 10 CH 3 , or (CH 2 ) 4 CH (cis) CH(CH 2 ) 6 CH 3 . or salt...
|
|
|
5043354 |
Pharmaceutically useful 5-hydroxy-2,3-dihydro-benzofurans and 5-hydroxy-benzofurans
A compound of the formula: ##STR1## wherein R 1 , R 2 and R 3 are each lower alkyl, R 4 is hydrogen or hydroxy, and a heavy solid line means a double bond when R 4 is hydrogen and a single bond...
|
|
|
5032513 |
Process for the preparation of gamma and delta lactones
A process for the preparation of gamma and delta lactones from organic carboxylic acids or derivatives thereof is disclosed. The process comprises cultivating, under aerobic conditions, a fungus of...
|
|
|
5026642 |
Process for the enzymatic production of ketones
In a process for the reduction of ketones, the keto compounds are enantioselectively reduced to give secondary alcohols by means of microorganisms. Keto compounds of the formula R 3 NH--CHR 1 ...
|
|
|
4983587 |
Dihydrodibenzofuran derivatives and fungicides containing these compounds
Substituted benzofuran derivatives of the formula ##STR1## where R 1 , R 2 and R 3 are hydrogen, an alkali or alkaline earth metal, alkyl, aralkyl, alkanoyl, halogen-substituted alkanoyl, benzoyl...
|
|
|
4970163 |
Process for producing diol and lactone and microorganisms capable of same
Described is a microbilogical method for producing the lactone, sclareolide and a diol having the chemical structure: ##STR1## using sclareol having the structure: ##STR2## as a substrate and using...
|
|
|
4956383 |
Antifungal triacetylenic dioxolone from Microbispora sp. SCC 1438, ATCC 53620
The novel triacetylenic dioxolone antifungal compound of this invention is isolated from the EV-22 complex of this invention which is elaborated by the microorganism Microbispora sp. SCC 1438, ATCC...
|
|
|
4956285 |
Process for the preparation of S-2,2-R.sub.1,R.sub.2 -1,3 -dioxolane-4-methanols
A process for the preparation of an enriched S-isomer of a 2,2-R 1 ,R 2 -1,3-dioxolane-4-methanol of the formula ##STR1## wherein R 1 and R 2 are individually selected from the group consisting...
|
|
|
4945052 |
Production of a Vitamin C precursor using genetically modified organisms
An enzyme for conversion of 2,5-diketo-D-gluconate (2,5-DKG) to 2-keto-L-gulonic acid (2-KLG) and a genetically modified organism that expresses all the fermentation enzymes needed to convert...
|
|
|
4931399 |
Process for preparing optically-active glycerol ketal derivatives
The invention relates to a method for microbiologically resolving racemic 2,3-o-substituted glycerol esters to obtain optically activated 2,3-o-substituted glycerol with remaining esters also being...
|
|
|
4885246 |
Optically active carbacyclin intermediates and processes for the preparation thereof
New intermediate, an optically active (1S,5R)-7,7-alkylenedioxy-2-alkoxycarbonylbicyclo[3.3.0]octa
n-3-one which is useful for the synthesis of an optically active carbacyclin. This intermediate is...
|
|
|
4837399 |
Napthoquinone antibiotics from fuserium solani
Three naphthoquinones isolated from cultures of Fusarium solani were found to be effective antibiotics against gram-positive bacteria. Controlling the dissolved oxygen concentration in the...
|
|
|
4830967 |
Process for producing antibiotic A80438
A new strain of Streptomyces pactum, NRRL 15970, and an improved fermentation process for producing the polyether antibiotic A80438 using this microorganism are provided.
|
|
|
4798799 |
Process for producing diol and furan and microorganism capable of same
The invention provides a microbiological method for preparing diol and furan compounds from a variety of substrates using the microorganism Hyphozyma roseoniger, CBS 214.83 and ATCC 20624.
|